Dan Stærk
Head of Department, Visiting professor
Administration and Operations
Jagtvej 160
2100 København Ø
Biopharmaceuticals
Jagtvej 162
2100 København Ø
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2(5H)-Furanone sesquiterpenes from Eremophila bignoniiflora: High-resolution inhibition profiling and PTP1B inhibitory activity
Zhao, Yong, Kjaerulff, Louise, Kongstad, Kenneth Thermann, Heskes, A. M., Møller, Birger Lindberg & Stærk, Dan, 2019, In: Phytochemistry. 166, p. 1-8 112054.Research output: Contribution to journal › Journal article › Research › peer-review
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4-Benzyloxylonchocarpin and muracatanes A-C from Ranunculus muricatus L. and their biological effects
Hussain, H., Ali, I., Wang, D., Mamadalieva, N. Z., Hussain, W., Csuk, R., Loesche, A., Fischer, L., Stærk, Dan, Anam, S., AlZain, M. N., Mushtaq, M., Ul-Haq, Z., Ullah, R., Noman, O. M., Abbas, G. & Green, I. R., 2020, In: Biomolecules. 10, 11, 15 p., 1562.Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro Plasmodium falciparum drug sensitivity assay: inhibition of parasite growth by incorporation of stomatocytogenic amphiphiles into the erythrocyte membrane
Ziegler, H. L., Stærk, Dan, Christensen, J., Hviid, Lars, Hägerstrand, H. & Jaroszewski, J. W., 2002, In: Antimicrobial Agents and Chemotherapy. 46, 5, p. 1441-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Naravelia zeyanica: occurrence of primary benzamides in flowering plants
Jaroszewski, J. W., Stærk, Dan, Holm-Møller, S. B., Jensen, T. H. & Franzyk, Henrik, 2005, In: Natural Product Research. 19, 3, p. 291-294Research output: Contribution to journal › Journal article › Research › peer-review
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Tripterygium wilfordii cytochrome P450s catalyze the methyl shift and epoxidations in the biosynthesis of triptonide
Hansen, N. L., Kjaerulff, Louise, Heck, Q. K., Forman, Victor, Stærk, Dan, Møller, Birger Lindberg & Andersen-Ranberg, Johan, 2022, In: Nature Communications. 13, 5011.Research output: Contribution to journal › Journal article › Research › peer-review
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19F-substituted amino acids as an alternative to fluorophore labels: monitoring of degradation and cellular uptake of analogues of penetratin by 19F NMR
Christensen, M. V., Kongstad, Kenneth Thermann, Sondergaard, T. E., Stærk, Dan, Nielsen, Hanne Mørck, Franzyk, Henrik & Wimmer, R., 2019, In: Journal of Biomolecular N M R. 73, p. 167-182Research output: Contribution to journal › Journal article › Research › peer-review
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1H NMR-based metabolomics applied to study of complex pharmaceutical extracts of Ginkgo biloba
Agnolet, S., Jaroszewski, J. W. & Stærk, Dan, 2009.Research output: Contribution to conference › Conference abstract for conference › Research
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1H NMR-based metabolomics combined with HPLC-PDA-MS-SPE-NMR for investigation of standardized Ginkgo biloba preparations
Agnolet, S., Jaroszewski, J. W., Verpoorte, R. & Stærk, Dan, 2010, In: Metabolomics. 6, 2, p. 292-302 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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1H-NMR based metabolomics applied to standardized Ginkgo biloba preparations
Agnolet, S., Jaroszewski, J. W., Verpoorte, R. & Stærk, Dan, 2009.Research output: Contribution to conference › Conference abstract for conference › Research
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1H-NMR based metabolomics applied to standardized Ginkgo biloba preparations
Agnolet, S., Jaroszewski, J. W., Verpoorte, R. & Stærk, Dan, 2009.Research output: Contribution to conference › Conference abstract for conference › Research
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4N-alkyloxycarbonyl derivatives of cytosine: physicochemical characterisation, and cytosine regeneration rates and release from alginic acid gels
Petersson, K. P., Pedersen, B. T., Stærk, Dan, Krogfelt, K. A. & Larsen, C. S., 2004, In: European Journal of Pharmaceutical Sciences. 23, 4-5, p. 337-345Research output: Contribution to journal › Journal article › Research › peer-review
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A 5-deoxyflavonol derivative in Mimosa pudica
Kirk, L. F., Møller, M. V., Christensen, J., Stærk, Dan, Ekpe, P. & Jaroszewski, J. W., 2003, In: Biochemical Systematics and Ecology. 31, 1, p. 103-105Research output: Contribution to journal › Journal article › Research › peer-review
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A GPCR-based yeast biosensor for biomedical, biotechnological, and point-of-use cannabinoid determination
Miettinen, Karel, Leelahakorn, Nattawat, Almeida Robles, A. R., Zhao, Yong, Hansen, L. R., Nikolajsen, I. E., Andersen, Jens Bo, Givskov, Michael, Stærk, Dan, Bak, Søren & Kampranis, Sotirios, 2022, In: Nature Communications. 13, 16 p., 3664.Research output: Contribution to journal › Journal article › Research › peer-review
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A gene cluster in Ginkgo biloba encodes unique multifunctional cytochrome P450s that initiate ginkgolide biosynthesis
