Dan Stærk

Dan Stærk

Head of Department, Visiting professor

ORCID: 0000-0003-0074-298X

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  1. Published

    2(5H)-Furanone sesquiterpenes from Eremophila bignoniiflora: High-resolution inhibition profiling and PTP1B inhibitory activity

    Zhao, Yong, Kjaerulff, Louise, Kongstad, Kenneth Thermann, Heskes, A. M., Møller, Birger Lindberg & Stærk, Dan, 2019, In: Phytochemistry. 166, p. 1-8 112054.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    4-Benzyloxylonchocarpin and muracatanes A-C from Ranunculus muricatus L. and their biological effects

    Hussain, H., Ali, I., Wang, D., Mamadalieva, N. Z., Hussain, W., Csuk, R., Loesche, A., Fischer, L., Stærk, Dan, Anam, S., AlZain, M. N., Mushtaq, M., Ul-Haq, Z., Ullah, R., Noman, O. M., Abbas, G. & Green, I. R., 2020, In: Biomolecules. 10, 11, 15 p., 1562.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    In vitro Plasmodium falciparum drug sensitivity assay: inhibition of parasite growth by incorporation of stomatocytogenic amphiphiles into the erythrocyte membrane

    Ziegler, H. L., Stærk, Dan, Christensen, J., Hviid, Lars, Hägerstrand, H. & Jaroszewski, J. W., 2002, In: Antimicrobial Agents and Chemotherapy. 46, 5, p. 1441-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Naravelia zeyanica: occurrence of primary benzamides in flowering plants

    Jaroszewski, J. W., Stærk, Dan, Holm-Møller, S. B., Jensen, T. H. & Franzyk, Henrik, 2005, In: Natural Product Research. 19, 3, p. 291-294

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Tripterygium wilfordii cytochrome P450s catalyze the methyl shift and epoxidations in the biosynthesis of triptonide

    Hansen, N. L., Kjaerulff, Louise, Heck, Q. K., Forman, Victor, Stærk, Dan, Møller, Birger Lindberg & Andersen-Ranberg, Johan, 2022, In: Nature Communications. 13, 5011.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    19F-substituted amino acids as an alternative to fluorophore labels: monitoring of degradation and cellular uptake of analogues of penetratin by 19F NMR

    Christensen, M. V., Kongstad, Kenneth Thermann, Sondergaard, T. E., Stærk, Dan, Nielsen, Hanne Mørck, Franzyk, Henrik & Wimmer, R., 2019, In: Journal of Biomolecular N M R. 73, p. 167-182

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    1H NMR-based metabolomics applied to study of complex pharmaceutical extracts of Ginkgo biloba

    Agnolet, S., Jaroszewski, J. W. & Stærk, Dan, 2009.

    Research output: Contribution to conference › Conference abstract for conference › Research

  8. Published

    1H NMR-based metabolomics combined with HPLC-PDA-MS-SPE-NMR for investigation of standardized Ginkgo biloba preparations

    Agnolet, S., Jaroszewski, J. W., Verpoorte, R. & Stærk, Dan, 2010, In: Metabolomics. 6, 2, p. 292-302 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    1H-NMR based metabolomics applied to standardized Ginkgo biloba preparations

    Agnolet, S., Jaroszewski, J. W., Verpoorte, R. & Stærk, Dan, 2009.

    Research output: Contribution to conference › Conference abstract for conference › Research

  10. Published

    1H-NMR based metabolomics applied to standardized Ginkgo biloba preparations

    Agnolet, S., Jaroszewski, J. W., Verpoorte, R. & Stærk, Dan, 2009.

