Jan Stenvang

Jan Stenvang

Associate Professor

ORCID: 0000-0001-5647-4828

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  1. Published

    Identification and characterization of a new TIMP-1 binding protein

    Moreira, José, Høeberg, M., Lademann, U. A., Viuff, B. M., Jensen, L. V., Stenvang, Jan, Nygård, S. B., Ørum-Madsen, M. S., Vistesen, M. V., Fuglsang, Anja Thoe, Liu, S. & Brünner, N., 2015, In: Cancer Research. 75, 9 suppl., 1 p., Abstract P5-07-08.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  2. Published

    Implications of ABCG2 Expression on Irinotecan Treatment of Colorectal Cancer Patients: A Review

    Nielsen, Dorte Lisbet, Palshof, J. A., Bruenner, N., Stenvang, Jan & Viuff, B. M., Sep 2017, In: International Journal of Molecular Sciences (Online). 18, 9, 16 p., 1926.

    Research output: Contribution to journal › Review › Research › peer-review

  3. Published

    Metallopeptidase Inhibitor 1 (TIMP-1) promotes receptor tyrosine kinase c-Kit signaling in colorectal cancer

    Nordgaard, C., Doll, S., Matos, A. L. D. S. A., Høeberg, M., Kazi, J. U., Friis, S., Stenvang, Jan, Rönnstrand, L., Mann, Matthias & Moreira, José, 2019, In: Molecular Oncology. 13, 12, p. 2646-2662

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Pharmacodynamic modelling reveals synergistic interaction between docetaxel and SCO-101 in a docetaxel-resistant triple negative breast cancer cell line

    Nøhr-Nielsen, A., Bagger, Sofie Morsing, Brünner, N., Stenvang, Jan & Lund, Trine Meldgaard, 2020, In: European Journal of Pharmaceutical Sciences. 148, 10 p., 105315.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Silencing of microRNA families by seed-targeting tiny LNAs

    Obad, S., dos Santos, C. O., Petri, A., Heidenblad, M., Broom, O., Ruse, C., Fu, C., Lindow, M., Stenvang, Jan, Straarup, E. M., Hansen, H. F., Koch, T., Pappin, D., Hannon, G. J. & Kauppinen, S., 2011, In: Nature Genetics. 43, 4, p. 371-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    miRNA profiling of circulating EpCAM(+) extracellular vesicles: promising biomarkers of colorectal cancer

    Ostenfeld, M. S., Jensen, S. G., Jeppesen, D. K., Christensen, L., Thorsen, S. B., Stenvang, Jan, Hvam, M. L., Thomsen, A., Mouritzen, P., Rasmussen, M. H., Nielsen, H. J., Ørntoft, T. F. & Andersen, C. L., 2016, In: Journal of Extracellular Vesicles. 5, 14 p., 31488.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    ABCG2 Protein Levels and Association to Response to First-Line Irinotecan-Based Therapy for Patients with Metastatic Colorectal Cancer

    Palshof, J. A., Cederbye, C. N., Hgdall, E. V. S., Poulsen, T. S., Linnemann, D., Nygaard, S. B., Stenvang, Jan, Christensen, I. J., Jensen, B. V., Pfeiffer, P., Brunner, N., Yilmaz, M., Viuff, B. M. & Nielsen, Dorte Lisbet, 2020, In: International Journal of Molecular Sciences. 21, 14, 13 p., 5027.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Topoisomerase I copy number alterations as biomarker for irinotecan efficacy in metastatic colorectal cancer

    Palshof, J. A., Høgdall, Estrid Vilma Solyom, Poulsen, T. S., Linnemann, D., Jensen, B. V., Pfeiffer, P., Tarpgaard, L. S., Brunner, N., Stenvang, Jan, Yilmaz, M. & Nielsen, Dorte Lisbet, 11 Jan 2017, In: BMC Cancer. 17, 10 p., 48.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Reversal of ABCG2/BCRP-mediated multidrug resistance by 5,3’,5’-trihydroxy-3,6,7,4’-tetramethoxyflavone isolated from the Australian desert plant Eremophila galeata Chinnock

    Petersen, M. J., Lund, X. L., Semple, S. J., Buirchell, B., Franzyk, Henrik, Gajhede, Michael, Kongstad, Kenneth Thermann, Stenvang, Jan & Stærk, Dan, 2021, In: Biomolecules. 11, 10, 19 p., 1534.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    A novel dual-target steroid sulfatase inhibitor and antiestrogen: SR 16157, a promising agent for the therapy of breast cancer

