Henrik Franzyk

Henrik Franzyk

Associate Professor

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    ORCID: 0000-0002-2822-1927

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    1. Published

      Øvelsesvejledning til bioorganisk kemi: øvelser M23-2

      Franzyk, Henrik, 2007, Københavns Universitet, Det Farmaceutiske Fakultet, Institut for Medicinalkemi.

      Research output: Book/Report › Compendium/lecture notes › Education

    2. Iridoids and Verbascosides in Retzia

      Damtoft, S., Franzyk, H., Jensen, S. R. & Nielsen B.J., D. S. ,. F. H. ,. J. S. R. &. N. B. J., 1993, In: Phytochemistry. 34, p. 239-243

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Synthetic aspects of iridoid chemistry

      Franzyk, Henrik, 2000, In: Fortschritte der Chemie Organischer Naturstoffe. 79, p. 1-114 114 p.

      Research output: Contribution to journal › Review › Research

    4. Synthesis of Carbocyclic Homo-N-nucleosides from Iridoids

      Franzyk, Henrik, Rasmussen, J. H., Mazzei, R. A. & Jensen, S. R., 1998, In: European Journal of Organic Chemistry. p. 2931-2935 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Noter til BIOPHARMACEUTICALS: BIOORGANISK KEMI

      Franzyk, Henrik & Nielsen, Peter E., 15 Aug 2016, Dept. Drug Design and Pharmacology. 159 p.

      Research output: Book/Report › Compendium/lecture notes › Education

    6. Published

      Biopolymer-based nanogels improve the safety profile and antimicrobial activity of a lysine-based peptidomimetic.

      Franzyk, Henrik, 2017.

      Research output: Contribution to conference › Poster › Research › peer-review

    7. Ozonolysis of Protected Iridoid Glucosides

      Franzyk, Henrik, Rasmussen, J. H. & Jensen, S. R., 1998, In: European Journal of Organic Chemistry. p. 365-370 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Stereoselective Hydrogenation and Ozonolysis of Iridoids. Conversion into Carbocyclic Nucleoside Analogues

      Franzyk, Henrik & Stermitz, F. R., 1999, In: Journal of Natural Products. 62, p. 1646-1654 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      ØVELSESVEJLEDNING TIL: Øvelsesdelen af Biopharmaceuticals: Bioorganisk Kemi

      Franzyk, Henrik, 15 Aug 2016, Dept. Drug Design and Pharmacology. 60 p.

      Research output: Book/Report › Compendium/lecture notes › Education

    10. Published

      Vejledning til Praktisk Udførelse af Øvelsesdelen i Kurset Biopharmaceuticals: Bioorganisk Kemi 2018

      Franzyk, Henrik, 2018, 66 p.

      Research output: Book/Report › Compendium/lecture notes › Education

    11. Published

      Peptide/β-Peptoid Hybrids with Ultrashort PEG-Like Moieties: Effects on Hydrophobicity, Antibacterial Activity and Hemolytic Properties

      Frederiksen, N., Louka, S., Mudaliar, C., Domraceva, I., Kreicberga, A., Pugovics, O., Żabicka, D., Tomczak, M., Wygoda, W., Björkling, Fredrik & Franzyk, Henrik, 2021, In: International Journal of Molecular Sciences. 22, 13, 17 p., 7041.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Alternating Cationic-Hydrophobic Peptide/Peptoid Hybrids: Influence of Hydrophobicity on Antibacterial Activity and Cell Selectivity

      Frederiksen, N., Hansen, Paul Robert, Zabicka, D., Tomczak, M., Urbas, M., Domraceva, I., Björkling, Fredrik & Franzyk, Henrik, 2020, In: ChemMedChem. 15, 24, p. 2544-2561

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Peptide/Peptoid Hybrid Oligomers: The Influence of Hydrophobicity and Relative Side-Chain Length on Antibacterial Activity and Cell Selectivity

      Frederiksen, N., Hansen, Paul Robert, Björkling, Fredrik & Franzyk, Henrik, 4 Dec 2019, In: Molecules (Print Archive Edition). 24, 18 p., 4429.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Structure-Activity Study of alpha-Peptoid/alpha-Peptide Peptidomimetics: Influence of Hydrophobicity on Antimicrobial Activity and Cytotoxicity

      Frederiksen, N., Bjorkling, F., Nielsen, P. & Franzyk, Henrik, Sep 2018, In: Journal of Peptide Science. 24, s2, p. S120-S120

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    15. Published

      Assessment of structurally diverse philanthotoxin analogues for inhibitory activity on ionotropic glutamate receptor subtypes: Discovery of nanomolar, nonselective, and use-dependent antagonists

      Frølund, S., Bella, A., Kristensen, Anders Skov, Ziegler, H. L., Witt, M., Olsen, C. A., Strømgaard, Kristian, Franzyk, Henrik & Jaroszewski, J. W., 2010, In: Journal of Medicinal Chemistry. 53, 20, p. 7441-7451

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Electrophysiological characterization of analogues of philanthotoxin-343 on ionotropic glutamate receptors

      Frølund, S. U., Ziegler, H. L., Franzyk, Henrik, Strømgaard, Kristian, Kristensen, Anders Skov & Jaroszewski, J. W., 2008.

