Matthias Manfred Herth

Matthias Manfred Herth

Professor


  1. Published

    Repeated low doses of psilocybin increase resilience to stress, lower compulsive actions, and strengthen cortical connections to the paraventricular thalamic nucleus in rats

    Kiilerich, K. F., Lorenz, J., Scharff, M. B., Speth, N., Brandt, T. G., Czurylo, J., Xiong, M., Jessen, N. S., Casado-Sainz, A., Shalgunov, Vladimir, Kjærby, Celia, Satała, G., Bojarski, A. J., Jensen, Anders A., Herth, Matthias Manfred, Cumming, P., Overgaard, A. & Palner, M., 2023, In: Molecular Psychiatry. 28, 9, p. 3829-3841

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    The Center for Integrated Molecular Brain Imaging (Cimbi) database

    Knudsen, G. M., Jensen, P. S., Erritzoe, D., Baaré, W. F. C., Ettrup, A., Fisher, P. M., Gillings, N., Hansen, H. D., Hansen, L. K., Hasselbalch, S. G., Henningsson, S., Herth, M. M., Holst, K. K., Iversen, P., Kessing, L. V., Macoveanu, J., Madsen, K. S., Mortensen, E. L., Nielsen, F. Å., Paulson, O. B. & 6 others, Siebner, Hartwig Roman, Stenbæk, D. S., Svarer, C., Jernigan, T. L., Strother, S. C. & Frøkjær, Vibe Gedsø, 17 Apr 2015, In: NeuroImage. 124 , Part B, p. 1213-19 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Alpha-Synuclein PET tracer development-an overview about current efforts

    Korat, Š., Bidesi, N. S. R., Bonanno, F., Di Nanni, A., Hoàng, A. N. N., Herfert, K., Maurer, A., Battisti, Umberto Maria, Bowden, G. D., Thonon, D., Vugts, D., Windhorst, A. D. & Herth, Matthias Manfred, 2021, In: Pharmaceuticals. 14, 9, 45 p., 847.

    Research output: Contribution to journalReviewResearchpeer-review

  4. Published

    Practical considerations for navigating the regulatory landscape of non-clinical studies for clinical translation of radiopharmaceuticals

    Korde, A., Mikolajczak, R., Kolenc, P., Bouziotis, P., Westin, H., Lauritzen, M., Koole, M., Herth, Matthias Manfred, Bardiès, M., Martins, A. F., Paulo, A., Lyashchenko, S. K., Todde, S., Nag, S., Lamprou, E., Abrunhosa, A., Giammarile, F. & Decristoforo, C., 2022, In: EJNMMI Radiopharmacy and Chemistry. 7, 1, 18.

    Research output: Contribution to journalReviewResearchpeer-review

  5. Published

    Structural combination of established 5-HT(2A) receptor ligands: new aspects of the binding mode

    Kramer, V., Herth, Matthias Manfred, Santini, M. A., Palner, M., Knudsen, Gitte Moos & Rösch, F., 1 Oct 2010, In: Chemical Biology & Drug Design (Online). 76, 4, p. 361-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Characterization of the serotonin 2A receptor selective PET tracer (R)-[18F]MH.MZ in the human brain

    Kramer, V., Dyssegaard, A., Flores, J., Soza-Ried, C., Rösch, F., Knudsen, Gitte Moos, Amaral, H. & Herth, Matthias Manfred, 2020, In: European Journal of Nuclear Medicine and Molecular Imaging. 47, p. 355-365

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    In vivo imaging in drug discovery

    Kristensen, Jesper Langgaard & Herth, Matthias Manfred, 19 Aug 2016, Textbook of Drug Design and Discovery, Fifth Edition. CRC Press, p. 19-135 117 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  8. Published

    Textbook of Drug Design and Discovery: In vivo imaging in drug discovery

    Kristensen, Jesper Langgaard & Herth, Matthias Manfred, 2017, Textbook of Drug Design and Discovery. Fifth edition ed. CRC Press

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  9. Published

    Novel, Versatile Three-Step Synthesis of 1,2,3,4,10,10a-Hexahydropyrazino[1,2-a]indoles by Intramolecular Carbene-Mediated C-H Insertion