    Research output: Contribution to conference › Conference abstract for conference › Research

  11. Published

    4N-alkyloxycarbonyl derivatives of cytosine: physicochemical characterisation, and cytosine regeneration rates and release from alginic acid gels

    Petersson, K. P., Pedersen, B. T., Stærk, Dan, Krogfelt, K. A. & Larsen, C. S., 2004, In: European Journal of Pharmaceutical Sciences. 23, 4-5, p. 337-345

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    A 5-deoxyflavonol derivative in Mimosa pudica

    Kirk, L. F., Møller, M. V., Christensen, J., Stærk, Dan, Ekpe, P. & Jaroszewski, J. W., 2003, In: Biochemical Systematics and Ecology. 31, 1, p. 103-105

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    A GPCR-based yeast biosensor for biomedical, biotechnological, and point-of-use cannabinoid determination

    Miettinen, Karel, Leelahakorn, Nattawat, Almeida Robles, A. R., Zhao, Yong, Hansen, L. R., Nikolajsen, I. E., Andersen, Jens Bo, Givskov, Michael, Stærk, Dan, Bak, Søren & Kampranis, Sotirios, 2022, In: Nature Communications. 13, 16 p., 3664.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    A gene cluster in Ginkgo biloba encodes unique multifunctional cytochrome P450s that initiate ginkgolide biosynthesis

    Forman, Victor, Luo, Dan, Geu-Flores, Fernando, Lemcke, René, Nelson, D., Kampranis, Sotirios, Stærk, Dan, Møller, Birger Lindberg & Pateraki, Irini, 2022, In: Nature Communications. 13, 14 p., 5143.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    A new class of spermidine-derived alkaloids

    Stærk, Dan, Witt, M., Oketch-Rabah, H. A. & Jaroszewski, J. W., 2003, In: Organic Letters. 5, p. 2793-2796

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    A systematic review of possible interactions for herbal medicines and dietary supplements used concomitantly with disease-modifying or symptom-alleviating multiple sclerosis drugs

    Petersen, M. J., Bergien, Sofie Olsgaard & Stærk, Dan, 2021, In: Phytotherapy Research. 35, 7, p. 3610-3631

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Accelerated dereplication of crude extracts using HPLC-PDA-MS-SPE-NMR

    Stærk, Dan, Kesting, J. R., Sairafianpour, M., Witt, M., Asili, J., Emami, S. A. & Jaroszewski, J. W., 2009, In: Phytochemistry. 70, 8, p. 1055-1061 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Accelerating drug lead discovery from nature by high-resolution bioactivity profiling combined with HPLC-HRMS-SPE-NMR

    Kongstad, Kenneth Thermann, Nyberg, N. T., Wubshet, S. G. & Stærk, Dan, Dec 2016, In: Planta Medica. 81, S 01

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  19. Published

    Advancing HPLC-PDA-HRMS-SPE-NMR analysis of coumarins in Coleonema album by use of orthogonal reversed-phase C18 and pentafluorophenyl separations

    Lima, R. D. C. L., Gramsbergen, S., Van Staden, J., Jäger, A. K., Kongstad, Kenneth Thermann & Stærk, Dan, 2017, In: Journal of Natural Products. 80, 4, p. 1020-1027

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    African plants for inhibition of necrotic enzymes from snake venom

    Schmidt, M. M., Nielsen, L., Søgaard, S., Stærk, Dan, Rønsted, Nina, Diallo, D., Kusamba Zacharie, C., Van Staden, J. & Jäger, A. K., 2014.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  21. Published

    An independent evolutionary origin for insect deterrent cucurbitacins in Iberis amara

    Dong, L., Almeida Robles, A. R., Pollier, J., Khakimov, Bekzod, Bassard, J. A., Miettinen, K., Stærk, Dan, Mehran, R., Olsen, C. E., Motawie, Mohammed Saddik, Goossens, A. & Bak, Søren, 2021, In: Molecular Biology and Evolution. 38, 11, p. 4659-4673 15 p., msab213.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    An inverse association between plasma benzoxazinoid metabolites and PSA after rye intake in men with prostate cancer revealed with a new method

