Matthias Manfred Herth
Professor
Medicinal Chemistry
Jagtvej 162
2100 København Ø
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Repeated low doses of psilocybin increase resilience to stress, lower compulsive actions, and strengthen cortical connections to the paraventricular thalamic nucleus in rats
Kiilerich, K. F., Lorenz, J., Scharff, M. B., Speth, N., Brandt, T. G., Czurylo, J., Xiong, M., Jessen, N. S., Casado-Sainz, A., Shalgunov, Vladimir, Kjærby, Celia, Satała, G., Bojarski, A. J., Jensen, Anders A., Herth, Matthias Manfred, Cumming, P., Overgaard, A. & Palner, M., 2023, In: Molecular Psychiatry. 28, 9, p. 3829-3841Research output: Contribution to journal › Journal article › Research › peer-review
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The Center for Integrated Molecular Brain Imaging (Cimbi) database
Knudsen, G. M., Jensen, P. S., Erritzoe, D., Baaré, W. F. C., Ettrup, A., Fisher, P. M., Gillings, N., Hansen, H. D., Hansen, L. K., Hasselbalch, S. G., Henningsson, S., Herth, M. M., Holst, K. K., Iversen, P., Kessing, L. V., Macoveanu, J., Madsen, K. S., Mortensen, E. L., Nielsen, F. Å., Paulson, O. B. & 6 others, , 17 Apr 2015, In: NeuroImage. 124 , Part B, p. 1213-19 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Alpha-Synuclein PET tracer development-an overview about current efforts
Korat, Š., Bidesi, N. S. R., Bonanno, F., Di Nanni, A., Hoàng, A. N. N., Herfert, K., Maurer, A., Battisti, Umberto Maria, Bowden, G. D., Thonon, D., Vugts, D., Windhorst, A. D. & Herth, Matthias Manfred, 2021, In: Pharmaceuticals. 14, 9, 45 p., 847.Research output: Contribution to journal › Review › Research › peer-review
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Practical considerations for navigating the regulatory landscape of non-clinical studies for clinical translation of radiopharmaceuticals
Korde, A., Mikolajczak, R., Kolenc, P., Bouziotis, P., Westin, H., Lauritzen, M., Koole, M., Herth, Matthias Manfred, Bardiès, M., Martins, A. F., Paulo, A., Lyashchenko, S. K., Todde, S., Nag, S., Lamprou, E., Abrunhosa, A., Giammarile, F. & Decristoforo, C., 2022, In: EJNMMI Radiopharmacy and Chemistry. 7, 1, 18.Research output: Contribution to journal › Review › Research › peer-review
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Structural combination of established 5-HT(2A) receptor ligands: new aspects of the binding mode
Kramer, V., Herth, Matthias Manfred, Santini, M. A., Palner, M., Knudsen, Gitte Moos & Rösch, F., 1 Oct 2010, In: Chemical Biology & Drug Design (Online). 76, 4, p. 361-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of the serotonin 2A receptor selective PET tracer (R)-[18F]MH.MZ in the human brain
Kramer, V., Dyssegaard, A., Flores, J., Soza-Ried, C., Rösch, F., Knudsen, Gitte Moos, Amaral, H. & Herth, Matthias Manfred, 2020, In: European Journal of Nuclear Medicine and Molecular Imaging. 47, p. 355-365Research output: Contribution to journal › Journal article › Research › peer-review
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In vivo imaging in drug discovery
Kristensen, Jesper Langgaard & Herth, Matthias Manfred, 19 Aug 2016, Textbook of Drug Design and Discovery, Fifth Edition. CRC Press, p. 19-135 117 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Textbook of Drug Design and Discovery: In vivo imaging in drug discovery
Kristensen, Jesper Langgaard & Herth, Matthias Manfred, 2017, Textbook of Drug Design and Discovery. Fifth edition ed. CRC PressResearch output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Novel, Versatile Three-Step Synthesis of 1,2,3,4,10,10a-Hexahydropyrazino[1,2-a]indoles by Intramolecular Carbene-Mediated C-H Insertion
Krogsgaard-Larsen, N., Begtrup, M., Herth, Matthias Manfred & Kehler, J., Dec 2010, In: Synthesis. 24, p. 4287-4299Research output: Contribution to journal › Journal article › Research › peer-review
