Jan Stenvang
Associate Professor
Translational and Clinical Pharmacology
Jagtvej 160
2100 København Ø
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Progesterone receptor isoform A may regulate the effects of neoadjuvant aglepristone in canine mammary carcinoma
Guil-Luna, S., Stenvang, Jan, Brünner, N., De Andrés, F. J., Rollón, E., Domingo, V., Sánchez-Céspedes, R., Millán, Y. & Mulas, J. M. D. L., 2014, In: B M C Veterinary Research. 10, 8 p., 296.Research output: Contribution to journal › Journal article › Research › peer-review
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Progesterone receptor isoform analysis by quantitative real-time polymerase chain reaction in formalin-fixed, paraffin-embedded canine mammary dysplasias and tumors
Guil-Luna, S., Stenvang, Jan, Brünner, N., Sánchez-Céspedes, R., Millán, Y., Gómez-Laguna, J. & Mulas, J. M. D. L., 2014, In: Veterinary Pathology. 51, 5, p. 895-902 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Protein kinase C alpha is a marker for antiestrogen resistance and is involved in the growth of tamoxifen resistant human breast cancer cells
Frankel, Lisa, Lykkesfeldt, A. E., Hansen, J. B. H. & Stenvang, Jan, 2007, In: Breast Cancer Research and Treatment. 104, 2, p. 165-179 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proximity probing assays for simultaneous visualization of protein complexes in situ
Moreira, José, Thorsen, S. B., Brünner, N. & Stenvang, Jan, 2013, In: Expert Review of Proteomics. 10, 3, p. 219-221 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Purification and characterization of bioactive his6-tagged recombinant human tissue inhibitor of metalloproteinases-1 (TIMP-1) protein expressed at high yields in mammalian cells
Jensen, L. V., Lademann, U. A., Andersen, E. V., Højrup, P., Thaysen-Andersen, M., Krogh, B. O., Viuff, B. M., Brünner, N., Stenvang, Jan & Moreira, José, 2014, In: Protein Expression and Purification. 101, p. 157-164 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Repurposing Cationic Amphiphilic Antihistamines for Cancer Treatment
Ellegaard, A., Dehlendorff, C., Vind, Anna Constance, Anand, A., Kristiansen, Luise Cederkvist, Petersen, N. H. T., Nylandsted, J., Stenvang, Jan, Mellemgaard, A., Osterlind, K., Friis, S. & Jaattela, Marja, Jul 2016, In: EBioMedicine. 9, p. 130-139 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reversal of ABCG2/BCRP-mediated multidrug resistance by 5,3’,5’-trihydroxy-3,6,7,4’-tetramethoxyflavone isolated from the Australian desert plant Eremophila galeata Chinnock
Petersen, M. J., Lund, X. L., Semple, S. J., Buirchell, B., Franzyk, Henrik, Gajhede, Michael, Kongstad, Kenneth Thermann, Stenvang, Jan & Stærk, Dan, 2021, In: Biomolecules. 11, 10, 19 p., 1534.Research output: Contribution to journal › Journal article › Research › peer-review
Sequential versus combined treatment of human breast cancer cells with antiestrogens and the vitamin D analogue EB1089 and evaluation of predictive markers for vitamin D treatment.
