Annette Eva Langkilde
Associate Professor
Structural Biology
Universitetsparken 2
2100 København Ø
- 2002
- Published
Diastereomeric salts of lactic acid and 1-phenylethylamine, their structures and relative stabilities
Langkilde, Annette Eva, Oddershede, J. & Larsen, Sine, 2002, In: Acta Crystallographica B. 58, p. 1044-1050Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
Structures of three salts of phthalic acid; variation in crystal packing and geometry of the hydrogen phthalate ion
Langkilde, Annette Eva, Madsen, D. & Larsen, Sine, 2004, In: Acta Crystallographica. B60, p. 502-511Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Facile cobalt(III) template synthesis of novel branched hexadentate polyamine monocarboxylates
Barfod, R., Eriksen, J., Golding, B. T., Hammershøi, Anders, Jacobsen, T. A., Langkilde, Annette Eva, Larsen, Sine, Mønsted, O., Sargeson, A. M. & Sørensen, H. O., 2005, In: Dalton Transactions (Print Edition). 3, p. 491-500 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
High resolution X-ray diffraction of macromolecular crystals: The challenge of obtaining accurate data and extracting valid information
Langkilde, Annette Eva, 2008, Kemisk Institut, Københavns Universitet.Research output: Book/Report › Ph.D. thesis › Research
- Published
Short strong hydrogen bonds in proteins: a case study of rhamnogalacturonan acetylesterase
Langkilde, Annette Eva, Kristensen, S. M., Lo Leggio, Leila, Mølgaard, A., Jensen, Jan Halborg, Houk, A. R., Poulsen, Jens-Christian Navarro, Larsen, Sine & Kauppinen, S., 2008, In: Acta Crystallographica. Section D: Biological Crystallography. 64, p. 851-863Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Methods for structural characterization of prefibrillar intermediates and amyloid fibrils
Langkilde, Annette Eva & Vestergaard, Bente, 2009, In: FEBS Letters. 583, 16, p. 2600-2609Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sparing the ortho-position in nucleophilic aromatic substitution-specific displacement of the 4-SePh group in 2,4-bis(phenylseleno)nitrobenzene
Stuhr-Hansen, N., Götze, T. F., Henriksen, L., Sølling, Theis Ivan, Langkilde, Annette Eva & Sørensen, H. O., 2009, In: Heteroatom Chemistry. 20, 2, p. 101-108Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
The first lesson in the classroom - getting students engaged in active learning process
Langkilde, Annette Eva, 2011, Improving University Science Teaching and Learning: Pedagogical Projects 2010. Ulriksen, L., Rump, C. & Hansen, H. W. (eds.). Department of Science Education, University of Copenhagen, Vol. 3. p. 3-17Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education
- 2012
- Published
Structural and functional insight into how the Plasmodium falciparum VAR2CSA protein mediates binding to chondroitin sulfate A in placental malaria
Clausen, Thomas Mandel, Christoffersen, S., Dahlbäck, M., Langkilde, Annette Eva, Jensen, K. E., Resende, M., Agerbæk, Mette Ørskov, Andersen, D., Berisha, B., Ditlev, S. B., Pinto, V. V., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Larsen, Sine & Salanti, Ali, 2012, In: Journal of Biological Chemistry. 287, 28, p. 23332-45 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural characterization of prefibrillar intermediates and amyloid fibrils by small-angle X-ray scattering
Langkilde, Annette Eva & Vestergaard, Bente, 2012, Amyloid proteins: methods and protocols. Sigurdsson, E. M., Calero, M. & Gasset, M. (eds.). 2 ed. New York: Springer Science+Business Media, Vol. 849. p. 137-155 18 p. (Methods in Molecular Biology, Vol. 849).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- 2013
- Published
Wildtype and A30P mutant alpha-synuclein form different fibril structures
Nielsen, S. B., Macchi, F., Raccosta , S., Langkilde, Annette Eva, Giehm, L., Kyrsting, A. H., Svane, A. S. P., Manno, M., Christiansen, G., Nielsen, N. C., Oddershede, L. B., Vestergaard, Bente & Otzen, D., 2013, In: PLOS ONE. 8, 7, e67713.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Small-Angle X-ray Scattering Screening Complements Conventional Biophysical Analysis: Comparative Structural and Biophysical Analysis of Monoclonal Antibodies IgG1, IgG2, and IgG4
Tian, X., Langkilde, Annette Eva, Thorolfsson, M., Rasmussen, H. B. & Vestergaard, Bente, Jun 2014, In: Journal of Pharmaceutical Sciences. 103, 6, p. 1701-10 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein/lipid coaggregates are formed during α-synuclein-induced disruption of lipid bilayers
van Maarschalkerweerd, A., Vetri, V., Langkilde, Annette Eva, Foderà, Vito & Vestergaard, Bente, 13 Oct 2014, In: Biomacromolecules. 15, 10, p. 3643-54 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
In-depth analysis of subclass-specific conformational preferences of IgG antibodies
Tian, X., Vestergaard, Bente, Thorolfsson, M., Yang, Z., Rasmussen, H. B. & Langkilde, Annette Eva, 1 Jan 2015, In: IUCrJ. 2, 1, p. 9-18 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The architecture of amyloid-like peptide fibrils revealed by X-ray scattering, diffraction and electron microscopy