    Krogsgaard-Larsen, N., Begtrup, M., Herth, Matthias Manfred & Kehler, J., Dec 2010, In: Synthesis. 24, p. 4287-4299

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Radiosynthesis and preclinical evaluation of [11 C]Cimbi-701 - Towards the imaging of cerebral 5-HT7 receptors

    L 'Estrade, E. T., Shalgunov, Vladimir, Edgar, F. G., Strebl-Bantillo, M. G., Xiong, M., Crestey, F., Neelamegam, R., Dyssegaard, A., Lehel, S., Erlandsson, M., Ohlsson, T., Hooker, J. M., Knudsen, Gitte Moos, Herth, Matthias Manfred & Hansen, H. D., 2020, In: Journal of Labelled Compounds and Radiopharmaceuticals. 63, p. 46-55

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Towards selective CNS PET Imaging of the 5-HT7 Receptor System: Past, Present and Future

    L'Estrade, E. T., Erlandsson, M., Edgar, F. G., Ohlsson, T., Knudsen, Gitte Moos & Herth, Matthias Manfred, 2020, In: Neuropharmacology. 172, 107830.

    Research output: Contribution to journalReviewResearchpeer-review

  12. Published

    Synthesis and Pharmacological Evaluation of [C-11]4-Methoxy-N-[2-(thiophen-2-yl) imidazo[1,2-a] pyridin-3-yl]benzamide as a Brain Penetrant PET Ligand Selective for the delta-Subunit-Containing gamma-Aminobutyric Acid Type A Receptors

    L'Estrade, E. T., Hansen, H. D., Falk-Petersen, C., Haugaard, A., Griem-Krey, Nane, Jung, S., Lueddens, H., Schirmeister, T., Erlandsson, M., Ohlsson, T., Knudsen, Gitte Moos, Herth, Matthias Manfred, Wellendorph, Petrine & Frølund, Bente, May 2019, In: ACS Omega. 4, 5, p. 8846-8851

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    PET radiotracer translation from rats to higher species, using an increased-throughput in vivo evaluation strategy

    L'Estrade, E. T., Xiong, M., Petersen, I., Shalgunov, Vladimir, Edgar, F. G., Hansen, H., Erlandsson, M., Ohlsson, T., Knudsen, Gitte Moos, Palner, M. & Herth, Matthias Manfred, May 2019, p. S389-S390.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  14. Published

    Design, synthesis, radiolabeling and in vivo evaluation of potential positron emission tomography (PET) radioligands for brain imaging of the 5-HT7 receptor

    Lacivita, E., Niso, M., Hansen, H. D., Di Pilato, P., Herth, Matthias Manfred, Lehel, S., Ettrup, A., Montenegro, L., Perrone, R., Berardi, F., Colabufo, N. A., Leopoldo, M. & Knudsen, G. M., 1 Mar 2014, In: Bioorganic & Medicinal Chemistry. 22, 5, p. 1736-1750 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    High-throughput rat brain PET imaging and automatic spatial normalization of the dopamine D2/3 receptor ligand [F-18]fallypride

    Lange, D., Tejada, I. M., Xiong, M., Hillebrand, B., Noergaard, M., Baerentzen, S., Shalgunov, Vladimir, Herth, Matthias Manfred, Svarer, C. & Palner, M., 2019, In: Journal of Cerebral Blood Flow and Metabolism. 39, p. 588-589 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  16. Published

    Selective O-[C-11]methylation of 1-(3-hydroxyphenyl)piperazine

    Lehel, S., Herth, Matthias Manfred, Andersen, V. L., Gillings, N. & Madsen, J., 15 May 2015, In: Journal of Labelled Compounds and Radiopharmaceuticals. 58, p. S334-S334

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  17. Published

    Development and evaluation of an 18F-labeled nanobody to target SARS-CoV-2's spike protein

    Lopes van den Broek, S., García-Vázquez, R., Andersen, Ida Vang, Valenzuela-Nieto, G., Shalgunov, Vladimir, Battisti, Umberto Maria, Schwefel, D., Modhiran, N., Kramer, V., Cheuquemilla, Y., Jara, R., Salinas-Varas, C., Amarilla, A. A., Watterson, D., Rojas-Fernandez, A. & Herth, Matthias Manfred, 2022, In: Frontiers in Nuclear Medicine. 2, 1033697.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Pretargeted Imaging beyond the Blood–Brain Barrier: Utopia or Feasible?

