José Moreira

José Moreira

Professor


  1. 1998
  2. Published

    Datin, a yeast poly(dA:dT)-binding protein, behaves as an activator of the wild-type ILV1 promoter and interacts synergistically with Reb1p

    Moreira, José, Remacle, J. E., Kielland-Brandt, M. & Holmberg, Steen, 1998, In: Molecular and General Genetics. 258, 1-2, p. 95-103 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published
  4. 1999
  5. Published

    Transcriptional repression of the yeast CHA1 gene requires the chromatin-remodeling complex RSC

    Moreira, José & Holmberg, Steen, 1999, In: E M B O Journal. 18, 10, p. 2836-44 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2000
  7. Published

    Chromatin-mediated transcriptional regulation by the yeast architectural factors NHP6A and NHP6B

    Moreira, José & Holmberg, Steen, 2000, In: EMBO Journal. 19, 24, p. 6804-6813 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2001
  9. Published

    Neither Reb1p nor poly(dA*T) elements are responsible for the highly specific chromatin organization at the ILV1 promoter

    Moreira, José, Hörz, W. & Holmberg, Steen, 2001, In: Journal of Biological Chemistry. 277, 5, p. 3202-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2003
  11. Published

    Integrating proteomic and functional genomic technologies in discovery-driven translational breast cancer research

    Celis, J. E., Gromov, P., Gromova, I., Moreira, J. M. A., Cabezón, T., Ambartsumian, N., Grigorian, M., Lukanidin, E., Thor Straten, P., Guldberg, P., Bartkova, J., Bartek, J., Lukas, J., Lukas, C., Lykkesfeldt, A., Jäättelä, M., Roepstorff, P., Bolund, L., Ørntoft, T. F., Brünner, N. & 5 others, Overgaard, J., Sandelin, K., Blichert-Toft, M., Mouridsen, H. & Rank, F. E., 2003, In: Molecular and Cellular Proteomics. 2, 6, p. 369-377 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    The histone deacetylase inhibitor Trichostatin A modulates CD4+ T cell responses

    Moreira, José, Scheipers, P. & Sørensen, P., 2003, In: B M C Cancer. 3, p. 30

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2004
  14. Expression of the tumor suppressor protein 14-3-3 sigma is down-regulated in invasive transitional cell carcinomas of the urinary bladder undergoing epithelial-to-mesenchymal transition

    Moreira, José, Gromov, P. & Celis, J. E., 2004, In: Molecular and Cellular Proteomics. 3, 4, p. 410-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Impact of proteomics on bladder cancer research

    Celis, J. E., Gromova, I., Moreira, José, Cabezon, T. & Gromov, P., 2004, In: Pharmacogenomics. 5, 4, p. 381-94 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Proteomic characterization of the interstitial fluid perfusing the breast tumor microenvironment: a novel resource for biomarker and therapeutic target discovery

    Celis, J. E., Gromov, P., Cabezón, T., Moreira, José, Ambartsumian, N., Sandelin, K., Rank, F. & Gromova, I., 2004, In: Molecular and Cellular Proteomics. 3, 4, p. 327-44 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2005
  18. Loss of expression of the adipocyte-type fatty acid-binding protein (A-FABP) is associated with progression of human urothelial carcinomas

    Ohlsson, G., Gromov, P., Sauter, G., Celis, J. E. & Moreira, José, 2005, In: Molecular and Cellular Proteomics. 4, 4, p. 570-581 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Towards discovery-driven translational research in breast cancer

    Celis, J. E., Moreira, José, Gromova, I., Cabezon, T., Ralfkiaer, U., Guldberg, P., Thor Straten, P., Mouridsen, H., Friis, E., Holm, D., Rank, F. & Gromov, P., 1 Jan 2005, In: FEBS Journal. 272, 1, p. 2-15 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  20. Published

    Down-regulation of the tumor suppressor protein 14-3-3σ is a sporadic event in cancer of the breast

    Moreira, José, Ohlsson, G., Rank, F. E. & Celis, J. E., 1 Apr 2005, In: Molecular and Cellular Proteomics. 4, 4, p. 555-569 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Identification of extracellular and intracellular signaling components of the mammary adipose tissue and its interstitial fluid in high risk breast cancer patients: Toward dissecting the molecular circuitry of epithelial-adipocyte stromal cell interactions

    Celis, J. E., Cabezón, T., Gromov, P., Friis, E., Rank, F., Gromova, I. & Moreira, José, 1 Apr 2005, In: Molecular and Cellular Proteomics. 4, 4, p. 492-522 31 p.

