Henrik Franzyk
Associate Professor
Iridoid Glucosides from Phlomis tuberosa L. and Phlomis herba-ventis L
Alipieva, K. I., Jensen, S. R., Franzyk, Henrik, Handjieva, N. V. & Evstatieva, L. N., 2000, In: Zeitschrift für Naturforschung C - A Journal of Biosciences. 55c, p. 137-140 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elucidating the nanostructure of small interfering RNA-loaded lipidoid-polymer hybrid nanoparticles
Aljabbari, Anas Samir Mohammad, Lokras, Abhijeet, Kirkensgaard, Jacob Judas Kain, Rades, Thomas, Franzyk, Henrik, Thakur, A., Zhang, Y. & Foged, Camilla, 2023, In: Journal of Colloid and Interface Science. 633, p. 907-922Research output: Contribution to journal › Journal article › Research › peer-review
- Published
C-locked analogs of the antimicrobial peptide BP214
Andersen, I. K. L., Thomsen, T. T., Rashid, J., Bobak, T. R., Oddo, A., Franzyk, Henrik, Løbner-Olesen, Anders & Hansen, Paul Robert, 2022, In: Antibiotics. 11, 8, 10 p., 1080.Research output: Contribution to journal › Journal article › Research › peer-review
- Submitted
Anchoring of hydrophilic coating polymers onto charged liposomes via attractive electrostatic interactions using charged tags to control the surface charge drainage properties and cellular targeting
Andersen, P. L., Christensen, D., Franzyk, Henrik, Foged, Camilla & Schmidt, S. T., 2018, (Submitted)Research output: Patent
- Published
Cell-penetrating antimicrobial peptides - prospectives for targeting intracellular infections
Bahnsen, J. S., Franzyk, Henrik, Sayers, E. J., Jones, A. T. & Nielsen, Hanne Mørck, 2015, In: Pharmaceutical Research. 32, 5, p. 1546-56 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The antimicrobial and cell-penetrating effects of the CPP penetratin and derived analogues.
Bahnsen, J. S., Franzyk, Henrik & Nielsen, Hanne Mørck, 2012.Research output: Contribution to conference › Poster › Research
- Published
Håb om at ramme latente bakterier i deres skjul
Bahnsen, J. S., Water, J. J., Foged, Camilla, Franzyk, Henrik & Nielsen, Hanne Mørck, 2012, In: Lægemiddelforskning 2012. 2012, p. 12-14Research output: Contribution to journal › Journal article › Research
- Published
Cell-penetrating Peptides Targeting Intracellular Infections
Bahnsen, J. S., Franzyk, Henrik, Sandberg-Schaal, A. & Nielsen, Hanne Mørck, 2013.Research output: Contribution to conference › Poster › Research › peer-review
- Published
Antimicrobial and cell-penetrating properties of penetratin analogs: effect of sequence and secondary structure
Bahnsen, J. S., Franzyk, Henrik, Sandberg-Schaal, A. & Nielsen, Hanne Mørck, 2013, In: B B A - Biomembranes. 1828, 2, p. 223-232 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Repurposing azithromycin and rifampicin against Gram-negative pathogens by combination with peptide potentiators
Baker, K. R., Jana, B., Hansen, A. M., Vissing, K. J., Nielsen, Hanne Mørck, Franzyk, Henrik & Guardabassi, Luca, 2019, In: International Journal of Antimicrobial Agents. 53, p. 868-872 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Repurposing Azithromycin and Rifampicin Against Gram-Negative Pathogens by Combination With Peptidomimetics
Baker, K. R., Jana, B., Hansen, A. M., Nielsen, Hanne Mørck, Franzyk, Henrik & Guardabassi, Luca, 2 Jul 2019, In: Frontiers in Cellular and Infection Microbiology. 9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A high-throughput approach to identify compounds that impair envelope integrity in Escherichia coli
Baker, K. R., Jana, B., Franzyk, Henrik & Guardabassi, Luca, Oct 2016, In: Antimicrobial Agents and Chemotherapy. 60, 10, p. 5995-6002 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An approach to identify clinically relevan, non-toxic peptide-antimicrobial combinations that eliminate intrinsic resistance in Gram-negative pathogens