    Nordin, E., Steffensen, S. K., Laursen, B. B., Andersson, S., Johansson, J., Åman, P., Hallmans, G., Borre, M., Stærk, Dan, Hanhineva, K., Fomsgaard, I. S. & Landberg, R., 2022, In: Scientific Reports. 12, 14 p., 5260.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Analogues of the natural product Sinefungin as inhibitors of EHMT1 and EHMT2

    Devkota, K., Lohse, B., Liu, Q., Wang, M., Stærk, Dan, Berthelsen, J. & Clausen, Rasmus Prætorius, 2014, In: A C S Medicinal Chemistry Letters. 5, 4, p. 293-297

    Research output: Contribution to journal › Letter › Research › peer-review

  24. Published

    Ancient biosynthesis in an oil crop: Glucosinulate profiles in Limnanthes alba and its relatives (Limnanthaceae, Brassicales)

    Agerbirk, Niels, Pattison, David, Mandáková, T., Lysak, M. A., Montaut, S. & Stærk, Dan, 2022, In: Journal of Agricultural and Food Chemistry. 70, p. 1134-1147

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Ancistrotanzanine A, the first 5,3’-coupled naphtylisoquinoline alkaloid, and two further, 5,8’-linked related compounds from the newly described species Ancistrocladus tanzaniensis

    Bringmann, G., Dreyer, M., Faber, J. H., Dalsgaard, P. W., Stærk, Dan, Jaroszewski, J. W., Ndangalasi, H., Mbago, F., Brun, R., Reichert, M., Maksimenka, K. & Christensen, Søren Brøgger, 2003, In: Journal of Natural Products. 66, p. 1159-1165

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Ancistrotanzanine C and related 5,1’- and 7,3’- coupled naphtylisoquinoline alkaloids from Ancistrocladus tanzaniensis

    Bringmann, G., Dreyer, M., Faber, J. H., Dalsgaard, P. W., Stærk, Dan, Jaroszewski, J. W., Ndangalasi, H., Mbago, F., Brun, R. & Christensen, Søren Brøgger, 2004, In: Journal of Natural Products. 67, p. 743-748

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Antidiabetic constituents of Dendrobium officinale as determined by high-resolution profiling of radical scavenging and α-glucosidase and α-amylase inhibition combined with HPLC-PDA-HRMS-SPE-NMR analysis.

    Chu, C., Li, T., Pedersen, H. A., Kongstad, Kenneth Thermann, Yan, J. & Stærk, Dan, 2019, In: Phytochemistry Letters. 31, p. 47-52

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Antidiabetic xanthones with α-glucosidase inhibitory activities from an endophytic Penicillium canescens

    Malik, A., Ardalani, H., Anam, S., McNair, Laura M., Kromphardt, K. J. K., Frandsen, R. J. N., Franzyk, Henrik, Stærk, Dan & Kongstad, Kenneth Thermann, 2020, In: Fitoterapia. 142, 8 p., 104522.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Antimalarial sesquiterpene lactones from Distephanus angulifolius

    Pedersen, M. M., Chukwujekwu, J. C., Lategan, C. A., van Staden, J., Smith, P. J. & Stærk, Dan, 2009, In: Phytochemistry. 70, 5, p. 601-607 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Application of Rotated PCA Models to Facilitate Interpretation of Metabolite Profiles: Commercial Preparations of St. John's Wort

    Lawaetz, A. J., Schmidt, B., Stærk, Dan, Jaroszewski, J. W. & Bro, Rasmus, 2009, In: Planta Medica.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Application of rotated PCA models to facilitate interpretation of metabolite profiles: commercial preparations of St. John's wort

    Lawaetz, A. J., Schmidt, B., Stærk, Dan, Jaroszewski, J. W. & Bro, Rasmus, 2009, In: Planta Medica. 75, 3, p. 271-279 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Assessing specialized metabolite diversity in the cosmopolitan plant genus Euphorbia L.