    Research output: Contribution to journalJournal articleResearch

  22. 2006
  23. Published

    Molecular pathology of breast apocrine carcinomas: A protein expression signature specific for benign apocrine metaplasia

    Celis, J. E., Gromova, I., Gromov, P., Cabezón, T., Friis, E., Rank, F. & Moreira, José, 2006, In: FEBS Letters. 580, 12, p. 2935-2944 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Apocrine cysts of the breast: Biomarkers, origin, enlargement, and relation with cancer phenotype

    Celis, J. E., Gromov, P., Moreira, José, Cabezón, T., Friis, E., Vejborg, I. M. M., Proess, G., Rank, F. & Gromova, I., 1 Mar 2006, In: Molecular and Cellular Proteomics. 5, 3, p. 462-483 22 p.

    Research output: Contribution to journalReviewResearchpeer-review

  25. Published

    Proteomic analysis of urinary fibrinogen degradation products in patients with urothelial carcinomas

    Gromov, P., Moreira, José, Gromova, I. & Celis, J. E., 1 Mar 2006, In: Clinical Proteomics. 2, 1-2, p. 45-66 22 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Determination of Antibody Specificity by Western Blotting

    Celis, J. E., Moreira, José & Gromov, P., 1 Dec 2006, Cell Biology, Four-Volume Set. Elsevier Science Inc., Vol. 1. p. 527-532 6 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  27. 2007
  28. Published

    Characterization of breast precancerous lesions and myoepithelial hyperplasia in sclerosing adenosis with apocrine metaplasia

    Celis, J. E., Gromova, I., Cabezón, T., Gromov, P., Shen, T., Timmermans, V. J. M., Rank, F. & Moreira, José, 2007, In: Molecular Oncology. 1, 1, p. 97-119 23 p.

    Research output: Contribution to journalJournal articleResearch

  29. Published

    Identification of a subset of breast carcinomas characterized by expression of cytokeratin 15: Relationship between CK15+ progenitor/amplified cells and pre-malignant lesions and invasive disease

    Celis, J. E., Gromova, I., Cabezón, T., Gromov, P., Shen, T., Timmermans-Wielenga, V., Rank, F. & Moreira, José, 1 Jan 2007, In: Molecular Oncology. 1, 3, p. 321-349 29 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. 2008
  31. Published

    A single lysis solution for the analysis of tissue samples by different proteomic technologies

    Gromov, P., Celis, J. E., Gromova, I., Rank, F., Timmermans, V. J. M. & Moreira, José, 2008, In: Molecular Oncology. 2, 4, p. 368-379 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. A combined proteome and ultrastructural localization analysis of 14-3-3 proteins in transformed human amnion (AMA) cells

    Shen, T., Ohlsson, G., Gromov, P., Gromova, I., Celis, J. E. & Moreira, José, 1 Jul 2008, In: Molecular and Cellular Proteomics. 7, 7, p. 1225-1240 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Proteomic strategies in bladder cancer: From tissue to fluid and back

    Gromov, P., Moreira, José, Gromova, I. & Celis, J. E., 1 Jul 2008, In: Proteomics - Clinical Applications. 2, 7-8, p. 974-988 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  34. Published

    Clinical proteomics

    Celis, J. E. & Moreira, José, 1 Oct 2008, In: Molecular and Cellular Proteomics. 7, 10, 1 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  35. 2009
  36. Published

    Molecular characterization of apocrine carcinoma of the breast: validation of an apocrine protein signature in a well-defined cohort

    Celis, J. E., Cabezon, T., Moreira, José, Gromov, P., Gromova, I., Timmermans-Wielenga, V., Iwase, T., Akiyama, F., Honma, N. & Rank, F., 2009, In: Molecular Oncology. 3, 3, p. 220-37

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. 2010
  38. Bladder cancer-associated protein, a potential prognostic biomarker in human bladder cancer

    Moreira, José, Ohlsson, G., Gromov, P., Simon, R., Sauter, G., Celis, J. E. & Gromova, I., 2010, In: Molecular & Cellular Proteomics. 9, 1, p. 161-77 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Tissue proteomics of the human mammary gland: towards an abridged definition of the molecular phenotypes underlying epithelial normalcy

    Moreira, José, Cabezón, T., Gromova, I., Gromov, P., Timmermans, V. J. M., Machado, I., Llombart-Bosch, A., Kroman, Niels Thorndahl, Rank, F. & Celis, J. E., 2010, In: Molecular Oncology. 4, 6, p. 539-561 23 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Challenges and Opportunities in Oncoproteomics

    Celis, J. E. & Moreira, José, 1 Jan 2010, In: Molecular Oncology. 4, 6, p. 459-460 2 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  41. Published

    Human mammary fibroblasts stimulate invasion of breast cancer cells in a three-dimensional culture and increase stroma development in mouse xenografts.

