Céline Galvagnion-Büll
Associate Professor
Molecular and Cellular Pharmacology
Jagtvej 160
2100 København Ø
Introductory remarks on publicationslist
H-index: 22
Number of citations (without self citations): 3,008
Source: web of science
An engineered monomer binding-protein for α-synuclein efficiently inhibits the proliferation of amyloid fibrils
Agerschou, E. D., Flagmeier, P., Saridaki, T., Galvagnion-Büll, Céline, Komnig, D., Heid, L., Prasad, V., Shaykhalishahi, H., Willbold, D., Dobson, C. M., Voigt, A., Falkenbürger, B., Hoyer, W. & Buell, A. K., 7 Aug 2019, (E-pub ahead of print) In: eLife. 8Research output: Contribution to journal › Journal article › Research › peer-review
- Published
N-Terminal Acetylation of alpha-Synuclein Slows down Its Aggregation Process and Alters the Morphology of the Resulting Aggregates
Bell, R., Thrush, R. J., Castellana-Cruz, M., Oeller, M., Staats, R., Nene, A., Flagmeier, P., Xu, C. K., Satapathy, S., Galvagnion-Büll, Céline, Wilson, M. R., Dobson, C. M., Kumita, J. R. & Vendruscolo, M., 2022, In: Biochemistry. 61, 17, p. 1743–1756Research output: Contribution to journal › Journal article › Research › peer-review
Kinetic barriers to α-synuclein protofilament formation and conversion into mature fibrils
Brown, J. W. P., Meisl, G., Knowles, T. P. J., Buell, A. K., Dobson, C. M. & Galvagnion-Büll, Céline, 10 Jul 2018, In: Chemical communications (Cambridge, England). 54, 56, p. 7854-7857 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
β-Synuclein suppresses both the initiation and amplification steps of α-synuclein aggregation via competitive binding to surfaces
Brown, J. W. P., Buell, A. K., Michaels, T. C. T., Meisl, G., Carozza, J., Flagmeier, P., Vendruscolo, M., Knowles, T. P. J., Dobson, C. M. & Galvagnion-Büll, Céline, 3 Nov 2016, In: Scientific Reports. 6, p. 36010Research output: Contribution to journal › Journal article › Research › peer-review
Solution conditions determine the relative importance of nucleation and growth processes in alpha-synuclein aggregation
Buell, A. K., Galvagnion-Büll, Céline, Gaspar, R., Sparr, E., Vendruscolo, M., Knowles, T. P. J., Linse, S. & Dobson, C. M., 27 May 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 21, p. 7671-7676Research output: Contribution to journal › Journal article › Research › peer-review
Discovery of a small-molecule binder of the oncoprotein gankyrin that modulates gankyrin activity in the cell
Chattopadhyay, A., O'Connor, C. J., Zhang, F., Galvagnion-Büll, Céline, Galloway, W. R. J. D., Tan, Y. S., Stokes, J. E., Rahman, T., Verma, C., Spring, D. R. & Itzhaki, L. S., 5 Apr 2016, In: Scientific Reports. 6Research output: Contribution to journal › Journal article › Research › peer-review
Mutations associated with familial Parkinson's disease alter the initiation and amplification steps of alpha-synuclein aggregation
Flagmeier, P., Meisl, G., Vendruscolo, M., Knowles, T. P. J., Dobson, C. M., Buell, A. K. & Galvagnion-Büll, Céline, 13 Sep 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 37, p. 10328-10333Research output: Contribution to journal › Journal article › Research › peer-review
The Role of Lipids Interacting with α-Synuclein in the Pathogenesis of Parkinson's Disease.
