Blanca Aldana

Blanca Aldana

Associate Professor

ORCID: 0000-0002-5027-1218

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  1. Published

    Preserved blood-brain barrier and neurovascular coupling in female 5xFAD model of Alzheimer's disease

    Zhukov, Oleg, He, Chen, Soylu-Kucharz, R., Cai, Changsi, Lauritzen, Andreas, Aldana, Blanca, Björkqvist, M., Lauritzen, Martin & Kucharz, Krzysztof, 2023, In: Frontiers in Aging Neuroscience. 15, 18 p., 1089005.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Patient iPSC-derived neurons for disease modeling of frontotemporal dementia with mutation in CHMP2B

    Zhang, Y., Schmid, B., Qas Younan, N. K., Rasmussen, M. A., Garcia, B. I. A., Agger, M., Callø, K., Stummann, T. C., Larsen, H. M., Nielsen, T. T., Huang, J., Xu, F., Liu, X., Bolund, L., Meyer, M., Bak, L. K., Waagepetersen, H. S., Luo, Y., Nielsen, J. E., Consortium, T. FRA. & 4 others, Holst, B., Clausen, C., Hyttel, P. & Freude, Kristine, 2017, In: Stem Cell Reports. 8, 3, p. 648-658

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Divergent Cellular Energetics, Glutamate Metabolism, and Mitochondrial Function Between Human and Mouse Cerebral Cortex

    Westi, Emil Winther, Jakobsen, Emil, Voss, C. M., Bak, Lasse Kristoffer, Pinborg, Lars Hageman, Aldana, Blanca & Andersen, J. V., 2022, In: Molecular Neurobiology. 59, p. 7495–7512

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Using stable isotope tracing to unravel the metabolic components of neurodegeneration: Focus on neuron-glia metabolic interactions

    Westi, Emil Winther, Andersen, Jens Velde & Aldana, Blanca, 2023, In: Neurobiology of Disease. 182, 12 p., 106145.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Glutamate homeostasis revisited - neuronal transport and metabolism

    Waagepetersen, Helle S., McNair, Laura M., Christensen, S. K., Andersen, Jens Velde & Aldana, Blanca, 2019, p. 19-19.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  6. Published

    Essential Roles of Lactate in Müller Cell Survival and Function

    Vohra, Rupali, Aldana, Blanca, Jensen, Dorte Skytt, Freude, Kristine, Waagepetersen, Helle S., Bergersen, L. H. & Kolko, Miriam, 1 Dec 2018, In: Molecular Neurobiology. 55, 12, p. 9108-9121 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Prevention of Cell Death by Activation of Hydroxycarboxylic Acid Receptor 1 (GPR81) in Retinal Explants

    Vohra, Rupali, Sanz-Morello, B., Tams, A. L. M., Mouhammad, Zaynab Ahmad, Freude, Kristine, Hannibal, Jens, Aldana, Blanca, Bergersen, L. H. & Kolko, Miriam, 2022, In: Cells. 11, 13, 2098.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Muller cell survival and function is maintained by the presence of lactate

    Vohra, Rupali, Skytt, D. M., Aldana, Blanca, Freude, Kristine, Waagepetersen, Helle S., Bergersen, L. H. & Kolko, Miriam, Jul 2018, p. 1480. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  9. Published

    Lactate-Mediated Protection of Retinal Ganglion Cells

    Vohra, Rupali, Aldana, Blanca, Bulli, G., Jensen, Dorte Skytt, Waagepetersen, Helle S., Bergersen, L. H. & Kolko, Miriam, 19 Apr 2019, In: Journal of Molecular Biology. 431, 9, p. 1878-1888 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Dual Properties of Lactate in Müller Cells: The Effect of GPR81 Activation

    Vohra, Rupali, Aldana, Blanca, Waagepetersen, Helle S., Bergersen, L. H. & Kolko, Miriam, 1 Mar 2019, In: Investigative Ophthalmology & Visual Science. 60, 4, p. 999-1008 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Lactate: More than merely a metabolic waste product

    Vohra, Rupali, Aldana, Blanca, Skytt, D. M., Waagepetersen, Helle S., Bergersen, L. H. & Kolko, Miriam, 2018, In: Acta Ophthalmologica. 96, Supplement 261, p. 137 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  12. Published

    Decreased Glucose Metabolism and Glutamine Synthesis in the Retina of a Transgenic Mouse Model of Alzheimer's Disease

    Tams, A. L. M., Sanz-Morello, B., Westi, Emil Winther, Mouhammad, Zaynab Ahmad, Andersen, Jens Velde, Freude, Kristine, Vohra, Rupali, Hannibal, Jens, Aldana, Blanca & Kolko, Miriam, 2022, In: Cellular and Molecular Neurobiology. 42, 1, p. 291–303

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Role of S1P and RhoA/Rho-kinase pathways in age-related myogenic tone deficiency in mouse small mesenteric and cerebral arteries

    Skovsted, G. F., Aupetit, A., Björling , K., Haanes, K. A., Syberg, S., Jørgensen, N. R., Aldana, Blanca, Freude, Kristine, Pearson, J. T. & Jensen, Lars Jørn, 2 Jul 2024.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  14. Published

