Henrik Franzyk

Henrik Franzyk

Associate Professor

Member of:

    ORCID: 0000-0002-2822-1927

    Publication year:
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    101 - 200 out of 274Page size: 100
    1. 2017
    2. Published

      Synergistic peptidomimetic-antimicrobial combinations to combat multidrug-resistant Gram-negative bacterial infections

      Baker, K. R., Jana, B., Franzyk, Henrik & Guardabassi, Luca, 2017. 1 p.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    3. Published

      Synthesis and Characterisation of an Array of Lipidoid Analogues for RNA Interference Therapy

      Falkenberg, E., de Groot, A. M., Sijts, A. J. A. M., Thanki, K., Zeng, X., Nielsen, Hanne Mørck, Franzyk, Henrik & Foged, Camilla, 2017.

      Research output: Contribution to conference › Poster › Research

    4. 2016
    5. Published

      Block of nicotinic acetylcholine receptors by philanthotoxins is strongly dependent on their subunit composition

      Kachel, H. S., Patel, R. N., Franzyk, Henrik & Mellor, I. R., 30 Nov 2016, In: Scientific Reports. 6, p. 1-13 13 p., 38116.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Conserved molecular superlattices in a series of homologous synthetic mycobacterial cell-wall lipids forming interdigitated bilayers

      Martin-Bertelsen, Birte, Yaghmur, Anan, Franzyk, Henrik, Justesen, S., Kirkensgaard, Jacob Judas Kain & Foged, Camilla, 7 Nov 2016, In: Langmuir. 32, 48, p. 12693–12701 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      A high-throughput approach to identify compounds that impair envelope integrity in Escherichia coli

      Baker, K. R., Jana, B., Franzyk, Henrik & Guardabassi, Luca, Oct 2016, In: Antimicrobial Agents and Chemotherapy. 60, 10, p. 5995-6002 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      The peptidomimetic Lau-(Lys-βNSpe)6-NH2 antagonizes formyl peptide receptor 2 expressed in mouse neutrophils

      Skovbakke, S. L., Winther, M., Gabl, M., Holdfeldt, A., Linden, S., Wang, J. M., Dahlgren, C., Franzyk, Henrik & Forsman, H., 8 Sep 2016, In: Biochemical Pharmacology. 119, p. 56-65 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Noter til BIOPHARMACEUTICALS: BIOORGANISK KEMI

      Franzyk, Henrik & Nielsen, Peter E., 15 Aug 2016, Dept. Drug Design and Pharmacology. 159 p.

      Research output: Book/Report › Compendium/lecture notes › Education

    10. Published

      ØVELSESVEJLEDNING TIL: Øvelsesdelen af Biopharmaceuticals: Bioorganisk Kemi

      Franzyk, Henrik, 15 Aug 2016, Dept. Drug Design and Pharmacology. 60 p.

      Research output: Book/Report › Compendium/lecture notes › Education

    11. Published

      Trehalose diester glycolipids are superior to the monoesters in binding to Mincle, activation of macrophages invitro and adjuvant activity invivo

      Huber, A., Kallerup, R. S., Korsholm, K. S., Franzyk, Henrik, Lepenies, B., Christensen, D., Foged, Camilla & Lang, R., Aug 2016, In: Innate Immunity. 22, 6, p. 405-418 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Delivery of siRNA Complexed with Palmitoylated α-Peptide/β-Peptoid Cell-Penetrating Peptidomimetics: Membrane Interaction and Structural Characterization of a Lipid-Based Nanocarrier System.

      Jing, X., Foged, Camilla, Martin-Bertelsen, Birte, Yaghmur, Anan, Knapp, K. M., Malmsten, M., Franzyk, Henrik & Nielsen, Hanne Mørck, 6 Jun 2016, In: Molecular Pharmaceutics. 13, 6, p. 1739-1749 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Improved in vitro evaluation of novel antimicrobials: potential synergy between human plasma and antibacterial peptidomimetics, AMPs, or antibiotics against human pathogenic bacteria

      Citterio, L., Franzyk, Henrik, Palarasah, Y., Andersen, T. E., Mateiu, R. V. & Gram, L., Feb 2016, In: Research in Microbiology. 167, 2, p. 72-82 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      An amphipathic undecapeptide with all D-amino acids shows promising activity against colistin-resistant strains of Acinetobacter baumannii and a dual mode of action

      Oddo, A., Thomsen, T. T., Kjelstrup, S., Gorey, C., Franzyk, Henrik, Frimodt-Møller, N., Løbner-Olesen, Anders & Hansen, Paul Robert, 2016, In: Antimicrobial Agents and Chemotherapy. 60, 1, p. 592-599 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Antibacterial Peptide Nucleic Acid-Antimicrobial Peptide (PNA-AMP) Conjugates: Antisense Targeting of Fatty Acid Biosynthesis

      Hansen, A. M., Bonke, G., Larsen, C. J., Yavari, Niloofar, Nielsen, Peter E. & Franzyk, Henrik, 2016, In: Bioconjugate Chemistry. 27, 4, p. 863-867 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Breaching bacterial barricades: A high-throughput approach to identify compounds targeting envelope integrity

      Baker, K. R., Jana, B., Franzyk, Henrik & Guardabassi, Luca, 2016. 1 p.