      Research output: Contribution to conference › Poster › Research

    17. Published

      Highly cationic cell-penetrating peptides affect the barrier integrity and facilitates mannitol permeation in a human stem cell-based blood-brain barrier model

      Frøslev, Patrick, Franzyk, Henrik, Ozgür, Burak, Larsen, Birger Brodin & Kristensen, Mie, 2022, In: European Journal of Pharmaceutical Sciences. 168, 10 p., 106054.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Facile Preparation of PNA-Peptide Conjugates with a Polar Maleimide-Thioether Linkage

      Hansen, A. M., Shaikh, Ashif Yasin & Franzyk, Henrik, 2020, Peptide Nucleic Acids: Methods and Protocols. P. E. N. (ed.). Humana Press, p. 97-118 22 p. (Methods in molecular biology (Clifton, N.J.), Vol. 2105).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    19. Published

      Microwave-assisted solid-phase synthesis of antisense acpP peptide nucleic acid-peptide conjugates active against colistin- and tigecycline-resistant E. coli and K. pneumoniae

      Hansen, A. M., Bonke, G., Hogendorf, W. F. J., Björkling, Fredrik, Nielsen, J., Kongstad, Kenneth Thermann, Zabicka, D., Tomczak, M., Urbas, M., Nielsen, Peter E. & Franzyk, Henrik, 2019, In: European Journal of Medicinal Chemistry. 168, p. 134-145 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Lactam hybrid analogues of solonamide B and autoinducing peptides as potent S. aureus AgrC antagonists

      Hansen, A. M., Peng, P., Baldry, M., Perez-Gassol, I., Christensen, S. B., Vinther, J. M., Ingmer, Hanne & Franzyk, Henrik, 2018, In: European Journal of Medicinal Chemistry. 152, p. 370-376 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Antibacterial Peptide Nucleic Acid-Antimicrobial Peptide (PNA-AMP) Conjugates: Antisense Targeting of Fatty Acid Biosynthesis

      Hansen, A. M., Bonke, G., Larsen, C. J., Yavari, Niloofar, Nielsen, Peter E. & Franzyk, Henrik, 2016, In: Bioconjugate Chemistry. 27, 4, p. 863-867 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Studies on acid stability and solid-phase block synthesis of peptide-peptoid hybrids: ligands for formyl peptide receptors

      Hansen, A. M., Skovbakke, S. L., Christensen, S. B., Perez-Gassol, I. & Franzyk, Henrik, 2019, In: Amino Acids. 51, p. 205-218

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Macrophage phosphoproteome analysis reveals MINCLE-dependent and -independent mycobacterial cord factor signaling

      Hansen, M., Peltier, J., Killy, B., Amin, B., Bodendorfer, B., Härtlova, A., Uebel, S., Bosmann, M., Hofmann, J., Büttner, C., Ekici, A. B., Kuttke, M., Franzyk, Henrik, Foged, Camilla, Beer-Hammer, S., Schabbauer, G., Trost, M. & Lang, R., Apr 2019, In: Molecular and Cellular Proteomics. 18, 4, p. 669-685

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Fluorophore labeling of a cell-penetrating peptide significantly alters the mode and degree of biomembrane interaction

      Hedegaard, S. F., Derbas, M. S., Lind, T. K., Kasimova, M. R., Christensen, M. V., Michaelsen, M. H., Campbell, R. A., Jørgensen, Lene, Franzyk, Henrik, Cárdenas, M. & Nielsen, Hanne Mørck, 2018, In: Scientific Reports. 8, 1, 14 p., 6327.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Selectivity in the potentiation of antibacterial activity of α-peptide/β-peptoid peptidomimetics and antimicrobial peptides by human blood plasma

      Hein-Kristensen, L., Knapp, K. M., Franzyk, Henrik & Gram, L., 27 Aug 2013, In: Research in Microbiology. 164, 9, p. 933-940 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 1302063