Anders Bach

Anders Bach

Associate Professor


  1. 2021
  2. E-pub ahead of print

    Deconstructing Noncovalent Kelch-like ECH-Associated Protein 1 (Keap1) Inhibitors into Fragments to Reconstruct New Potent Compounds

    Pallesen, J. S., Narayanan, Dilip, Tran, K. T., Solbak, S. M. Ø., Marseglia, G., Sørensen, L. M. E., Høj, Lars Jakobsen, Munafò, F., Carmona, R. M. C., Garcia, A. D., Desu, H. L., Brambilla, R., Johansen, Tommy Nørskov, Popowicz, G. M., Sattler, M., Gajhede, Michael & Bach, Anders, 5 Apr 2021, In : Journal of Medicinal Chemistry.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. E-pub ahead of print

    Selective release of gastrointestinal hormones induced by an orally active GPR39 agonist

    Grunddal, K. V., Diep, T. A., Petersen, N., Tough, I. R., Skov, Louise Julie, Liu, Lingzhi, Buijink, J. A., Mende, F., Jin, C., Jepsen, S. L., Sørensen, L. M. E., Achiam, Michael Patrick, Strandby, R. B., Bach, Anders, Hartmann, Bolette, Frimurer, Thomas Michael, Hjorth, Siv Annegrethe, Bouvier, M., Cox, H. & Holst, Birgitte, Mar 2021, In : Molecular Metabolism. p. 101207

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2020
  5. E-pub ahead of print

    Identification of novel fragments binding to the PDZ1-2 domain of PSD-95

    Zang, Jie, Ye, F., Solbak, S., Høj, Lars Jakobsen, Zhang, M. & Bach, Anders, 11 Dec 2020, In : ChemMedChem.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    The dynamics of linear polyubiquitin

    Jussupow, A., Messias, A. C., Stehle, R., Geerlof, A., Solbak, S. M. Ø., Paissoni, C., Bach, Anders, Sattler, M. & Camilloni, C., Oct 2020, In : Science Advances. 6, 42, 13 p., eabc3786.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    A high-affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain

    Christensen, N. R., De Luca, M., Lever, M. B., Richner, M., Hansen, A. B., Noes-Holt, Gith, Jensen, Kathrine Louise, Rathje, Mette, Jensen, Dennis Bo, Erlendsson, Simon, Bartling, Christian Reinhard Otto, Ammendrup-Johnsen, I., Pedersen, S. E., Schönauer, M., Nissen, K. B., Midtgaard, S. R., Teilum, Kaare, Arleth, Lise, Sørensen, Andreas Toft, Bach, Anders, Strømgaard, Kristian, Meehan, Claire Francesca, Vægter, C. B., Gether, Ulrik & Madsen, Kenneth Lindegaard, 2020, In : EMBO Molecular Medicine. 12, 6, 25 p., e11248.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Conjugation of Therapeutic PSD-95 Inhibitors to the Cell-Penetrating Peptide Tat Affects Blood-Brain Barrier Adherence, Uptake, and Permeation

    Kristensen, Mie, Kucharz, Krzysztof, Alves Fernandes, Eduardo Felipe, Strømgaard, Kristian, Schallburg Nielsen, M., Cederberg Helms, H. C., Bach, Anders, Ulrikkaholm Tofte-Hansen, M., Aldana Garcia, Blanca Irene, Lauritzen, Martin & Larsen, Birger Brodin, 2020, In : Pharmaceutics. 12, 7, 24 p., 661.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Developing Inhibitors of the p47phox-p22phox Protein-Protein Interaction by Fragment-Based Drug Discovery

    Solbak, S. M. Ø., Zang, Jie, Narayanan, Dilip, Høj, Lars Jakobsen, Bucciarelli, S., Softley, C., Meier, S., Langkilde, Annette Eva, Gotfredsen, C. H., Sattler, M. & Bach, Anders, 2020, In : Journal of Medicinal Chemistry. 63, 3, p. 1156-1177

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2019
  11. Published

    Selectivity, efficacy and toxicity studies of UCCB01-144, a dimeric neuroprotective PSD-95 inhibitor

    Bach, Anders, Clausen, B. H., Kristensen, L. K., Andersen, M. G., Ellman, D. G., Hansen, P. B. L., Hasseldam, Henrik, Heitz, M., Özcelik, D., Tuck, E. J., Kopanitsa, M. V., Grant, S. G. N., Lykke-Hartmann, K., Johansen, Flemming Fryd, Lambertsen, K. L. & Strømgaard, Kristian, May 2019, In : Neuropharmacology. 150, p. 100-111 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    A Comparative Assessment Study of Known Small-Molecule Keap1-Nrf2 Protein-Protein Interaction Inhibitors: Chemical Synthesis, Binding Properties, and Cellular Activity

    Tran, K. T., Pallesen, J. S., Solbak, S. M. Ø., Narayanan, Dilip, Baig, A., Zang, Jie, Aguayo Orozco, Alejandro, Carmona, R., Garcia, A. & Bach, Anders, 2019, In : Journal of Medicinal Chemistry. 62, 17, p. 8028-8052

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Molecular architecture of the Jumonji C family histone demethylase KDM5B

    Dorosz, J., Kristensen, L. H., Aduri, N. G., Mirza, Osman Asghar, Lousen, R., Bucciarelli, S., Mehta, V., Sellés Baiget, Selene, Solbak, S. M. Ø., Bach, Anders, Mesa, Pablo, Hernandez, P. A., Montoya, Guillermo, Nguyen, T. T. T. N., Rand, Kasper Dyrberg, Boesen, T. & Gajhede, Michael, 2019, In : Scientific Reports. 9, 13 p., 4019.

    Research output: Contribution to journalJournal articleResearchpeer-review

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