      Research output: Contribution to conference › Poster › Research

    17. Published

      Efficient Pulmonary Delivery of siRNA Using Lipid-Polymer Hybrid Nanoparticles (LPNs): Insights into Formulation, Transfection and In Vivo Biodistribution Using NIR-based Spatio-Temporal Tracking.

      Thanki, K., Geyer, A., Zeng, X., Sami, H., Gehrig, S., Justesen, S., Franzyk, Henrik, Ogris, M., Nielsen, Hanne Mørck & Foged, Camilla, 2016.

      Research output: Contribution to conference › Poster › Research

    18. Published

      Iminolactones as Tools for Inversion of the Absolute Configuration of alpha-Amino Acids and as Inhibitors of Cancer Cell Proliferation

      Jensen, C. M., Chow, H., Chen, M., Zhai, L., Frydenvang, Karla Andrea, Liu, H., Franzyk, Henrik & Christensen, Søren Brøgger, 2016, In: European Journal of Medicinal Chemistry. 114, p. 118-133 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Nano-self-assemblies based on synthetic analogues of mycobacterial monomycoloyl glycerol and DDA: Supramolecular structure and adjuvant efficacy

      Martin-Bertelsen, Birte, Korsholm, K. S., Christensen, D., Franzyk, Henrik, Yaghmur, Anan & Foged, Camilla, 2016, In: Molecular Pharmaceutics. 13, 8, p. 2771-2781 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Peptidomimetics as novel formyl peptide receptor 2 (FPR2) modulators in human and mouse neutrophils

      Holdfeldt, A., Dahlgren, C., Forsman, H., Skovbakke, S. L. & Franzyk, Henrik, 2016.

      Research output: Contribution to conference › Poster › Research

    21. Published

      Roles of hydrophobicity, fluorination and distribution of cationic residues in α-peptide/β-peptoids for antibacterial and hemolytic properties

      Molchanova, N., Hansen, Paul Robert, Damborg, Peter Panduro & Franzyk, Henrik, 2016. 1 p.

      Research output: Contribution to conference › Poster › Research

    22. Published

      Soft hydrogels interpenetrating silicone – a polymer network for drug releasing medical devices

      Steffensen, S. L., Merete H., V., Møller, E. H., Jensen, M. G., Alm, M., Franzyk, Henrik & Nielsen, Hanne Mørck, 2016, In: Journal of Biomedical Materials Research. Part B: Applied Biomaterials. 104, 2, p. 402-410 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      The agr inhibitors solonamide B and analogues alter immune responses to Staphylococccus aureus but do not exhibit adverse effects on immune cell functions

      Baldry, M., Kitir, B., Frøkiær, Hanne, Christensen, S. B., Taverne, N., Meijerink, M., Franzyk, Henrik, Olsen, Christian Adam, Wells, J. M. & Ingmer, Hanne, 2016, In: P L o S One. 11, 1, 17 p., e0145618.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      The Lipidated Peptidomimetic Lau-((S)-Aoc)-(Lys-βNphe)6-NH2Is a Novel Formyl Peptide Receptor 2 Agonist That Activates Both Human and Mouse Neutrophil NADPH Oxidase

      Holdfeldt, A., Skovbakke, S. L., Winther, M., Gabl, M., Nielsen, C., Perez-Gassol, I., Larsen, C. J., Wang, J. M., Karlsson, A., Dahlgren, C., Forsman, H. & Franzyk, Henrik, 2016, In: Journal of Biological Chemistry. 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      The lipidated peptidomimetic Lau-[(S)-Aoc]-(Lys-βNphe)6-NH2 is a novel formyl peptide receptor 2 agonist that activates both human and mouse neutrophil NADPH-oxidase

      Holdfeldt, A., Skovbakke, S. L., Winther, M., Gabl, M., Nielsen, C., Perez-Gassol, I., Larsen, C. J., Wang, J. M., Karlsson, A., Dahlgren, C., Forsman, H. & Franzyk, Henrik, 2016, In: Journal of Biological Chemistry. 291, 38, p. 19888-19899 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. 2015
    27. Published

