Christian Adam Olsen

Christian Adam Olsen

Professor

ORCID: 0000-0002-2953-8942

Publication year:
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1 - 25 out of 112Page size: 25
  1. 2024
  2. Published

    Contemporary Applications of Thioamides and Methods for their Synthesis

    Hansen, T. N. & Olsen, Christian Adam, 2024, In: Chemistry: A European Journal. 30, 9, e202303770.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2023
  4. Published

    Förster Resonance Energy Transfer Assay for Investigating the Reactivity of Thioesters in Biochemistry and Native Chemical Ligation

    Gless, B. H., Schmied, S. H., Bejder, Benjamin Svejdal & Olsen, Christian Adam, 2023, In: JACS Au. 3, 5, p. 1443–1451

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Substrates and Cyclic Peptide Inhibitors of the Oligonucleotide-Activated Sirtuin 7**

    Bolding, J. E., Nielsen, A. L., Jensen, Iben, Hansen, T. N., Ryberg, Line Abildgaard, Jameson, S. T., Harris, Pernille, Peters, G. H. J., Denu, J. M., Rogers, Joseph Matthew & Olsen, Christian Adam, 2023, In: Angewandte Chemie - International Edition. 62, 49, e202314597.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. 2022
  7. Published

    Aryl Fluorosulfate Based Inhibitors That Covalently Target the SIRT5 Lysine Deacylase**

    Bolding, J. E., Martín-Gago, P., Rajabi, N., Gamon, Luke Francis, Hansen, T. N., Bartling, Christian Reinhard Otto, Strømgaard, Kristian, Davies, Michael J. & Olsen, Christian Adam, 2022, In: Angewandte Chemie - International Edition. 61, 47, 11 p., e202204565.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Chiral Posttranslational Modification to Lysine ε-Amino Groups

    Moreno Yruela, Carlos, Baek, M., Monda, F. & Olsen, Christian Adam, 2022, In: Accounts of Chemical Research. 55, 10, p. 1456-1466

    Research output: Contribution to journal › Review › Research › peer-review

  9. Published

    Class I histone deacetylases (HDAC1-3) are histone lysine delactylases

    Moreno Yruela, Carlos, Zhang, D., Wei, W., Bæk, M., Liu, W., Gao, J., Danková, D., Nielsen, A. L., Bolding, J. E., Yang, L., Jameson, S. T., Wong, J., Olsen, Christian Adam & Zhao, Y., 2022, In: Science Advances. 8, 3, eabi6696.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Determination of Slow-Binding HDAC Inhibitor Potency and Subclass Selectivity

    Moreno Yruela, Carlos & Olsen, Christian Adam, 2022, In: ACS Medicinal Chemistry Letters. 13, 5, p. 779-785

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Investigation of Carboxylic Acid Isosteres and Prodrugs for Inhibition of the Human SIRT5 Lysine Deacylase Enzyme**

    Rajabi, N., Hansen, T. N., Nielsen, A. L., Nguyen, H. T., Bæk, M., Bolding, J. E., Bahlke, O., Petersen, S. E. G., Bartling, Christian Reinhard Otto, Strømgaard, Kristian & Olsen, Christian Adam, 2022, In: Angewandte Chemie - International Edition. 61, 22, 9 p., e202115805.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    On-Resin Peptide Cyclization Using the 3-Amino-4-(Methylamino)Benzoic Acid MeDbz Linker

    Gless, B. H. & Olsen, Christian Adam, 2022, Methods in Molecular Biology. Humana Press, p. 101-115 (Methods in Molecular Biology, Vol. 2371).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  13. 2021
  14. Published

    Hydroxamic acid-modified peptide microarrays for profiling isozyme-selective interactions and inhibition of histone deacetylases

    Moreno Yruela, Carlos, Bæk, M., Vrsanova, A., Schulte, C., Maric, H. M. & Olsen, Christian Adam, 4 Jan 2021, In: Nature Communications. 12, 1

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    High-throughput screening of histone deacetylases and determination of kinetic parameters using fluorogenic assays

    Moreno Yruela, Carlos & Olsen, Christian Adam, 2021, In: STAR Protocols. 2, 1, 14 p., 100313.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Mechanism-based inhibitors of SIRT2: structure–activity relationship, X-ray structures, target engagement, regulation of α-tubulin acetylation and inhibition of breast cancer cell migration

    Nielsen, A. L., Rajabi, N., Kudo, N., Jørgensen, Kathrine Lundø, Moreno Yruela, Carlos, Bæk, M., Fontenas, M., Lucidi, A., Madsen, A. S., Yoshida, M. & Olsen, Christian Adam, 2021, In: RSC Chemical Biology. 2, p. 612-626

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Mitochondria-targeted inhibitors of the human SIRT3 lysine deacetylase

    Troelsen, K. S., Bæk, M., Nielsen, A. L., Madsen, A. S., Rajabi, N. & Olsen, Christian Adam, 2021, In: RSC Chemical Biology. 2, p. 627-635

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Rearrangement of Thiodepsipeptides by S → N Acyl Shift Delivers Homodetic Autoinducing Peptides