Forman, Victor, Luo, Dan, Geu-Flores, Fernando, Lemcke, René, Nelson, D., Kampranis, Sotirios, Stærk, Dan, Møller, Birger Lindberg & Pateraki, Irini, 2022, In: Nature Communications. 13, 14 p., 5143.Research output: Contribution to journal › Journal article › Research › peer-review
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A new class of spermidine-derived alkaloids
Stærk, Dan, Witt, M., Oketch-Rabah, H. A. & Jaroszewski, J. W., 2003, In: Organic Letters. 5, p. 2793-2796Research output: Contribution to journal › Journal article › Research › peer-review
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A systematic review of possible interactions for herbal medicines and dietary supplements used concomitantly with disease-modifying or symptom-alleviating multiple sclerosis drugs
Petersen, M. J., Bergien, Sofie Olsgaard & Stærk, Dan, 2021, In: Phytotherapy Research. 35, 7, p. 3610-3631Research output: Contribution to journal › Journal article › Research › peer-review
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Accelerated dereplication of crude extracts using HPLC-PDA-MS-SPE-NMR
Stærk, Dan, Kesting, J. R., Sairafianpour, M., Witt, M., Asili, J., Emami, S. A. & Jaroszewski, J. W., 2009, In: Phytochemistry. 70, 8, p. 1055-1061 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Accelerating drug lead discovery from nature by high-resolution bioactivity profiling combined with HPLC-HRMS-SPE-NMR
Kongstad, Kenneth Thermann, Nyberg, N. T., Wubshet, S. G. & Stærk, Dan, Dec 2016, In: Planta Medica. 81, S 01Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Advancing HPLC-PDA-HRMS-SPE-NMR analysis of coumarins in Coleonema album by use of orthogonal reversed-phase C18 and pentafluorophenyl separations
Lima, R. D. C. L., Gramsbergen, S., Van Staden, J., Jäger, A. K., Kongstad, Kenneth Thermann & Stærk, Dan, 2017, In: Journal of Natural Products. 80, 4, p. 1020-1027Research output: Contribution to journal › Journal article › Research › peer-review
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African plants for inhibition of necrotic enzymes from snake venom
Schmidt, M. M., Nielsen, L., Søgaard, S., Stærk, Dan, Rønsted, Nina, Diallo, D., Kusamba Zacharie, C., Van Staden, J. & Jäger, A. K., 2014.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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An independent evolutionary origin for insect deterrent cucurbitacins in Iberis amara
Dong, L., Almeida Robles, A. R., Pollier, J., Khakimov, Bekzod, Bassard, J. A., Miettinen, K., Stærk, Dan, Mehran, R., Olsen, C. E., Motawie, Mohammed Saddik, Goossens, A. & Bak, Søren, 2021, In: Molecular Biology and Evolution. 38, 11, p. 4659-4673 15 p., msab213.Research output: Contribution to journal › Journal article › Research › peer-review
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An inverse association between plasma benzoxazinoid metabolites and PSA after rye intake in men with prostate cancer revealed with a new method
Nordin, E., Steffensen, S. K., Laursen, B. B., Andersson, S., Johansson, J., Åman, P., Hallmans, G., Borre, M., Stærk, Dan, Hanhineva, K., Fomsgaard, I. S. & Landberg, R., 2022, In: Scientific Reports. 12, 14 p., 5260.Research output: Contribution to journal › Journal article › Research › peer-review
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Analogues of the natural product Sinefungin as inhibitors of EHMT1 and EHMT2
Devkota, K., Lohse, B., Liu, Q., Wang, M., Stærk, Dan, Berthelsen, J. & Clausen, Rasmus Prætorius, 2014, In: A C S Medicinal Chemistry Letters. 5, 4, p. 293-297Research output: Contribution to journal › Letter › Research › peer-review
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Ancient biosynthesis in an oil crop: Glucosinulate profiles in Limnanthes alba and its relatives (Limnanthaceae, Brassicales)
Agerbirk, Niels, Pattison, David, Mandáková, T., Lysak, M. A., Montaut, S. & Stærk, Dan, 2022, In: Journal of Agricultural and Food Chemistry. 70, p. 1134-1147Research output: Contribution to journal › Journal article › Research › peer-review
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Ancistrotanzanine A, the first 5,3’-coupled naphtylisoquinoline alkaloid, and two further, 5,8’-linked related compounds from the newly described species Ancistrocladus tanzaniensis
Bringmann, G., Dreyer, M., Faber, J. H., Dalsgaard, P. W., Stærk, Dan, Jaroszewski, J. W., Ndangalasi, H., Mbago, F., Brun, R., Reichert, M., Maksimenka, K. & Christensen, Søren Brøgger, 2003, In: Journal of Natural Products. 66, p. 1159-1165Research output: Contribution to journal › Journal article › Research › peer-review
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Ancistrotanzanine C and related 5,1’- and 7,3’- coupled naphtylisoquinoline alkaloids from Ancistrocladus tanzaniensis
Bringmann, G., Dreyer, M., Faber, J. H., Dalsgaard, P. W., Stærk, Dan, Jaroszewski, J. W., Ndangalasi, H., Mbago, F., Brun, R. & Christensen, Søren Brøgger, 2004, In: Journal of Natural Products. 67, p. 743-748Research output: Contribution to journal › Journal article › Research › peer-review
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Antidiabetic constituents of Dendrobium officinale as determined by high-resolution profiling of radical scavenging and α-glucosidase and α-amylase inhibition combined with HPLC-PDA-HRMS-SPE-NMR analysis.