      Hyaluronic Acid-Based Nanogels Produced by Microfluidics-Facilitated Self-Assembly Improves the Safety Profile of the Cationic Host Defense Peptide Novicidin

      Water, J. J., Kim, Y., Maltesen, M. J., Franzyk, Henrik, Foged, Camilla & Nielsen, Hanne Mørck, Aug 2015, In: Pharmaceutical Research. 32, 8, p. 2727-35 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Conjugation of a cell-penetrating peptide to parathyroid hormone affects its structure, potency, and transepithelial permeation

      Kristensen, Mie, de Groot, A. M., Berthelsen, J., Franzyk, Henrik, Sijts, A. & Nielsen, Hanne Mørck, 18 Mar 2015, In: Bioconjugate Chemistry. 26, p. 477-488 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Nanoparticle-mediated delivery of the antimicrobial peptide plectasin against Staphylococcus aureus in infected epithelial cells

      Water, J. J., Smart, S., Franzyk, Henrik, Foged, Camilla & Nielsen, Hanne Mørck, 18 Feb 2015, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 92, p. 65-73 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      End Group Modification: Efficient Tool for Improving Activity of Antimicrobial Peptide Analogues towards Gram-Positive Bacteria

      Jahnsen, R. O., Sandberg-Schaal, A., Frimodt-Møller, N., Nielsen, Hanne Mørck & Franzyk, Henrik, 23 Jan 2015, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 95, Part A, p. 40–46 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      A palmitoylated α-peptide/β-peptoid host defense peptide mimetic with potent anti-inflammatory activity

      Skovbakke, S. L., Heegaard, P. M. H., Forsman, H., Dahlgren, C. & Franzyk, Henrik, 2015.

      Research output: Contribution to conference › Poster › Research › peer-review

    32. Published

      Antifungal properties of peptidomimetics with an arginine-[β-(2,5,7-tri-tert-butylindol-3-yl)alanine]-arginine motif against Saccharomyces cerevisiae and Zygosaccharomyces bailii

      Larsen, C. E., Larsen, C. J., Franzyk, Henrik & Regenberg, Birgitte, 2015, In: F E M S Yeast Research. 15, 3, 8 p., fov011.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Biophysical and nanostructural properties of trehalose 6-mono and 6,6’-diesters

      Madsen, C. M., Martin-Bertelsen, Birte, Kallerup, R. S., Rose, F., Christensen, D., Yaghmur, Anan, Franzyk, Henrik & Foged, Camilla, 2015. 1 p.

      Research output: Contribution to conference › Poster › Research

    34. Published

      Cell-penetrating antimicrobial peptides - prospectives for targeting intracellular infections

      Bahnsen, J. S., Franzyk, Henrik, Sayers, E. J., Jones, A. T. & Nielsen, Hanne Mørck, 2015, In: Pharmaceutical Research. 32, 5, p. 1546-56 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Influence of trehalose 6,6'-diester (TDX) chain length on the physicochemical and immunopotentiating properties of DDA/TDX liposomes

      Kallerup, R. S., Madsen, C. M., Schiøth, M. L., Franzyk, Henrik, Rose, F., Christensen, D., Korsholm, K. S. & Foged, Camilla, 2015, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 90, p. 80-89 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Intact penetratin metabolite permeates across Caco-2 monolayers

      Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2015.

      Research output: Contribution to conference › Poster › Research

    37. Published

      Jagten på kongens efterfølger

      Franzyk, Henrik, Björkling, Fredrik, Nielsen, J. & Nielsen, Peter E., 2015, In: Lægemiddelforskning. 2015, p. 24-27 4 p.

      Research output: Contribution to journal › Journal article › Communication

    38. Published

      Lipidated α-Peptide/β-Peptoid Hybrids with Potent Anti-inflammatory Activity

      Skovbakke, S. L., Larsen, C. J., Heegaard, P. M. H., Moesby, L. & Franzyk, Henrik, 2015, In: Journal of Medicinal Chemistry. 58, 2, p. 801-813 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Penetratin-Mediated Transepithelial Insulin Permeation: Importance of Cationic Residues and pH for Complexation and Permeation

      Kristensen, Mie, Franzyk, Henrik, Klausen, M. T., Iversen, A., Bahnsen, J. S., Skyggebjerg, R. B., Foderà, Vito & Nielsen, Hanne Mørck, 2015, In: A A P S Journal. 17, 5, p. 1200-1209 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Structure-Activity Relationship Study of Lysine-Based Antimicrobial α-Peptide/β-Peptoid Oligomers

      Molchanova, N., Hansen, Paul Robert & Franzyk, Henrik, 2015.

