Christian Adam Olsen

Christian Adam Olsen

Professor

ORCID: 0000-0002-2953-8942

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  1. Published

    Metabolic control by sirtuins and other enzymes that sense NAD(+), NADH, or their ratio

    Anderson, K. A., Madsen, A. S., Olsen, Christian Adam & Hirschey, M. D., Dec 2017, In: B B A - Reviews on Cancer. 1858, 12, p. 991-998 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  2. Published

    SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion

    Anderson, K. A., Huynh, F. K., Fisher-Wellman, K., Stuart, J. D., Peterson, B. S., Douros, J. D., Wagner, G. R., Thompson, J. W., Madsen, A. S., Green, M. F., Sivley, R. M., Ilkayeva, O. R., Stevens, R. D., Backos, D. S., Capra, J. A., Olsen, Christian Adam, Campbell, J. E., Muoio, D. M., Grimsrud, P. A. & Hirschey, M. D., 4 Apr 2017, In: Cell Metabolism. 25, 4, p. 838-855.e15

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Guanidino groups greatly enhance the action of antimicrobial peptidomimetics against bacterial cytoplasmic membranes

    Andreev, K., Bianchi, C., Laursen, J. S., Citterio, L., Hein-Kristensen, L., Gram, L., Kuzmenko, I., Olsen, Christian Adam & Gidalevitz, D., 2014, In: B B A - Biomembranes. 1838, 10, p. 2492-502 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    The agr inhibitors solonamide B and analogues alter immune responses to Staphylococccus aureus but do not exhibit adverse effects on immune cell functions

    Baldry, M., Kitir, B., Frøkiær, Hanne, Christensen, S. B., Taverne, N., Meijerink, M., Franzyk, Henrik, Olsen, Christian Adam, Wells, J. M. & Ingmer, Hanne, 2016, In: P L o S One. 11, 1, 17 p., e0145618.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Aryl Fluorosulfate Based Inhibitors That Covalently Target the SIRT5 Lysine Deacylase**

    Bolding, J. E., Martín-Gago, P., Rajabi, N., Gamon, Luke Francis, Hansen, T. N., Bartling, Christian Reinhard Otto, Strømgaard, Kristian, Davies, Michael J. & Olsen, Christian Adam, 2022, In: Angewandte Chemie - International Edition. 61, 47, 11 p., e202204565.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Substrates and Cyclic Peptide Inhibitors of the Oligonucleotide-Activated Sirtuin 7**

    Bolding, J. E., Nielsen, A. L., Jensen, Iben, Hansen, T. N., Ryberg, Line Abildgaard, Jameson, S. T., Harris, Pernille, Peters, G. H. J., Denu, J. M., Rogers, Joseph Matthew & Olsen, Christian Adam, 2023, In: Angewandte Chemie - International Edition. 62, 49, e202314597.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Photo Cross-Linking Probes Containing ϵ-N-Thioacyllysine and ϵ-N-Acyl-(δ-aza)lysine Residues

    Bæk, M., Martín-Gago, P., Laursen, J. S., Madsen, J. L. H., Chakladar, S. & Olsen, Christian Adam, 23 Mar 2020, In: Chemistry - A European Journal. 26, 17, p. 3862-3869 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Cross-Talk between Staphylococcus aureus and Other Staphylococcal Species via the agr Quorum Sensing System

    Canovas de la Nuez, J., Baldry, M., Bojer, Martin Saxtorph, Andersen, P. S., Grzeskowiak, P. K., Stegger, M., Damborg, Peter Panduro, Olsen, Christian Adam & Ingmer, Hanne, 2016, In: Frontiers in Microbiology. 7, 1733.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    The Chemical Biology-Medicinal Chemistry Continuum: EFMC's Vision

    Duca, M., Gillingham, D., Olsen, Christian Adam, Sbardella, G., Skaanderup, P. R., van der Stelt, M., Vauzeilles, B., Vazquez, O. & Auberson, Y. P., 2021, In: ChemBioChem. 22, 19, p. 2823-2825

    Research output: Contribution to journal › Editorial › Research › peer-review

  10. Published

    Effects of Thionation and Fluorination on Cis-Trans Isomerization in Tertiary Amides: An Investigation of N-Alkylglycine (Peptoid) Rotamers

    Engel-Andreasen, J., Wich, K., Laursen, J. S., Harris, P. & Olsen, Christian Adam, 4 Mar 2015, In: Journal of Organic Chemistry. 80, 11, p. 5415–5427 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Backbone-Fluorinated 1,2,3-Triazole-Containing Dipeptide Surrogates

    Engel-Andreasen, J., Wellhöfer, I., Wich, K. & Olsen, Christian Adam, 16 Oct 2017, In: Journal of Organic Chemistry. 82, 21, p. 11613-11619

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Cellular uptake and membrane-destabilising properties of a-peptide/ß-peptoid chimeras: lessons for the design of new cell-penetrating peptides