Christensen, G. L., Stenvang, Jan, Fog, C. K., Christensen, I. J. & Lykkesfeldt, A. E., 2004, In: Breast Cancer Research and Treatment. p. 53–63Research output: Contribution to journal › Journal article › Research › peer-review
Silencing of microRNA families by seed-targeting tiny LNAs
Obad, S., dos Santos, C. O., Petri, A., Heidenblad, M., Broom, O., Ruse, C., Fu, C., Lindow, M., Stenvang, Jan, Straarup, E. M., Hansen, H. F., Koch, T., Pappin, D., Hannon, G. J. & Kauppinen, S., 2011, In: Nature Genetics. 43, 4, p. 371-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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State of the art in microRNA as diagnostic and therapeutic biomarkers in chronic lymphocytic leukemia
Mirzaei, H., Fathullahzadeh, S., Khanmohammadi, R., Darijani, M., Momeni, F., Masoudifar, A., Goodarzi, M., Mardanshah, O., Stenvang, Jan, Jaafari, M. R. & Mirzaei, H. R., Feb 2018, In: Journal of Cellular Physiology. 233, 2, p. 888-900 13 p.Research output: Contribution to journal › Review › Research › peer-review
Synthesis and biological evaluation of branched and conformationally restricted analogs of the anticancer compounds 3'-C-ethynyluridine (EUrd) and 3'-C-ethynylcytidine (ECyd)
Hrdlicka, P. J., Andersen, N. K., Stenvang, Jan, Hansen, F. G., Haselmann, K. F., Nielsen, C. & Wengel, J., 1 Apr 2005, In: Bioorganic & Medicinal Chemistry. 13, 7, p. 2597-621 25 p.Research output: Contribution to journal › Journal article › Research › peer-review
Synthesis and biological evaluation of conformationally restricted and nucleobase-modified analogs of the anticancer compound 3'-C-ethynylcytidine (ECyd)
Hrdlicka, P. J., Stenvang, Jan & Wengel, J., 2005, In: Nucleosides, nucleotides & nucleic acids. 24, 5-7, p. 397-400 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Synthesis and biological evaluation of nucleobase-modified analogs of the anticancer compounds 3'-C-ethynyluridine (EUrd) and 3'-C-ethynylcytidine (ECyd)
Hrdlicka, P. J., Jepsen, J. S., Nielsen, C., Wengel, J. & Stenvang, Jan, 15 Feb 2005, In: Bioorganic & Medicinal Chemistry. 13, 4, p. 1249-60 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Synthesis of thiazole linked chalcones and their pyrimidine analogues as anticancer agents
Kesari, C., Rama, K. R., Sedighi, K., Stenvang, Jan, Björkling, Fredrik, Kankala, S. & Thota, N., 2021, In: Synthetic Communications. 51, 9, p. 1406-1416 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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TIMP-1 increases expression and phosphorylation of proteins associated with drug resistance in breast cancer cells
Hekmat, O., Munk, S., Fogh, L., Yadav, R., Francavilla, C., Horn, H., Würtz, S. Ø., Schrohl, A-S., Damsgaard, B., Romer, M. U., Belling, K., Jensen, N. F., Gromova, I., Bekker-Jensen, D. B., Moreira, J., Jensen, L. J., Gupta, R., Lademann, U. A., Brünner, N., Olsen, J. V. & 1 others, , 5 Aug 2013, In: Journal of Proteome Research. 12, 9, p. 4136-4151 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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TIMP-1 overexpression does not affect sensitivity to HER2-targeting drugs in the HER2-gene-amplified SK-BR-3 human breast cancer cell line
Deng, X., Fogh, L., Lademann, U. A., Jensen, V., Stenvang, Jan, Yang, H., Brünner, N. & Rasmussen, A. S., 2013, In: Tumor Biology. 34, 2, p. 1161-1170 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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TIMP1 overexpression mediates resistance of MCF-7 human breast cancer cells to fulvestrant and down-regulates progesterone receptor expression