      Research output: Contribution to conference › Poster › Research

    41. Published

      Surface coating of siRNA-peptidomimetic nano-self-assemblies with anionic lipid bilayers: Enhanced gene silencing and reduced adversed effects in vitro

      Zeng, X., de Groot, A. M., Sijts, A., Blenke, E. O., Colombo, S., van Eden, W., Franzyk, Henrik, Nielsen, Hanne Mørck & Foged, Camilla, 2015, In: Nanoscale. 7, 46, p. 19687-19698 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Sustained prevention of biofilm formation on a novel silicone matrix suitable for medical devices

      Steffensen, S. L., Merete H., V., Jensen, M. G., Alm, M., Franzyk, Henrik & Nielsen, Hanne Mørck, 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 94, p. 305-311

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      The Proteolytically Stable Peptidomimetic Pam-(Lys-βNSpe)6-NH2 Selectively Inhibits Human Neutrophil Activation via Formyl Peptide Receptor 2

      Skovbakke, S. L., Heegaard, P. M. H., Larsen, C. J., Franzyk, Henrik, Forsman, H. & Dahlgren, C., 2015, In: Biochemical Pharmacology. 93, 2, p. 182-195 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. 2014
    45. Published

      Critical role of a conserved transmembrane lysine in substrate recognition by the proton-coupled oligopeptide transporter YjdL

      Jensen, J. M., Aduri, N. G., Prabhala, B. K., Jahnsen, R., Franzyk, Henrik & Mirza, Osman Asghar, 24 Sep 2014, In: International Journal of Biochemistry & Cell Biology. 55, p. 311-17 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      The Effects of Conformational Constraints in the Polyamine Moiety of Philanthotoxins on AMPAR Inhibition

      Franzyk, Henrik, Grzeskowiak, J. W., Tikhonov, D. B., Jaroszewski, J. W. & Mellor, I. R., Aug 2014, In: ChemMedChem. 9, 8, p. 1725-31 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Quantification of pharmaceutical peptides using selenium as an elemental detection label

      Møller, L. H., Gabel-Jensen, C., Franzyk, Henrik, Bahnsen, J. S., Stürup, Stefan & Gammelgaard, Bente, 16 Jul 2014, In: Metallomics : integrated biometal science. 6, p. 1639-1647 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Tailoring Cytotoxicity of Antimicrobial Peptidomimetics with High Activity against Multidrug-Resistant Escherichia coli

      Jahnsen, R. D., Sandberg-Schaal, A., Vissing, K. J., Nielsen, Hanne Mørck, Frimodt-Møller, N. & Franzyk, Henrik, 20 Mar 2014, In: Journal of Medicinal Chemistry. 57, 7, p. 2864-2873

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Subunit-Dependent Inhibition of Neuronal Nicotinic Acetylcholine Receptors by Philanthotoxins

      Kachel, H. S., Franzyk, Henrik, Strømgaard, Kristian, Tikhonov, D. B. & Mellor, I. R., 28 Jan 2014, In: Biophysical Society. Annual Meeting. Abstracts. 106, 2, p. 338A-338A 1 p.

      Research output: Contribution to journal › Journal article › Research

    50. Published

      Does the molecular structure of mono and diester analogues of trehalose-6,6’-dibehenate (TDB) influence the biophysical chracteristics and receptor interaction with Mincle ?

      Kallerup, R. S., Martin-Bertelsen, Birte, Franzyk, Henrik, Korsholm, K. S., Huber, A., Lang, R. & Foged, Camilla, 2014. 1 p.

      Research output: Contribution to conference › Poster › Research

    51. Published

      Human plasma potentiates antibacterial effect of peptidomimetics against Gram-negative and Gram-positive pathogenic bacteria

      Citterio, L., A, K., K, H., Franzyk, Henrik & Gram, L., 2014.

      Research output: Contribution to conference › Poster › Research

    52. Published

      Improving the safety profile of an antimicrobial peptide: Self-assembly into hydrogel nanoparticles using microfluidics

      Water, J. J., Maltesen, M. J., Foged, Camilla, Franzyk, Henrik & Nielsen, Hanne Mørck, 2014.

      Research output: Contribution to conference › Poster › Research › peer-review

    53. Published

      Prolonged Shelf Life in Fermented Milk Products Investigated by Bioassay-Guided Chemometrics

      Vinther, J. M., Garrigues, C., Nyberg, N., Jäger, A., Franzyk, Henrik & Stærk, Dan, 2014.

      Research output: Contribution to conference › Poster › Research

    54. Published

      Silicone embedded nanogels for prolonged resistance against biofilm formation

      Steffensen, S. L., Vestergaard, M. H., Jensen, M. G., Alm, M., Franzyk, Henrik & Nielsen, Hanne Mørck, 2014.