Chu, C., Li, T., Pedersen, H. A., Kongstad, Kenneth Thermann, Yan, J. & Stærk, Dan, 2019, In: Phytochemistry Letters. 31, p. 47-52Research output: Contribution to journal › Journal article › Research › peer-review
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Antidiabetic xanthones with α-glucosidase inhibitory activities from an endophytic Penicillium canescens
Malik, A., Ardalani, H., Anam, S., McNair, Laura M., Kromphardt, K. J. K., Frandsen, R. J. N., Franzyk, Henrik, Stærk, Dan & Kongstad, Kenneth Thermann, 2020, In: Fitoterapia. 142, 8 p., 104522.Research output: Contribution to journal › Journal article › Research › peer-review
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Antimalarial sesquiterpene lactones from Distephanus angulifolius
Pedersen, M. M., Chukwujekwu, J. C., Lategan, C. A., van Staden, J., Smith, P. J. & Stærk, Dan, 2009, In: Phytochemistry. 70, 5, p. 601-607 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Application of Rotated PCA Models to Facilitate Interpretation of Metabolite Profiles: Commercial Preparations of St. John's Wort
Lawaetz, A. J., Schmidt, B., Stærk, Dan, Jaroszewski, J. W. & Bro, Rasmus, 2009, In: Planta Medica.Research output: Contribution to journal › Journal article › Research › peer-review
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Application of rotated PCA models to facilitate interpretation of metabolite profiles: commercial preparations of St. John's wort
Lawaetz, A. J., Schmidt, B., Stærk, Dan, Jaroszewski, J. W. & Bro, Rasmus, 2009, In: Planta Medica. 75, 3, p. 271-279 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Assessing specialized metabolite diversity in the cosmopolitan plant genus Euphorbia L.
Ernst, M., Nothias, L., van der Hooft, J. J. J., da Silva, R. R., Saslis-Lagoudakis, C. H., Grace, O. M., Martinez-Swatson, K. A., Hassemer, G., Funez, L. A., Simonsen, H. T., Medema, M. H., Stærk, Dan, Nilsson, N., Lovato, P., Dorrestein, P. C. & Rønsted, Nina, 2019, In: Frontiers in Plant Science. 10, 15 p., 846.Research output: Contribution to journal › Journal article › Research › peer-review
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Assessment of constituents in Allium by multivariate data analysis, high-resolution α-glucosidase inhibition assay and HPLC-SPE-NMR
Schmidt, J. S., Nyberg, N. & Stærk, Dan, 2014, In: Food Chemistry. 161, p. 192-198 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Assessment of the antidiabetic potential of selected medicinal plants using in vitro bioassays of muscle glucose transport and liver glucose production
Beidokhti, M. N., Sanchez Villavicencio, M. L., Eid, H. M., Stærk, Dan, Jäger, A. K. & Haddad, P. S., Dec 2016, In: Planta Medica. 81, S 01Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Athenolide A, a new steroidal lactone from the leaves of Athenaea martiana (Solanacea) determined by means of HPLC-HRMS-SPE-NMR analysis
Silva, E. L., Almeida-Lafetá, R. C., Borges, R. M. & Stærk, Dan, Jan 2018, In: Chemistry & Biodiversity. 15, 1, 8 p., e1700455.Research output: Contribution to journal › Journal article › Research › peer-review
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Biodiscoveries within the Australian plant genus Eremophila based on international and interdisciplinary collaboration: results and perspectives on outstanding ethical dilemmas
Semple, S., Stærk, Dan, Buirchell, B., Fowler, R., Gericke, Oliver, Kjaerulff, Louise, Zhao, Yong, Pedersen, H. A., Petersen, M. J., Rasmussen, L. F., Bredahl, E. K., Pedersen, Gustav Blichfeldt, McNair, Laura M., Ndi, C., Hansen, N. L., Heskes, A., Bayly, M., Loland, Claus Juul, Heinz, Nanna & Møller, Birger Lindberg, 2022, In: Plant Journal. 111, 4, p. 936-953 15866.Research output: Contribution to journal › Journal article › Research › peer-review
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Biosynthesis and biotechnological production of the anti-obesity agent celastrol