    Ernst, M., Nothias, L., van der Hooft, J. J. J., da Silva, R. R., Saslis-Lagoudakis, C. H., Grace, O. M., Martinez-Swatson, K. A., Hassemer, G., Funez, L. A., Simonsen, H. T., Medema, M. H., Stærk, Dan, Nilsson, N., Lovato, P., Dorrestein, P. C. & Rønsted, Nina, 2019, In: Frontiers in Plant Science. 10, 15 p., 846.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Assessment of constituents in Allium by multivariate data analysis, high-resolution α-glucosidase inhibition assay and HPLC-SPE-NMR

    Schmidt, J. S., Nyberg, N. & Stærk, Dan, 2014, In: Food Chemistry. 161, p. 192-198 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Assessment of the antidiabetic potential of selected medicinal plants using in vitro bioassays of muscle glucose transport and liver glucose production

    Beidokhti, M. N., Sanchez Villavicencio, M. L., Eid, H. M., Stærk, Dan, Jäger, A. K. & Haddad, P. S., Dec 2016, In: Planta Medica. 81, S 01

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  35. Published

    Athenolide A, a new steroidal lactone from the leaves of Athenaea martiana (Solanacea) determined by means of HPLC-HRMS-SPE-NMR analysis

    Silva, E. L., Almeida-Lafetá, R. C., Borges, R. M. & Stærk, Dan, Jan 2018, In: Chemistry & Biodiversity. 15, 1, 8 p., e1700455.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Biodiscoveries within the Australian plant genus Eremophila based on international and interdisciplinary collaboration: results and perspectives on outstanding ethical dilemmas

    Semple, S., Stærk, Dan, Buirchell, B., Fowler, R., Gericke, Oliver, Kjaerulff, Louise, Zhao, Yong, Pedersen, H. A., Petersen, M. J., Rasmussen, L. F., Bredahl, E. K., Pedersen, Gustav Blichfeldt, McNair, Laura M., Ndi, C., Hansen, N. L., Heskes, A., Bayly, M., Loland, Claus Juul, Heinz, Nanna & Møller, Birger Lindberg, 2022, In: Plant Journal. 111, 4, p. 936-953 15866.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Biosynthesis and biotechnological production of the anti-obesity agent celastrol

    Zhao, Yong, Hansen, N. L., Duan, Yaotao, Prasad, M., Motawie, Mohammed Saddik, Møller, Birger Lindberg, Pateraki, Irini, Stærk, Dan, Bak, Søren, Miettinen, Karel & Kampranis, Sotirios, 2023, In: Nature Chemistry. 15, p. 1236–1246

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Biosynthesis of bioactive diterpenoids in the medicinal plant Vitex agnus-castus

    Heskes, A., Sundram, T. C. M., Boughton, B. A., Bjerg Jensen, N., Hansen, N. L., Crocoll, C., Cozzi, F., Rasmussen, Simon, Hamberger, B., Hamberger, B. R., Stærk, Dan, Møller, Birger Lindberg & Pateraki, Irini, 2018, In: Plant Journal. 93, p. 943-958 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Bis-intercalation of homodimeric thiazole orange dyes in DNA: effect of modifying the linker

    Stærk, Dan, Hamed, A. A., Pedersen, E. B. & Jacobsen, J. P., 1997, In: Bioconjugate Chemistry. 8, p. 869-877

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Bisbenzylisoquinoline alkaloids as markers of Atherospermataceae: tetrandrine and fangchinoline from Laureliopsis philippiana

    Stanstrup, Jan, Schmidt, J. S., Rasmussen, H. B., Mølgaard, Per, Guzmán, A. & Stærk, Dan, 2010, In: Biochemical Systematics and Ecology. 38, 3, p. 450-453 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Brazilian insulin plant as a bifunctional food: Dual high-resolution PTP1B and α-glucosidase inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of antidiabetic compounds in Myrcia rubella Cambess