    Gless, B. H., Bejder, Benjamin Svejdal, Monda, F., Bojer, Martin Saxtorph, Ingmer, Hanne & Olsen, Christian Adam, 2021, In: Journal of the American Chemical Society. 143, 28, p. 10514–10518

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    SIRT5 Is a Druggable Metabolic Vulnerability in Acute Myeloid Leukemia

    Yan, D., Franzini, A., Pomicter, A. D., Halverson, B. J., Antelope, O., Mason, C. C., Ahmann, J. M., Senina, A. V., Vellore, N. A., Jones, C. L., Zabriskie, M. S., Than, H., Xiao, M. J., van Scoyk, A., Patel, A. B., Clair, P. M., Heaton, W. L., Owen, S. C., Andersen, J. L., Egbert, C. M. & 11 others, Reisz, J. A., D'Alessandro, A., Cox, J. E., Gantz, K. C., Redwine, H. M., Iyer, S. M., Khorashad, J. S., Rajabi, N., Olsen, Christian Adam, O'Hare, T. & Deininger, M. W., 2021, In: Cancer Discovery. 2, 3, p. 266-287

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  20. Published

    The Chemical Biology-Medicinal Chemistry Continuum: EFMC's Vision

    Duca, M., Gillingham, D., Olsen, Christian Adam, Sbardella, G., Skaanderup, P. R., van der Stelt, M., Vauzeilles, B., Vazquez, O. & Auberson, Y. P., 2021, In: ChemBioChem. 22, 19, p. 2823-2825

    Research output: Contribution to journal › Editorial › Research › peer-review

  21. Published

    Zn2+-Dependent Histone Deacetylases in Plants: Structure and Evolution

    Yruela, I., Moreno Yruela, Carlos & Olsen, Christian Adam, 2021, In: Trends in Plant Science. 26, 7, p. 741-757

    Research output: Contribution to journal › Review › Research › peer-review

  22. 2020
  23. Published

    Photo Cross-Linking Probes Containing ϵ-N-Thioacyllysine and ϵ-N-Acyl-(δ-aza)lysine Residues

    Bæk, M., Martín-Gago, P., Laursen, J. S., Madsen, J. L. H., Chakladar, S. & Olsen, Christian Adam, 23 Mar 2020, In: Chemistry - A European Journal. 26, 17, p. 3862-3869 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Finding the gas pedal on a slow sirtuin

    Nielsen, A. L. & Olsen, Christian Adam, 31 Jan 2020, In: Journal of Biological Chemistry. 295, p. 400-401

    Research output: Contribution to journal › Literature review › Research › peer-review

  25. Published

    Dethioacylation by sirtuins 1–3: Considerations for drug design using mechanism-based sirtuin inhibition

    Rajabi, N., Nielsen, A. L. & Olsen, Christian Adam, 2020, In: A C S Medicinal Chemistry Letters. 11, 10, p. 1886-1892

    Research output: Contribution to journal › Letter › Research › peer-review

  26. Published

    Hydroxamic Acid-Containing Peptides in the Study of Histone Deacetylases

    Moreno Yruela, Carlos & Olsen, Christian Adam, 2020, Topics in Medicinal Chemistry. A. M. (ed.). Springer, p. 29-54 26 p. (Topics in Medicinal Chemistry, Vol. 33).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  27. Published

    Increasing the Functional Group Diversity in Helical beta-Peptoids: Achievement of Solvent- and pH-Dependent Folding

    Wellhofer, I., Beck, J., Frydenvang, Karla Andrea, Brase, S. & Olsen, Christian Adam, 2020, In: Journal of Organic Chemistry. 85, 16, p. 10466-10478 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Peptide Inhibitors of the α-Cobratoxin-Nicotinic Acetylcholine Receptor Interaction

    Lynagh, T., Kiontke, S., Meyhoff-Madsen, M., Gless, B. H., Johannesen, J., Kattelmann, S., Christiansen, A., Dufva, M., Laustsen, A. H., Devkota, K., Olsen, Christian Adam, Kuemmel, D., Pless, Stephan & Lohse, B., 2020, In: Journal of Medicinal Chemistry. 63, 22, p. 13709-13718 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Selective inhibitors of SIRT2 regulate perinuclear α-tubulin acetylation, migration, and invasion of breast cancer cells

    Nielsen, A. L., Rajabi, N., Kudo, N., Jørgensen, Kathrine Lundø, Fontenas, M., Lucidi, A., Madsen, A. S., Yoshida, M. & Olsen, Christian Adam, 2020, In: bioRxiv. 26 p.

    Research output: Contribution to journal › Journal article › Research

  30. 2019
  31. Published

    Kinetic Tuning of HDAC Inhibitors Affords Potent Inducers of Progranulin Expression

    Moreno Yruela, Carlos, Fass, D. M., Cheng, C., Herz, J., Olsen, Christian Adam & Haggarty, S. J., 22 Jul 2019, In: A C S Chemical Neuroscience. 10, 8, p. 3769-3777

    Research output: Contribution to journal › Journal article › Research › peer-review

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