Dan Stærk

Dan Stærk

Head of Department, Visiting professor

ORCID: 0000-0003-0074-298X

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  1. Published

    Structure elucidation and absolute configuration determination of nortriterpenoids from Picramnia glazioviana

    Gimenes, L., Luna-Dulcey, L., Batista Junior, J. M., dos Santos Junior, F. M., Popolin, C. P., Cominetti, M. R., Fernandes, J. B. & Stærk, Dan, 2020, In: Journal of Natural Products. 83, p. 1859-1876

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Coupling of a high-resolution monoamine oxidase-A inhibitor assay and HPLC-SPE-NMR for advanced bioactivity-profiling of plant extracts

    Grosso, C., Jäger, A. & Stærk, Dan, 2013, In: Phytochemical Analysis. 24, 2, p. 141-147

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Synthesis and antiangiogenic activity of N-alkylated levamisole derivatives

    Hansen, A. N., Bendiksen, C. D., Sylvest, L., Friis, T., Stærk, Dan, Jørgensen, Flemming Steen, Olsen, Christian Adam & Houen, G., 2012, In: P L o S One. 7, 9, 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Tripterygium wilfordii cytochrome P450s catalyze the methyl shift and epoxidations in the biosynthesis of triptonide

    Hansen, N. L., Kjaerulff, Louise, Heck, Q. K., Forman, Victor, Stærk, Dan, Møller, Birger Lindberg & Andersen-Ranberg, Johan, 2022, In: Nature Communications. 13, 5011.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Integrating pathway elucidation with yeast engineering to produce polpunonic acid the precursor of the anti-obesity agent celastrol

    Hansen, N. L., Miettinen, Karel, Zhao, Yong, Ignea, C., Andreadeli, A., Raadam, Morten Hessellund, Makris, A. M., Møller, Birger Lindberg, Stærk, Dan, Bak, Søren & Kampranis, Sotirios, 2020, In: Microbial Cell Factories. 19, 17 p., 15.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Secondary metabolite comparison of the species within the Heterobasidion annosum s.l. complex

    Hansson, D., Wubshet, S. G., Olson, Å., Karlsson, M., Stærk, Dan & Broberg, A., 2014, In: Phytochemistry. 108, p. 243-251 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Semi-synthesis of novel buprenorphine derivatives and their anti-nociceptive properties and dependency potential

    Hasanpour, Z., Salehi, P., Bunch, Lennart, Khoramjouy, M., Bararjanian, M., Stærk, Dan & Faizi, M., 2021, In: Canadian Journal of Chemistry. 99, 11, p. 910-919

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Semi-synthesis of novel thebaine derivatives with low cytotoxicity and their antibacterial and antihemolytic properties

    Hasanpour, Z., Salehi, P., Aliahmadi, A., Hoseinpour, M., Behboodi, H., Stærk, Dan & Bararjanian, M., 2023, In: Medicinal Chemistry Research. 32, p. 1713–1725

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Biosynthesis of bioactive diterpenoids in the medicinal plant Vitex agnus-castus

    Heskes, A., Sundram, T. C. M., Boughton, B. A., Bjerg Jensen, N., Hansen, N. L., Crocoll, C., Cozzi, F., Rasmussen, Simon, Hamberger, B., Hamberger, B. R., Stærk, Dan, Møller, Birger Lindberg & Pateraki, Irini, 2018, In: Plant Journal. 93, p. 943-958 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Expedient solution-phase synthesis and NMR studies of arylopeptoids

    Hjelmgaard, T., Faure, S., Stærk, Dan, Taillefumier, C. & Nielsen, J., 2011, In: European Journal of Organic Chemistry. 2011, 22, p. 4121-4132 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Efficient and versatile COMU-mediated solid-phase submonomer synthesis of arylopeptoids (oligomeric N-substituted aminomethyl benzamides)

    Hjelmgaard, T., Faure, S., Stærk, Dan, Taillefumier, C. & Nielsen, J., 2011, In: Organic & Biomolecular Chemistry. 9, p. 6832-6843 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Improved solid-phase synthesis and study of arylopeptoids with conformation-directing side chains

    Hjelmgaard, T., Faure, S., De Santis, E., Stærk, Dan, Alexander, B. D., Edwards, A. A., Taillefumier, C. & Nielsen, J., 2012, In: Tetrahedron. 68, 23, p. 4444-4454 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Recreational drug use at a major music festival: trend analysis of anonymised pooled urine

    Hoegberg, L., Christiansen, C., Søe, J. L., Telving, R., Andreasen, M. F., Stærk, Dan, Christrup, Lona Louring & Kongstad, Kenneth Thermann, 2018, In: Clinical Toxicology. 56, p. 245-255 1360496.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    4-Benzyloxylonchocarpin and muracatanes A-C from Ranunculus muricatus L. and their biological effects