      Research output: Contribution to conference › Poster › Research › peer-review

    55. Published

      The palmitoylated α-peptide/β-peptoid hybrid Pam-(Lys-βNSpe)6-NH2 is a novel host defense peptidomimetic with potent anti-inflammatory activity

      Skovbakke, S. L., Heegaard, P. M. H., Forsman, H., Dahlgren, C. & Franzyk, Henrik, 2014.

      Research output: Contribution to conference › Poster › Research

    56. Published

      The supramolecular structure is decisive for the immunoactivity of a mycobacterial lipid in vitro.

      Martin-Bertelsen, Birte, Korsholm, K. S., Christensen, D., Franzyk, Henrik, Yaghmur, Anan & Foged, Camilla, 2014. 1 p.

      Research output: Contribution to conference › Poster › Research

    57. 2013
    58. Published

      Characterization of a proteolytically stable multifunctional host defense peptidomimetic

      Jahnsen, R. D., Haney, E. F., Franzyk, Henrik & Hancock, R. E. W., 10 Oct 2013, In: Chemistry & Biology. 20, 10, p. 1286-1295 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    59. Published

      Selectivity in the potentiation of antibacterial activity of α-peptide/β-peptoid peptidomimetics and antimicrobial peptides by human blood plasma

      Hein-Kristensen, L., Knapp, K. M., Franzyk, Henrik & Gram, L., 27 Aug 2013, In: Research in Microbiology. 164, 9, p. 933-940 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    60. Published

      Adaptive Evolution of Escherichia coli to an α-Peptide/β-Peptoid Peptidomimetic Induces Stable Resistance

      Hein-Kristensen, L., Franzyk, Henrik, Holch, A. & Gram, L., 2013, In: PLOS ONE. 8, 9, p. e73620

      Research output: Contribution to journal › Journal article › Research › peer-review

    61. Published

      Antimicrobial Peptidomimetics

      Jahnsen, R. O., Frimodt-Møller, N. & Franzyk, Henrik, 2013.

      Research output: Contribution to conference › Poster › Research

    62. Published

      Antimicrobial and cell-penetrating properties of penetratin analogs: effect of sequence and secondary structure

      Bahnsen, J. S., Franzyk, Henrik, Sandberg-Schaal, A. & Nielsen, Hanne Mørck, 2013, In: B B A - Biomembranes. 1828, 2, p. 223-232 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    63. Published

      Cell-penetrating Peptides Targeting Intracellular Infections

      Bahnsen, J. S., Franzyk, Henrik, Sandberg-Schaal, A. & Nielsen, Hanne Mørck, 2013.

      Research output: Contribution to conference › Poster › Research › peer-review

    64. Published

      High in vitro antimicrobial activity of ß-peptoid-peptide hybrid oligomers against planktonic and biofilm cultures of Staphylococcus epidermidis

      Liu, Y., Knapp, K. M., Yang, L., Molin, S., Franzyk, Henrik & Folkesson, A., 2013, In: International Journal of Antimicrobial Agents. 41, 1, p. 20-27 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    65. Published

      Loading of an antimicrobial peptide into PLGA nanoparticles increases its efficacy against intracellular Staphylococcus aureus infection in the Calu-3 bronchial epithelial cell line

      Water, J. J., Foged, Camilla, Franzyk, Henrik & Nielsen, Hanne Mørck, 2013.

      Research output: Contribution to conference › Poster › Research › peer-review

    66. Published

      Novel Silicone Composite for Prolonged Release of Antimicrobial Peptides

      Steffensen, S. L., Møller, E. H., Franzyk, Henrik, Jensen, M. G., Alm, M. & Nielsen, Hanne Mørck, 2013.

      Research output: Contribution to conference › Poster › Research › peer-review

    67. Published

      The supramolecular structure is decisive for the immunostimulatory properties of synthetic analogues of a mycobacterial lipid in vitro

      Martin-Bertelsen, Birte, Korsholm, K. S., Rose, F., Nordly, P. J., Franzyk, Henrik, Andersen, P., Agger, E. M., Christensen, D., Yaghmur, Anan & Foged, Camilla, 2013, In: R S C Advances. 3, 43, p. 20673-20683

      Research output: Contribution to journal › Journal article › Research › peer-review

    68. 2012
    69. Published

      Antimicrobial activity of peptidomimetics against multidrug-resistant Escherichia coli: a comparative study of different backbones

      Jahnsen, R. D., Frimodt-Møller, N. & Franzyk, Henrik, 2012, In: Journal of Medicinal Chemistry. 55, 16, p. 7253-61 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    70. Published

