Annette Eva Langkilde

Annette Eva Langkilde

Associate Professor

ORCID: 0000-0003-2467-4205

Publication year:
All
1 - 25 out of 41Page size: 25
  1. 2023
  2. Published

    Identifying Biological and Biophysical Features of Different Maturation States of α-Synuclein Amyloid Fibrils

    Skamris, T., Vestergaard, Bente, Madsen, Kenneth Lindegaard, Langkilde, Annette Eva & Foderà, Vito, 2023, In: Methods in molecular biology (Clifton, N.J.). 2551, p. 321-344 24 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Intrinsically Disordered Proteins as an Instrument for Research-Integrating Teaching

    Skriver, K., Sjørup, S. A., Langkilde, A. E., Balouka, E., Christensen, C. S., Carbel, K., Decker, J. N. V., Essenbæk, D. N., Gräf, J. F., Jessen, C. H., Kristensen, P., Merrild, C., Mortensen, T. S., Nalepa, I. F., Nordsteen, B. W., Svoren, S. K., van Hall, M., Weicher, J., Wind, M. L., Zhang, D. & 8 others, Saar, Daniel, Blæsild, H., Stahlhut, M., Andersen, K. V., Dagil, Robert, Vestergaard, Bente, Ryberg, Marie L. & Kragelund, Birthe Brandt, 2023, In: The Biophysicist. 4 , 2, p. 1-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Monomeric α-synuclein activates the plasma membrane calcium pump

    Kowalski, A., Betzer, C., Larsen, S. T., Gregersen, E., Newcombe, Estella Anne, Bermejo, M. C., Bendtsen, V. W., Diemer, J., Ernstsen, C. V., Jain, S., Bou, A. E., Langkilde, Annette Eva, Nejsum, L. N., Klipp, E., Edwards, R., Kragelund, Birthe Brandt, Jensen, P. H. & Nissen, Poul, 2023, In: EMBO Journal. 42, 23, 21 p., e111122.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Protein fibrillation from another small angle—SAXS data analysis of developing systems

    Langkilde, Annette Eva & Vestergaard, Bente, 2023, Methods in Enzymology. Elsevier, Vol. 678. p. 377-409

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  6. Published

    Sex-dependent neuronal effects of α-synuclein reveal that GABAergic transmission is neuroprotective of sleep-controlling neurons

    Brito dos Santos, Altair, Thaneshwaran, S., Ali, L. K., Leguizamon, Cesar Ramon Romero, Wang, Y., Kristensen, M. P., Langkilde, Annette Eva & Kohlmeier, Kristi Anne, 2023, In: Cell & Bioscience. 13, 1, 16 p., 172.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Sex-dependent neuronal effects of α-synuclein reveal that GABAergic transmission is neuroprotective of sleep-controlling neurons

    Brito dos Santos, Altair, Thaneshwaran, S., Ali, L. K., Leguizamon, Cesar Ramon Romero, Wang, Yang, Kristensen, M. P., Langkilde, Annette Eva & Kohlmeier, Kristi Anne, 2023, Research Square-Preprint, 29 p.

    Research output: Working paper › Preprint › Research

  8. Published

    Targeting NOX2 with Bivalent Small-Molecule p47phox-p22phox Inhibitors

    Zang, J., Peters, F., Cambet, Y., Cifuentes-Pagano, E., Hissabu, M. M. S., Dustin, C. M., Svensson, L. H., Olesen, M. M., Poulsen, M. F. L., Jacobsen, Stig, Tuelung, P. S., Narayanan, Dilip, Langkilde, Annette Eva, Gajhede, Michael, Pagano, P. J., Jaquet, V., Vilhardt, Frederik & Bach, Anders, 2023, In: Journal of Medicinal Chemistry. 66, 21, p. 14963–15005

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. 2022
  10. Published

    Sleep-controlling neurons are sensitive and vulnerable to multiple forms of α-synuclein: implications for the early appearance of sleeping disorders in α-synucleinopathies

    Brito dos Santos, Altair, Skaanning, L. K., Thaneskwaran, S., Mikkelsen, E., Leguizamon, Cesar Ramon Romero, Skamris, T., Kristensen, M. P., Langkilde, Annette Eva & Kohlmeier, Kristi Anne, 9 May 2022, Research Square-Preprint, 46 p.