Zhao, Yong, Hansen, N. L., Duan, Yaotao, Prasad, M., Motawie, Mohammed Saddik, Møller, Birger Lindberg, Pateraki, Irini, Stærk, Dan, Bak, Søren, Miettinen, Karel & Kampranis, Sotirios, 2023, In: Nature Chemistry. 15, p. 1236–1246Research output: Contribution to journal › Journal article › Research › peer-review
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Biosynthesis of bioactive diterpenoids in the medicinal plant Vitex agnus-castus
Heskes, A., Sundram, T. C. M., Boughton, B. A., Bjerg Jensen, N., Hansen, N. L., Crocoll, C., Cozzi, F., Rasmussen, Simon, Hamberger, B., Hamberger, B. R., Stærk, Dan, Møller, Birger Lindberg & Pateraki, Irini, 2018, In: Plant Journal. 93, p. 943-958 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bis-intercalation of homodimeric thiazole orange dyes in DNA: effect of modifying the linker
Stærk, Dan, Hamed, A. A., Pedersen, E. B. & Jacobsen, J. P., 1997, In: Bioconjugate Chemistry. 8, p. 869-877Research output: Contribution to journal › Journal article › Research › peer-review
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Bisbenzylisoquinoline alkaloids as markers of Atherospermataceae: tetrandrine and fangchinoline from Laureliopsis philippiana
Stanstrup, Jan, Schmidt, J. S., Rasmussen, H. B., Mølgaard, Per, Guzmán, A. & Stærk, Dan, 2010, In: Biochemical Systematics and Ecology. 38, 3, p. 450-453 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Brazilian insulin plant as a bifunctional food: Dual high-resolution PTP1B and α-glucosidase inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of antidiabetic compounds in Myrcia rubella Cambess
Lima, R. D. C. L., Kato, L., Kongstad, Kenneth Thermann & Stærk, Dan, 2018, In: Journal of Functional Foods. 45, p. 444-451Research output: Contribution to journal › Journal article › Research › peer-review
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Butenolides from plant-derived smoke: natural plant-growth regulators with antagonistic actions on seed germination
Light, M. E., Burger, B. V., Stærk, Dan, Kohout, L. & Van Staden, J., 2010, In: Journal of Natural Products. 73, 2, p. 267-269 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of a membrane-bound C-glucosyltransferase responsible for carminic acid biosynthesis in Dactylopius coccus Costa
Kannangara, R. M., Siukstaite, L., Borch-Jensen, J., Madsen, B., Kongstad, Kenneth Thermann, Stærk, Dan, Bennedsen, M., Okkels, F. T., Rasmussen, S. A., Larsen, T. O., Frandsen, R. J. N. & Møller, Birger Lindberg, 2017, In: Nature Communications. 8, 12 p., 1987.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of antidiabetic serrulatane diterpenoids from Eremophila phyllopoda by triple high-resolution α-glucosidase / PTP1B / radical scavenging profiling
Liang, Chao, Ndi, C., Semple, S., Coriani, S., Møller, Birger Lindberg & Stærk, Dan, 2021. 1 p.Research output: Contribution to conference › Poster › Research
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Characterization of antileishmanial compounds from Lawsonia inermis leaves using semi-high resolution antileishmanial profiling combined with HPLC-HRMS-SPE-NMR
Iqbal, K., Iqbal, J., Stærk, Dan & Kongstad, Kenneth Thermann, 2017, In: Frontiers in Pharmacology. 8, 7 p., 337.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of serrulatane diterpenoids in Eremophila phyllopoda subsp. phyllopoda by triple high-resolution α-glucosidase/PTP1B/radical scavenging profiling, NMR spectroscopy, DFT-GIAO NMR, and electronic circular dichroism calculations
Liang, Chao, Ndi, C., Kjaerulff, Louise, Semple, S., Buirchell, B., Coriani, S., Møller, Birger Lindberg & Stærk, Dan, 2023, In: Journal of Natural Products. 86, 4, p. 694–709Research output: Contribution to journal › Journal article › Research › peer-review
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Combined magnetic ligand fishing and high-resolution inhibition profiling for identification of α-glucosidase inhibitory ligands: A new screening approach based on complementary inhibition and affinity profiles.
