Matthias Manfred Herth

Matthias Manfred Herth

Professor


  1. 2017
  2. Published

    Nucleophilic 18F-Labeling of Spirocyclic Iodonium Ylide or Boronic Pinacol Ester Precursors - Advantages and Disadvantages

    Petersen, I. N., Kristensen, Jesper Langgaard & Herth, Matthias Manfred, 18 Jan 2017, In: European Journal of Organic Chemistry. 2017, 3, p. 453-458 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Radiosynthesis and Evaluation of [(11)C]3-Hydroxycyclopent-1-enecarboxylic Acid as Potential PET Ligand for the High-Affinity γ-Hydroxybutyric Acid Binding Sites

    Jensen, C. H., Hansen, H. D., Bay, T., Vogensen, S. B., Lehel, S., Thiesen, L., Bundgaard, C., Clausen, Rasmus Prætorius, Knudsen, Gitte Moos, Herth, Matthias Manfred, Wellendorph, Petrine & Frølund, Bente, 18 Jan 2017, In: A C S Chemical Neuroscience. 8, 1, p. 22-27 6 p.

    Research output: Contribution to journalLetterResearchpeer-review

  4. Published

    Development of a simple proton nuclear magnetic resonance-based procedure to estimate the approximate distribution coefficient at physiological pH (logD7.4): Evaluation and comparison to existing practices

    Stéen, E. J. L., Nyberg, N., Lehel, S., Andersen, V. L., Di Pilato, P., Knudsen, Gitte Moos, Kristensen, Jesper Langgaard & Herth, Matthias Manfred, 15 Jan 2017, In: Bioorganic & Medicinal Chemistry Letters. 27, 2, p. 319-322 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Textbook of Drug Design and Discovery: In vivo imaging in drug discovery

    Kristensen, Jesper Langgaard & Herth, Matthias Manfred, 2017, Textbook of Drug Design and Discovery. Fifth edition ed. CRC Press

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  6. 2016
  7. Published

    In vivo imaging in drug discovery

    Kristensen, Jesper Langgaard & Herth, Matthias Manfred, 19 Aug 2016, Textbook of Drug Design and Discovery, Fifth Edition. CRC Press, p. 19-135 117 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  8. Published

    Synthesis and evaluation of 18F-labeled 5-HT2A receptor agonists as PET ligands

    Herth, Matthias Manfred, Petersen, I. N., Hansen, H. D., Hansen, M., Ettrup, A., Jensen, Anders A., Lehel, S., Dyssegaard, A., Gillings, N., Knudsen, G. M. & Kristensen, Jesper Langgaard, 19 Apr 2016, In: Nuclear Medicine and Biology. 43, 8, p. 455-462 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Convergent [18]F-labeling and evaluation of N-benzyl-phenethylamines as 5-HT2A receptor PET ligands

    Petersen, I. N., Villadsen, J., Hansen, H. D., Jensen, Anders A., Lehel, S., Gillings, N., Herth, Matthias Manfred, Knudsen, G. M. & Kristensen, Jesper Langgaard, 2016, In: Bioorganic & Medicinal Chemistry. 24, p. 5353-5356 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    In Vivo Radionuclide Generators for Diagnostics and Therapy

    Edem, P. E., Fonslet, J., Kjær, Andreas, Herth, Matthias Manfred & Severin, G., 2016, In: Bioinorganic Chemistry and Applications. 2016, p. 1-9 9 p., 6148357.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2015
  12. Published

    Current radiosynthesis strategies for 5-HT2A receptor PET tracers

    Herth, Matthias Manfred & Knudsen, G. M., 15 Jun 2015, In: Journal of Labelled Compounds and Radiopharmaceuticals. 58, 7, p. 265-73 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    An Improved Radiolabelling Strategy for the 5-HT2A Agonist, [C-11]Cimbi-36

    Gillings, N., Lehel, S., Herth, Matthias Manfred, Leth-Petersen, S., Madsen, J., Gabel-Jensen, C. & Kristensen, Jesper Langgaard, 15 May 2015, In: Journal of Labelled Compounds and Radiopharmaceuticals. 58, p. S296-S296 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  14. Published

    Selective O-[C-11]methylation of 1-(3-hydroxyphenyl)piperazine

    Lehel, S., Herth, Matthias Manfred, Andersen, V. L., Gillings, N. & Madsen, J., 15 May 2015, In: Journal of Labelled Compounds and Radiopharmaceuticals. 58, p. S334-S334

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  15. Published

    Labeling and preliminary in vivo evaluation of the 5-HT7 receptor selective agonist [(11)C]E-55888

    Hansen, H. D., Andersen, V. L., Lehel, S., Magnussen, J. H., Dyssegaard, A., Stroth, N., Kristensen, Jesper Langgaard, Knudsen, G. M. & Herth, Matthias Manfred, 1 May 2015, In: Bioorganic & Medicinal Chemistry Letters. 25, 9, p. 1901-4 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    The Center for Integrated Molecular Brain Imaging (Cimbi) database