Baker, K. R., Jana, B., Nielsen, Hanne Mørck, Franzyk, Henrik & Guardabassi, Luca, 2017. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Synergistic peptidomimetic-antimicrobial combinations to combat multidrug-resistant Gram-negative bacterial infections
Baker, K. R., Jana, B., Franzyk, Henrik & Guardabassi, Luca, 2017. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Breaching bacterial barricades: A high-throughput approach to identify compounds targeting envelope integrity
Baker, K. R., Jana, B., Franzyk, Henrik & Guardabassi, Luca, 2016. 1 p.Research output: Contribution to conference › Poster › Research
- Published
The agr inhibitors solonamide B and analogues alter immune responses to Staphylococccus aureus but do not exhibit adverse effects on immune cell functions
Baldry, M., Kitir, B., Frøkiær, Hanne, Christensen, S. B., Taverne, N., Meijerink, M., Franzyk, Henrik, Olsen, Christian Adam, Wells, J. M. & Ingmer, Hanne, 2016, In: P L o S One. 11, 1, 17 p., e0145618.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fluorophore labeling of a cell-penetrating peptide induces differential effects on its cellular distribution and affects cell viability
Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2017, In: B B A - Biomembranes. 1859, 12, p. 2483-2494Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stereoisomer-Dependent Membrane Association and Capacity for Insulin Delivery Facilitated by Penetratin
Birch, D., Sayers, E. J., Christensen, M. V., Jones, A. T., Franzyk, Henrik & Nielsen, Hanne Mørck, 2023, In: Pharmaceutics. 15, 6, 15 p., 1672.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative study of the drug delivery mechanism of L-penetratin and D-penetratin
Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2018.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Stereochemistry as a determining factor for the effect of a cell-penetrating peptide on cellular viability and epithelial integrity
Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 24 May 2018, In: Biochemical Journal. 475, 10, p. 1773-1788 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intact penetratin metabolite permeates across Caco-2 monolayers
Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2015.Research output: Contribution to conference › Poster › Research
- Published
Incorporation of the crossfire Beilstein database into the organic chemistry curriculum at the Royal Danish School of Pharmacy
Christensen, Søren Brøgger, Franzyk, Henrik, Frølund, Bente, Jaroszewski, J. W., Stærk, Dan & Vedsø, P., 1 Jun 2002, In: Journal of Chemical Education. 79, 6, 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cyclopentanoid cyanohydrin glucosides from Passiflora mixta
Bylov, T., Franzyk, Henrik & Jaroszewski, J. W., 2004, In: Biochemical Systematics and Ecology. 32, p. 695-698 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
19F-substituted amino acids as an alternative to fluorophore labels: monitoring of degradation and cellular uptake of analogues of penetratin by 19F NMR
Christensen, M. V., Kongstad, Kenneth Thermann, Sondergaard, T. E., Stærk, Dan, Nielsen, Hanne Mørck, Franzyk, Henrik & Wimmer, R., 2019, In: Journal of Biomolecular N M R. 73, p. 167-182Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On-resin N-formylation of peptides: a head-to-head comparison of reagents in solid-phase synthesis of ligands for formyl peptide receptors
Christensen, S. B., Hansen, A. M. & Franzyk, Henrik, 2017, In: Journal of Peptide Science. 23, 5, p. 410-415 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incorporation of the Cross Fire Beilstein database in the organic chemistry curriculum at the Royal Danish School of Pharmacy
