Jan Stenvang

Jan Stenvang

Associate Professor


  1. Published

    The invariant chain CD74 protein is a cell surface binding partner of TIMP-1 in breast cancer cells

    Høeberg, M., Noer, Julie Boertmann, Vistesen, M. V., Bartels, Annette Snejbjerg, Bech, E. M., Nygård, S. B., Lademann, U., Stenvang, Jan, Liu, S., Fuglsang, Anja Thoe, Brünner, N. & Moreira, José, 2023, In: Molecular Oncology. 17, 8, p. 1595-1612

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Characterization of resistance to a recombinant hexameric Fas-ligand (APO010) in human cancer cell lines

    Jandu, H., Nielsen, A., Brunner, N., Hansen, A., Knudsen, S., Stenvang, Jan & Jensen, P. B., 2020, In: Experimental Hematology. 87, p. 33-41

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Molecular characterization of irinotecan (SN-38) resistant human breast cancer cell lines

    Jandu, H., Aluzaité, K., Fogh, L., Thrane, S. W., Noer, J. B., Proszek, J., Nguyen Do, K., Hansen, S. N., Damsgaard-Hansen, B., Nielsen, S. L., Stougaard, M., Knudsen, B. R., Moreira, J., Hamerlik, P., Gajjar, M., Smid, M., Martens, J., Foekens, J., Pommier, Y., Brünner, N. & 2 others, Rasmussen, A. S. & Stenvang, Jan, 22 Jan 2016, In: B M C Cancer. 16, 13 p., 34.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Purification and characterization of bioactive his6-tagged recombinant human tissue inhibitor of metalloproteinases-1 (TIMP-1) protein expressed at high yields in mammalian cells

    Jensen, L. V., Lademann, U. A., Andersen, E. V., Højrup, P., Thaysen-Andersen, M., Krogh, B. O., Viuff, B. M., Brünner, N., Stenvang, Jan & Moreira, José, 2014, In: Protein Expression and Purification. 101, p. 157-164 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Submitted

    MicroRNA profiling in generated oxaliplatin- and SN-38-resistant colorectal cancer cell lines

    Jensen, N. F., Søkilde, R., Stenvang, Jan, Litman, T., Brunner, N. & Rømer, M. U. K., 2011, (Submitted). 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  6. Published

    Characterization of DNA topoisomerase I in three SN-38 resistant human colon cancer cell lines reveals a new pair of resistance-associated mutations

    Jensen, N. F., Agama, K., Roy, A., Smith, D. H., Pfister, T. D., Rømer, M. U., Zhang, H., Doroshow, J. H., Knudsen, B. R., Stenvang, Jan, Brünner, N. & Pommier, Y., 2016, In: Journal of Experimental and Clinical Cancer Research (Online). 35, 14 p., 56.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Establishment and characterization of models of chemotherapy resistance in colorectal cancer: towards a predictive signature of chemoresistance

    Jensen, N. F., Stenvang, J., Beck, M. K., Hanáková, B., Belling, K. C., Do, K. N., Viuff, B. M., Nygård, S. B., Gupta, R., Rasmussen, M. H., Tarpgaard, L. S., Hansen, T. P., Budinská, E., Pfeiffer, P., Bosman, F., Tejpar, S., Roth, A., Delorenzi, M., Andersen, C. L., Rømer, M. U. K. & 2 others, Brünner, N. & Moreira, José, 24 Feb 2015, In: Molecular Oncology. 9, 6, p. 1169-1185 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Integrative analysis of miRNA and gene expression reveals regulatory networks in tamoxifen-resistant breast cancer

    Joshi, T., Elias, D., Stenvang, Jan, Alves, C. M. L., Teng, F., Lyng, M. B., Lykkesfeldt, A. E., Brünner, N., Wang, J., Gupta, R., Workman, C. T. & Ditzel, H. J., 2016, In: OncoTarget. 7, 35, p. 57239-57253 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Insulin-like growth factor binding protein 2 is a marker for antiestrogen resistant human breast cancer cell lines but is not a major growth regulator

    Juncker-Jensen, A., Lykkesfeldt, A. E., Worm, J., Ralfkiær, U., Espelund, U. & Stenvang, Jan, 1 Aug 2006, In: Growth Hormone and IGF Research. 16, 4, p. 224-239 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Synthesis of thiazole linked chalcones and their pyrimidine analogues as anticancer agents

    Kesari, C., Rama, K. R., Sedighi, K., Stenvang, Jan, Björkling, Fredrik, Kankala, S. & Thota, N., 2021, In: Synthetic Communications. 51, 9, p. 1406-1416 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Conserved residues and their role in the structure, function, and stability of acyl-coenzyme A binding protein

    Kragelund, B. B., Poulsen, K., Andersen, K. V., Baldursson, T., Krøll, J. B., Neergård, T. B., Jepsen, J., Roepstorff, P., Kristiansen, Karsten, Poulsen, F. M., Knudsen, J. & Stenvang, Jan, 1999, In: Biochemistry. 38, 8, p. 2386-94 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    A phase II study of weekly irinotecan in patients with locally advanced or metastatic HER2- negative breast cancer and increased copy numbers of the topoisomerase 1 (TOP1) gene: a study protocol

