Lasse Kristoffer Bak

Lasse Kristoffer Bak

Guest Researcher, Professor


  1. 2013
  2. Published

    Amino acid neurotransmitter synthesis and removal

    Schousboe, Arne, Bak, Lasse Kristoffer, Madsen, K. K. & Waagepetersen, Helle S., 2013, Neuroglia. Kettenman, H. & Ransom, B. R. (eds.). 3. ed. Oxford: Oxford University Press, p. 443-456 14 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  3. Published

    Astrocytic control of biosynthesis and turnover of the neurotransmitters glutamate and GABA

    Schousboe, Arne, Bak, Lasse Kristoffer & Waagepetersen, Helle S., 15 Aug 2013, In: Frontiers in Endocrinology. 4, 102.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2012
  5. Published

    Brain energy and ammonia metabolism

    Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 2012, Functional molecular imaging in hepatology. Bentham Science Publishers, Vol. 1. p. 129-144 16 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  6. Published

    Novel model of neuronal bioenergetics: postsynaptic utilization of glucose but not lactate correlates positively with Ca2+ signalling in cultured mouse glutamatergic neurons

    Bak, Lasse Kristoffer, Obel, L. L. F., Walls, Anne Byriel, Schousboe, Arne, Faek, S. A. A., Jajo, F. S. & Waagepetersen, Helle S., 2012, In: A S N Neuro. 4, 3, p. 151-160

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Valine but not leucine or isoleucine supports neurotransmitter glutamate synthesis during synaptic activity in cultured cerebellar neurons

    Bak, Lasse Kristoffer, Johansen, M. L., Schousboe, Arne & Waagepetersen, Helle S., 2012, In: Journal of Neuroscience Research. 90, 9, p. 1768-75 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Aspects of astrocyte energy metabolism, amino acid neurotransmitter homoeostasis and metabolic compartmentation

    Kreft, M., Bak, Lasse Kristoffer, Waagepetersen, Helle S. & Schousboe, Arne, 2012, In: A S N Neuro. 4, 3, p. 187 199 p.

    Research output: Contribution to journalReviewResearchpeer-review

  9. Published

    Primary cultures of astrocytes: their value in understanding astrocytes in health and disease

    Lange, S. C., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Schousboe, Arne & Norenberg, M. D., Nov 2012, In: Neurochemical Research. 37, 11, p. 2569-88 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Impairment of the organization of locomotor and exploratory behaviors in bile duct-ligated rats

    Leke, R., de Oliveira, D. L., Mussulini, B. H. M., Pereira, M. S., Kazlauckas, V., Mazzini, G., Hartmann, C. R., Silveira, T. R., Simonsen, M., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Keiding, S., Schousboe, Arne & Portela, L. V., 2012, In: P L o S One. 7, 5, p. e36322

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Brain glycogen: new perspectives on its metabolic function and regulation at the subcellular level

    Obel, L. L. F., Müller, M. S., Walls, Anne Byriel, Sickmann, H. M., Bak, Lasse Kristoffer, Waagepetersen, Helle S. & Schousboe, Arne, 2 Mar 2012, In: Frontiers in Neuroenergetics. 4, 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  12. Published
  13. 2011
  14. Published

    Brain energy and ammonia metabolism

    Bak, Lasse Kristoffer, Waagepetersen, Helle S. & Schousboe, Arne, 2011, Functional molecular imaging in hepatology. Bussum, The Netherlands: Bentham Science Publishers, p. 129-144

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  15. Published

    Glutamate and glutamine in brain disorders

    Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 2011, Neurochemical mechanisms in diseases. Blass, J. P. (ed.). New York: Springer Publishing Company, Vol. 1. p. 195-212 (Advances in Neurobiology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  16. Published

    Inhibition of glutamine synthesis induces glutamate dehydrogenase-dependent ammonia fixation into alanine in co-cultures of astrocytes and neurons

    Dadsetan, S., Bak, Lasse Kristoffer, Sørensen, M., Keiding, S., Vilstrup, H., Ott, P., Leke, R., Schousboe, Arne & Waagepetersen, Helle S., 1 Sep 2011, In: Neurochemistry International. 59, 4, p. 482-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Branched-chain amino acids increase arterial blood ammonia in spite of enhanced intrinsic muscle ammonia metabolism in patients with cirrhosis and healthy subjects

    Dam, G., Keiding, S., Munk, O. L., Ott, P., Buhl, M., Vilstrup, H., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Schousboe, Arne, Møller, N. & Sørensen, M., 1 Aug 2011, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 301, 2, p. G269-77