    Knudsen, G. M., Jensen, P. S., Erritzoe, D., Baaré, W. F. C., Ettrup, A., Fisher, P. M., Gillings, N., Hansen, H. D., Hansen, L. K., Hasselbalch, S. G., Henningsson, S., Herth, M. M., Holst, K. K., Iversen, P., Kessing, L. V., Macoveanu, J., Madsen, K. S., Mortensen, E. L., Nielsen, F. Å., Paulson, O. B. & 6 others, Siebner, Hartwig Roman, Stenbæk, D. S., Svarer, C., Jernigan, T. L., Strother, S. C. & Frøkjær, Vibe Gedsø, 17 Apr 2015, In: NeuroImage. 124 , Part B, p. 1213-19 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Evaluation of 3-Ethyl-3-(phenylpiperazinylbutyl)oxindoles as PET Ligands for the Serotonin 5-HT7 Receptor: Synthesis, Pharmacology, Radiolabeling, and in Vivo Brain Imaging in Pigs

    Herth, Matthias Manfred, Andersen, V. L., Hansen, H. D., Stroth, N., Volk, B., Lehel, S., Dyssegaard, A., Ettrup, A., Svenningsson, P., Knudsen, G. M. & Kristensen, Jesper Langgaard, 13 Apr 2015, In: Journal of Medicinal Chemistry. 58, 8, p. 3631–3636 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    (11)C-labeling and preliminary evaluation of pimavanserin as a 5-HT2A receptor PET-radioligand

    Andersen, V. L., Hansen, H. D., Herth, Matthias Manfred, Dyssegaard, A., Knudsen, G. M. & Kristensen, Jesper Langgaard, 20 Jan 2015, In: Bioorganic & Medicinal Chemistry Letters. 25, 5, p. 1053–1056 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2014
  20. Published

    Synthesis, radiolabeling and in vivo evaluation of [C-11](R)-1-[4-[2-(4-methoxyphenyl)phenyl piperazin-1-yl]-3-(2-pyrazinyloxy)-2-propanol, a potential PET radioligand for the 5-HT7 receptor

    Hansen, H. D., Lacivita, E., Di Pilato, P., Herth, Matthias Manfred, Lehel, S., Ettrup, A., Andersen, V. L., Dyssegaard, A., De Giorgio, P., Perrone, R., Berardi, F., Colabufo, N. A., Niso, M., Knudsen, G. M. & Leopoldo, M., 22 May 2014, In: European Journal of Medicinal Chemistry. 79, p. 152-163 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    (11)C-labeling and preliminary evaluation of vortioxetine as a PET radioligand

    Andersen, V. L., Hansen, H. D., Herth, Matthias Manfred, Knudsen, Gitte Moos & Kristensen, Jesper Langgaard, 19 Apr 2014, In: Bioorganic & Medicinal Chemistry Letters. 24, 11, p. 2408-2411 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Design, synthesis, radiolabeling and in vivo evaluation of potential positron emission tomography (PET) radioligands for brain imaging of the 5-HT7 receptor

    Lacivita, E., Niso, M., Hansen, H. D., Di Pilato, P., Herth, Matthias Manfred, Lehel, S., Ettrup, A., Montenegro, L., Perrone, R., Berardi, F., Colabufo, N. A., Leopoldo, M. & Knudsen, G. M., 1 Mar 2014, In: Bioorganic & Medicinal Chemistry. 22, 5, p. 1736-1750 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Radiosynthesis and in vivo evaluation of novel radioligands for PET imaging of cerebral 5-HT7 receptors

    Hansen, H. D., Herth, Matthias Manfred, Ettrup, A., Andersen, V. L., Lehel, S., Dyssegaard, A., Kristensen, Jesper Langgaard & Knudsen, Gitte Moos, 24 Feb 2014, In: Journal of Nuclear Medicine. 55, 4, p. 640-646

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Accelerating preclinical PET-screening: reductive amination with [11C]methoxybenzaldehydes

    Herth, Matthias Manfred, Leth-Petersen, S., Lehel, S., Hansen, M., Gillings, N., Madsen, J. & Kristensen, Jesper Langgaard, 2014, In: R S C Advances. 41, p. 21347-21350 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. 2013
  26. Published

    Comparison of the 5-HT2A PET tracers, [F-18]MH.MZ and [F-18]altanserin

    Hansen, H., Herth, Matthias Manfred, Ettrup, A., Dyssegaard, A. & Knudsen, Gitte Moos, May 2013, p. S338-S338.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  27. Published

    Development of C-11-labeled oxindole derivatives for in vivo PET imaging of the 5-HT7 receptor

    Herth, Matthias Manfred, Hansen, H., Andersen, V. L., Volk, B., Ettrup, A., Antoni, F., Lehel, S., Dyssegaard, A., Kristensen, Jesper Langgaard & Knudsen, G. M., May 2013, p. S82-S82.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  28. Published

    Synthesis and evaluation of [C-11]CIMBI-712 and [C-11]CIMBI-772

    Andersen, V. L., Herth, Matthias Manfred, Hansen, H. D., Kristensen, Jesper Langgaard & Knudsen, Gitte Moos, May 2013, p. S101-S101.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  29. Published

    Development of a 11C-labeled tetrazine for rapid tetrazine–trans-cyclooctene ligation

    Herth, Matthias Manfred, Andersen, V. L., Lehel, S., Madsen, J., Knudsen, Gitte Moos & Kristensen, Jesper Langgaard, 2013, In: Chemical Communications. 49, p. 3805-3807 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Direct comparison of [18F]MH.MZ and [18F]altanserin for 5-HT2A receptor imaging with PET

    Hansen, H. D., Ettrup, A., Herth, Matthias Manfred, Dyssegaard, A., Ratner, C., Gillings, N. & Knudsen, G. M., 2013, In: Synapse. 67, 6, p. 328-337 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 33147568