    Hussain, H., Ali, I., Wang, D., Mamadalieva, N. Z., Hussain, W., Csuk, R., Loesche, A., Fischer, L., Stærk, Dan, Anam, S., AlZain, M. N., Mushtaq, M., Ul-Haq, Z., Ullah, R., Noman, O. M., Abbas, G. & Green, I. R., 2020, In: Biomolecules. 10, 11, 15 p., 1562.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Expanding the terpene biosynthetic code with non-canonical 16 carbon atom building blocks

    Ignea, C., Raadam, Morten Hessellund, Koutsaviti, A., Zhao, Yong, Duan, Yaotao, Harizani, M., Miettinen, Karel, Georgantea, P., Rosenfeldt, M., Viejo-Ledesma, S. E., Petersen, Mikael Agerlin, Bredie, Wender, Stærk, Dan, Roussis, V., Ioannou, E. & Kampranis, Sotirios, 2022, In: Nature Communications. 13, 16 p., 5188.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Characterization of antileishmanial compounds from Lawsonia inermis leaves using semi-high resolution antileishmanial profiling combined with HPLC-HRMS-SPE-NMR

    Iqbal, K., Iqbal, J., Stærk, Dan & Kongstad, Kenneth Thermann, 2017, In: Frontiers in Pharmacology. 8, 7 p., 337.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Detection of Seasonal Variation in Aloe Polysaccharides Using Carbohydrate Detecting Microarrays

    Isager Ahl, Louise, Al-Husseini, N., Al-Helle, S., Stærk, Dan, Grace, O. M., Willats, W. G. T., Mravec, Jozef, Jørgensen, Bodil & Rønsted, Nina, 2019, In: Frontiers in Plant Science. 10, p. 1-14 512.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Naravelia zeyanica: occurrence of primary benzamides in flowering plants

    Jaroszewski, J. W., Stærk, Dan, Holm-Møller, S. B., Jensen, T. H. & Franzyk, Henrik, 2005, In: Natural Product Research. 19, 3, p. 291-294

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Erratum: "Naravelia zeylanica: Occurrence of primary benzamides in flowering plants" (Natural Product Research vol. 19 (3) (291-294))

    Jaroszewski, J. W., Stærk, Dan, Holm-Møller, S. B., Jensen, T. H., Franzyk, Henrik & Somanadhan, B., 1 Jun 2005, In: Natural Product Research. 19, 4, 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  20. Published

    Lægemidler fra naturstoffer: fortid eller fremtid?

    Jaroszewski, J. W., Christensen, Søren Brøgger, Franzyk, Henrik, Stærk, Dan & Ziegler, H., 2008, In: Lægemiddelforskning. p. 4-6

    Research output: Contribution to journal › Journal article › Communication

  21. Published

    Characterization of a membrane-bound C-glucosyltransferase responsible for carminic acid biosynthesis in Dactylopius coccus Costa

    Kannangara, R. M., Siukstaite, L., Borch-Jensen, J., Madsen, B., Kongstad, Kenneth Thermann, Stærk, Dan, Bennedsen, M., Okkels, F. T., Rasmussen, S. A., Larsen, T. O., Frandsen, R. J. N. & Møller, Birger Lindberg, 2017, In: Nature Communications. 8, 12 p., 1987.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    HPLC-SPE-NMR identification of a novel metabolite containing the benzo[c]oxepin skeleton from the endophytic fungus Pestalotiopsis virgatula culture

    Kesting, J. R., Stærk, Dan, Tejesvi, M. V., Kini, K. R., Prakash, H. S. & Jaroszewski, J. W., 2009, In: Planta Medica. 75, 10, p. 1104-1106 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Production of unusual dispiro metabolites in Pestalotiopsis virgatula endophyte cultures: HPLC-SPE-NMR, electronic circular dichroism, and time-dependent density-functional computation study

    Kesting, J. R., Olsen, L., Stærk, Dan, Tejesvi, M. V., Kini, K. R., Prakash, H. S. & Jaroszewski, J. W., 26 Sep 2011, In: Journal of Natural Products. 74, 10, p. 2206-2215

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Piperidine and tetrahydropyridine alkaloids from Lobelia siphilitica and Hippobroma longiflora:

    Kesting, J. R., Tolderlund, I., Pedersen, A. F., Witt, M., Jaroszewski, J. W. & Stærk, Dan, 2009, In: Journal of Natural Products. 72, 2, p. 312-315 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    A 5-deoxyflavonol derivative in Mimosa pudica

