Jesper M. Mathiesen
Associate Professor
Molecular and Cellular Pharmacology
Jagtvej 160
2100 København Ø
- Published
Pharmacological characterization and modeling of the binding sites of novel 1,3-bis(pyridinylethynyl)benzenes as metabotropic glutamate receptor 5-selective negative allosteric modulators
Mølck, C., Harpsøe, Kasper, Gloriam, David E., Clausen, Rasmus Prætorius, Madsen, Ulf, Pedersen, L., Jimenez, H. N., Nielsen, S. M., Mathiesen, Jesper M. & Bräuner, Hans, 2012, In: Molecular Pharmacology. 82, 5, p. 929-37 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
mGluR5: Exploration of Orthosteric and Allosteric Ligand Binding Pockets and Their Applications to Drug Discovery
Mølck, C., Harpsøe, Kasper, Gloriam, David E., Mathiesen, Jesper M., Nielsen, S. M. & Bräuner, Hans, Oct 2014, In: Neurochemical Research. 39, 10, p. 1862-1875 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells
Møller, T. C., Pedersen, M. F., van Senten, Jeffrey Roy, Seiersen, S. D., Mathiesen, Jesper M., Bouvier, M. & Bräuner, Hans, 2020, In: Scientific Reports. 10, 1, 13 p., 17395.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structures of metabotropic GABAB receptor
Papasergi-Scott, M. M., Robertson, M. J., Seven, A. B., Panova, O., Mathiesen, Jesper M. & Skiniotis, G., 2020, In: Nature. 584, 7820, p. 310-314 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Crystal structure of the β2 adrenergic receptor-Gs protein complex
Rasmussen, Søren Gøgsig Faarup, DeVree, B. T., Zou, Y., Kruse, A. C., Chung, K. Y., Kobilka, T. S., Thian, F. S., Chae, P. S., Pardon, E., Calinski, D., Mathiesen, Jesper M., Shah, S. T. A., Lyons, J. A., Caffrey, M., Gellman, S. H., Steyaert, J., Skiniotis, G., Weis, W. I., Sunahara, R. K. & Kobilka, B. K., 29 Sep 2011, In: Nature. 477, 7366, p. 549-55 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular pharmacology and therapeutic prospects of metabotropic glutamate receptor allosteric modulators
Ritzén, A., Mathiesen, Jesper M. & Thomsen, C., 1 Oct 2005, In: Basic and Clinical Pharmacology and Toxicology. 97, 4, p. 202-213 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Real-time trafficking and signaling of the glucagon-like peptide-1 receptor
Roed, S. N., Wismann, P., Underwood, C. R., Kulahin, N., Iversen, H., Cappelen, K. A., Schäffer, L., Lehtonen, J., Hecksher-Soerensen, J., Secher, A., Mathiesen, Jesper M., Bräuner, Hans, Whistler, J. L., Knudsen, S. M. & Waldhoer, M., Feb 2014, In: Molecular and Cellular Endocrinology. 382, 2, p. 938-949 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glycine: a long-sought novel ligand for GPR158
Rosenkilde, Mette & Mathiesen, Jesper M., 2023, In: Trends in Pharmacological Sciences. 44, 8, p. 489-491Research output: Contribution to journal › Letter › Research › peer-review
- Published
The C-terminal tail of CRTH2 is a key molecular determinant that constrains GalphaI- and downstream-signaling cascade activation
Schroeder, R., Merten, N., Mathiesen, Jesper M., Martini, L., Letunic, A. K., Krop, F., Blaukat, A., Fang, Y., Tran, E., Ulven, Trond, Drewke, C., Whistler, J., Pardo, L., Gomeza, J. & Kostenis, E., 2009, In: Journal of Biological Chemistry. 284, 2, p. 1324-1336 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
G-protein activation by a metabotropic glutamate receptor
Seven, A. B., Barros-Álvarez, X., de Lapeyrière, M., Papasergi-Scott, M. M., Robertson, M. J., Zhang, C., Nwokonko, R. M., Gao, Y., Meyerowitz, J. G., Rocher, J. P., Schelshorn, D., Kobilka, B. K., Mathiesen, Jesper M. & Skiniotis, G., 2021, In: Nature. 595, p. 450-454Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4873159
Most downloads
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156
downloads
Gs protein peptidomimetics as allosteric modulators of the β2-adrenergic receptor
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
42
downloads
Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
25
downloads
Delineation of the GPR15 receptor-mediated Gα protein signalling profile in recombinant mammalian cells
Research output: Contribution to journal › Journal article › Research › peer-review
Published