    Olsen, C. J., Moreira, José, Lukanidin, E. M. & Ambartsumian, N. S., 1 Jan 2010, In: BMC Cancer. 10, 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. 2012
  43. ErbB2-driven breast cancer cell invasion depends on a complex signaling network activating myeloid zinc finger-1-dependent cathepsin B expression

    Rafn, B., Nielsen, C. F., Andersen, S. H., Szyniarowski, P., Corcelle-Termeau, E., Valo, E., Fehrenbacher, N., Olsen, C. J., Daugaard, M., Egebjerg, C., Bøttzauw, T., Kohonen, P., Nylandsted, J., Hautaniemi, S., Moreira, José, Jaattela, M. & Kallunki, T., 2012, In: Molecular Cell. 45, 6, p. 764-776 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Immunoexpression analysis and prognostic value of BLCAP in breast cancer

    Gromova, I., Gromov, P., Kroman, N., Wielenga, V. T., Simon, R., Sauter, G. & Moreira, José, 2012, In: P L o S One. 7, 9, 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. 2013
  46. Published

    Biomarker-guided repurposing of chemotherapeutic drugs for cancer therapy: a novel strategy in drug development

    Stenvang, Jan, Kümler, I., Nygård, S. B., Smith, D. H., Nielsen, D., Brünner, N. & Moreira, José, 2013, In: Frontiers in Oncology. 3, 9 p., 313.

    Research output: Contribution to journalReviewResearchpeer-review

  47. Published

    Contribution of Na+,HCO3--cotransport to cellular pH control in human breast cancer: a role for the breast cancer susceptibility locus NBCn1 (SLC4A7)

    Bødtkjer, E., Moreira, José, Mele, M., Vahl, P., Wielenga, V. T., Christiansen, P. M., Jensen, V. E. D., Pedersen, Stine Helene Falsig & Aalkjær, C., 2013, In: International Journal of Cancer. 132, 6, p. 1288-1299 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Proteomic profiling of triple-negative breast carcinomas in combination with a three-tier orthogonal technology approach identifies Mage-A4 as potential therapeutic target in estrogen receptor negative breast cancer

    Cabezón, T., Gromova, I., Gromov, P., Serizawa, R. R., Wielenga, V. T., Kroman, Niels Thorndahl, Celis, J. E. & Moreira, José, 2013, In: Molecular & Cellular Proteomics. 12, 2, p. 381-394 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Proximity probing assays for simultaneous visualization of protein complexes in situ

    Moreira, José, Thorsen, S. B., Brünner, N. & Stenvang, Jan, 2013, In: Expert Review of Proteomics. 10, 3, p. 219-221 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Tumor interstitial fluid: a treasure trove of cancer biomarkers

    Gromov, P., Gromova, I., Olsen, C. J., Timmermans-Wielenga, V., Talman, M., Serizawa, R. R. & Moreira, José, 2013, In: B B A - Proteins and Proteomics. 1834, 11, p. 2259-2270 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    TIMP-1 increases expression and phosphorylation of proteins associated with drug resistance in breast cancer cells

    Hekmat, O., Munk, S., Fogh, L., Yadav, R., Francavilla, C., Horn, H., Würtz, S. Ø., Schrohl, A-S., Damsgaard, B., Romer, M. U., Belling, K., Jensen, N. F., Gromova, I., Bekker-Jensen, D. B., Moreira, J., Jensen, L. J., Gupta, R., Lademann, U. A., Brünner, N., Olsen, J. V. & 1 others, Stenvang, Jan, 5 Aug 2013, In: Journal of Proteome Research. 12, 9, p. 4136-4151 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. 2014
  53. Published

    CIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation: CIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation

    Puustinen, P., Rytter, A., Mortensen, M., Kohonen, P., Moreira, José & Jäättelä, M., 2014, In: Journal of Cell Biology. 204, 5, p. 713-727 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Comparative analysis of evolutionarily conserved motifs of epidermal growth factor receptor 2 (HER2) predicts novel potential therapeutic epitopes

