Henrik Franzyk

Henrik Franzyk

Associate Professor

Member of:

    ORCID: 0000-0002-2822-1927

    Publication year:
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    51 - 100 out of 274Page size: 50
    1. 2004
    2. Published

      Cyclopentanoid cyanohydrin glucosides from Passiflora mixta

      Bylov, T., Franzyk, Henrik & Jaroszewski, J. W., 2004, In: Biochemical Systematics and Ecology. 32, p. 695-698 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Diols as Building Blocks in Solid-Phase Synthesis of Polyamine Toxins by Fukuyama-Mitsunobu Alkylation

      Olsen, Christian Adam, Witt, M., Jaroszewski, J. W. & Franzyk, Henrik, 2004, In: Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. p. 473-476 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Dopaol 2-keto- and 2,3-diketoglycosides from Chelone obliqua

      Franzyk, Henrik, Olsen, C. E. & Jensen, Søren, 2004, In: Journal of Natural Products. 67, 6, p. 1052-4 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Erythrocyte membrane modifying agents and the inhibition of Plasmodium falciparum growth: structure-activity relationships for betulinic acid analogues

      Ziegler, H. L., Franzyk, Henrik, Sairafianpour, M., Tabatabai, M., Tehrani, M. D., Bagherzadeh, K., Hägerstrand, H., Stærk, Dan & Jaroszewski, J. W., 2004, In: Bioorganic & Medicinal Chemistry. 12, p. 119-127

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Expedient protocol for solid-phase synthesis of secondary and tertiary amines

      Olsen, Christian Adam, Witt, M., Jaroszewski, J. W. & Franzyk, Henrik, 2004, In: Organic Letters. 6, 12, p. 1935-8 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Solid-phase synthesis of rigid acylpolyamines using temporary N-4,4'-dimethoxytrityl protection in the presence of trityl linkers

      Olsen, Christian Adam, Witt, M., Jaroszewski, J. W. & Franzyk, Henrik, 2004, In: Journal of Organic Chemistry. 69, 18, p. 6149-52 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. 2005
    9. Published

      Naravelia zeyanica: occurrence of primary benzamides in flowering plants

      Jaroszewski, J. W., Stærk, Dan, Holm-Møller, S. B., Jensen, T. H. & Franzyk, Henrik, 2005, In: Natural Product Research. 19, 3, p. 291-294

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Fukuyama-Mitsunobu Alkylation in Amine Synthesis on Solid Phase Revisited: N-Alkylation with Secondary Alcohols and Synthesis of Curtatoxins

      Olsen, Christian Adam, Witt, M., Hansen, S. H., Jaroszewski, J. W. & Franzyk, Henrik, 2005, In: Tetrahedron. 61, p. 6046-6055 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      N-Alkylation Reactions and Indirect Formation of Amino Functionalities in Solid-Phase Synthesis

      Olsen, Christian Adam, Jaroszewski, J. W. & Franzyk, Henrik, 2005, In: Synthesis. p. 2631-2653 23 p.

      Research output: Contribution to journal › Review › Research › peer-review

    12. Published

      New Linker Strategies in SPS of Neuroactive Wasp Toxin Analogues

      Olsen, Christian Adam, Jaroszewski, J. W. & Franzyk, Henrik, 2005.

      Research output: Contribution to conference › Poster › Research

    13. Published

      On-Resin Carboxy Group Activation of ω-Amino Acids in Solid-Phase Synthesis­ of Philanthotoxin Analogues

      Franzyk, Henrik, Jørgensen, M. R., Jaroszewski, J. W. & Witt, M., 2005, In: Synthesis.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      On-resin Carboxy Group Activation of ω-Amino Acids in Solid-Phase Synthesis of Philanthotoxin Analogues

      Jørgensen, M. R., Jaroszewski, J. W., Witt, M. & Franzyk, Henrik, 2005, In: Synthesis. p. 2687-2694 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Side-chain-anchored N(alpha)-Fmoc-Tyr-OPfp for bidirectional solid-phase synthesis

      Olsen, Christian Adam, Jørgensen, M., Hansen, S. H., Witt, M., Jaroszewski, J. W. & Franzyk, Henrik, 2005, In: Organic Letters. 7, 9, p. 1703-6 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      The effects of conformational constraints and steric bulk in the amino acid moiety of philanthotoxins on AMPAR antagonism

      Jørgensen, M., Olsen, Christian Adam, Mellor, I. R., Usherwood, P. N. R., Witt, M., Franzyk, Henrik & Jaroszewski, J. W., 2005, In: Journal of Medicinal Chemistry. 48, 1, p. 56-70 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Erratum: "Naravelia zeylanica: Occurrence of primary benzamides in flowering plants" (Natural Product Research vol. 19 (3) (291-294))

      Jaroszewski, J. W., Stærk, Dan, Holm-Møller, S. B., Jensen, T. H., Franzyk, Henrik & Somanadhan, B., 1 Jun 2005, In: Natural Product Research. 19, 4, 1 p.