Wubshet, S. G., Liu, B., Kongstad, Kenneth Thermann, Böcker, U., Petersen, M. J., Li, T., Wang, J. & Stærk, Dan, 2019, In: Talanta. 200, p. 279-287Research output: Contribution to journal › Journal article › Research › peer-review
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Combined use of high-resolution α-glucosidase inhibition profiling and HPLC-HRMS-SPE-NMR for investigation of antidiabetic principles in crude plant extracts
Kongstad, Kenneth Thermann, Özdemir, C., Barzak, A., Wubshet, S. G. & Stærk, Dan, 5 Feb 2015, In: Journal of Agricultural and Food Chemistry. 63, 8, p. 2257-2263 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Combining HPLC-PDA-MS-SPE-NMR with circular dichroism for complete natural product characterization in crude extracts: Levorotatory gossypol in Thespesia danis
Sprogøe, K., Stærk, Dan, Ziegler, H. L., Jensen, T. H., Holm-Møller, S. B. & Jaroszewski, J. W., 2008, In: Journal of Natural Products. 71, 4, p. 516-519Research output: Contribution to journal › Journal article › Research › peer-review
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Combining PARAFAC analysis of HPLC-PDA profiles and structural characterization using HPLC-PDA-SPE-NMR-MS experiments: commercial preparations of St. John's Wort
Schmidt, B., Jaroszewski, J. W., Bro, Rasmus, Witt, M. & Stærk, Dan, 2008, In: Analytical Chemistry. 80, 6, p. 1978-1987 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Comparative study of the drug delivery mechanism of L-penetratin and D-penetratin
Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2018.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Comprehensive analysis of commercial willow bark extracts by new technology platform: combined use of metabolomics, high-perfomance liquid chromatography-solid-phase extraction-nuclear magnetic resonance spectroscopy and high-resolution radical scavenging assay
Agnolet, S., Wiese, S., Verpoorte, R. & Stærk, Dan, 2012, In: Journal of Chromatography A. 1262, p. 130-137 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Conformational studies of indole alkaloids corynantheine and dihydrocorynantheine by dynamic 1H NMR spectroscopy and computational methods: steric effects of ethyl vs. vinyl group
Stærk, Dan, Norrby, P. & Jaroszewski, J. W., 2001, In: Journal of Organic Chemistry. 66, p. 2217-2221Research output: Contribution to journal › Journal article › Research › peer-review
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Coupling HPLC-SPE-NMR with a microplate-based high-resolution antioxidant assay for efficient analysis of antioxidants in food – Validation and proof-of-concept study with caper buds
Wiese, S., Wubshet, S. G., Nielsen, J. & Stærk, Dan, 2013, In: Food Chemistry. 141, 4, p. 4010-4018Research output: Contribution to journal › Journal article › Research › peer-review
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Coupling microplate-based antibacterial assay with liquid chromatography for high-resolution growth inhibition profiling of crude extracts: Validation and proof-of-concept study with Staphylococcus aureus
Ardalani, H., Anam, S., Kromphardt, K. J. K., Stærk, Dan & Kongstad, Kenneth Thermann, 2021, In: Molecules. 26, 6, 12 p., 1550.Research output: Contribution to journal › Journal article › Research › peer-review
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Coupling of a high-resolution monoamine oxidase-A inhibitor assay and HPLC-SPE-NMR for advanced bioactivity-profiling of plant extracts
Grosso, C., Jäger, A. & Stærk, Dan, 2013, In: Phytochemical Analysis. 24, 2, p. 141-147Research output: Contribution to journal › Journal article › Research › peer-review
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Cytotoxic activity of some phenanthroindolizidine N-Oxide alkaloids from Cynanchum vincetoxicum
Stærk, Dan, Christensen, J., Lemmich, E., Duus, J. Ø., Olsen, C. E. & Jaroszewski, J. W., 2000, In: Journal of Natural Products. 63, 11, p. 1584-1586Research output: Contribution to journal › Journal article › Research › peer-review
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Data-dependent acquisition-mass spectrometry guided isolation of new benzoxazinoids from the roots of Acanthus mollis L.
Bhattarai, B., Steffensen, S. K., Stærk, Dan, Laursen, B. B. & Fomsgaard, I. S., 2022, In: International Journal of Mass Spectrometry. 474, 10 p., 116815.Research output: Contribution to journal › Journal article › Research › peer-review
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Detection of Seasonal Variation in Aloe Polysaccharides Using Carbohydrate Detecting Microarrays
Isager Ahl, Louise, Al-Husseini, N., Al-Helle, S., Stærk, Dan, Grace, O. M., Willats, W. G. T., Mravec, Jozef, Jørgensen, Bodil & Rønsted, Nina, 2019, In: Frontiers in Plant Science. 10, p. 1-14 512.Research output: Contribution to journal › Journal article › Research › peer-review
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Development of a bioassay-coupled HPLC-SPE-ttNMR platform for identification of α-glucosidase inhibitors in apple peel (Malus × domestica Borkh.)
