Anders A. Jensen

Anders A. Jensen

Professor


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  1. 2024
  2. E-pub ahead of print

    Discovery and Structure-Activity Relationships of 2,5-Dimethoxyphenylpiperidines as Selective Serotonin 5-HT2A Receptor Agonists

    Marcher, Emil, Jensen, Anders A., Smits, G., Frydenvang, Karla Andrea & Kristensen, Jesper Langgaard, 2024, (E-pub ahead of print) In: Journal of Medicinal Chemistry.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2023
  4. Published

    The Concise Guide to PHARMACOLOGY 2023/24: Ion channels

    Alexander, S. P. H., Mathie, A. A., Peters, J. A., Veale, E. L., Striessnig, J., Kelly, E., Armstrong, J. F., Faccenda, E., Harding, S. D., Davies, J. A., Aldrich, R. W., Attali, B., Baggetta, A. M., Becirovic, E., Biel, M., Bill, R. M., Caceres, A. I., Catterall, W. A., Conner, A. C., Davies, P. & 53 others, De Clerq, K., Delling, M., Di Virgilio, F., Falzoni, S., Fenske, S., Fortuny-Gomez, A., Fountain, S., George, C., Goldstein, S. A. N., Grimm, C., Grissmer, S., Ha, K., Hammelmann, V., Hanukoglu, I., Hu, M., Ijzerman, A. P., Jabba, S. V., Jarvis, M., Jensen, Anders A., Jordt, S. E., Kaczmarek, L. K., Kellenberger, S., Kennedy, C., King, B., Kitchen, P., Liu, Q., Lynch, J. W., Meades, J., Mehlfeld, V., Nicke, A., Offermanns, S., Perez-Reyes, E., Plant, L. D., Rash, L., Ren, D., Salman, M. M., Sieghart, W., Sivilotti, L. G., Smart, T. G., Snutch, T. P., Tian, J., Trimmer, J. S., Van den Eynde, C., Vriens, J., Wei, A. D., Winn, B. T., Wulff, H., Xu, H., Yang, F., Fang, W., Yue, L., Zhang, X. & Zhu, M., 2023, In: British Journal of Pharmacology. 180 , Suppl 2, p. S145-S222

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Evolutionary conservation of Zinc-Activated Channel (ZAC) functionality in mammals: a range of mammalian ZACs assemble into cell surface-expressed functional receptors

    Jensen, Anders A., 2023, In: Frontiers in Molecular Biosciences. 10, 11 p., 1265429.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Repeated low doses of psilocybin increase resilience to stress, lower compulsive actions, and strengthen cortical connections to the paraventricular thalamic nucleus in rats

    Kiilerich, K. F., Lorenz, J., Scharff, M. B., Speth, N., Brandt, T. G., Czurylo, J., Xiong, M., Jessen, N. S., Casado-Sainz, A., Shalgunov, Vladimir, Kjærby, Celia, Satała, G., Bojarski, A. J., Jensen, Anders A., Herth, Matthias Manfred, Cumming, P., Overgaard, A. & Palner, M., 2023, In: Molecular Psychiatry. 28, 9, p. 3829-3841

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Introducing Conformational Restraints on 25CN-NBOH: A Selective 5-HT2A Receptor Agonist

    Marcher, Emil, Nykodemová, J., Harpsøe, Kasper, Jensen, Anders A. & Kristensen, Jesper Langgaard, 2023, In: ACS Medicinal Chemistry Letters. 14, 3, p. 319–325

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Structure–Activity Assessment and In-Depth Analysis of Biased Agonism in a Set of Phenylalkylamine 5-HT2A Receptor Agonists

    Pottie, E., Poulie, Christian Bernard Matthijs, Simon, Icaro A, Harpsøe, Kasper, D’Andrea, L., Komarov, I. V., Gloriam, David E., Jensen, Anders A., Kristensen, Jesper Langgaard & Stove, C. P., 2023, In: ACS Chemical Neuroscience. 14, 15, p. 2727–2742

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    In Vitro and In Vivo Evaluation of Pellotine: A Hypnotic Lophophora Alkaloid