Galvagnion-Büll, Céline, 2017, In: Journal of Parkinson's Disease. 7, 3, p. 433-450Research output: Contribution to journal › Journal article › Research › peer-review
Production and initial structural characterization of the TM4TM5 helix-loop-helix domain of the translocator protein
Galvagnion-Büll, Céline, Montaville, P., Coic, Y. -. & Jamin, N., Feb 2013, In: Journal of Peptide Science. 19, 2, p. 102-109Research output: Contribution to journal › Journal article › Research › peer-review
Fundamental mechanisms of amyloid fibers by the formation of a-synuclein protein in Parkinson's disease quantitative Modeling
Galvagnion-Büll, Céline & Buell, A. K., 2015, In: Medecine Sciences. 31, 6-7, p. 597-600Research output: Contribution to journal › Comment/debate › Research › peer-review
Lipid vesicles trigger alpha-synuclein aggregation by stimulating primary nucleation
Galvagnion-Büll, Céline, Buell, A. K., Meisl, G., Michaels, T. C. T., Vendruscolo, M., Knowles, T. P. J. & Dobson, C. M., Mar 2015, In: Nature Chemical Biology. 11, 3, p. 229-U101Research output: Contribution to journal › Journal article › Research › peer-review
Chemical properties of lipids strongly affect the kinetics of the membrane-induced aggregation of alpha-synuclein
Galvagnion-Büll, Céline, Brown, J. W. P., Ouberai, M. M., Flagmeier, P., Vendruscolo, M., Buell, A. K., Sparr, E. & Dobson, C. M., 28 Jun 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 26, p. 7065-7070Research output: Contribution to journal › Journal article › Research › peer-review
Folding and Association of Thermophilic Dimeric and Trimeric DsrEFH Proteins: Tm0979 and Mth1491
Galvagnion-Büll, Céline, Smith, M. T. J., Broom, A., Vassall, K. A., Meglei, G., Gaspar, J. A., Stathopulos, P. B., Cheyne, B. & Meiering, E. M., 7 Apr 2009, In: Biochemistry. 48, 13, p. 2891-2906Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sphingolipid changes in Parkinson L444P GBA mutation fibroblasts promote α-synuclein aggregation
Galvagnion-Büll, Céline, Marlet, Frederik Ravnkilde, Cerri, S., Schapira, A. H. V., Blandini, F. & Di Monte, D. A., 2022, In: Brain. 145, 3, p. 1038-1051Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural characterisation of α-synuclein-membrane interactions and the resulting aggregation using small angle scattering
Galvagnion-Büll, Céline, Barclay, A., Makasewicz, K., Marlet, Frederik Ravnkilde, Moulin, M., Devos, J. M., Linse, S., Martel, A., Porcar, L., Sparr, E., Pedersen, Martin Cramer, Roosen-Runge, F., Arleth, Lise & Buell, A. K., 2024, In: Physical chemistry chemical physics : PCCP. 26, p. 10998-11013Research output: Contribution to journal › Journal article › Research › peer-review
Lipid Dynamics and Phase Transition within α-Synuclein Amyloid Fibrils
Galvagnion-Büll, Céline, Topgaard, D., Makasewicz, K., Buell, A. K., Linse, S., Sparr, E. & Dobson, C. M., 19 Dec 2019, In: The Journal of Physical Chemistry Letters. 10, 24, p. 7872-7877 6 p.Research output: Contribution to journal › Letter › Research › peer-review
Microfluidic Diffusion Platform for Characterizing the Sizes of Lipid Vesicles and the Thermodynamics of Protein-Lipid Interactions
Gang, H., Galvagnion-Büll, Céline, Meisl, G., Müller, T., Pfammatter, M., Buell, A. K., Levin, A., Dobson, C. M., Mu, B. & Knowles, T. P. J., 6 Mar 2018, In: Analytical Chemistry. 90, 5, p. 3284-3290 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
The inverted free energy landscape of an intrinsically disordered peptide by simulations and experiments
Granata, D., Baftizadeh, F., Habchi, J., Galvagnion-Büll, Céline, De Simone, A., Camilloni, C., Laio, A. & Vendruscolo, M., 26 Oct 2015, In: Scientific Reports. 5Research output: Contribution to journal › Journal article › Research › peer-review
Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes
Habchi, J., Chia, S., Galvagnion-Büll, Céline, Michaels, T. C. T., Bellaiche, M. M. J., Ruggeri, F. S., Sanguanini, M., Idini, I., Kumita, J. R., Sparr, E., Linse, S., Dobson, C. M., Knowles, T. P. J. & Vendruscolo, M., Jun 2018, In: Nature Chemistry. 10, 6, p. 673-683 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Ostwald's rule of stages governs structural transitions and morphology of dipeptide supramolecular polymers
Levin, A., Mason, T. O., Adler-Abramovich, L., Buell, A. K., Meisl, G., Galvagnion-Büll, Céline, Bram, Y., Stratford, S. A., Dobson, C. M., Knowles, T. P. J. & Gazit, E., Nov 2014, In: Nature Communications. 5Research output: Contribution to journal › Journal article › Research › peer-review