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    18. 2006
    19. Published

      Aminolysis of resin-bound N-nosylaziridine-2-carboxylic acids

      Olsen, Christian Adam, Christensen, C., Nielsen, Birgitte, Farah, M. M., Mohamed, F. M., Witt, M., Clausen, Rasmus Prætorius, Kristensen, Jesper Langgaard, Franzyk, Henrik & Jaroszewski, J. W., 2006, In: Organic Letters. 8, 15, p. 3371-4 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Kunstige forsvarspeptider

      Olsen, Christian Adam, Franzyk, Henrik & Jaroszewski, J. W., 2006, In: Lægemiddelforskning. p. 18-19 2 p.

      Research output: Contribution to journal › Journal article › Communication

    21. Published

      Nanomolær inhibering med hvepsetoksinanaloger – syntese og elektrofysiologi

      Olsen, Christian Adam, Franzyk, Henrik & Jaroszewski, J. W., 2006, In: Dansk Kemi. 87, p. 23-26 4 p.

      Research output: Contribution to journal › Journal article › Communication

    22. Published

      Protolytic properties of polyamine wasp toxin analogues studied by 13C NMR spectroscopy

      Strømgaard, Kristian, Piazzi, L., Olsen, Christian Adam, Franzyk, Henrik & Jaroszewski, J. W., 2006, In: Magnetic Resonance in Chemistry. 44, 11, p. 1013-22 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Tuning wasp toxin structure for nicotinic receptor antagonism: cyclohexylalanine-containing analogues as potent and voltage-dependent blockers

      Olsen, Christian Adam, Mellor, I. R., Wellendorph, Petrine, Usherwood, P. N. R., Witt, M., Franzyk, Henrik & Jaroszewski, J. W., 2006, In: ChemMedChem. 1, 3, p. 303-5 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. 2007
    25. Published

      Antiplasmodial and prehemolytic activities of alpha-peptide-beta-peptoid chimeras

      Vedel, L., Bonke, G., Foged, Camilla, Ziegler, H. L., Franzyk, Henrik, Jaroszewski, J. W. & Olsen, Christian Adam, 2007, In: ChemBioChem. 8, 15, p. 1781-1784 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Aziridines in parallel- and solid-phase synthesis

      Olsen, Christian Adam, Bonke, G., Vedel, L., Franzyk, Henrik & Jaroszewski, J. W., 2007, In: European Journal of Organic Chemistry. 2007, 11, p. 1717-1724

      Research output: Contribution to journal › Review › Research › peer-review

    27. Published

      Noter til bioorganisk kemi M23-1

      Franzyk, Henrik, Christensen, Søren Brøgger & Jaroszewski, J. W., 2007, København: Københavns Universitet, Det Farmaceutiske Fakultet, Institut for Medicinalkemi.

      Research output: Book/Report › Compendium/lecture notes › Education

    28. Published

      Solid-phase synthesis of neuroactive spider-wasp hybrid toxin analogues using a backbone amide linker

      Olsen, Christian Adam, Witt, M., Franzyk, Henrik & Jaroszewski, J. W., 2007, In: Tetrahedron Letters. 48, 3, p. 405-408

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Øvelsesvejledning til bioorganisk kemi: øvelser M23-2

      Franzyk, Henrik, 2007, Københavns Universitet, Det Farmaceutiske Fakultet, Institut for Medicinalkemi.