    Research output: Working paper › Preprint › Research

  11. Published

    Protein fibrillation from another small angle: Sample preparation and SAXS data collection

    Vestergaard, Bente & Langkilde, Annette Eva, 2022, Methods in Enzymology. Academic Press, Vol. 677. p. 291-321 (Methods in Enzymology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  12. Published

    Recommendations for addressing the translational gap between experimental and clinical research on amyloid diseases

    Solomon, M., Foderà, Vito, Langkilde, Annette Eva, Elliott, P., Tagliavini, F., Forsyth, V. T., Klementieva, O. & Bellotti, V., 2022, In: Journal of Translational Medicine. 20, 1, 7 p., 213.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Sleep-controlling neurons are sensitive and vulnerable to multiple forms of α-synuclein: implications for the early appearance of sleeping disorders in α-synucleinopathies

    Brito dos Santos, Altair, Skaanning, L. K., Thaneshwaran, S., Mikkelsen, E., Romero-Leguizamón, C. R., Skamris, T., Kristensen, M. P., Langkilde, Annette Eva & Kohlmeier, Kristi Anne, 2022, In: Cellular and Molecular Life Sciences. 79, 8, 450.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. 2021
  15. Published

    The impact of folding modes and deuteration on the atomic resolution structure of hen egg-white lysozyme

    Ramos, J., Laux, V., Haertlein, M., Forsyth, V. T., Mossou, E., Larsen, Sine & Langkilde, Annette Eva, 1 Dec 2021, In: Acta crystallographica Section D: Structural biology . 77, 12, p. 1579-1590 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Insight into Calcium-Binding Motifs of Intrinsically Disordered Proteins

    Newcombe, Estella Anne, Fernandes, Catarina, Lundsgaard, J. E., Brakti, Inna, Lindorff-Larsen, Kresten, Langkilde, Annette Eva, Skriver, Karen & Kragelund, Birthe Brandt, 2021, In: Biomolecules. 11, 8, 17 p., 1173.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Refinement of α-Synuclein Ensembles Against SAXS Data: Comparison of Force Fields and Methods

    Ahmed, M. C., Skaanning, L. K., Jussupow, A., Newcombe, Estella Anne, Kragelund, Birthe Brandt, Camilloni, C., Langkilde, Annette Eva & Lindorff-Larsen, Kresten, 2021, In: Frontiers in Molecular Biosciences. 8, 13 p., 654333.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Structural insights into protein folding, stability and activity using in vivo perdeuteration of hen egg-white lysozyme

    Ramos, J. C. M., Laux, V., Haertlein, M., Boeri Erba, E., McAuley , K., Forsyth, V. T., Mossou, E., Larsen, Sine & Langkilde, Annette Eva, 2021, In: IUCrJ. 8, 3, 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Structure and thermodynamics of transient protein-protein complexes by chemometric decomposition of SAXS datasets

    Sagar, A., Herranz-Trillo, F., Langkilde, Annette Eva, Vestergaard, Bente & Bernadó, P., 2021, In: Structure. 29, 9, p. 1074-1090

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    α-Synuclein Responses in the Laterodorsal Tegmentum, the Pedunculopontine Tegmentum and the Substantia Nigra: Implications for Early Appearance of Sleep Disorders in Parkinson’s Disease

    Brito dos Santos, Altair, Skaanning, L. K., Mikkelsen, E., Leguizamon, Cesar Ramon Romero, Kristensen, M. P., Klein, A. B., Thaneshwaran, S. S., Langkilde, Annette Eva & Kohlmeier, Kristi Anne, 2021, In: Journal of Parkinson's Disease. 11, 4, p. 1773-1790