Schmidt, J. S., Lauridsen, M. B., Dragsted, Lars Ove, Nielsen, J. & Stærk, Dan, 2012, In: Food Chemistry. 135, 3, p. 1692-1699 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Discovering new natural products directly from crude extracts by HPLC-SPE-NMR: chinane diterpenes in Harpagophytum procumbens
Clarkson, C., Stærk, Dan, Hansen, S. H., Smith, P. J. & Jaroszewski, J. W., 2006, In: Journal of Natural Products. 69, p. 527-530Research output: Contribution to journal › Journal article › Research › peer-review
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Dovyalicin-type spermidine alkaloids from Dovyalis species
Rasmussen, B., Nkurunziza, A., Witt, M., Oketch-Rabah, H. A., Jaroszewski, J. W. & Stærk, Dan, 2006, In: Journal of Natural Products. 69, p. 1300-1304Research output: Contribution to journal › Journal article › Research › peer-review
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Dual High-Resolution α-Glucosidase and Radical Scavenging Profiling Combined with HPLC-HRMS-SPE-NMR for Identification of Minor and Major Constituents Directly from the Crude Extract of Pueraria lobata
Liu, B., Kongstad, Kenneth Thermann, Qinglei, S., Nyberg, N., Jäger, A. & Stærk, Dan, 13 Feb 2015, In: Journal of Natural Products. 78, 2, p. 294–300 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dual high-resolution inhibition profiling and HPLC-HRMS-SPE-NMR analysis for identification of α-glucosidase and radical scavenging inhibitors in Solanum americanum Mill.
Silva, E. L. E., Almeida-Lafetá, R. C., Borges, R. M. & Stærk, Dan, 2017, In: Fitoterapia. 118, p. 42-48Research output: Contribution to journal › Journal article › Research › peer-review
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Dual high-resolution α-glucosidase and PTP1B profiling combined with HPLC-PDA-HRMS-SPE-NMR analysis for the identification of potentially antidiabetic chromene meroterpenoids in Rhododendron capitatum
Liang, Chao, Kjaerulff, Louise, Hansen, Paul Robert, Kongstad, Kenneth Thermann & Stærk, Dan, 2021, In: Journal of Natural Products. 84, p. 2454-2467Research output: Contribution to journal › Journal article › Research › peer-review
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Edible seaweed as future functional food: Identification of α-glucosidase inhibitors by combined use of high-resolution α-glucosidase inhibition profiling and HPLC-HRMS-SPE-NMR
Liu, B., Kongstad, Kenneth Thermann, Wiese, S., Jäger, A. K. & Stærk, Dan, 2016, In: Food Chemistry. 203, p. 16-22 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of residual water and microwave heating on half-lifes of reagents and reactive intermediates in peptide synthesis
Shelton, A. P. T., Pedersen, S. L., Stærk, Dan & Jensen, Knud Jørgen, 2012, In: Chemistry: A European Journal. 18, 29, p. 9024-9031 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Efficient and versatile COMU-mediated solid-phase submonomer synthesis of arylopeptoids (oligomeric N-substituted aminomethyl benzamides)
Hjelmgaard, T., Faure, S., Stærk, Dan, Taillefumier, C. & Nielsen, J., 2011, In: Organic & Biomolecular Chemistry. 9, p. 6832-6843 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Eremane, viscidane and isozizaene diterpenoids from the leaves of Eremophila rigida and their absolute configurations
Liang, Chao, Ndi, C., Semple, S., Buirchell, B., Coriani, S., Møller, Birger Lindberg & Stærk, Dan, 2024, In: Phytochemistry. 219, 16 p., 113972.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Erratum: "Naravelia zeylanica: Occurrence of primary benzamides in flowering plants" (Natural Product Research vol. 19 (3) (291-294))
Jaroszewski, J. W., Stærk, Dan, Holm-Møller, S. B., Jensen, T. H., Franzyk, Henrik & Somanadhan, B., 1 Jun 2005, In: Natural Product Research. 19, 4, 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Erythrocyte membrane modifying agents and the inhibition of Plasmodium falciparum growth: structure-activity relationships for betulinic acid analogues
Ziegler, H. L., Franzyk, Henrik, Sairafianpour, M., Tabatabai, M., Tehrani, M. D., Bagherzadeh, K., Hägerstrand, H., Stærk, Dan & Jaroszewski, J. W., 2004, In: Bioorganic & Medicinal Chemistry. 12, p. 119-127Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of the antidiabetic potential of Psidium guajava L. (Myrtaceae) using assays for α-glucosidase, α-amylase, muscle glucose uptake, liver glucose production and triglyceride accumulation in adipocytes
Beidokhti, M. N., Eid, H. M., Villavicencio, M. L. S., Jäger, A. K., Lobbens, E. S., Rasoanaivo, P. R., McNair, Laura M., Haddad, P. S. & Stærk, Dan, 17 Apr 2020, In: Journal of Ethnopharmacology. 257, 8 p., 112877.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expanding the landscape of diterpene structural diversity by stereochemically controlled combinatorial biosynthesis