      Research output: Book/Report › Compendium/lecture notes › Education

    30. Published

      α-Peptide/ß-Peptoid Chimeras

      Olsen, Christian Adam, Bonke, G., Vedel, L., Adsersen, A., Witt, M., Franzyk, Henrik & Jaroszewski, J. W., 2007, In: Organic Letters. 9, 8, p. 1549–1552 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. 2008
    32. Published

      Cellular uptake and membrane-destabilising properties of a-peptide/ß-peptoid chimeras: lessons for the design of new cell-penetrating peptides

      Foged, Camilla, Franzyk, Henrik, Bahrami, S., Frøkjær, Sven, Jaroszewski, J. W., Nielsen, Hanne Mørck & Olsen, Christian Adam, 2008, In: BBA General Subjects. 1778, 11, p. 2487-2495

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Dimeric Building Blocks for Solid-Phase Synthesis of α-Peptide-β-Peptoid Chimeras

      Seigan, G. B., Vedel, L., Matthias, W., Jaroszewski, J. W., Olsen, Christian Adam & Franzyk, Henrik, 2008, In: Synthesis. 2008, 15, p. 2381-2390 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      Efficient loading of primary alcohols onto a solid phase using a trityl bromide linker

      Crestey, F., Ottesen, L. K., Jaroszewski, J. W. & Franzyk, Henrik, 2008, In: Tetrahedron Letters. 49, 41, p. 5890-5893

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Electrophysiological characterization of analogues of philanthotoxin-343 on ionotropic glutamate receptors

      Frølund, S. U., Ziegler, H. L., Franzyk, Henrik, Strømgaard, Kristian, Kristensen, Anders Skov & Jaroszewski, J. W., 2008.

      Research output: Contribution to conference › Poster › Research

    36. Published

      Lægemidler fra naturstoffer: fortid eller fremtid?

      Jaroszewski, J. W., Christensen, Søren Brøgger, Franzyk, Henrik, Stærk, Dan & Ziegler, H., 2008, In: Lægemiddelforskning. p. 4-6

      Research output: Contribution to journal › Journal article › Communication

    37. Published

      Microwave-Assisted Ring-Opening of Activated Aziridines with Resin-Bound Amines

      Franzyk, Henrik, Crestey, F., Witt, M., Frydenvang, Karla Andrea, Stærk, Dan & Jaroszewski, J., 2008, In: Synfacts. 7, p. 769

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Microwave-assisted ring-opening of activated aziridines with resin-bound amines

      Crestey, F., Witt, M., Frydenvang, Karla Andrea, Stærk, Dan, Jaroszewski, J. W. & Franzyk, Henrik, 2008, In: Journal of Organic Chemistry. 73, 9, p. 3566-3569 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Solid-phase peptide synthesis and circular dichroism study of chiral ß-peptoid homooligomers

      Olsen, Christian Adam, Lambert, M., Witt, M., Franzyk, Henrik & Jaroszewski, J. W., 2008, In: Amino Acids. 34, 3, p. 465-471

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. 2009
    41. Published

      Selectively N-protected enantiopure 2,5-disubstituted piperazines: Avoiding the pitfalls in solid-phase Fukuyama-Mitsunobu cyclizations

      Ottesen, L. K., Olsen, Christian Adam, Witt, M., Jaroszewski, J. W. & Franzyk, Henrik, 2009, In: Chemistry: A European Journal. 15, 12, p. 2966-2978

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Expedite Protocol for Construction of Chiral Regioselectively N-Protected Monosubstituted Piperazine, 1,4-Diazepane, and 1,4-Diazocane Building Blocks

      Crestey, F., Witt, M., Jaroszewski, J. W. & Franzyk, Henrik, 11 Jun 2009, In: Journal of Organic Chemistry. 74, 15, p. 5652-5655

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. 2010
    44. Published

      A synthetic mycobacterial monomycoloyl glycerol analogue stabilizes DDA liposomes

      Nordly, P. J., Pedersen, E. A., Khiljii, T. S., Agger, E. M., Jørgensen, Lene, Nielsen, Hanne Mørck, Korsholm, K. S., Franzyk, Henrik & Foged, Camilla, 2010, In: CRS Newsletter. 27, 2, p. 12 14 p.

      Research output: Contribution to journal › Journal article › Research

    45. Published

      Antimicrobial, hemolytic, and cytotoxic activities of ß-peptoid-peptide hybrid oligomers: Improved properties compared to natural AMPs

      Olsen, Christian Adam, Ziegler, H. L., Nielsen, Hanne Mørck, Frimodt-Møller, N., Jaroszewski, J. W. & Franzyk, Henrik, 2010, In: ChemBioChem. 11, 10, p. 1356-1360

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Assessment of structurally diverse philanthotoxin analogues for inhibitory activity on ionotropic glutamate receptor subtypes: Discovery of nanomolar, nonselective, and use-dependent antagonists

      Frølund, S., Bella, A., Kristensen, Anders Skov, Ziegler, H. L., Witt, M., Olsen, C. A., Strømgaard, Kristian, Franzyk, Henrik & Jaroszewski, J. W., 2010, In: Journal of Medicinal Chemistry. 53, 20, p. 7441-7451

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Comparison of synthesis and antibacterial activity of a- and ß-peptoids

      Knapp, K. M., Franzyk, Henrik & Jahnsen, R., 2010. 1 p.