Christensen, Søren Brøgger, Franzyk, Henrik, Frølund, Bente, Jaroszewski, J. W., Stærk, Dan & Vedsø, P., 2002, In: Journal of Chemical Education. 79, p. 765-768Research output: Contribution to journal › Journal article › Research
- Published
Improved in vitro evaluation of novel antimicrobials: potential synergy between human plasma and antibacterial peptidomimetics, AMPs, or antibiotics against human pathogenic bacteria
Citterio, L., Franzyk, Henrik, Palarasah, Y., Andersen, T. E., Mateiu, R. V. & Gram, L., Feb 2016, In: Research in Microbiology. 167, 2, p. 72-82 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human plasma potentiates antibacterial effect of peptidomimetics against Gram-negative and Gram-positive pathogenic bacteria
Citterio, L., A, K., K, H., Franzyk, Henrik & Gram, L., 2014.Research output: Contribution to conference › Poster › Research
- Published
Solid-phase route to Fmoc-protected cationic amino acid building blocks
Clausen, J. D., Linderoth, L., Nielsen, Hanne Mørck & Franzyk, Henrik, 2012, In: Amino Acids. 43, 4, p. 1633-41 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of antibacterial activity (in vitro and in vivo) and mode of action for des-acyl tridecaptins (DATs)
Couturier, C., Ronzon, Q., Lattanzi, G., Lingard, I., Coyne, S., Cazals, V., Dubarry, N., Yvon, S., Leroi-Geissler, C., Gracia, O. R., Teague, J., Sordello, S., Corbett, D., Bauch, C., Monlong, C., Payne, L., Taillier, T., Fuchs, H., Broenstrup, M., Harrison, P. H. & 10 others, , 2024, In: European Journal of Medicinal Chemistry. 265, 20 p., 116097.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microwave-assisted ring-opening of activated aziridines with resin-bound amines
Crestey, F., Witt, M., Frydenvang, Karla Andrea, Stærk, Dan, Jaroszewski, J. W. & Franzyk, Henrik, 2008, In: Journal of Organic Chemistry. 73, 9, p. 3566-3569 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expedite Protocol for Construction of Chiral Regioselectively N-Protected Monosubstituted Piperazine, 1,4-Diazepane, and 1,4-Diazocane Building Blocks
Crestey, F., Witt, M., Jaroszewski, J. W. & Franzyk, Henrik, 11 Jun 2009, In: Journal of Organic Chemistry. 74, 15, p. 5652-5655Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficient loading of primary alcohols onto a solid phase using a trityl bromide linker
Crestey, F., Ottesen, L. K., Jaroszewski, J. W. & Franzyk, Henrik, 2008, In: Tetrahedron Letters. 49, 41, p. 5890-5893Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies towards improved cell-penetrating peptide-promoted macromolecular drug delivery
Dahlqvist Clausen, J. A., Linderoth, L., Andersen, R. B., Franzyk, Henrik & Nielsen, Hanne Mørck, 2010, In: Drug Discovery Today. 15, 23-24, p. 1109 1 p., A81.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Studies towards improved stability and permeability of a cell-penetrating peptide
Dahlqvist Clausen, J. A., Linderoth, L., Andersen, R. B., Franzyk, Henrik & Nielsen, Hanne Mørck, 2010, In: Journal of Peptide Science. 16, p. 148 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
Fontanesioside and 5-Hydroxysecologanol from Fontanesia phillyreoides.
Damtoft, S., Franzyk, Henrik & Jensen, S. R., 1994, In: Phytochemistry. 35, p. 705-711 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Biosynthesis of Iridoids in Syringa and Fraxinus: Secoiridoid Precursors
Damtoft, S., Franzyk, Henrik & Jensen, S. R., 1995, In: Phytochemistry. 40, p. 773-784 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Biosynthesis of Iridoids in Syringa and Fraxinus: Carbocyclic Iridoid Precursors
Damtoft, S., Franzyk, Henrik & Jensen, S. R., 1995, In: Phytochemistry. 40, p. 785-792 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Biosynthesis of Iridoids in Forsythia spp.