      Antimicrobial peptides as novel delivery vehicles for genetic antibiotics

      Seigan, G. B., Franzyk, Henrik & Nielsen, Peter E., 2012, In: Journal of Peptide Science. 18, Suppl. 1, p. S116-S117

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    71. Published

      Antimicrobial peptides as novel delivery vehicles for genetic antibiotics

      Seigan, G. B., Franzyk, Henrik & Nielsen, Peter E., 2012. 2 p.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    72. Published

      Antimikrobielle peptider: et nyt våben mod multiresistente bakterier

      Munk, J., Hansen, Paul Robert & Franzyk, Henrik, 2012, In: Lægemiddelforskning. 2012, p. 9-11

      Research output: Contribution to journal › Journal article › Communication

    73. Published

      Escherichia coli with resistance to α-peptide/β-peptoid peptidomimetics: Mutation of a gene related to structural changes of cell wall peptidoglycan

      Hein-Kristensen, L., Franzyk, Henrik & Gram, L., 2012.

      Research output: Contribution to conference › Poster › Research

    74. Published

      Håb om at ramme latente bakterier i deres skjul

      Bahnsen, J. S., Water, J. J., Foged, Camilla, Franzyk, Henrik & Nielsen, Hanne Mørck, 2012, In: Lægemiddelforskning 2012. 2012, p. 12-14

      Research output: Contribution to journal › Journal article › Research

    75. Published

      Induction of antimicrobial activity against ESBL and NDM-1 producing Escherichia coli by peptide backbone modifications - a comparative study

      Jahnsen, R. O., Frimodt-Møller, N. & Franzyk, Henrik, 2012.

      Research output: Contribution to conference › Poster › Research

    76. Published

      Interaction of peptidomimetics with bilayer membranes: biophysical characterization and cellular uptake

      Jing, X., Kasimova, M. R., Simonsen, A. H., Jørgensen, Lene, Malmsten, M., Franzyk, Henrik & Foged, Camilla, 2012, In: Langmuir. 28, 11, p. 5167-5175

      Research output: Contribution to journal › Journal article › Research › peer-review

    77. Published

      Membrane adsorption and binding, cellular uptake and cytotoxicity of cell-penetrating peptidomimetics with α-peptide/β-peptoid backbone: effects of hydrogen bonding and α-chirality in the β-peptoid residues

      Jing, X., Yang, M., Kasimova, M. R., Malmsten, M., Franzyk, Henrik, Jørgensen, Lene, Foged, Camilla & Nielsen, Hanne Mørck, 2012, In: BBA General Subjects. 1818, 11, p. 2660-2668 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    78. Published

      Solid-phase route to Fmoc-protected cationic amino acid building blocks

      Clausen, J. D., Linderoth, L., Nielsen, Hanne Mørck & Franzyk, Henrik, 2012, In: Amino Acids. 43, 4, p. 1633-41 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    79. Published

      The antimicrobial and cell-penetrating effects of the CPP penetratin and derived analogues.

      Bahnsen, J. S., Franzyk, Henrik & Nielsen, Hanne Mørck, 2012.

      Research output: Contribution to conference › Poster › Research

    80. 2011
    81. Published

      Bacterial membrane activity of alpha-peptide/beta-peptoid chimeras: influence of amino acid composition and chain length on the activity against different bacterial strains

      Hein-Kristensen, L., Knapp, K. M., Franzyk, Henrik & Gram, L., 22 Jun 2011, In: B M C Microbiology. 11, 1, p. 144

      Research output: Contribution to journal › Journal article › Research › peer-review

    82. Published

      Incorporation of a synthetic mycobacterial monomycoloyl glycerol analogue stabilizes dimethyldioctadecylammonium liposomes and potentiates their adjuvant effect in vivo

      Nordly, P. J., Korsholm, K. S., Pedersen, E. A., Khilji, T. S., Franzyk, Henrik, Jørgensen, Lene, Nielsen, Hanne Mørck, Agger, E. M. & Foged, Camilla, 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 77, 1, p. 89-98

      Research output: Contribution to journal › Journal article › Research › peer-review

    83. 2010
    84. Published

      Erratum: Aminolysis of resin-bound N-nosylaziridine-2-carboxylic acids (Organic Letters (2006) 8 (3371))

      Olsen, Christian Adam, Christensen, C., Nielsen, Birgitte, Farah, M. M., Witt, M., Clausen, Rasmus Prætorius, Kristensen, Jesper Langgaard, Franzyk, Henrik & Jaroszewski, J. W., 15 Oct 2010, In: Organic Letters. 12, 20, p. 4708 1 p.