    Foged, Camilla, Franzyk, Henrik, Bahrami, S., Frøkjær, Sven, Jaroszewski, J. W., Nielsen, Hanne Mørck & Olsen, Christian Adam, 2008, In: BBA General Subjects. 1778, 11, p. 2487-2495

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Scalable and Purification-Free Synthesis of a Myristoylated Fluorogenic Sirtuin Substrate

    Galleano, I., Nielsen, J., Stahl Madsen, A. & Olsen, Christian Adam, 2017, In: SYNLETT: Accounts and Rapid Communications in Chemical Synthesis. 28, 16, p. 2169-2173

    Research output: Contribution to journal › Letter › Research › peer-review

  14. Published

    A Continuous, Fluorogenic Sirtuin 2 Deacylase Assay: Substrate Screening and Inhibitor Evaluation

    Galleano, I., Schiedel, M., Jung, M., Madsen, A. S. & Olsen, Christian Adam, 11 Feb 2016, In: Journal of Medicinal Chemistry. 59, 3, p. 1021-31 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    On-Resin Peptide Cyclization Using the 3-Amino-4-(Methylamino)Benzoic Acid MeDbz Linker

    Gless, B. H. & Olsen, Christian Adam, 2022, Methods in Molecular Biology. Humana Press, p. 101-115 (Methods in Molecular Biology, Vol. 2371).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  16. Published

    Rearrangement of Thiodepsipeptides by S → N Acyl Shift Delivers Homodetic Autoinducing Peptides

    Gless, B. H., Bejder, Benjamin Svejdal, Monda, F., Bojer, Martin Saxtorph, Ingmer, Hanne & Olsen, Christian Adam, 2021, In: Journal of the American Chemical Society. 143, 28, p. 10514–10518

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Förster Resonance Energy Transfer Assay for Investigating the Reactivity of Thioesters in Biochemistry and Native Chemical Ligation

    Gless, B. H., Schmied, S. H., Bejder, Benjamin Svejdal & Olsen, Christian Adam, 2023, In: JACS Au. 3, 5, p. 1443–1451

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Direct Peptide Cyclization and One-Pot Modification Using the MeDbz Linker

    Gless, B. H. & Olsen, Christian Adam, 6 Aug 2018, In: Journal of Organic Chemistry. 83, 17, p. 10525-10534

    Research output: Contribution to journal › Letter › Research › peer-review

  19. Published

    Structure-activity relationship study based on Autoinducing Peptide (AIP) from dog pathogen S. schleiferi

    Gless, B. H., Peng, P., Pedersen, K. D., Gotfredsen, C. H., Ingmer, Hanne & Olsen, Christian Adam, 2017, In: Organic Letters. 19, 19, p. 5276–5279

    Research output: Contribution to journal › Letter › Research › peer-review

  20. Published

    Identification of autoinducing thiodepsipeptides from staphylococci enabled by native chemical ligation

    Gless, B. H., Bojer, Martin Saxtorph, Peng, P., Baldry, M., Ingmer, Hanne & Olsen, Christian Adam, 22 Apr 2019, In: Nature Chemistry. 11, p. 463–469

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Synthesis and antiangiogenic activity of N-alkylated levamisole derivatives

    Hansen, A. N., Bendiksen, C. D., Sylvest, L., Friis, T., Stærk, Dan, Jørgensen, Flemming Steen, Olsen, Christian Adam & Houen, G., 2012, In: P L o S One. 7, 9, 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Accepted/In press

    Sulfur(VI) Fluoride Exchange Chemistry in Solid-Phase Synthesis of Compound Arrays: Discovery of Histone Deacetylase Inhibitors

    Hansen, T. N., Danková, D., Bæk, M., Grlaš, L. & Olsen, Christian Adam, 2024, (Accepted/In press) In: JACS Au.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Contemporary Applications of Thioamides and Methods for their Synthesis

    Hansen, T. N. & Olsen, Christian Adam, 2024, In: Chemistry: A European Journal. 30, 9, e202303770.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Probing the Bioactive Conformation of an Archetypal Natural Product HDAC Inhibitor with Conformationally Homogeneous Triazole-Modified Cyclic Tetrapeptides

    Horne, W. S., Olsen, Christian Adam, Beierle, J. M., Montero, A. & Ghadiri, M. R., 2009, In: Angewandte Chemie International Edition. 48, 26, p. 4718-4724

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Potential Agents for Treating Cystic Fibrosis: Cyclic Tetrapeptides That Restore Trafficking and Activity of Delta F508-CFTR

    Hutt, D. M., Olsen, Christian Adam, Vickers, C. J., Herman, D., Chalfant, M. A., Montero, A., Leman, L. J., Burkle, R., Maryanoff, B. E., Balch, W. E. & Ghadiri, M. R., Sep 2011, In: ACS Medicinal Chemistry Letters. 2, 9, p. 703-707

    Research output: Contribution to journal › Journal article › Research › peer-review

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