Lasse Kristoffer Bak
Guest Researcher, Professor
Molecular and Cellular Pharmacology
Jagtvej 160
2100 København Ø
TG IV
Jagtvej 160
2100 København Ø
- Published
Metabolism of [U-13C]glutamine and [U-13C]glutamate in isolated rat brain mitochondria suggests functional phosphate-activated glutaminase activity in matrix
Bak, Lasse Kristoffer, Zieminska, E., Waagepetersen, Helle S., Schousboe, Arne & Albrecht, J., 2008, In: Neurochemical Research. 33, 2, p. 273-278Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Misconceptions regarding basic thermodynamics and enzyme kinetics have led to erroneous conclusions regarding the metabolic importance of lactate dehydrogenase isoenzyme expression
Bak, Lasse Kristoffer & Schousboe, Arne, Nov 2017, In: Journal of Neuroscience Research. 95, 11, p. 2098-2102 5 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Neuron-glia interactions in glutamatergic neurotransmission: roles of oxidative and glycolytic adenosine triphosphate as energy source
Schousboe, Arne, Sickmann, H. M., Bak, Lasse Kristoffer, Schousboe, I., Jajo, F. S., Faek, S. A. A. & Waagepetersen, Helle S., 1 Dec 2011, In: Journal of Neuroscience Research. 89, 12, p. 1926-34 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuronal Cell Death Induced by Mechanical Percussion Trauma in Cultured Neurons is not Preceded by Alterations in Glucose, Lactate and Glutamine Metabolism
Jayakumar, A. R., Bak, Lasse Kristoffer, Rama Rao, K. V., Waagepetersen, Helle S., Schousboe, Arne & Norenberg, M. D., Feb 2016, In: Neurochemical Research. 41, 1, p. 307-15 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuronal glucose but not lactate utilization is positively correlated with NMDA-induced neurotransmission and fluctuations in cytosolic Ca2+ levels
Bak, Lasse Kristoffer, Walls, Anne Byriel, Schousboe, Arne, Ring, A., Sonnewald, U. & Waagepetersen, Helle S., 2009, In: Journal of Neurochemistry. 109, Suppl. 1, p. 87-93 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel model of neuronal bioenergetics: postsynaptic utilization of glucose but not lactate correlates positively with Ca2+ signalling in cultured mouse glutamatergic neurons
Bak, Lasse Kristoffer, Obel, L. L. F., Walls, Anne Byriel, Schousboe, Arne, Faek, S. A. A., Jajo, F. S. & Waagepetersen, Helle S., 2012, In: A S N Neuro. 4, 3, p. 151-160Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxidative metabolism of astrocytes is not reduced in hepatic encephalopathy: a PET study with [(11)C]acetate in humans
Iversen, P., Mouridsen, K., Hansen, M. B., Jensen, S. B., Sørensen, M., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Schousboe, Arne, Ott, P., Vilstrup, H., Keiding, S. & Gjedde, Albert, 2014, In: Frontiers in Neuroscience. 8, p. 353Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PARK2 Mutation Causes Metabolic Disturbances and Impaired Survival of Human iPSC-Derived Neurons
Bogetofte, H., Jensen, P., Ryding, M., Schmidt, S. I., Okarmus, J., Ritter, L., Worm, C. S., Hohnholt, M. C., Azevedo, C., Roybon, L., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Ryan, B. J., Wade-Martins, R., Larsen, M. R. & Meyer, M., 2019, In: Frontiers in Cellular Neuroscience. 13, 14 p., 297.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patient iPSC-derived neurons for disease modeling of frontotemporal dementia with mutation in CHMP2B
Zhang, Y., Schmid, B., Qas Younan, N. K., Rasmussen, M. A., Garcia, B. I. A., Agger, M., Callø, K., Stummann, T. C., Larsen, H. M., Nielsen, T. T., Huang, J., Xu, F., Liu, X., Bolund, L., Meyer, M., Bak, L. K., Waagepetersen, H. S., Luo, Y., Nielsen, J. E., Consortium, T. FRA. & 4 others, , 2017, In: Stem Cell Reports. 8, 3, p. 648-658Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacological inhibition of mitochondrial soluble adenylyl cyclase in astrocytes causes activation of AMP-activated protein kinase and induces breakdown of glycogen
Jakobsen, Emil, Andersen, Jens Velde, Christensen, S. K., Siamka, O., Larsen, M. R., Waagepetersen, Helle S., Aldana, Blanca & Bak, Lasse Kristoffer, 2021, In: Glia. 69, 12, p. 2828-2844 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1303653
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Patient iPSC-derived neurons for disease modeling of frontotemporal dementia with mutation in CHMP2B
Research output: Contribution to journal › Journal article › Research › peer-review
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321
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Compartmentalised signalling-metabolism coupling in brain cells - putative drug targets for neurological diseases?
Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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195
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Inhibition of soluble adenylyl cyclase (SAC) causes a robust increase in glycolysis in cultured astrocytes
Research output: Contribution to conference › Poster › Research
Published