    Integrative Characterization of the R6/2 Mouse Model of Huntington's Disease Reveals Dysfunctional Astrocyte Metabolism

    Skotte, Niels Henning, Andersen, Jens Velde, Santos, A., Aldana, Blanca, Willert, C. W., Nørremølle, Anne, Waagepetersen, Helle S. & Nielsen, Michael Lund, 2018, In: Cell Reports. 23, 7, p. 2211-2224 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The antidepressant sertraline prevents the behavioral and EEG changes induced in two animal models of seizures

    Sitges, M., Aldana, Blanca, Gómez, C. D. & Nekrassov, V., Dec 2012, In: Epilepsy and Behavior. 25, 4, p. 511-516 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Sertraline reduces IL-1β and TNF-α mRNA expression and overcomes their rise induced by seizures in the rat hippocampus

    Sitges, M., Gómez, C. D. & Aldana, Blanca, 3 Nov 2014, In: PLoS ONE. 9, 11, e111665.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Characterization of phenytoin, carbamazepine, vinpocetine and clorgyline simultaneous effects on sodium channels and catecholamine metabolism in rat striatal nerve endings

    Sitges, M., Aldana, Blanca, Chiu, L. M. & Nekrassov, V., Mar 2009, In: Neurochemical Research. 34, 3, p. 470-479 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Effect of the Anti-depressant Sertraline, the Novel Anti-seizure Drug Vinpocetine and Several Conventional Antiepileptic Drugs on the Epileptiform EEG Activity Induced by 4-Aminopyridine

    Sitges, M., Aldana, Blanca & Reed, R. C., 1 Jun 2016, In: Neurochemical Research. 41, 6, p. 1365-1374 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Vinpocetine inhibits glutamate release induced by the convulsive agent 4-aminopyridine more potently than several antiepileptic drugs

    Sitges, M., Sanchez-Tafolla, B. M., Chiu, L. M., Aldana, Blanca & Guarneros, A., Oct 2011, In: Epilepsy Research. 96, 3, p. 257-266 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Amino acids: Glutamate dehydrogenase: An anaplerotic enzyme in neurons and an energy producing enzyme in astrocytes

    Schousboe, Arne & Aldana, Blanca, 29 Jul 2021, Encyclopedia of Biological Chemistry: Third Edition. Elsevier, Vol. 1. p. 51-55 5 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  21. Published

    Generation of a set of isogenic, gene-edited iPSC lines homozygous for all main APOE variants and an APOE knock-out line

    Schmid, B., Prehn, K. R., Nimsanor, N., Aldana, Blanca, Poulsen, U., Jorring, I., Rasmussen, M. A., Clausen, C., Mau-Holzmann, U. A., Ramakrishna, S., Muddashetty, R., Steeg, R., Bruce, K., Mackintosh, P., Ebneth, A., Holst, B. & Cabrera-Socorro, A., 2019, In: Stem Cell Research. 34, 6 p., 101349.

    Research output: Contribution to journal › Editorial › Research › peer-review

  22. Published

    Complex IV subunit isoform COX6A2 protects fast-spiking interneurons from oxidative stress and supports their function

    Sanz-Morello, B., Pfisterer, U., Hansen, Nikolaj Winther, Demharter, S., Thakur, A., Fujii, K., Levitskii, S. A., Montalant, A., Korshunova, Irina, Mammen, P. P., Kamenski, P., Noguchi, S., Aldana, Blanca, Hougaard, Karin Sørig, Perrier, Jean-Francois Marie & Khodosevich, Konstantin, 2020, In: The EMBO Journal. 39, 18, p. 1-21 e105759.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Downregulation of GABA Transporter 3 (GAT3) is Associated with Deficient Oxidative GABA Metabolism in Human Induced Pluripotent Stem Cell-Derived Astrocytes in Alzheimer's Disease

    Salcedo, C., Wagner, A., Andersen, Jens Velde, Vinten, K. T., Waagepetersen, Helle S., Schousboe, Arne, Freude, Kristine & Aldana, Blanca, 2021, In: Neurochemical Research. 46, p. 2676–2686

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Functional Metabolic Mapping Reveals Highly Active Branched-Chain Amino Acid Metabolism in Human Astrocytes, Which Is Impaired in iPSC-Derived Astrocytes in Alzheimer's Disease

    Salcedo, C., Andersen, Jens Velde, Vinten, K. T., Pinborg, Lars Hageman, Waagepetersen, Helle S., Freude, Kristine & Aldana, Blanca, 2021, In: Frontiers in Aging Neuroscience. 13, 736580.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. E-pub ahead of print

    Increased glucose metabolism and impaired glutamate transport in human astrocytes are potential early triggers of abnormal extracellular glutamate accumulation in hiPSC-derived models of Alzheimer's disease

    Salcedo, C., Pozo Garcia, V., Garcia-Adan, B., Ameen, Aisha, Gegelashvili, G., Waagepetersen, Helle S., Freude, Kristine & Aldana, Blanca, 2024, (E-pub ahead of print) In: Journal of Neurochemistry.

    Research output: Contribution to journal › Journal article › Research › peer-review

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