    Lima, R. D. C. L., Kato, L., Kongstad, Kenneth Thermann & Stærk, Dan, 2018, In: Journal of Functional Foods. 45, p. 444-451

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Butenolides from plant-derived smoke: natural plant-growth regulators with antagonistic actions on seed germination

    Light, M. E., Burger, B. V., Stærk, Dan, Kohout, L. & Van Staden, J., 2010, In: Journal of Natural Products. 73, 2, p. 267-269 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Characterization of a membrane-bound C-glucosyltransferase responsible for carminic acid biosynthesis in Dactylopius coccus Costa

    Kannangara, R. M., Siukstaite, L., Borch-Jensen, J., Madsen, B., Kongstad, Kenneth Thermann, Stærk, Dan, Bennedsen, M., Okkels, F. T., Rasmussen, S. A., Larsen, T. O., Frandsen, R. J. N. & Møller, Birger Lindberg, 2017, In: Nature Communications. 8, 12 p., 1987.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Characterization of antidiabetic serrulatane diterpenoids from Eremophila phyllopoda by triple high-resolution α-glucosidase / PTP1B / radical scavenging profiling

    Liang, Chao, Ndi, C., Semple, S., Coriani, S., Møller, Birger Lindberg & Stærk, Dan, 2021. 1 p.

    Research output: Contribution to conference › Poster › Research

  45. Published

    Characterization of antileishmanial compounds from Lawsonia inermis leaves using semi-high resolution antileishmanial profiling combined with HPLC-HRMS-SPE-NMR

    Iqbal, K., Iqbal, J., Stærk, Dan & Kongstad, Kenneth Thermann, 2017, In: Frontiers in Pharmacology. 8, 7 p., 337.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Characterization of serrulatane diterpenoids in Eremophila phyllopoda subsp. phyllopoda by triple high-resolution α-glucosidase/PTP1B/radical scavenging profiling, NMR spectroscopy, DFT-GIAO NMR, and electronic circular dichroism calculations

    Liang, Chao, Ndi, C., Kjaerulff, Louise, Semple, S., Buirchell, B., Coriani, S., Møller, Birger Lindberg & Stærk, Dan, 2023, In: Journal of Natural Products. 86, 4, p. 694–709

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Combined magnetic ligand fishing and high-resolution inhibition profiling for identification of α-glucosidase inhibitory ligands: A new screening approach based on complementary inhibition and affinity profiles.

    Wubshet, S. G., Liu, B., Kongstad, Kenneth Thermann, Böcker, U., Petersen, M. J., Li, T., Wang, J. & Stærk, Dan, 2019, In: Talanta. 200, p. 279-287

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Combined use of high-resolution α-glucosidase inhibition profiling and HPLC-HRMS-SPE-NMR for investigation of antidiabetic principles in crude plant extracts

    Kongstad, Kenneth Thermann, Özdemir, C., Barzak, A., Wubshet, S. G. & Stærk, Dan, 5 Feb 2015, In: Journal of Agricultural and Food Chemistry. 63, 8, p. 2257-2263 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Combining HPLC-PDA-MS-SPE-NMR with circular dichroism for complete natural product characterization in crude extracts: Levorotatory gossypol in Thespesia danis

    Sprogøe, K., Stærk, Dan, Ziegler, H. L., Jensen, T. H., Holm-Møller, S. B. & Jaroszewski, J. W., 2008, In: Journal of Natural Products. 71, 4, p. 516-519

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Combining PARAFAC analysis of HPLC-PDA profiles and structural characterization using HPLC-PDA-SPE-NMR-MS experiments: commercial preparations of St. John's Wort

    Schmidt, B., Jaroszewski, J. W., Bro, Rasmus, Witt, M. & Stærk, Dan, 2008, In: Analytical Chemistry. 80, 6, p. 1978-1987 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 1299056