Bjerre, C. A., Jensen, L. V., Belling, K. C., Würtz, S. Ø., Yadav, R., Lademann, U. A., Rigina, O., Do, K. N., Ditzel, H. J., Lykkesfeldt, A. E., Wang, J., Nielsen, H. B., Brünner, N., Gupta, R., Rasmussen, A. S. & Stenvang, Jan, 2013, In: Tumor Biology. 34, 6, p. 3839-3851 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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TOP1 gene copy numbers are increased in cancers of the bile duct and pancreas
Grunnet, M., Calatayud, D., Schultz, N. A., Hasselby, Jane Preuss, Mau-Sørensen, M., Brünner, N. & Stenvang, Jan, 2015, In: Scandinavian Journal of Gastroenterology. 50, 4, p. 485-494 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Targeting anti-cancer drug resistance in gastro-intestinal cancer: Inhibition of the SRPK1 kinase and degradation of the ABCG2 drug efflux pump
Ladekarl, M., Schou, J. H. V., Roest, N. L., Stenvang, Jan, Brunner, N. & Vestlev, P. M., Sep 2020, p. S503-S504. 2 p.Research output: Contribution to conference › Conference abstract for conference › Research
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Targeting of microRNAs for therapeutics
Stenvang, Jan, Lindow, M. & Kauppinen, S., 2008, In: Biochemical Society Transactions. 36, Pt 6, p. 1197-200 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Pyrazolo[3,4-d]pyrimidine Derivative, SCO-201, Reverses Multidrug Resistance Mediated by ABCG2/BCRP
Ambjørner, S. E. B., Wiese, M., Köhler, S. C., Svindt, J., Lund, X. L., Gajhede, Michael, Saaby, Lasse, Larsen, Birger Brodin, Rump, S., Weigt, H., Brünner, N. & Stenvang, Jan, 4 Mar 2020, In: Cells. 9, 3, 22 p., 613.Research output: Contribution to journal › Journal article › Research › peer-review
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The glutamate transport inhibitor DL-Threo-β-Benzyloxyaspartic acid (DL-TBOA) differentially affects SN38- and oxaliplatin-induced death of drug-resistant colorectal cancer cells
Cuesta, E. P., Christensen, S., Jensen, Anders A., Jensen, N. F., Bunch, Lennart, Rømer, M. U. K., Brünner, N., Stenvang, Jan & Pedersen, Stine Helene Falsig, 2015, In: B M C Cancer. 15, 1, 17 p., 411.Research output: Contribution to journal › Journal article › Research › peer-review
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The invariant chain CD74 protein is a cell surface binding partner of TIMP-1 in breast cancer cells
Høeberg, M., Noer, Julie Boertmann, Vistesen, M. V., Bartels, Annette Snejbjerg, Bech, E. M., Nygård, S. B., Lademann, U., Stenvang, Jan, Liu, S., Fuglsang, Anja Thoe, Brünner, N. & Moreira, José, 2023, In: Molecular Oncology. 17, 8, p. 1595-1612Research output: Contribution to journal › Journal article › Research › peer-review
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The potential role of Alu Y in the development of resistance to SN38 (Irinotecan) or oxaliplatin in colorectal cancer
Lin, X., Stenvang, Jan, Rasmussen, M. H., Zhu, S., Jensen, N. F., Tarpgaard, L. S., Yang, G., Belling, K., Andersen, C. L., Li, J., Bolund, L. & Brünner, N., 2015, In: BMC Genomics. 16, 17 p., 404.Research output: Contribution to journal › Journal article › Research › peer-review
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The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells
Hansen, S. N., Ehlers, Natasja Spring, Zhu, S., Thomsen, M. B. H., Nielsen, R. L., Liu, D., Wang, G., Hou, Y., Zhang, X., Xu, X., Bolund, L., Yang, H., Wang, J., Moreira, José, Ditzel, H. J., Brünner, N., Rasmussen, A. S., Stenvang, Jan & Gupta, R., 9 Jun 2016, In: B M C Genomics. 17, 15 p., 442.Research output: Contribution to journal › Journal article › Research › peer-review
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The therapeutic potential of MicroRNAs in cancer
Thorsen, S. B., Obad, S., Jensen, N. F., Stenvang, Jan & Kauppinen, S., 2012, In: Cancer Journal. 18, 3, p. 275-284 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The utility of LNA in microRNA-based cancer diagnostics and therapeutics