    Rasmussen, L. M., Zaveri, N. T., Stenvang, Jan, Peters, R. H. & Lykkesfeldt, A. E., 2007, In: Breast Cancer Research and Treatment. 106, 2, p. 191-203 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    High expression of microRNA-625-3p is associated with poor response to first-line oxaliplatin based treatment of metastatic colorectal cancer

    Rasmussen, M. H., Jensen, N. F., Tarpgaard, L. S., Qvortrup, C., Rømer, M. U. K., Stenvang, Jan, Hansen, T. P., Christensen, L. L., Lindebjerg, J., Hansen, F., Jensen, B. V., Hansen, T. F., Pfeiffer, P., Brünner, N., Ørntoft, T. F. & Andersen, C. L., 2013, In: Molecular Oncology. 7, 3, p. 637-646 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    MicroRNAs, epigenetics and disease

    Silahtaroglu, Asli & Stenvang, Jan, 2010, In: Essays in Biochemistry. 48, 1, p. 165-185 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Measuring ERCC1 protein expression in cancer specimens: validation of a novel antibody

    Smith, D. H., Fiehn, A. K., Fogh, L., Christensen, I. J., Hansen, T. P., Stenvang, Jan, Nielsen, H. J., Nielsen, K. V., Hasselby, J. P., Brünner, N. & Jensen, S. S., 2014, In: Scientific Reports. 4, p. 1-8 8 p., 4313.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. MiR-155 is overexpressed in patients with atopic dermatitis and modulates T-cell proliferative responses by targeting cytotoxic T lymphocyte–associated antigen 4

    Sonkoly , E., Janson , P., Majuri , M., Savinko , T., Fyhrquist , N., Eidsmo , L., Xu , N., Meisgen , F., Wei , T., Bradley , M., Stenvang, Jan, Kauppinen , S., Alenius, H., Lauerma , A., Homey , B., Winqvist , O., Ståhle , M. & Pivarcsi , A., 2010, In: Journal of Allergy and Clinical Immunology. 126, 3, p. 581-589.e20 29 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Antibody-drug conjugates (ADCs) targeting trophoblast cell surface antigen 2 (Trop-2) and precision treatment of breast cancer

    Stenvang, Jan, Vestlev, P. M., Jensen, B. V. & Pfeiffer, P., 2022, In: Annals of Translational Medicine. 10, 21, 4 p., 1184.

    Research output: Contribution to journal › Editorial › Research › peer-review

  16. Published

    MicroRNAs as targets for antisense-based therapeutics

    Stenvang, Jan & Kauppinen, M. S., 2008, In: Expert Opinion on Biological Therapy. 8, 1, p. 59-81 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    The utility of LNA in microRNA-based cancer diagnostics and therapeutics

    Stenvang, Jan, Silahtaroglu, Asli, Lindow, M., Elmen, J. & Kauppinen, S., 2008, In: Seminars in Cancer Biology. 18, 2, p. 89-102 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Targeting of microRNAs for therapeutics

    Stenvang, Jan, Lindow, M. & Kauppinen, S., 2008, In: Biochemical Society Transactions. 36, Pt 6, p. 1197-200 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Biomarker-guided repurposing of chemotherapeutic drugs for cancer therapy: a novel strategy in drug development

    Stenvang, Jan, Kümler, I., Nygård, S. B., Smith, D. H., Nielsen, D., Brünner, N. & Moreira, José, 2013, In: Frontiers in Oncology. 3, 9 p., 313.

    Research output: Contribution to journal › Review › Research › peer-review

  20. Downregulation of p21(WAF1/CIP1) and estrogen receptor alpha in MCF-7 cells by antisense oligonucleotides containing locked nucleic acid (LNA)

    Stenvang, Jan, Pfundheller, H. M. & Lykkesfeldt, A. E., 2004, In: Oligonucleotides. 14, 2, p. 147-56 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Locked nucleic acid: a potent nucleic acid analog in therapeutics and biotechnology

    Stenvang, Jan, Sørensen, M. D. & Wengel, J., 2004, In: Oligonucleotides. 14, 2, p. 130-46 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Inhibition of microRNA function by antimiR oligonucleotides

    Stenvang, Jan, Petri, A., Lindow, M., Obad, S. & Kauppinen, S., 2012, In: Silence. 3, 1, 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    An Explorative Analysis of ABCG2/TOP-1 mRNA Expression as a Biomarker Test for FOLFIRI Treatment in Stage III Colon Cancer Patients: Results from Retrospective Analyses of the PETACC-3 Trial

    Stenvang, Jan, Budinská, E., van Cutsem, E., Bosman, F., Popovici, V. & Brünner, N., 2020, In: Cancers. 12, 4, 12 p., 977.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. LNA-antisense rivals siRNA for gene silencing