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Radiosynthesis and preclinical evaluation of [11 C]Cimbi-701 - Towards the imaging of cerebral 5-HT7 receptors
L 'Estrade, E. T., Shalgunov, Vladimir, Edgar, F. G., Strebl-Bantillo, M. G., Xiong, M., Crestey, F., Neelamegam, R., Dyssegaard, A., Lehel, S., Erlandsson, M., Ohlsson, T., Hooker, J. M., Knudsen, Gitte Moos, Herth, Matthias Manfred & Hansen, H. D., 2020, In: Journal of Labelled Compounds and Radiopharmaceuticals. 63, p. 46-55Research output: Contribution to journal › Journal article › Research › peer-review
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Towards selective CNS PET Imaging of the 5-HT7 Receptor System: Past, Present and Future
L'Estrade, E. T., Erlandsson, M., Edgar, F. G., Ohlsson, T., Knudsen, Gitte Moos & Herth, Matthias Manfred, 2020, In: Neuropharmacology. 172, 107830.Research output: Contribution to journal › Review › Research › peer-review
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Synthesis and Pharmacological Evaluation of [C-11]4-Methoxy-N-[2-(thiophen-2-yl) imidazo[1,2-a] pyridin-3-yl]benzamide as a Brain Penetrant PET Ligand Selective for the delta-Subunit-Containing gamma-Aminobutyric Acid Type A Receptors
L'Estrade, E. T., Hansen, H. D., Falk-Petersen, C., Haugaard, A., Griem-Krey, Nane, Jung, S., Lueddens, H., Schirmeister, T., Erlandsson, M., Ohlsson, T., Knudsen, Gitte Moos, Herth, Matthias Manfred, Wellendorph, Petrine & Frølund, Bente, May 2019, In: ACS Omega. 4, 5, p. 8846-8851Research output: Contribution to journal › Journal article › Research › peer-review
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PET radiotracer translation from rats to higher species, using an increased-throughput in vivo evaluation strategy
L'Estrade, E. T., Xiong, M., Petersen, I., Shalgunov, Vladimir, Edgar, F. G., Hansen, H., Erlandsson, M., Ohlsson, T., Knudsen, Gitte Moos, Palner, M. & Herth, Matthias Manfred, May 2019, p. S389-S390.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Design, synthesis, radiolabeling and in vivo evaluation of potential positron emission tomography (PET) radioligands for brain imaging of the 5-HT7 receptor
Lacivita, E., Niso, M., Hansen, H. D., Di Pilato, P., Herth, Matthias Manfred, Lehel, S., Ettrup, A., Montenegro, L., Perrone, R., Berardi, F., Colabufo, N. A., Leopoldo, M. & Knudsen, G. M., 1 Mar 2014, In: Bioorganic & Medicinal Chemistry. 22, 5, p. 1736-1750 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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High-throughput rat brain PET imaging and automatic spatial normalization of the dopamine D2/3 receptor ligand [F-18]fallypride
Lange, D., Tejada, I. M., Xiong, M., Hillebrand, B., Noergaard, M., Baerentzen, S., Shalgunov, Vladimir, Herth, Matthias Manfred, Svarer, C. & Palner, M., 2019, In: Journal of Cerebral Blood Flow and Metabolism. 39, p. 588-589 2 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Selective O-[C-11]methylation of 1-(3-hydroxyphenyl)piperazine
Lehel, S., Herth, Matthias Manfred, Andersen, V. L., Gillings, N. & Madsen, J., 15 May 2015, In: Journal of Labelled Compounds and Radiopharmaceuticals. 58, p. S334-S334Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Development and evaluation of an 18F-labeled nanobody to target SARS-CoV-2's spike protein
Lopes van den Broek, S., García-Vázquez, R., Andersen, Ida Vang, Valenzuela-Nieto, G., Shalgunov, Vladimir, Battisti, Umberto Maria, Schwefel, D., Modhiran, N., Kramer, V., Cheuquemilla, Y., Jara, R., Salinas-Varas, C., Amarilla, A. A., Watterson, D., Rojas-Fernandez, A. & Herth, Matthias Manfred, 2022, In: Frontiers in Nuclear Medicine. 2, 1033697.Research output: Contribution to journal › Journal article › Research › peer-review
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Pretargeted Imaging beyond the Blood–Brain Barrier: Utopia or Feasible?