    Kümler, Iben, Balslev, E., Stenvang, Jan, Brünner, N. & Nielsen, D., 2015, In: B M C Cancer. 15, 5 p., 78.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Two open-label, single arm, non-randomized phase II studies of irinotecan for the treatment of metastatic breast cancer in patients with increased copy number of the topoisomerase i gene

    Kümler, I., Balslev, E., Stenvang, Jan, Brünner, N., Ejlertsen, Bent Laursen, Jakobsen, E. H. & Nielsen, D. L., Jun 2019, In: BMC Cancer. 19, 5 p., 573.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Drug transporters in breast cancer: response to anthracyclines and taxanes

    Kümler, I., Stenvang, Jan, Moreira, José, Brünner, N. & Nielsen, Dorte Lisbet, Sep 2015, In: Expert Review of Anticancer Therapy. 15, 9, p. 1075-1092 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Topoisomerase-1 gene copy aberrations are frequent in patients with breast cancer

    Kümler, I., Balslev, E., Poulsen, T. S., Nielsen, Signe Lykke, Nygård, S. B., Rømer, M. U., Christensen, I. J., Høgdall, E., Moreira, José, Nielsen, Dorte Lisbet, Brünner, N. & Stenvang, Jan, 8 Apr 2015, In: International Journal of Cancer. 137, 8, p. 2000-2006 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    A systematic review on topoisomerase 1 inhibition in the treatment of metastatic breast cancer

    Kümler, I., Brünner, N., Stenvang, Jan, Balslev, E. & Nielsen, D. L., 2013, In: Breast Cancer Research and Treatment. 138, 2, p. 347-358 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Targeting anti-cancer drug resistance in gastro-intestinal cancer: Inhibition of the SRPK1 kinase and degradation of the ABCG2 drug efflux pump

    Ladekarl, M., Schou, J. H. V., Roest, N. L., Stenvang, Jan, Brunner, N. & Vestlev, P. M., Sep 2020, p. S503-S504. 2 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  18. Published

    No effect of ablation of surfactant protein-D on acute cerebral infarction in mice

    Lambertsen, K. L., Østergaard, K., Clausen, B. H., Hansen, S., Stenvang, Jan, Thorsen, S. B., Meldgaard, M., Kristensen, B. W., Hansen, P. B. L., Sørensen, G. L. & Finsen, B., 2014, In: Journal of Neuroinflammation. 11, 13 p., 123.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Molecular Profiling of Docetaxel-Resistant Prostate Cancer Cells Identifies Multiple Mechanisms of Therapeutic Resistance

    Lima, T. S., Iglesias Gato, Diego, De Oliveira Souza, Luciano, Stenvang, Jan, Lima, D. S., Røder, Andreas, Brasso, K. & Moreira, José, 2021, In: Cancers. 13, 19 p.

    Research output: Contribution to journalJournal articleResearch

  20. Published

    Integrative analyses of gene expression and DNA methylation profiles in breast cancer cell line models of tamoxifen-resistance indicate a potential role of cells with stem-like properties

    Lin, X., Li, J., Yin, G., Zhao, Q., Elias, D., Lykkesfeldt, A., Stenvang, Jan, Brünner, N., Wang, J., Yang, H., Bolund, L. & Ditzel, H. J., 2013, In: Breast cancer research : BCR. 15, 6, 17 p., R119.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    The potential role of Alu Y in the development of resistance to SN38 (Irinotecan) or oxaliplatin in colorectal cancer

    Lin, X., Stenvang, Jan, Rasmussen, M. H., Zhu, S., Jensen, N. F., Tarpgaard, L. S., Yang, G., Belling, K., Andersen, C. L., Li, J., Bolund, L. & Brünner, N., 2015, In: BMC Genomics. 16, 17 p., 404.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Multiplexed homogeneous proximity ligation assays for high throughput protein biomarker research in serological material

    Lundberg, M., Thorsen, S. B., Assarsson, E., Villablanca, A., Tran, B., Gee, N., Knowles, M., Nielsen, B. E. S., Couto, E. G., Martin, R., Nilsson, O., Fermer, C., Schlingemann, J., Christensen, I. J., Nielsen, H. J., Ekstrom, B., Andersson, C., Gustafsson, M., Brünner, N., Stenvang, J. & 1 others, Fredriksson, S., Apr 2011, In: Molecular and Cellular Proteomics. 10

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Therapeutic application of multipotent stem cells

    Mirzaei, H., Sahebkar, A., Sichani, L. S., Moridikia, A., Nazari, S., Sadri Nahand, J., salehi, H., Stenvang, Jan, Masoudifar, A., Mirzaei, H. R. & Jaafari, M. R., 2018, In: Journal of Cellular Physiology. 233, 4, p. 2815–2823

    Research output: Contribution to journalReviewResearchpeer-review

  24. Published

    State of the art in microRNA as diagnostic and therapeutic biomarkers in chronic lymphocytic leukemia

    Mirzaei, H., Fathullahzadeh, S., Khanmohammadi, R., Darijani, M., Momeni, F., Masoudifar, A., Goodarzi, M., Mardanshah, O., Stenvang, Jan, Jaafari, M. R. & Mirzaei, H. R., Feb 2018, In: Journal of Cellular Physiology. 233, 2, p. 888-900 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  25. Published

    Proximity probing assays for simultaneous visualization of protein complexes in situ

    Moreira, José, Thorsen, S. B., Brünner, N. & Stenvang, Jan, 2013, In: Expert Review of Proteomics. 10, 3, p. 219-221 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 12922