    Kirk, L. F., Møller, M. V., Christensen, J., Stærk, Dan, Ekpe, P. & Jaroszewski, J. W., 2003, In: Biochemical Systematics and Ecology. 31, 1, p. 103-105

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Isolation, structure elucidation and PTP1B inhibitory activity of serrulatane diterpenoids from the roots of Myoporum insulare

    Kjaerulff, Louise, Jensen, A. B. J., Ndi, C., Semple, S. J., Møller, Birger Lindberg & Stærk, Dan, 2020, In: Phytochemistry Letters. 39, p. 49-56

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Accelerating drug lead discovery from nature by high-resolution bioactivity profiling combined with HPLC-HRMS-SPE-NMR

    Kongstad, Kenneth Thermann, Nyberg, N. T., Wubshet, S. G. & Stærk, Dan, Dec 2016, In: Planta Medica. 81, S 01

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  28. Published

    HPLC-HRMS-SPE-NMR combined with high resolution in vitro screening for natural fungicides

    Kongstad, Kenneth Thermann, Wubshet, S. G., Kjellerup, L., Winther, A. & Stærk, Dan, Dec 2016, In: Planta Medica. 82, S 01

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  29. Published

    High-resolution screening combined with HPLC–HRMS–SPE–NMR for identification of fungal plasma membrane H+-ATPase inhibitors from plants

    Kongstad, Kenneth Thermann, Wubshet, S. G., Johannesen, A., Kjellerup, L., winther, A. L., Jäger, A. & Stærk, Dan, 2014, In: Journal of Agricultural and Food Chemistry. 62, 24, p. 5595-5602 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Simultaneous quantification of high-dose naloxone and naloxone-3-β-D-glucuronide in human plasma by UHPLC-MS/MS

    Kongstad, Kenneth Thermann, Papathanasiou, T., Springborg, A., Lund, Trine Meldgaard, Werner, M. U. & Stærk, Dan, 2019, In: Bioanalysis. 11, 03, p. 165-173

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Fungal plasma membrane H+-ATPase inhibitory activity of o-hydroxybenzylated flavanones and chalcones from Uvaria chamae P. Beauv

    Kongstad, Kenneth Thermann, Wubshet, S. G., Kjellerup, L., winther, A. L. & Stærk, Dan, 20 Jun 2015, In: Fitoterapia. 105, p. 102-106 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Combined use of high-resolution α-glucosidase inhibition profiling and HPLC-HRMS-SPE-NMR for investigation of antidiabetic principles in crude plant extracts

    Kongstad, Kenneth Thermann, Özdemir, C., Barzak, A., Wubshet, S. G. & Stærk, Dan, 5 Feb 2015, In: Journal of Agricultural and Food Chemistry. 63, 8, p. 2257-2263 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    HPLC-SPE-NMR for combinatorial biosynthetic investigations – expanding the landscape of diterpene structural diversity

    Kongstad, Kenneth Thermann, Andersen-Ranberg, Johan, Hamberger, B. R. & Stærk, Dan, 2016. 1 p.

    Research output: Contribution to conference › Poster › Research

  34. Published

    Investigation of the mechanism and chemistry underlying Staphylococcus aureus' ability to inhibit Pseudomonas aeruginosa growth in vitro

    Kvich, Lasse Andersson, Crone, S. G., Christensen, M. H., Lima, R. D. C. L., Alhede, M., Alhede, M., Stærk, Dan & Bjarnsholt, Thomas, 2022, In: Journal of Bacteriology. 204, 11, 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Identification of natural products using HPLC-SPE combined with CapNMR

    Lambert, M., Wolfender, J., Stærk, Dan, Christensen, Søren Brøgger, Hostettmann, K. & Jaroszewski, J. W., 2007, In: Analytical Chemistry. 79, 2, p. 727-735

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    HPLC-SPE-NMR hyphenation in natural products research: optimization of analysis of Croton membranaceus extract

    Lambert, M., Stærk, Dan, Hansen, S. H. & Jaroszewski, J. W., 2005, In: Magnetic Resonance in Chemistry. 43, p. 771-775

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Rapid extract dereplication using HPLC-SPE-NMR: analysis of isoflavonoids from Smirnowia iranica

    Lambert, M., Stærk, Dan, Hansen, S. H., Sairafianpour, M. & Jaroszewski, J. W., 2005, In: Journal of Natural Products. 68, p. 1500-1509

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    High-resolution α-glucosidase inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of anti-diabetic compounds in Eremanthus crotonoides (Asteraceae)