Andersen-Ranberg, Johan, Kongstad, Kenneth Thermann, Nielsen, M. T., Bjerg Jensen, N., Pateraki, Irini, Bach, S. S., Hamberger, B., Zerbe, P., Stærk, Dan, Bohlmann, J., Møller, Birger Lindberg & Hamberger, B. R., 2016, In: Angewandte Chemie International Edition. 55, 6, p. 2142-2146 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Expanding the terpene biosynthetic code with non-canonical 16 carbon atom building blocks
Ignea, C., Raadam, Morten Hessellund, Koutsaviti, A., Zhao, Yong, Duan, Yaotao, Harizani, M., Miettinen, Karel, Georgantea, P., Rosenfeldt, M., Viejo-Ledesma, S. E., Petersen, Mikael Agerlin, Bredie, Wender, Stærk, Dan, Roussis, V., Ioannou, E. & Kampranis, Sotirios, 2022, In: Nature Communications. 13, 16 p., 5188.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expedient solution-phase synthesis and NMR studies of arylopeptoids
Hjelmgaard, T., Faure, S., Stærk, Dan, Taillefumier, C. & Nielsen, J., 2011, In: European Journal of Organic Chemistry. 2011, 22, p. 4121-4132 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Facilitated visual interpretation of scores in principal component analysis by bioactivity-labeling of 1H NMR spectra - metabolomics investigation and identification of a new α-glucosidase inhibitor in Radix Astragali
Liu, Y., Nyberg, N., Jäger, A. K. & Stærk, Dan, 2017, In: Molecules. 22, 3, 12 p., 411.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fluorophore labeling of a cell-penetrating peptide induces differential effects on its cellular distribution and affects cell viability
Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2017, In: B B A - Biomembranes. 1859, 12, p. 2483-2494Research output: Contribution to journal › Journal article › Research › peer-review
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Food preference and performance of the larvae of a specialist herbivore: variation among and within host-plant populations
Leimu, R., Riipi, M. & Stærk, Dan, 2005, In: Acta Oecologica. 28, p. 325-330Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Forbedret test af nye lægemidler mod malaria
Christensen, J., Stærk, Dan, Ziegler, H. L., Sairafianpour, M. & Jaroszewski, J. W., 2001, In: Lægemiddelforskning. p. 8-9Research output: Contribution to journal › Journal article › Communication
- Published
Fremtidens bæredygtige medicin fra naturen: Nye teknologier hjælper med at finde nålen i høstakken
Stærk, Dan, 2022, In: Pharma. 2022, 2, p. 20-22Research output: Contribution to journal › Contribution to newspaper - Newspaper article › Communication
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Fremtidens funktionelle fødevarer - et vigtigt middel i kampen mod livsstilssygdomme
Stærk, Dan, 2012, Profil/Fødevarer & Sundhed. København: Københavns Universitet, Kommunikation, p. 18-19 2 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
- Published
Fungal plasma membrane H+-ATPase inhibitory activity of o-hydroxybenzylated flavanones and chalcones from Uvaria chamae P. Beauv
Kongstad, Kenneth Thermann, Wubshet, S. G., Kjellerup, L., winther, A. L. & Stærk, Dan, 20 Jun 2015, In: Fitoterapia. 105, p. 102-106 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Furolabdane diterpenoids from Pseudodictamnus aucheri (Boiss.) Salmaki & Siadati (Lamiaceae) as chemophenetic markers
Sadani, S., Sarrafi, Y. & Stærk, Dan, 2021, In: Biochemical Systematics and Ecology. 98, 4 p., 104304.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
HPLC-HRMS-SPE-NMR combined with high resolution in vitro screening for natural fungicides
Kongstad, Kenneth Thermann, Wubshet, S. G., Kjellerup, L., Winther, A. & Stærk, Dan, Dec 2016, In: Planta Medica. 82, S 01Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
HPLC-HRMS-SPE-NMR for accelerated identification of compounds in complex plant extracts: New coumarine derivatives from Coleonema album (Thunb.) Bartl. & Wendl
de Cássia Lemos Lima, R., Gramsbergen, S. M., Van Staden, J., Jäger, A. K., Kongstad, Kenneth Thermann & Stærk, Dan, Dec 2016, In: Planta Medica. 82, S 01Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
HPLC-NMR Techniques for Plant Extract Analysis
Stærk, Dan, Lambert, M. & Jaroszewski, J. W., 20 Mar 2008, Medicinal Plant Biotechnology: From Basic Research to Industrial Applications. Wiley-VCH, p. 29-48 20 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
HPLC-NMR techniques for plant extract analysis
Stærk, Dan, Lambert, M. & Jaroszewski, J. W., 2006, Medicinal Plant Biotechnology. From Basic Research to Applications. Kayser, O. & Quax, W. J. (eds.). Weinheim: Wiley-VCH, p. 29-48Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