Lopes van den Broek, S., Shalgunov, Vladimir, García Vázquez, R., Beschorner, Natalie, Bidesi, N. S. R., Nedergaard, Maiken, Knudsen, Gitte Moos, Sehlin, D., Syvänen, S. & Herth, Matthias Manfred, 2022, In: Pharmaceuticals. 15, 10, 13 p., 1191.Research output: Contribution to journal › Journal article › Research › peer-review
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The Alzheimer's disease 5xFAD mouse model is best suited to investigate pretargeted imaging approaches beyond the blood-brain barrier
Lopes van den Broek, S. I., Sehlin, D., Andersen, Jens Velde, Aldana, Blanca, Beschorner, Natalie, Nedergaard, Maiken, Knudsen, Gitte Moos, Syvanen, S. & Herth, Matthias Manfred, 2023, In: Frontiers in Nuclear Medicine. 2, 7 p., 1001722.Research output: Contribution to journal › Journal article › Research › peer-review
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Radiolabeling and in vivo evaluation of [11C]AGH-44: a potential lead structure to develop a positron emission tomography radioligand for the 5-HT7 receptor
L’Estrade, E. T., Petersen, I. N., Xiong, M., Hogendorf, A. S., Hogendorf, A., Kristensen, Jesper Langgaard, Kjær, Andreas, Bojarski, A. J., Erlandsson, M., Ohlsson, T., Knudsen, Gitte Moos & Herth, Matthias Manfred, 1 Nov 2019, In: Journal of Radioanalytical and Nuclear Chemistry. 322, 2, p. 847-851 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A facile synthesis of precursor for the σ-1 receptor PET radioligand [18F]FTC-146 and its radiofluorination
Marešová, A., Jurášek, M., Drašar, P. B., Dolenský, B., Prokudina, E. A., Shalgunov, Vladimir, Herth, Matthias Manfred, Cumming, P. & Popkov, A., 2024, In: Journal of Labelled Compounds and Radiopharmaceuticals. 67, 2, p. 59-66Research output: Contribution to journal › Journal article › Research › peer-review
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Three weeks of daily exposure to bright light does not alter striatal serotonin transporter binding in healthy Scandinavians
Mc Mahon, B., Andersen, A. S., Feng, L., Madsen, M. K., Lehel, S., Herth, Matthias Manfred, Iversen, P., Hasholt, Lis Frydenreich & Knudsen, G. M., Aug 2012, In: Journal of Cerebral Blood Flow and Metabolism. 32, p. S79-S80Research output: Contribution to journal › Journal article › Research › peer-review
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A nanobody recognizes a unique conserved epitope and potently neutralizes SARS-CoV-2 omicron variants
Modhiran, N., Lauer, S. M., Amarilla, A. A., Hewins, P., Lopes van den Broek, S. I., Low, Y. S., Thakur, N., Liang, B., Nieto, G. V., Jung, J., Paramitha, D., Isaacs, A., Sng, J. D. J., Song, D., Jørgensen, J. T., Cheuquemilla, Y., Bürger, J., Andersen, I. V., Himelreichs, J., Jara, R. & 18 others, , 2023, In: iScience. 26, 7, 26 p., 107085.Research output: Contribution to journal › Journal article › Research › peer-review
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Synthesis, radiofluorination and first evaluation of (+/-)-[F-18]MDL 100907 as serotonin 5-HT2A receptor antagonist for PET
Muehlhausen, U., Ermert, J., Herth, Matthias Manfred & Coenen, H. H., 2009, In: Journal of Labelled Compounds and Radiopharmaceuticals. 52, 1-2, p. 6-12Research output: Contribution to journal › Journal article › Research › peer-review
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Synthesis and in vivo evaluation of [11C]tucatinib for HER2-targeted PET imaging
Müller, Marius, Shalgunov, Vladimir, Hvass, Lars, Jørgensen, Jesper Tranekjær, Kramer, V., Staudt, Markus, Battisti, Umberto Maria, Kjær, Andreas & Herth, Matthias Manfred, 2023, In: Bioorganic and Medicinal Chemistry Letters. 80, 5 p., 129088.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 33147568
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SPECT imaging of the glymphatic pathway with In-111-labeled ovalbumin in the rat brain
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Convenient access to F-18-labeled amines through the Staudinger reduction
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369
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Pretargeting in nuclear imaging and radionuclide therapy: Improving efficacy of theranostics and nanomedicines
Research output: Contribution to journal › Journal article › Research › peer-review
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