    Lana e Silva, E., Felipe Revoredo Lobo, J., Vinther, J. M., Moreira Borges, R. & Stærk, Dan, 2016, In: Molecules. 21, 6, 19 p., 782.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Identification of reaction products between drug substances and excipients by HPLC-SPE-NMR: Ester and amide formation between citric acid and 5-aminosalicylic acid

    Larsen, J. T., Stærk, Dan, Cornett, Claus, Hansen, S. H. & Jaroszewski, J. W., 2009, In: Journal of Pharmaceutical and Biomedical Analysis. 49, p. 839-842

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Application of rotated PCA models to facilitate interpretation of metabolite profiles: commercial preparations of St. John's wort

    Lawaetz, A. J., Schmidt, B., Stærk, Dan, Jaroszewski, J. W. & Bro, Rasmus, 2009, In: Planta Medica. 75, 3, p. 271-279 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Application of Rotated PCA Models to Facilitate Interpretation of Metabolite Profiles: Commercial Preparations of St. John's Wort

    Lawaetz, A. J., Schmidt, B., Stærk, Dan, Jaroszewski, J. W. & Bro, Rasmus, 2009, In: Planta Medica.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Food preference and performance of the larvae of a specialist herbivore: variation among and within host-plant populations

    Leimu, R., Riipi, M. & Stærk, Dan, 2005, In: Acta Oecologica. 28, p. 325-330

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Identification of α-glucosidase inhibitors in Machilus litseifolia by combined use of high-resolution α-glucosidase inhibition profiling and HPLC-PDA-HRMS-SPE-NMR

    Li, T., Kongstad, Kenneth Thermann & Stærk, Dan, 2019, In: Journal of Natural Products. 82, p. 249-258

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Structure elucidation of prenyl- and geranyl substituted coumarins in Gerbera piloselloides by NMR spectroscopy, electronic circular dichroism calculations, and single crystal X-ray crystallography

    Li, T., Ma, X., Fedotov, D., Kjaerulff, Louise, Frydenvang, Karla Andrea, Coriani, S., Hansen, Paul Robert, Kongstad, Kenneth Thermann & Stærk, Dan, 8 Apr 2020, In: Molecules. 25, 25 p., 1706.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Potential of Myrtus communis Linn. as a bifunctional food: Dual high-resolution PTP1B and α-glucosidase inhibition profiling combined with HPLC-HRMS and NMR for identification of antidiabetic triterpenoids and phloroglucinol derivatives

    Liang, Chao, Stærk, Dan & Kongstad, Kenneth Thermann, 2020, In: Journal of Functional Foods. 64, 10 p., 103623.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Dual high-resolution α-glucosidase and PTP1B profiling combined with HPLC-PDA-HRMS-SPE-NMR analysis for the identification of potentially antidiabetic chromene meroterpenoids in Rhododendron capitatum

    Liang, Chao, Kjaerulff, Louise, Hansen, Paul Robert, Kongstad, Kenneth Thermann & Stærk, Dan, 2021, In: Journal of Natural Products. 84, p. 2454-2467

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Eremane, viscidane and isozizaene diterpenoids from the leaves of Eremophila rigida and their absolute configurations

    Liang, Chao, Ndi, C., Semple, S., Buirchell, B., Coriani, S., Møller, Birger Lindberg & Stærk, Dan, 2024, In: Phytochemistry. 219, 16 p., 113972.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Characterization of serrulatane diterpenoids in Eremophila phyllopoda subsp. phyllopoda by triple high-resolution α-glucosidase/PTP1B/radical scavenging profiling, NMR spectroscopy, DFT-GIAO NMR, and electronic circular dichroism calculations

    Liang, Chao, Ndi, C., Kjaerulff, Louise, Semple, S., Buirchell, B., Coriani, S., Møller, Birger Lindberg & Stærk, Dan, 2023, In: Journal of Natural Products. 86, 4, p. 694–709

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Characterization of antidiabetic serrulatane diterpenoids from Eremophila phyllopoda by triple high-resolution α-glucosidase / PTP1B / radical scavenging profiling

    Liang, Chao, Ndi, C., Semple, S., Coriani, S., Møller, Birger Lindberg & Stærk, Dan, 2021. 1 p.

    Research output: Contribution to conference › Poster › Research

  50. Published

    Identification of new PTP1B-inhibiting decipiene diterpenoid esters from Eremophila clarkei by high-resolution PTP1B inhibition profiling, enzyme kinetics analysis, and molecular docking

    Liang, Chao, Zang, J., Ndi, C., Semple, S., Buirchell, B., Coriani, S., Møller, Birger Lindberg & Stærk, Dan, 2023, In: Bioorganic Chemistry. 139, 15 p., 106744.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 1299056