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. 2020
  22. Published

    Size-Selective Phagocytic Clearance of Fibrillar α-Synuclein through Conformational Activation of Complement Receptor 4

    Juul-madsen, K., Qvist, P., Bendtsen, K. L., Langkilde, Annette Eva, Vestergaard, Bente, Howard, K. A., Dehesa-etxebeste, M., Paludan, S. R., Andersen, G. R., Jensen, P. H., Otzen, D. E., Romero-ramos, M. & Vorup-jensen, T., 22 Jan 2020, In: The Journal of Immunology. 204, 5, p. 1345-1361

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Avidity within the N-terminal anchor drives α-synuclein membrane interaction and insertion

    Cholak, E., Bugge, K., Khondker, A., Gauger, K., Pedraz-Cuesta, E., Pedersen, M. E., Bucciarelli, S., Vestergaard, Bente, Pedersen, Stine Helene Falsig, Rheinstädter, M. C., Langkilde, Annette Eva & Kragelund, Birthe Brandt, 2020, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 34, 6, p. 7462-7482 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Developing Inhibitors of the p47phox-p22phox Protein-Protein Interaction by Fragment-Based Drug Discovery

    Solbak, Sara Marie Øie, Zang, J., Narayanan, Dilip, Høj, L. J., Bucciarelli, S., Softley, C., Meier, S., Langkilde, Annette Eva, Gotfredsen, C. H., Sattler, M. & Bach, Anders, 2020, In: Journal of Medicinal Chemistry. 63, 3, p. 1156-1177

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    The Non-Fibrillating N-Terminal of α-Synuclein Binds and Co-Fibrillates with Heparin

    Skaanning, L. K., Santoro, A., Skamris, T., Martinsen, J. H., D’Ursi, A. M., Bucciarelli, S., Vestergaard, Bente, Bugge, K., Langkilde, Annette Eva & Kragelund, Birthe Brandt, 2020, In: Biomolecules. 10, 8, 23 p., 1192.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    The structural basis of fungal glucuronoyl esterase activity on natural substrates

    Ernst, H. A., Mosbech, C., Langkilde, Annette Eva, Westh, P., Meyer, A. S., Wittrup Agger, J. & Larsen, Sine, 2020, In: Nature Communications. 11, 1026, p. 1-12

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. 2019
  28. Published

    Distinct α-Synuclein:Lipid Co-Structure Complexes Affect Amyloid Nucleation through Fibril Mimetic Behavior

    Cholak, E., Bucciarelli, S., Bugge, K., Johansen, Nicolai Tidemand, Vestergaard, Bente, Arleth, Lise, Kragelund, Birthe Brandt & Langkilde, Annette Eva, Nov 2019, In: Biochemistry. 58, 50, p. 5052-5065

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. 2018
  30. Published

    Noninvasive Structural Analysis of Intermediate Species During Fibrillation: An Application of Small-Angle X-Ray Scattering

    Langkilde, Annette Eva, Herranz-Trillo, F., Bernadó, P. & Vestergaard, Bente, 8 Jun 2018, Amyloid Proteins: methods and protocols. Sigurdsson, E., Calero, M. & Gasset, M. (eds.). Humana Press, Vol. 1779. p. 209-239 31 p. (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  31. Published

    Femtosecond X-ray coherent diffraction of aligned amyloid fibrils on low background graphene

    Seuring, C., Ayyer, K., Filippaki, E., Barthelmess, M., Longchamp, J-N., Ringler, P., Pardini, T., Wojtas, D. H., Coleman, M. A., Dörner, K., Fuglerud, S., Hammarin, G., Habenstein, B., Langkilde, A. E., Loquet, A., Meents, A., Riek, R., Stahlberg, H., Boutet, S., Hunter, M. S. & 7 others, Koglin, J., Liang, M., Ginn, H. M., Millane, R. P., Frank, M., Barty, A. & Chapman, H. N., 9 May 2018, In: Nature Communications. 9, 1, 10 p., 1836.

    Research output: Contribution to journal › Journal article › Research › peer-review

Previous 1 2 Next

ID: 11736