alpha-Synuclein Senses Lipid Packing Defects and Induces Lateral Expansion of Lipids Leading to Membrane Remodeling
Ouberai, M. M., Wang, J., Swann, M. J., Galvagnion-Büll, Céline, Guilliams, T., Dobson, C. M. & Welland, M. E., 19 Jul 2013Research output: Other contribution › Research
Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine
Perni, M., Flagmeier, P., Limbocker, R., Cascella, R., Aprile, F. A., Galvagnion, C., Heller, G. T., Meisl, G., Chen, S. W., Kumita, J. R., Challa, P. K., Kirkegaard, J. B., Cohen, S. I. A., Mannini, B., Barbut, D., Nollen, E. A. A., Cecchi, C., Cremades, N., Knowles, T. P. J., Chiti, F. & 3 others, , 17 Aug 2018, In: ACS chemical biology. 13, 8, p. 2308-2319 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity
Perni, M., Galvagnion, C., Maltsev, A., Meisl, G., Müller, M. B. D., Challa, P. K., Kirkegaard, J. B., Flagmeier, P., Cohen, S. I. A., Cascella, R., Chen, S. W., Limbocker, R., Sormanni, P., Heller, G. T., Aprile, F. A., Cremades, N., Cecchi, C., Chiti, F., Nollen, E. A. A., Knowles, T. P. J. & 4 others, , 7 Feb 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 6, p. E1009-E1017Research output: Contribution to journal › Journal article › Research › peer-review
Direct Observation of Heterogeneous Amyloid Fibril Growth Kinetics via Two-Color Super-Resolution Microscopy
Pinotsi, D., Buell, A. K., Galvagnion-Büll, Céline, Dobson, C. M., Schierle, G. S. K. & Kaminski, C. F., Jan 2014, In: Nano Letters. 14, 1, p. 339-345Research output: Contribution to journal › Journal article › Research › peer-review
Conformational stability and folding mechanisms of dimeric proteins
Rumfeldt, J. A. O., Galvagnion-Büll, Céline, Vassall, K. A. & Meiering, E. M., Sep 2008, In: Progress in Biophysics & Molecular Biology. 98, 1, p. 61-84Research output: Contribution to journal › Review › Research › peer-review
- Published
The interplay between Glucocerebrosidase, α-synuclein and lipids in human models of Parkinson's disease
Sanz Muñoz, S., Petersen, D., Marlet, Frederik Ravnkilde, Kücükköse, E. & Galvagnion-Büll, Céline, 2021, In: Biophysical Chemistry. 273, 106534.Research output: Contribution to journal › Review › Research › peer-review
- Published
Capillary flow experiments for thermodynamic and kinetic characterization of protein liquid-liquid phase separation
Stender, E. G. P., Ray, S., Norrild, R. K., Larsen, J. A., Petersen, D., Farzadfard, A., Galvagnion-Büll, Céline, Jensen, H. & Buell, A. K., 2021, In: Nature Communications. 12, 1, 18 p., 7289.Research output: Contribution to journal › Journal article › Research › peer-review
Targeting the Intrinsically Disordered Structural Ensemble of alpha-Synuclein by Small Molecules as a Potential Therapeutic Strategy for Parkinson's Disease
Toth, G., Gardai, S. J., Zago, W., Bertoncini, C. W., Cremades, N., Roy, S. L., Tambe, M. A., Rochet, J-C., Galvagnion, C., Skibinski, G., Finkbeiner, S., Bova, M., Regnstrom, K., Chiou, S-S., Johnston, J., Callaway, K., Anderson, J. P., Jobling, M. F., Buell, A. K., Yednock, T. A. & 6 others, , 14 Feb 2014, In: PLOS ONE. 9, 2Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Editorial: Amyloid-Membrane Interactions in Protein Misfolding Disorders: From Basic Mechanisms to Therapy
Vassallo, N., Galvagnion-Büll, Céline & Chi, E. Y., 2022, In: Frontiers in Cell and Developmental Biology. 10, 870791.Research output: Contribution to journal › Editorial › Research › peer-review
C-terminal truncation of α-synuclein promotes amyloid fibril amplification at physiological pH
van der Wateren, I. M., Knowles, T. P. J., Buell, A. K., Dobson, C. M. & Galvagnion-Büll, Céline, 7 Jul 2018, In: Chemical Science. 9, 25, p. 5506-5516 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 215668004
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Kinetic barriers to α-synuclein protofilament formation and conversion into mature fibrils
Research output: Contribution to journal › Journal article › Research › peer-review
-
126
downloads
The interplay between Glucocerebrosidase, α-synuclein and lipids in human models of Parkinson's disease
Research output: Contribution to journal › Review › Research › peer-review
Published -
115
downloads
Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes
Research output: Contribution to journal › Journal article › Research › peer-review