Langkilde, Annette Eva, Morris, K. L., Serpell, L. C., Svergun, D. I. & Vestergaard, Bente, Apr 2015, In: Acta crystallographica. Section D, Biological crystallography. 71, Pt 4, p. 882-95 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formation of covalent di-tyrosine dimers in recombinant α-synuclein
van Maarschalkerweerd, A., Pedersen, M., Peterson, H., Nilsson, M., Nguyen, T., Skamris, T., Rand, Kasper Dyrberg, Vetri, V., Langkilde, Annette Eva & Vestergaard, Bente, 19 Oct 2015, In: Intrinsically Disordered Proteins. 3, 1, p. 1-12 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Monoclonal Antibodies Follow Distinct Aggregation Pathways During Production-Relevant Acidic Incubation and Neutralization
Pedersen, T. S., Tian, X., Thorolfsson, M., Karkov, H. S., Rasmussen, H. B., Langkilde, Annette Eva & Vestergaard, Bente, Mar 2016, In: Pharmaceutical Research. 33, 3, p. 716-28 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Femtosecond X-ray coherent diffraction of aligned amyloid fibrils on low background graphene
Seuring, C., Ayyer, K., Filippaki, E., Barthelmess, M., Longchamp, J-N., Ringler, P., Pardini, T., Wojtas, D. H., Coleman, M. A., Dörner, K., Fuglerud, S., Hammarin, G., Habenstein, B., Langkilde, A. E., Loquet, A., Meents, A., Riek, R., Stahlberg, H., Boutet, S., Hunter, M. S. & 7 others, , 9 May 2018, In: Nature Communications. 9, 1, 10 p., 1836.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Noninvasive Structural Analysis of Intermediate Species During Fibrillation: An Application of Small-Angle X-Ray Scattering
Langkilde, Annette Eva, Herranz-Trillo, F., Bernadó, P. & Vestergaard, Bente, 8 Jun 2018, Amyloid Proteins: methods and protocols. Sigurdsson, E., Calero, M. & Gasset, M. (eds.). Humana Press, Vol. 1779. p. 209-239 31 p. (Methods in Molecular Biology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- 2019
- Published
Distinct α-Synuclein:Lipid Co-Structure Complexes Affect Amyloid Nucleation through Fibril Mimetic Behavior
Cholak, E., Bucciarelli, S., Bugge, K., Johansen, Nicolai Tidemand, Vestergaard, Bente, Arleth, Lise, Kragelund, Birthe Brandt & Langkilde, Annette Eva, Nov 2019, In: Biochemistry. 58, 50, p. 5052-5065Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Avidity within the N-terminal anchor drives α-synuclein membrane interaction and insertion
Cholak, E., Bugge, K., Khondker, A., Gauger, K., Pedraz-Cuesta, E., Pedersen, M. E., Bucciarelli, S., Vestergaard, Bente, Pedersen, Stine Helene Falsig, Rheinstädter, M. C., Langkilde, Annette Eva & Kragelund, Birthe Brandt, 2020, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 34, 6, p. 7462-7482 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Developing Inhibitors of the p47phox-p22phox Protein-Protein Interaction by Fragment-Based Drug Discovery
Solbak, Sara Marie Øie, Zang, J., Narayanan, Dilip, Høj, L. J., Bucciarelli, S., Softley, C., Meier, S., Langkilde, Annette Eva, Gotfredsen, C. H., Sattler, M. & Bach, Anders, 2020, In: Journal of Medicinal Chemistry. 63, 3, p. 1156-1177Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Non-Fibrillating N-Terminal of α-Synuclein Binds and Co-Fibrillates with Heparin
Skaanning, L. K., Santoro, A., Skamris, T., Martinsen, J. H., D’Ursi, A. M., Bucciarelli, S., Vestergaard, Bente, Bugge, K., Langkilde, Annette Eva & Kragelund, Birthe Brandt, 2020, In: Biomolecules. 10, 8, 23 p., 1192.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The structural basis of fungal glucuronoyl esterase activity on natural substrates
Ernst, H. A., Mosbech, C., Langkilde, Annette Eva, Westh, P., Meyer, A. S., Wittrup Agger, J. & Larsen, Sine, 2020, In: Nature Communications. 11, 1026, p. 1-12Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Size-Selective Phagocytic Clearance of Fibrillar α-Synuclein through Conformational Activation of Complement Receptor 4
Juul-madsen, K., Qvist, P., Bendtsen, K. L., Langkilde, Annette Eva, Vestergaard, Bente, Howard, K. A., Dehesa-etxebeste, M., Paludan, S. R., Andersen, G. R., Jensen, P. H., Otzen, D. E., Romero-ramos, M. & Vorup-jensen, T., 22 Jan 2020, In: The Journal of Immunology. 204, 5, p. 1345-1361Research output: Contribution to journal › Journal article › Research › peer-review
ID: 11736
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Wildtype and A30P mutant alpha-synuclein form different fibril structures
Research output: Contribution to journal › Journal article › Research › peer-review
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176
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The architecture of amyloid-like peptide fibrils revealed by X-ray scattering, diffraction and electron microscopy
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
136
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Femtosecond X-ray coherent diffraction of aligned amyloid fibrils on low background graphene
Research output: Contribution to journal › Journal article › Research › peer-review
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