Stenvang, Jan, Silahtaroglu, Asli, Lindow, M., Elmen, J. & Kauppinen, S., 2008, In: Seminars in Cancer Biology. 18, 2, p. 89-102 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Therapeutic application of multipotent stem cells
Mirzaei, H., Sahebkar, A., Sichani, L. S., Moridikia, A., Nazari, S., Sadri Nahand, J., salehi, H., Stenvang, Jan, Masoudifar, A., Mirzaei, H. R. & Jaafari, M. R., 2018, In: Journal of Cellular Physiology. 233, 4, p. 2815–2823Research output: Contribution to journal › Review › Research › peer-review
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Topoisomerase I copy number alterations as biomarker for irinotecan efficacy in metastatic colorectal cancer
Palshof, J. A., Høgdall, Estrid Vilma Solyom, Poulsen, T. S., Linnemann, D., Jensen, B. V., Pfeiffer, P., Tarpgaard, L. S., Brunner, N., Stenvang, Jan, Yilmaz, M. & Nielsen, Dorte Lisbet, 11 Jan 2017, In: BMC Cancer. 17, 10 p., 48.Research output: Contribution to journal › Journal article › Research › peer-review
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Topoisomerase-1 and -2A gene copy numbers are elevated in mismatch repair-proficient colorectal cancers
Sønderstrup, I. M. H., Nygård, S. B., Poulsen, T. S., Linnemann, D., Stenvang, Jan, Nielsen, H. J., Bartek, J., Brünner, N., Nørgaard, P. & Riis, Lene Buhl, 4 Mar 2015, In: Molecular Oncology. 9, 6, p. 1207-1217 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Topoisomerase-1 gene copy aberrations are frequent in patients with breast cancer
Kümler, I., Balslev, E., Poulsen, T. S., Nielsen, Signe Lykke, Nygård, S. B., Rømer, M. U., Christensen, I. J., Høgdall, E., Moreira, José, Nielsen, Dorte Lisbet, Brünner, N. & Stenvang, Jan, 8 Apr 2015, In: International Journal of Cancer. 137, 8, p. 2000-2006 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Two open-label, single arm, non-randomized phase II studies of irinotecan for the treatment of metastatic breast cancer in patients with increased copy number of the topoisomerase i gene
Kümler, I., Balslev, E., Stenvang, Jan, Brünner, N., Ejlertsen, Bent Laursen, Jakobsen, E. H. & Nielsen, D. L., Jun 2019, In: BMC Cancer. 19, 5 p., 573.Research output: Contribution to journal › Journal article › Research › peer-review
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lncRNA profile study reveals the mRNAs and lncRNAs associated with docetaxel resistance in breast cancer cells
Huang, P., Li, F., Li, L., You, Y., Luo, S., Dong, Z., Gao, Q., Wu, S., Brünner, N. & Stenvang, Jan, 1 Dec 2018, In: Scientific Reports. 8, 1, 17970.Research output: Contribution to journal › Journal article › Research › peer-review
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miRNA profiling of circulating EpCAM(+) extracellular vesicles: promising biomarkers of colorectal cancer
Ostenfeld, M. S., Jensen, S. G., Jeppesen, D. K., Christensen, L., Thorsen, S. B., Stenvang, Jan, Hvam, M. L., Thomsen, A., Mouritzen, P., Rasmussen, M. H., Nielsen, H. J., Ørntoft, T. F. & Andersen, C. L., 2016, In: Journal of Extracellular Vesicles. 5, 14 p., 31488.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 12922
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MicroRNAs, epigenetics and disease
Research output: Contribution to journal › Journal article › Research › peer-review
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Measuring ERCC1 protein expression in cancer specimens: validation of a novel antibody
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Progesterone receptor isoform A may regulate the effects of neoadjuvant aglepristone in canine mammary carcinoma
Research output: Contribution to journal › Journal article › Research › peer-review
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