    Poulie, C. B. M., Chan, C. B., Parka, A., Lettorp, M., Vos, J., Raaschou, A., Pottie, E., Bundgaard, M. S., Sørensen, L. M. E., Cecchi, C. R., Märcher-Rørsted, E., Bach, A., Herth, M. M., Decker, A., Jensen, A. A., Elfving, B., Kretschmann, A. C., Stove, C. P., Kohlmeier, K. A., Cornett, C. & 3 others, Janfelt, Christian, Kornum, Birgitte Rahbek & Kristensen, Jesper Langgaard, 2023, In: ACS Pharmacology & Translational Science. 6, 10, p. 1492-1507

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Ligand selectivity hotspots in serotonin GPCRs

    Simon, Icaro A, Bjørn-Yoshimoto, Walden, Harpsøe, Kasper, Iliadis, S., Svensson, B., Jensen, Anders A. & Gloriam, David E., 2023, In: Trends in Pharmacological Sciences. 44, 12, p. 978-990

    Research output: Contribution to journal › Review › Research › peer-review

  11. Published

    Identification of 5-HT2 Serotonin Receptor Modulators through the Synthesis of a Diverse, Tropane- and Quinuclidine-alkaloid-Inspired Compound Library

    Yao, R., Jensen, Anders A., Bryce-Rogers, H. P., Schultz-Knudsen, Katrine, Zhou, L., Hovendal, N. P., Pedersen, H., Kubus, M., Ulven, Trond & Laraia, L., 2023, In: Journal of Medicinal Chemistry. 66, 16, p. 11536-11554

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Discovery of a Novel Class of Benzimidazole-Based Nicotinic Acetylcholine Receptor Modulators: Positive and Negative Modulation Arising from Overlapping Allosteric Sites

    Zhou, L., Dau, V. & Jensen, Anders A., 2023, In: Journal of Medicinal Chemistry. 66, 17, p. 12586–12601

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. 2022
  14. Published

    Discovery of the First Highly Selective Antagonist of the GluK3 Kainate Receptor Subtype

    Chałupnik, P., Vialko, A., Pickering, Darryl S, Hinkkanen, M., Donbosco, S., Møller, T. C., Jensen, Anders A., Nielsen, Birgitte, Bay, Y., Kristensen, Anders Skov, Johansen, Tommy Nørskov, Łątka, K., Bajda, M. & Szymańska, E., 2022, In: International Journal of Molecular Sciences. 23, 15, 16 p., 8797.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Discovery of β-Arrestin-Biased 25CN-NBOH-Derived 5-HT2A Receptor Agonists

    Poulie, Christian Bernard Matthijs, Pottie, E., Simon, Icaro A, Harpsøe, Kasper, D'Andrea, L., Komarov, I. V., Gloriam, David E., Jensen, Anders A., Stove, C. P. & Kristensen, Jesper Langgaard, 2022, In: Journal of Medicinal Chemistry. 65, 18, p. 12031–12043

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Strychnine and its mono- and dimeric analogues: a pharmaco-chemical perspective

    Zlotos, D. P., Mandour, Y. M. & Jensen, Anders A., 2022, In: Natural Product Reports. 39, 10, p. 1910-1937

    Research output: Contribution to journal › Review › Research › peer-review

  17. 2021
  18. Published

    The concise guide to pharmacology 2021/22: Ion channels

    Alexander, S. P., Mathie, A., Peters, J. A., Veale, E. L., Striessnig, J., Kelly, E., Armstrong, J. F., Faccenda, E., Harding, S. D., Pawson, A. J., Southan, C., Davies, J. A., Aldrich, R. W., Attali, B., Baggetta, A. M., Becirovic, E., Biel, M., Bill, R. M., Catterall, W. A., Conner, A. C. & 38 others, Davies, P., Delling, M., Virgilio, F. D., Falzoni, S., Fenske, S., George, C., Goldstein, S. A. N., Grissmer, S., Ha, K., Hammelmann, V., Hanukoglu, I., Jarvis, M., Jensen, Anders A., Kaczmarek, L. K., Kellenberger, S., Kennedy, C., King, B., Kitchen, P., Lynch, J. W., Perez-Reyes, E., Plant, L. D., Rash, L., Ren, D., Salman, M. M., Sivilotti, L. G., Smart, T. G., Snutch, T. P., Tian, J., Trimmer, J. S., Van den Eynde, C., Vriens, J., Wei, A. D., Winn, B. T., Wulff, H., Xu, H., Yue, L., Zhang, X. & Zhu, M., 2021, In: British Journal of Pharmacology. 178 , Suppl. 1, p. S157-S245