      Research output: Contribution to conference › Poster › Research › peer-review

    48. Published

      Linking activity and mode of action to length in a novel peptidomimetics library

      Hein-Kristensen, L., Franzyk, Henrik & Gram, L., 2010.

      Research output: Contribution to conference › Poster › Research

    49. Published

      Microcalorimetric and spectroscopic studies on the mechanism of interaction between novel peptidomimetics and lipid bilayers

      Nielsen, Hanne Mørck, Jing, X., Simonsen, A., Kasimova, M. R., Malmsten, M., Franzyk, Henrik & Foged, Camilla, 2010, In: Journal of Peptide Science. 16, s1, p. 151 1 p.

      Research output: Contribution to journal › Conference abstract in journal › Research

    50. Published

      Microcalorimetric and spectroscopic studies on the mechanism of interaction between novel peptoids and lipid bilayers - effect of length, charge and N-terminal end group

      Jing, X., Simonsen, A. H., Kasimova, M. R., Franzyk, Henrik, Foged, Camilla & Nielsen, Hanne Mørck, 2010, In: Drug Discovery Today. 15, 23/24, p. 1109

      Research output: Contribution to journal › Conference abstract in journal › Research

    51. Published

      Ring opening of a Resin-bound chiral aziridine with phenols

      Ottesen, L. K., Jaroszewski, J. W. & Franzyk, Henrik, 2010, In: Synfacts. 2010, 11, p. 1319 1 p.

      Research output: Contribution to journal › Journal article › Research

    52. Published

      Ring opening of a resin-bound chiral aziridine with phenol nucleophiles

      Ottesen, L. K., Jaroszewski, J. W. & Franzyk, Henrik, 2010, In: Journal of Organic Chemistry. 75, 15, p. 4983-4991

      Research output: Contribution to journal › Journal article › Research › peer-review

    53. Published

      Studies towards improved cell-penetrating peptide-promoted macromolecular drug delivery

      Dahlqvist Clausen, J. A., Linderoth, L., Andersen, R. B., Franzyk, Henrik & Nielsen, Hanne Mørck, 2010, In: Drug Discovery Today. 15, 23-24, p. 1109 1 p., A81.

      Research output: Contribution to journal › Conference abstract in journal › Research

    54. Published

      Studies towards improved stability and permeability of a cell-penetrating peptide

      Dahlqvist Clausen, J. A., Linderoth, L., Andersen, R. B., Franzyk, Henrik & Nielsen, Hanne Mørck, 2010, In: Journal of Peptide Science. 16, p. 148 1 p.

      Research output: Contribution to journal › Conference abstract in journal › Research

    55. Published

      Antimicrobial, hemolytic, and cytotoxic activities of β-peptoid- peptide hybrid oligomers: Improved properties compared to natural AMPs (ChemBioChem (2010) 11, (152-160))

      Olsen, Christian Adam, Ziegler, H. L., Nielsen, Hanne Mørck, Frimodt-Møller, N., Jaroszewski, J. W. & Franzyk, Henrik, 16 Aug 2010, In: ChemBioChem. 11, 12, 1 p.

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    56. Published

      Erratum: Aminolysis of resin-bound N-nosylaziridine-2-carboxylic acids (Organic Letters (2006) 8 (3371))

      Olsen, Christian Adam, Christensen, C., Nielsen, Birgitte, Farah, M. M., Witt, M., Clausen, Rasmus Prætorius, Kristensen, Jesper Langgaard, Franzyk, Henrik & Jaroszewski, J. W., 15 Oct 2010, In: Organic Letters. 12, 20, p. 4708 1 p.

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    57. 2011
    58. Published

      Incorporation of a synthetic mycobacterial monomycoloyl glycerol analogue stabilizes dimethyldioctadecylammonium liposomes and potentiates their adjuvant effect in vivo

      Nordly, P. J., Korsholm, K. S., Pedersen, E. A., Khilji, T. S., Franzyk, Henrik, Jørgensen, Lene, Nielsen, Hanne Mørck, Agger, E. M. & Foged, Camilla, 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 77, 1, p. 89-98

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 1302063