    Deng, X., Zheng, X., Yang, H., Moreira, José, Brünner, N. & Christensen, Henrik, 2014, In: PLOS ONE. 9, 9, 9 p., e106448.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    FABP7 and HMGCS2 are novel protein markers for apocrine differentiation categorizing apocrine carcinoma of the breast

    Gromov, P., Espinoza, J. A., Talman, M., Honma, N., Kroman, N., Wielenga, V. T., Moreira, José & Gromova, I., 2014, In: P L o S One. 9, 11, 14 p., e112024.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Interactions of ion transporters and channels with cancer cell metabolism and the tumour microenvironment

    Andersen, Anne Poder, Moreira, José & Pedersen, Stine Helene Falsig, 2014, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 369, 1638, 11 p., 20130098.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Proteomic analysis of tissue samples in translational breast cancer research

    Gromov, P., Moreira, José & Gromova, I., 2014, In: Expert Review of Proteomics. 11, 3, p. 285-302 18 p.

    Research output: Contribution to journalReviewResearchpeer-review

  58. Published

    Purification and characterization of bioactive his6-tagged recombinant human tissue inhibitor of metalloproteinases-1 (TIMP-1) protein expressed at high yields in mammalian cells

    Jensen, L. V., Lademann, U. A., Andersen, E. V., Højrup, P., Thaysen-Andersen, M., Krogh, B. O., Viuff, B. M., Brünner, N., Stenvang, Jan & Moreira, José, 2014, In: Protein Expression and Purification. 101, p. 157-164 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Looking back, to go forward

    Moreira, José, 1 Jan 2014, In: Molecular Oncology. 8, 3, p. 445-446 2 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  60. 2015
  61. Published

    Acquisition of docetaxel resistance in breast cancer cells reveals upregulation of ABCB1 expression as a key mediator of resistance accompanied by discrete upregulation of other specific genes and pathways

    Hansen, S. N., Westergaard, David, Thomsen, M. B. H., Vistesen, M. V., Do, K. N., Fogh, L., Belling, K. G., Wang, J., Yang, H., Gupta, R., Ditzel, H. J., Moreira, José, Brünner, N., Stenvang, Jan & Rasmussen, A. S., 2015, In: Tumor Biology. 36, 6, p. 4327-4338 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    High level PHGDH expression in breast is predominantly associated with keratin 5-positive cell lineage independently of malignancy

    Gromova, I., Gromov, P., Honma, N., Kumar, S., Rimm, D., Talman, M. M., Wielenga, V. T. & Moreira, José, 2015, In: Molecular Oncology. 9, 8, p. 1636-1654 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Identification and characterization of a new TIMP-1 binding protein

    Moreira, José, Høeberg, M., Lademann, U. A., Viuff, B. M., Jensen, L. V., Stenvang, Jan, Nygård, S. B., Ørum-Madsen, M. S., Vistesen, M. V., Fuglsang, Anja Thoe, Liu, S. & Brünner, N., 2015, In: Cancer Research. 75, 9 suppl., 1 p., Abstract P5-07-08.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  64. Published

    Establishment and characterization of models of chemotherapy resistance in colorectal cancer: towards a predictive signature of chemoresistance

    Jensen, N. F., Stenvang, J., Beck, M. K., Hanáková, B., Belling, K. C., Do, K. N., Viuff, B. M., Nygård, S. B., Gupta, R., Rasmussen, M. H., Tarpgaard, L. S., Hansen, T. P., Budinská, E., Pfeiffer, P., Bosman, F., Tejpar, S., Roth, A., Delorenzi, M., Andersen, C. L., Rømer, M. U. K. & 2 others, Brünner, N. & Moreira, José, 24 Feb 2015, In: Molecular Oncology. 9, 6, p. 1169-1185 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Topoisomerase-1 gene copy aberrations are frequent in patients with breast cancer

    Kümler, I., Balslev, E., Poulsen, T. S., Nielsen, Signe Lykke, Nygård, S. B., Rømer, M. U., Christensen, I. J., Høgdall, E., Moreira, José, Nielsen, Dorte Lisbet, Brünner, N. & Stenvang, Jan, 8 Apr 2015, In: International Journal of Cancer. 137, 8, p. 2000-2006 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Drug transporters in breast cancer: response to anthracyclines and taxanes

    Kümler, I., Stenvang, Jan, Moreira, José, Brünner, N. & Nielsen, Dorte Lisbet, Sep 2015, In: Expert Review of Anticancer Therapy. 15, 9, p. 1075-1092 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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