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Erythrina Alkaloid Analogues as nAChR Antagonists-A Flexible Platform for Leads in Drug Discovery

    Clementson, S., Matheu, S. A., Marcher, Emil, Pedersen, H., Jensen, Anders A., Clausen, Rasmus Prætorius, Vital, P., Glibstrup, E., Jessing, M. & Kristensen, Jesper Langgaard, 2021, In: The Journal of Organic Chemistry. 86, 12, p. 8248-8262

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Delineation of the functional properties exhibited by the Zinc-Activated Channel (ZAC) and its high-frequency Thr128Ala variant (rs2257020) in Xenopus oocytes

    Madjroh, Nawid, Davies, P. A., Smalley, J. L., Kristiansen, Uffe, Söderhielm, P. C. & Jensen, Anders A., 2021, In: Pharmacological Research. 169, 18 p., 105653.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Discovery and functional characterization of N-(thiazol-2-yl)-benzamide analogs as the first class of selective antagonists of the Zinc-Activated Channel (ZAC)

    Madjroh, Nawid, Mellou, E., Davies, P. A., Söderhielm, P. C. & Jensen, Anders A., 2021, In: Biochemical Pharmacology. 193, 16 p., 114782.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Probing the molecular basis for signal transduction through the Zinc-Activated Channel (ZAC)

    Madjroh, Nawid, Mellou, E., Æbelø, L., Davies, P. A., Söderhielm, P. C. & Jensen, Anders A., 2021, In: Biochemical Pharmacology. 193, 18 p., 114781.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    25CN-NBOH: A selective agonist for in vitro and in vivo investigations of the serotonin 2A receptor

    Marcher, Emil, Jensen, Anders A. & Kristensen, Jesper Langgaard, 2021, In: ChemMedChem. 16, 21, p. 3263-3270

    Research output: Contribution to journal › Review › Research › peer-review

  24. Published

    C-2-Linked Dimeric Strychnine Analogues as Bivalent Ligands Targeting Glycine Receptors

    Zlotos, D. P., Abdelmalek, C. M., Botros, L. S., Banoub, M. M., Mandour, Y. M., Breitinger, U., El Nady, A., Breitinger, H., Sotriffer, C., Villmann, C., Jensen, Anders A. & Holzgrabe, U., 2021, In: Journal of Natural Products. 84, 2, p. 382-394

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. 2020
  26. Published

    Functional characterization of 5-HT1A and 5-HT1B serotonin receptor signaling through G-protein-activated inwardly rectifying K+ channels in a fluorescence-based membrane potential assay

    Gadgaard, C. & Jensen, Anders A., 2020, In: Biochemical Pharmacology. 175, 13 p., 113870.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    The selective 5-HT2A receptor agonist 25CN-NBOH: structure-activity relationship, in vivo pharmacology, and in vitro and ex vivo binding characteristics of [3H]25CN-NBOH

    Jensen, Anders A., Halberstadt, A. L., Marcher, Emil, Odland, Anna Ulstein, Chatha, M., Speth, N., Liebscher, G., Hansen, M., Bräuner, Hans, Palner, M., Andreasen T., Jesper & Kristensen, Jesper Langgaard, 2020, In: Biochemical Pharmacology. 177, 16 p., 113979.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    β-Indolyloxy Functionalized Aspartate Analogs as Inhibitors of the Excitatory Amino Acid Transporters (EAATs)

    Liu, N., Jensen, Anders A. & Bunch, Lennart, 2020, In: ACS Medicinal Chemistry Letters. 11, 11, p. 2212-2220 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Pharmacological Characterization of the Zinc-Activated Channel: A Cys-Loop Receptor Gated by Zn2+, Cu2+ and Protons

    Madjroh, Nawid, Jensen, Anders A. & Davies, P. A., 7 Feb 2020, p. 582A-582A.

    Research output: Contribution to conference › Conference abstract for conference › Research

  30. Published

    Investigation of the 2,5-dimethoxy motif in phenethylamine Serotonin 2A receptor agonists

    Marcher, Emil, Halberstadt, A. L., Klein, A. K., Chatha, M., Jademyr, S., Jensen, Anders A. & Kristensen, Jesper Langgaard, 2020, In: ACS Chemical Neuroscience. 11, p. 1238-1244

    Research output: Contribution to journal › Letter › Research › peer-review

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ID: 1298436