- Published
HPLC-SPE-NMR hyphenation in natural products research: optimization of analysis of Croton membranaceus extract
Lambert, M., Stærk, Dan, Hansen, S. H. & Jaroszewski, J. W., 2005, In: Magnetic Resonance in Chemistry. 43, p. 771-775Research output: Contribution to journal › Journal article › Research › peer-review
- Published
HPLC-SPE-NMR identification of a novel metabolite containing the benzo[c]oxepin skeleton from the endophytic fungus Pestalotiopsis virgatula culture
Kesting, J. R., Stærk, Dan, Tejesvi, M. V., Kini, K. R., Prakash, H. S. & Jaroszewski, J. W., 2009, In: Planta Medica. 75, 10, p. 1104-1106 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hemolymph metabolites and osmolality are tightly linked to cold tolerance of Drosophila species: a comparative study
Olsson, T., MacMillan, H. A., Nyberg, N., Stærk, Dan, Malmendal, A. & Overgaard, J., 15 Aug 2016, In: The Journal of Experimental Biology. 219, 16, p. 2504-2513 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heterologous production of the widely used natural food colorant carminic acid in Aspergillus nidulans
Frandsen, R. J. N., Khorsand-Jamal, P., Kongstad, Kenneth Thermann, Nafisi, M., Kannangara, R. M., Stærk, Dan, Okkels, F. T., Binderup, K., Madsen, B., Møller, Birger Lindberg, Thrane, U. & Mortensen, U. H., 2018, In: Scientific Reports. 8, p. 1-10 10 p., 12853.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High resolution antioxidant assay guided HPLC-HRMS-SPE-NMR analysis of Penicillium namyslowskii extract
Wubshet, S. G., Nyberg, N. & Stærk, Dan, 2012.Research output: Contribution to conference › Poster › Research
- Published
High resolution techniques: General discussion
Adair, E., Afonso, C., Bell, N. G. A., Davies, A. N., Delsuc, M. A., Godfrey, R., Goodacre, R., Hawkes, J. A., Hertkorn, N., Jones, D., Lameiras, P., Le Guennec, A., Lubben, A., Nilsson, M., Paša-Tolić, L., Richards, J., Rodgers, R. P., Rüger, C. P., Schmitt-Kopplin, P., Schoenmakers, P. J. & 8 others, , 1 Jan 2019, In: Faraday Discussions. 218, p. 247-267 21 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
High-dose naloxone, an experimental tool uncovering latent sensitisation: pharmacokinetics in humans.
Papathanasiou, T., Springborg, A., Kongstad, Kenneth Thermann, Stærk, Dan, Møller, Kirsten, Taylor, B. K., Lund, Trine Meldgaard & Werner, M. U., 2019, In: British Journal of Anaesthesia. 123, 2, p. e204-e214Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-resolution Assays Combined with HPLC-HRMS-SPE-ttNMR for Identification of Antidiabetic Compounds in root of Scutellaria Baicalensis
Tahtah, Y., Jønsson, L. H., Nyberg, N., Jäger, A. & Stærk, Dan, 2014.Research output: Contribution to conference › Poster › Research
- Published
High-resolution PTP1B inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of PTP1B inhibitors from Miconia albicans
Lima, R. D. C. L., Kongstad, Kenneth Thermann, Kato, L., José das Silva, M., Franzyk, Henrik & Stærk, Dan, 2018, In: Molecules. 23, 7, 13 p., 1755.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-resolution PTP1B inhibition profiling combined with high-performance liquid chromatography - high-resolution mass spectrometry - solid-phase extraction - nuclear magnetic resonance spectroscopy: Proof-of-concept and antidiabetic constituents in crude extract of Eremophila lucida
Tahtah, Y., Wubshet, S. G., Kongstad, Kenneth Thermann, Heskes, A. M., Pateraki, Irini, Møller, Birger Lindberg, Jäger, A. & Stærk, Dan, 2016, In: Fitoterapia. 110, p. 52-58 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-resolution assays combined with HPLC for identification of antidiabetic constituents in Vietnamese plants
Trinh, T. D. B., Stærk, Dan & Jäger, A. K., 26 Aug 2015.Research output: Contribution to conference › Poster › Research
- Published
High-resolution bacterial growth inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of antibacterial constituents in Chinese plants used to treat snakebites
Liu, Y., Nielsen, M., Stærk, Dan & Jäger, A., 2014, In: Journal of Ethnopharmacology. 155, 2, p. 1276-1283 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1299056
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Identification of α-glucosidase inhibitors in apple peel - a chemometric approach
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Itoside A and 4-hydroxytremulacin from Dovyalis caffra and Dovyalis zeyheri
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Identification of reaction products between drug substances and excipients by HPLC-SPE-NMR: Ester and amide formation between citric acid and 5-aminosalicylic acid
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