    Lopes van den Broek, S., Shalgunov, Vladimir, García Vázquez, R., Beschorner, Natalie, Bidesi, N. S. R., Nedergaard, Maiken, Knudsen, Gitte Moos, Sehlin, D., Syvänen, S. & Herth, Matthias Manfred, 2022, In: Pharmaceuticals. 15, 10, 13 p., 1191.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The Alzheimer's disease 5xFAD mouse model is best suited to investigate pretargeted imaging approaches beyond the blood-brain barrier

    Lopes van den Broek, S. I., Sehlin, D., Andersen, Jens Velde, Aldana, Blanca, Beschorner, Natalie, Nedergaard, Maiken, Knudsen, Gitte Moos, Syvanen, S. & Herth, Matthias Manfred, 2023, In: Frontiers in Nuclear Medicine. 2, 7 p., 1001722.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Radiolabeling and in vivo evaluation of [11C]AGH-44: a potential lead structure to develop a positron emission tomography radioligand for the 5-HT7 receptor

    L’Estrade, E. T., Petersen, I. N., Xiong, M., Hogendorf, A. S., Hogendorf, A., Kristensen, Jesper Langgaard, Kjær, Andreas, Bojarski, A. J., Erlandsson, M., Ohlsson, T., Knudsen, Gitte Moos & Herth, Matthias Manfred, 1 Nov 2019, In: Journal of Radioanalytical and Nuclear Chemistry. 322, 2, p. 847-851 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    A facile synthesis of precursor for the σ-1 receptor PET radioligand [18F]FTC-146 and its radiofluorination

    Marešová, A., Jurášek, M., Drašar, P. B., Dolenský, B., Prokudina, E. A., Shalgunov, Vladimir, Herth, Matthias Manfred, Cumming, P. & Popkov, A., 2024, In: Journal of Labelled Compounds and Radiopharmaceuticals. 67, 2, p. 59-66

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Three weeks of daily exposure to bright light does not alter striatal serotonin transporter binding in healthy Scandinavians

    Mc Mahon, B., Andersen, A. S., Feng, L., Madsen, M. K., Lehel, S., Herth, Matthias Manfred, Iversen, P., Hasholt, Lis Frydenreich & Knudsen, G. M., Aug 2012, In: Journal of Cerebral Blood Flow and Metabolism. 32, p. S79-S80

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    A nanobody recognizes a unique conserved epitope and potently neutralizes SARS-CoV-2 omicron variants

    Modhiran, N., Lauer, S. M., Amarilla, A. A., Hewins, P., Lopes van den Broek, S. I., Low, Y. S., Thakur, N., Liang, B., Nieto, G. V., Jung, J., Paramitha, D., Isaacs, A., Sng, J. D. J., Song, D., Jørgensen, J. T., Cheuquemilla, Y., Bürger, J., Andersen, I. V., Himelreichs, J., Jara, R. & 18 others, MacLoughlin, R., Miranda-Chacon, Z., Chana-Cuevas, P., Kramer, V., Spahn, C., Mielke, T., Khromykh, A. A., Munro, T., Jones, M. L., Young, P. R., Chappell, K., Bailey, D., Kjær, Andreas, Herth, Matthias Manfred, Jurado, K. A., Schwefel, D., Rojas-Fernandez, A. & Watterson, D., 2023, In: iScience. 26, 7, 26 p., 107085.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Synthesis, radiofluorination and first evaluation of (+/-)-[F-18]MDL 100907 as serotonin 5-HT2A receptor antagonist for PET

    Muehlhausen, U., Ermert, J., Herth, Matthias Manfred & Coenen, H. H., 2009, In: Journal of Labelled Compounds and Radiopharmaceuticals. 52, 1-2, p. 6-12

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Synthesis and in vivo evaluation of [11C]tucatinib for HER2-targeted PET imaging

    Müller, Marius, Shalgunov, Vladimir, Hvass, Lars, Jørgensen, Jesper Tranekjær, Kramer, V., Staudt, Markus, Battisti, Umberto Maria, Kjær, Andreas & Herth, Matthias Manfred, 2023, In: Bioorganic and Medicinal Chemistry Letters. 80, 5 p., 129088.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 33147568