Annette Eva Langkilde

Annette Eva Langkilde

Associate Professor


  1. 2018
  2. Published

    Femtosecond X-ray coherent diffraction of aligned amyloid fibrils on low background graphene

    Seuring, C., Ayyer, K., Filippaki, E., Barthelmess, M., Longchamp, J-N., Ringler, P., Pardini, T., Wojtas, D. H., Coleman, M. A., Dörner, K., Fuglerud, S., Hammarin, G., Habenstein, B., Langkilde, A. E., Loquet, A., Meents, A., Riek, R., Stahlberg, H., Boutet, S., Hunter, M. S. & 7 others, Koglin, J., Liang, M., Ginn, H. M., Millane, R. P., Frank, M., Barty, A. & Chapman, H. N., 9 May 2018, In: Nature Communications. 9, 1, 10 p., 1836.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2016
  4. Published

    Monoclonal Antibodies Follow Distinct Aggregation Pathways During Production-Relevant Acidic Incubation and Neutralization

    Pedersen, T. S., Tian, X., Thorolfsson, M., Karkov, H. S., Rasmussen, H. B., Langkilde, Annette Eva & Vestergaard, Bente, Mar 2016, In: Pharmaceutical Research. 33, 3, p. 716-28 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2015
  6. Published

    Formation of covalent di-tyrosine dimers in recombinant α-synuclein

    van Maarschalkerweerd, A., Pedersen, M., Peterson, H., Nilsson, M., Nguyen, T., Skamris, T., Rand, Kasper Dyrberg, Vetri, V., Langkilde, Annette Eva & Vestergaard, Bente, 19 Oct 2015, In: Intrinsically Disordered Proteins. 3, 1, p. 1-12 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The architecture of amyloid-like peptide fibrils revealed by X-ray scattering, diffraction and electron microscopy

    Langkilde, Annette Eva, Morris, K. L., Serpell, L. C., Svergun, D. I. & Vestergaard, Bente, Apr 2015, In: Acta crystallographica. Section D, Biological crystallography. 71, Pt 4, p. 882-95 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    In-depth analysis of subclass-specific conformational preferences of IgG antibodies

    Tian, X., Vestergaard, Bente, Thorolfsson, M., Yang, Z., Rasmussen, H. B. & Langkilde, Annette Eva, 1 Jan 2015, In: IUCrJ. 2, 1, p. 9-18 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2014
  10. Published

    Protein/lipid coaggregates are formed during α-synuclein-induced disruption of lipid bilayers

    van Maarschalkerweerd, A., Vetri, V., Langkilde, Annette Eva, Foderà, Vito & Vestergaard, Bente, 13 Oct 2014, In: Biomacromolecules. 15, 10, p. 3643-54 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Small-Angle X-ray Scattering Screening Complements Conventional Biophysical Analysis: Comparative Structural and Biophysical Analysis of Monoclonal Antibodies IgG1, IgG2, and IgG4

    Tian, X., Langkilde, Annette Eva, Thorolfsson, M., Rasmussen, H. B. & Vestergaard, Bente, Jun 2014, In: Journal of Pharmaceutical Sciences. 103, 6, p. 1701-10 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2013
  13. Published

    Wildtype and A30P mutant alpha-synuclein form different fibril structures

    Nielsen, S. B., Macchi, F., Raccosta , S., Langkilde, Annette Eva, Giehm, L., Kyrsting, A. H., Svane, A. S. P., Manno, M., Christiansen, G., Nielsen, N. C., Oddershede, L. B., Vestergaard, Bente & Otzen, D., 2013, In: PLOS ONE. 8, 7, e67713.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2012
  15. Published

    Structural and functional insight into how the Plasmodium falciparum VAR2CSA protein mediates binding to chondroitin sulfate A in placental malaria

    Clausen, Thomas Mandel, Christoffersen, S., Dahlbäck, M., Langkilde, Annette Eva, Jensen, K. E., Resende, M., Agerbæk, Mette Ørskov, Andersen, D., Berisha, B., Ditlev, S. B., Pinto, V. V., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Larsen, Sine & Salanti, Ali, 2012, In: Journal of Biological Chemistry. 287, 28, p. 23332-45 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Structural characterization of prefibrillar intermediates and amyloid fibrils by small-angle X-ray scattering

    Langkilde, Annette Eva & Vestergaard, Bente, 2012, Amyloid proteins: methods and protocols. Sigurdsson, E. M., Calero, M. & Gasset, M. (eds.). 2 ed. New York: Springer Science+Business Media, Vol. 849. p. 137-155 18 p. (Methods in Molecular Biology, Vol. 849).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  17. 2011
  18. Published

    The first lesson in the classroom - getting students engaged in active learning process

    Langkilde, Annette Eva, 2011, Improving University Science Teaching and Learning: Pedagogical Projects 2010. Ulriksen, L., Rump, C. & Hansen, H. W. (eds.). Department of Science Education, University of Copenhagen, Vol. 3. p. 3-17

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  19. 2009
  20. Published

    Methods for structural characterization of prefibrillar intermediates and amyloid fibrils

    Langkilde, Annette Eva & Vestergaard, Bente, 2009, In: FEBS Letters. 583, 16, p. 2600-2609

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Sparing the ortho-position in nucleophilic aromatic substitution-specific displacement of the 4-SePh group in 2,4-bis(phenylseleno)nitrobenzene

    Stuhr-Hansen, N., Götze, T. F., Henriksen, L., Sølling, Theis Ivan, Langkilde, Annette Eva & Sørensen, H. O., 2009, In: Heteroatom Chemistry. 20, 2, p. 101-108

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2008
  23. Published

    High resolution X-ray diffraction of macromolecular crystals: The challenge of obtaining accurate data and extracting valid information

    Langkilde, Annette Eva, 2008, Kemisk Institut, Københavns Universitet.

    Research output: Book/ReportPh.D. thesisResearch

  24. Published

    Short strong hydrogen bonds in proteins: a case study of rhamnogalacturonan acetylesterase

    Langkilde, Annette Eva, Kristensen, S. M., Lo Leggio, Leila, Mølgaard, A., Jensen, Jan Halborg, Houk, A. R., Poulsen, Jens-Christian Navarro, Larsen, Sine & Kauppinen, S., 2008, In: Acta Crystallographica. Section D: Biological Crystallography. 64, p. 851-863

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. 2005
  26. Published

    Facile cobalt(III) template synthesis of novel branched hexadentate polyamine monocarboxylates

    Barfod, R., Eriksen, J., Golding, B. T., Hammershøi, Anders, Jacobsen, T. A., Langkilde, Annette Eva, Larsen, Sine, Mønsted, O., Sargeson, A. M. & Sørensen, H. O., 2005, In: Dalton Transactions (Print Edition). 3, p. 491-500 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2004
  28. Published

    Structures of three salts of phthalic acid; variation in crystal packing and geometry of the hydrogen phthalate ion

    Langkilde, Annette Eva, Madsen, D. & Larsen, Sine, 2004, In: Acta Crystallographica. B60, p. 502-511

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. 2002
  30. Published

    Diastereomeric salts of lactic acid and 1-phenylethylamine, their structures and relative stabilities

    Langkilde, Annette Eva, Oddershede, J. & Larsen, Sine, 2002, In: Acta Crystallographica B. 58, p. 1044-1050

    Research output: Contribution to journalJournal articleResearchpeer-review

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