Damtoft, S., Franzyk, Henrik & Jensen, S. R., 1994, In: Phytochemistry. 37, p. 173-178 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Biosynthesis of Secoiridoids in Fontanesia
Damtoft, S., Franzyk, Henrik & Jensen, S. R., 1994, In: Phytochemistry. 38, p. 615-621 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Iridoid Glucosides from Picconia excelsa
Damtoft, S., Franzyk, Henrik & Jensen, S. R., 1997, In: Phytochemistry. 45, p. 743-750 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of Factors of Importance for Spray Drying of Small Interfering RNA-Loaded Lipidoid-Polymer Hybrid Nanoparticles for Inhalation
Dormenval, C., Lokras, Abhijeet, Cano-Garcia, G., Wadhwa, A., Thanki, K., Rose, F., Thakur, A., Franzyk, Henrik & Foged, Camilla, 2019, In: Pharmaceutical Research. 36, 10, 142.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthesis and Characterisation of an Array of Lipidoid Analogues for RNA Interference Therapy
Falkenberg, E., de Groot, A. M., Sijts, A. J. A. M., Thanki, K., Zeng, X., Nielsen, Hanne Mørck, Franzyk, Henrik & Foged, Camilla, 2017.Research output: Contribution to conference › Poster › Research
- Published
Philanthotoxin-343 attenuates retinal and optic nerve injury, and protects visual function in rats with N-methyl-D-aspartate-induced excitotoxicity
Fazel, M. F., Abu, I. F., Mohamad, M. H. N., Agarwal, R., Iezhitsa, I., Bakar, N. S., Juliana, N., Mellor, I. R. & Franzyk, Henrik, 2020, In: PLoS ONE. 15, 7, 14 p., e0236450.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nanoparticle compositions comprising PLGA derivatives and a lipid for delivery of drugs, in particular nucleic acids, especially siRNA
Foged, Camilla, Franzyk, Henrik, Zeng, X., Nielsen, Hanne Mørck & Thanki, K., 21 Sep 2017, IPC No. A61K31/713, A61K47/18, A61K47/34, A61K9/51, A61P25/00, A61P29/00, A61P35/00, Patent No. WO2017158093-A1, 16 Mar 2017, Priority date 17 Mar 2016, Priority No. EP 2016-160931Research output: Patent
- Published
Cellular uptake and membrane-destabilising properties of a-peptide/ß-peptoid chimeras: lessons for the design of new cell-penetrating peptides
Foged, Camilla, Franzyk, Henrik, Bahrami, S., Frøkjær, Sven, Jaroszewski, J. W., Nielsen, Hanne Mørck & Olsen, Christian Adam, 2008, In: BBA General Subjects. 1778, 11, p. 2487-2495Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microwave-Assisted Ring-Opening of Activated Aziridines with Resin-Bound Amines
Franzyk, Henrik, Crestey, F., Witt, M., Frydenvang, Karla Andrea, Stærk, Dan & Jaroszewski, J., 2008, In: Synfacts. 7, p. 769Research output: Contribution to journal › Journal article › Research › peer-review
Constrained Glycopeptide Ligands for MPRs. Limitations of Unprotected Phosphorylated Building Blocks
Franzyk, Henrik, Christensen, M. K., Jørgensen, R. M., Meldal, M., Cordes, H., Mouritsen, S. & Bock, K., 1997, In: Bioorganic and Medicinal Chemistry. 5, p. 21-40 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ØVELSESVEJLEDNING TIL: Øvelsesdelen af Biopharmaceuticals: Bioorganisk Kemi
Franzyk, Henrik, 15 Aug 2016, Dept. Drug Design and Pharmacology. 60 p.Research output: Book/Report › Compendium/lecture notes › Education
- Published
Vejledning til Praktisk Udførelse af Øvelsesdelen i Kurset Biopharmaceuticals: Bioorganisk Kemi 2018
Franzyk, Henrik, 2018, 66 p.Research output: Book/Report › Compendium/lecture notes › Education
ID: 1302063
Most downloads
-
1999
downloads
Erythrocyte membrane modifying agents and the inhibition of Plasmodium falciparum growth: structure-activity relationships for betulinic acid analogues
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
1599
downloads
Prolonged Shelf Life in Fermented Milk Products Investigated by Bioassay-Guided Chemometrics
Research output: Contribution to conference › Poster › Research
Published -
1278
downloads
Non-natural Amino Acid and Peptoid Building Blocks for Optimization of the Cell-Penetrating (R-X-R)n Motif
Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Published