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Detoxification of ammonia in mouse cortical GABAergic cell cultures increases neuronal oxidative metabolism and reveals an emerging role for release of glucose-derived alanine

    Leke, R., Bak, Lasse Kristoffer, Anker, M., Melø, T. M., Sørensen, M., Keiding, S., Vilstrup, H., Ott, P., Portela, L. V., Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 1 Apr 2011, In: Neurotoxicity Research. 19, 3, p. 496-510 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Synthesis of neurotransmitter GABA via the neuronal tricarboxylic acid cycle is elevated in rats with liver cirrhosis consistent with a high GABAergic tone in chronic hepatic encephalopathy

    Leke, R., Bak, Lasse Kristoffer, Iversen, P., Sørensen, M., Keiding, S., Vilstrup, H., Ott, P., Portela, L. V., Schousboe, Arne & Waagepetersen, Helle S., 1 Jun 2011, In: Journal of Neurochemistry. 117, 5, p. 824-32 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    The Value of Example Solutions in Pharmacy Education: The role of seniority and gender.

    Sandelin, Albin Gustav, Hansen, H. R., Baldursdóttir, S. G., Kristensen, Anders Skov, Bak, Lasse Kristoffer, Christiansen, Frederik Voetmann & Selhuber-Unkel, C. J. M., 2011, In: Pharmacy Education. 11, 1, p. 32-37 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Neuron-glia interactions in glutamatergic neurotransmission: roles of oxidative and glycolytic adenosine triphosphate as energy source

    Schousboe, Arne, Sickmann, H. M., Bak, Lasse Kristoffer, Schousboe, I., Jajo, F. S., Faek, S. A. A. & Waagepetersen, Helle S., 1 Dec 2011, In: Journal of Neuroscience Research. 89, 12, p. 1926-34 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2010
  23. Published

    Planning and execution of a one-day PhD course employing the theory of didactical situations

    Bak, Lasse Kristoffer, 2010, Improving university science teaching and learning: pedagogical projects 2008. Voetmann Christiansen, F., Rump, C. & Degn, L. (eds.). Department of Science Education, University of Copenhagen, Vol. 1. p. 13-19 (Uden navn, Vol. 1).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  24. Published

    A functioning glycolysis is important for maintenance of glutamate transport in cultured astrocytes

    Schousboe, Arne, Sickmann, H. M., Bak, Lasse Kristoffer, Schousboe, I., Bouman, S. D. & Waagepetersen, Helle S., 2010, In: Journal of Neurochemistry. s1, p. 288-289

    Research output: Contribution to journalConference abstract in journalResearch

  25. Published

    Functional importance of the astrocytic glycogen-shunt and glycolysis for maintenance of an intact intra/extracellular glutamate gradient

    Schousboe, Arne, Sickmann, H. M., Walls, Anne Byriel, Bak, Lasse Kristoffer & Waagepetersen, Helle S., 2010, In: Neurotoxicity Research. 18, 1, p. 94-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. 2009
  27. Published

    Neuronal glucose but not lactate utilization is positively correlated with NMDA-induced neurotransmission and fluctuations in cytosolic Ca2+ levels

    Bak, Lasse Kristoffer, Walls, Anne Byriel, Schousboe, Arne, Ring, A., Sonnewald, U. & Waagepetersen, Helle S., 2009, In: Journal of Neurochemistry. 109, Suppl. 1, p. 87-93 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Metabolic fate of isoleucine in a rat model of hepatic encephalopathy and in cultured neural cells exposed to ammonia

    Bak, Lasse Kristoffer, Iversen, P., Sørensen, M., Keiding, S., Vilstrup, H., Ott, P., Waagepetersen, Helle S. & Schousboe, Arne, 2009, In: Metabolic Brain Disease. 24, 1, p. 135-145

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Low Cerebral Oxygen Consumption and Blood Flow in Patients With Cirrhosis and an Acute Episode of Hepatic Encephalopathy

    Iversen, P., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Vafaee, M. S., Borghammer, P., Mouridsen, K., Jensen, S. B., Vilstrup, H., Schousboe, Arne, Ott, P., Gjedde, Albert & Keiding, S., 2009, In: Gastroenterology. 136, 3, p. 863-871

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Reduced cerebral blood flow and oxygen consumption in cirrhosis patients with acute hepatic encephalopathy

    Keiding, S., Iversen, P., Sørensen, M., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Gjedde, A., Schousboe, Arne & Vilstrup, H., 2009, In: Journal of Neurochemistry. s1, p. 269-270

    Research output: Contribution to journalConference abstract in journalResearch

ID: 1303653