    Stenvang, Jan & Wengel, J., Mar 2004, In: Current Opinion in Drug Discovery & Development. 7, 2, p. 188-94 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Topoisomerase-1 and -2A gene copy numbers are elevated in mismatch repair-proficient colorectal cancers

    Sønderstrup, I. M. H., Nygård, S. B., Poulsen, T. S., Linnemann, D., Stenvang, Jan, Nielsen, H. J., Bartek, J., Brünner, N., Nørgaard, P. & Riis, Lene Buhl, 4 Mar 2015, In: Molecular Oncology. 9, 6, p. 1207-1217 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    A phase II study of Epirubicin in oxaliplatin-resistant patients with metastatic colorectal cancer and TOP2A gene amplification

    Tarpgaard, L. S., Qvortrup, C., Nygård, S. B., Nielsen, Signe Lykke, Andersen, D. R., Jensen, N. F., Stenvang, Jan, Detlefsen, S., Brünner, N. & Pfeiffer, P., 2016, In: B M C Cancer. 16, 5 p., 91.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    New use for old drugs: Epirubicin in colorectal cancer

    Tarpgaard, L. S., Qvortrup, C., Nielsen, S. L., Stenvang, Jan, Detlefsen, S., Brunner, N. & Pfeiffer, P., 2021, In: Acta Oncologica. 60, 7, p. 954-956 3 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  28. Published

    The therapeutic potential of MicroRNAs in cancer

    Thorsen, S. B., Obad, S., Jensen, N. F., Stenvang, Jan & Kauppinen, S., 2012, In: Cancer Journal. 18, 3, p. 275-284 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Plasma levels of the MMP-9:TIMP-1 complex as prognostic biomarker in breast cancer: a retrospective study

    Thorsen, S. B., Christensen, Sarah Louise T, Würtz, S. Ø., Lundberg, M., Nielsen, B. E. S., Jensen, L. V., Knowles, M., Gee, N., Fredriksson, S., Møller, S., Brünner, N., Rasmussen, A. S. & Stenvang, Jan, 2013, In: B M C Cancer. 13, 12 p., 598.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Gel-Based Proteomics of Clinical Samples Identifies Potential Serological Biomarkers for Early Detection of Colorectal Cancer

    Thorsen, S. F., Gromova, I., Christensen, I. J., Fredriksson, S., Andersen, C. L., Nielsen, H. J., Stenvang, Jan & Moreira, José, Dec 2019, In: International Journal of Molecular Sciences (Online). 20, 19 p., 6082.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Modulation of CpG oligodeoxynucleotide-mediated immune stimulation by locked nucleic acid (LNA)

    Vollmer, J., Uhlmann, E., Stenvang, Jan, Schetter, C., Jurk, M., Wader, T., Wüllner, M. & Krieg, A. M., 2004, In: Oligonucleotides. 14, 1, p. 23-31 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Induction of cell death in antiestrogen resistant human breast cancer cells by the protein kinase CK2 inhibitor DMAT

    Yde, C. W., Frogne, T., Lykkesfeldt, A. E., Fichtner, I., Issinger, O. G. & Stenvang, Jan, 2007, In: Cancer Letters. 256, 2, p. 229-237 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Breast cancer cells with acquired antiestrogen resistance are sensitized to cisplatin-induced cell death

    Yde, C. W., Gyrd-Hansen, Mads, Lykkesfeldt, A. E., Issinger, O. & Stenvang, Jan, Jun 2007, In: Molecular Cancer Therapeutics. 6, 6, p. 1869-1876 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Metagenomic analysis of faecal microbiome as a tool towards targeted non-invasive biomarkers for colorectal cancer

    Yu, J., Feng, Q., Wong, S. H., Zhang, D., Liang, Q. Y., Qin, Y., Tang, L., Zhao, H., Stenvang, J., Li, Y., Wang, X., Xu, X., Chen, N., Wu, W. K. K., Al-Aama, J., Nielsen, H. J., Kiilerich, P., Jensen, B. A. H., Yau, T. O., Lan, Z. & 19 others, Jia, H., Li, J., Xiao, L., Lam, T. Y. T., Ng, S. C., Cheng, A. S., Wong, V. W., Chan, F. K. L., Xu, X., Yang, H., Madsen, L., Datz, C., Tilg, H., Wang, J., Brünner, N., Kristiansen, Karsten, Arumugam, Mani, Sung, J. J. & Wang, J., 2017, In: Gut. 66, p. 70-78 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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