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    85. Published

      Antimicrobial, hemolytic, and cytotoxic activities of β-peptoid- peptide hybrid oligomers: Improved properties compared to natural AMPs (ChemBioChem (2010) 11, (152-160))

      Olsen, Christian Adam, Ziegler, H. L., Nielsen, Hanne Mørck, Frimodt-Møller, N., Jaroszewski, J. W. & Franzyk, Henrik, 16 Aug 2010, In: ChemBioChem. 11, 12, 1 p.

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    86. Published

      A synthetic mycobacterial monomycoloyl glycerol analogue stabilizes DDA liposomes

      Nordly, P. J., Pedersen, E. A., Khiljii, T. S., Agger, E. M., Jørgensen, Lene, Nielsen, Hanne Mørck, Korsholm, K. S., Franzyk, Henrik & Foged, Camilla, 2010, In: CRS Newsletter. 27, 2, p. 12 14 p.

      Research output: Contribution to journal › Journal article › Research

    87. Published

      Antimicrobial, hemolytic, and cytotoxic activities of ß-peptoid-peptide hybrid oligomers: Improved properties compared to natural AMPs

      Olsen, Christian Adam, Ziegler, H. L., Nielsen, Hanne Mørck, Frimodt-Møller, N., Jaroszewski, J. W. & Franzyk, Henrik, 2010, In: ChemBioChem. 11, 10, p. 1356-1360

      Research output: Contribution to journal › Journal article › Research › peer-review

    88. Published

      Assessment of structurally diverse philanthotoxin analogues for inhibitory activity on ionotropic glutamate receptor subtypes: Discovery of nanomolar, nonselective, and use-dependent antagonists

      Frølund, S., Bella, A., Kristensen, Anders Skov, Ziegler, H. L., Witt, M., Olsen, C. A., Strømgaard, Kristian, Franzyk, Henrik & Jaroszewski, J. W., 2010, In: Journal of Medicinal Chemistry. 53, 20, p. 7441-7451

      Research output: Contribution to journal › Journal article › Research › peer-review

    89. Published

      Comparison of synthesis and antibacterial activity of a- and ß-peptoids

      Knapp, K. M., Franzyk, Henrik & Jahnsen, R., 2010. 1 p.

      Research output: Contribution to conference › Poster › Research › peer-review

    90. Published

      Linking activity and mode of action to length in a novel peptidomimetics library

      Hein-Kristensen, L., Franzyk, Henrik & Gram, L., 2010.

      Research output: Contribution to conference › Poster › Research

    91. Published

      Microcalorimetric and spectroscopic studies on the mechanism of interaction between novel peptidomimetics and lipid bilayers

      Nielsen, Hanne Mørck, Jing, X., Simonsen, A., Kasimova, M. R., Malmsten, M., Franzyk, Henrik & Foged, Camilla, 2010, In: Journal of Peptide Science. 16, s1, p. 151 1 p.

      Research output: Contribution to journal › Conference abstract in journal › Research

    92. Published

      Microcalorimetric and spectroscopic studies on the mechanism of interaction between novel peptoids and lipid bilayers - effect of length, charge and N-terminal end group

      Jing, X., Simonsen, A. H., Kasimova, M. R., Franzyk, Henrik, Foged, Camilla & Nielsen, Hanne Mørck, 2010, In: Drug Discovery Today. 15, 23/24, p. 1109

      Research output: Contribution to journal › Conference abstract in journal › Research

    93. Published

      Ring opening of a Resin-bound chiral aziridine with phenols

      Ottesen, L. K., Jaroszewski, J. W. & Franzyk, Henrik, 2010, In: Synfacts. 2010, 11, p. 1319 1 p.

      Research output: Contribution to journal › Journal article › Research

    94. Published

      Ring opening of a resin-bound chiral aziridine with phenol nucleophiles

      Ottesen, L. K., Jaroszewski, J. W. & Franzyk, Henrik, 2010, In: Journal of Organic Chemistry. 75, 15, p. 4983-4991

      Research output: Contribution to journal › Journal article › Research › peer-review

    95. Published

      Studies towards improved cell-penetrating peptide-promoted macromolecular drug delivery

      Dahlqvist Clausen, J. A., Linderoth, L., Andersen, R. B., Franzyk, Henrik & Nielsen, Hanne Mørck, 2010, In: Drug Discovery Today. 15, 23-24, p. 1109 1 p., A81.

      Research output: Contribution to journal › Conference abstract in journal › Research

    96. Published

      Studies towards improved stability and permeability of a cell-penetrating peptide

      Dahlqvist Clausen, J. A., Linderoth, L., Andersen, R. B., Franzyk, Henrik & Nielsen, Hanne Mørck, 2010, In: Journal of Peptide Science. 16, p. 148 1 p.

      Research output: Contribution to journal › Conference abstract in journal › Research

    97. 2009
    98. Published

      Expedite Protocol for Construction of Chiral Regioselectively N-Protected Monosubstituted Piperazine, 1,4-Diazepane, and 1,4-Diazocane Building Blocks

      Crestey, F., Witt, M., Jaroszewski, J. W. & Franzyk, Henrik, 11 Jun 2009, In: Journal of Organic Chemistry. 74, 15, p. 5652-5655

      Research output: Contribution to journal › Journal article › Research › peer-review

    99. Published

      Selectively N-protected enantiopure 2,5-disubstituted piperazines: Avoiding the pitfalls in solid-phase Fukuyama-Mitsunobu cyclizations

      Ottesen, L. K., Olsen, Christian Adam, Witt, M., Jaroszewski, J. W. & Franzyk, Henrik, 2009, In: Chemistry: A European Journal. 15, 12, p. 2966-2978

      Research output: Contribution to journal › Journal article › Research › peer-review

    100. 2008
    101. Published

      Cellular uptake and membrane-destabilising properties of a-peptide/ß-peptoid chimeras: lessons for the design of new cell-penetrating peptides

      Foged, Camilla, Franzyk, Henrik, Bahrami, S., Frøkjær, Sven, Jaroszewski, J. W., Nielsen, Hanne Mørck & Olsen, Christian Adam, 2008, In: BBA General Subjects. 1778, 11, p. 2487-2495

      Research output: Contribution to journal › Journal article › Research › peer-review

    102. Published

      Dimeric Building Blocks for Solid-Phase Synthesis of α-Peptide-β-Peptoid Chimeras

      Seigan, G. B., Vedel, L., Matthias, W., Jaroszewski, J. W., Olsen, Christian Adam & Franzyk, Henrik, 2008, In: Synthesis. 2008, 15, p. 2381-2390 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    103. Published

      Efficient loading of primary alcohols onto a solid phase using a trityl bromide linker

      Crestey, F., Ottesen, L. K., Jaroszewski, J. W. & Franzyk, Henrik, 2008, In: Tetrahedron Letters. 49, 41, p. 5890-5893

      Research output: Contribution to journal › Journal article › Research › peer-review

    104. Published

      Electrophysiological characterization of analogues of philanthotoxin-343 on ionotropic glutamate receptors

      Frølund, S. U., Ziegler, H. L., Franzyk, Henrik, Strømgaard, Kristian, Kristensen, Anders Skov & Jaroszewski, J. W., 2008.

      Research output: Contribution to conference › Poster › Research

    105. Published

      Lægemidler fra naturstoffer: fortid eller fremtid?

      Jaroszewski, J. W., Christensen, Søren Brøgger, Franzyk, Henrik, Stærk, Dan & Ziegler, H., 2008, In: Lægemiddelforskning. p. 4-6

      Research output: Contribution to journal › Journal article › Communication

    106. Published

      Microwave-Assisted Ring-Opening of Activated Aziridines with Resin-Bound Amines

      Franzyk, Henrik, Crestey, F., Witt, M., Frydenvang, Karla Andrea, Stærk, Dan & Jaroszewski, J., 2008, In: Synfacts. 7, p. 769

      Research output: Contribution to journal › Journal article › Research › peer-review

    107. Published

      Microwave-assisted ring-opening of activated aziridines with resin-bound amines

      Crestey, F., Witt, M., Frydenvang, Karla Andrea, Stærk, Dan, Jaroszewski, J. W. & Franzyk, Henrik, 2008, In: Journal of Organic Chemistry. 73, 9, p. 3566-3569 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    108. Published

      Solid-phase peptide synthesis and circular dichroism study of chiral ß-peptoid homooligomers

      Olsen, Christian Adam, Lambert, M., Witt, M., Franzyk, Henrik & Jaroszewski, J. W., 2008, In: Amino Acids. 34, 3, p. 465-471

      Research output: Contribution to journal › Journal article › Research › peer-review

    109. 2007
    110. Published

      Antiplasmodial and prehemolytic activities of alpha-peptide-beta-peptoid chimeras

      Vedel, L., Bonke, G., Foged, Camilla, Ziegler, H. L., Franzyk, Henrik, Jaroszewski, J. W. & Olsen, Christian Adam, 2007, In: ChemBioChem. 8, 15, p. 1781-1784 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    111. Published

      Aziridines in parallel- and solid-phase synthesis

      Olsen, Christian Adam, Bonke, G., Vedel, L., Franzyk, Henrik & Jaroszewski, J. W., 2007, In: European Journal of Organic Chemistry. 2007, 11, p. 1717-1724

      Research output: Contribution to journal › Review › Research › peer-review

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