Matthias Manfred Herth

Matthias Manfred Herth

Professor


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  1. Published

    Investigation of imaging the somatostatin receptor by opening the blood-brain barrier with melittin – A feasibility study using positron emission tomography and [64Cu]Cu-DOTATATE

    Andersen, Ida Vang, Bidesi, N. S. R., Shalgunov, Vladimir, Jørgensen, Jesper Tranekjær, Gustavsson, Karl Tobias, Strømgaard, Kristian, Ingemann Jensen, A. T., Kjær, Andreas & Herth, Matthias Manfred, 2024, In: Nuclear Medicine and Biology. 132-133, 5 p., 108905.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Optimization of Direct Aromatic 18F‐Labeling of Tetrazines

    Andersen, Ida Vang, García‐vázquez, R., Battisti, Umberto Maria & Herth, Matthias Manfred, 2022, In: Molecules. 27, 13, 11 p., 4022.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    (11)C-labeling and preliminary evaluation of pimavanserin as a 5-HT2A receptor PET-radioligand

    Andersen, V. L., Hansen, H. D., Herth, Matthias Manfred, Dyssegaard, A., Knudsen, G. M. & Kristensen, Jesper Langgaard, 20 Jan 2015, In: Bioorganic & Medicinal Chemistry Letters. 25, 5, p. 1053–1056 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    (11)C-labeling and preliminary evaluation of vortioxetine as a PET radioligand

    Andersen, V. L., Hansen, H. D., Herth, Matthias Manfred, Knudsen, Gitte Moos & Kristensen, Jesper Langgaard, 19 Apr 2014, In: Bioorganic & Medicinal Chemistry Letters. 24, 11, p. 2408-2411 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Palladium-mediated conversion of para-aminoarylboronic esters into para-aminoaryl- 11C-methanes

    Andersen, V. L., Herth, Matthias Manfred, Lehel, S., Knudsen, Gitte Moos & Kristensen, Jesper Langgaard, 2013, In: Tetrahedron Letters. 54, 3, p. 213-216 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Synthesis and evaluation of [C-11]CIMBI-712 and [C-11]CIMBI-772

    Andersen, V. L., Herth, Matthias Manfred, Hansen, H. D., Kristensen, Jesper Langgaard & Knudsen, Gitte Moos, May 2013, p. S101-S101.

    Research output: Contribution to conference › Conference abstract for conference › Research

  7. Published

    Development of the First Aliphatic 18F-Labeled Tetrazine Suitable for Pretargeted PET Imaging-Expanding the Bioorthogonal Tool Box

    Battisti, Umberto Maria, Bratteby, K., Jørgensen, Jesper Tranekjær, Hvass, Lars, Shalgunov, Vladimir, Mikula, H., Kjær, Andreas & Herth, Matthias Manfred, 2021, In: Journal of Medicinal Chemistry. 64, 20, p. 15297–15312

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Synergistic Experimental and Computational Investigation of the Bioorthogonal Reactivity of Substituted Aryltetrazines

    Battisti, Umberto Maria, García-Vázquez, R., Svatunek, D., Herrmann, B., Löffler, A., Mikula, H. & Herth, Matthias Manfred, 2022, In: Bioconjugate Chemistry. 33, 4, p. 608-624

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Accepted/In press

    Labeling of highly reactive tetrazines using [ 18F]SuFEx

    Battisti, Umberto Maria, Müller, Marius, García-Vázquez, R. & Herth, Matthias Manfred, 2023, (Accepted/In press) In: Synlett.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Synthesis and radiolabeling of a polar [125 I]I-1,2,4,5-tetrazine

    Bidesi, N., Shalgunov, Vladimir, Battisti, Umberto Maria, Hvass, Lars, Jørgensen, Jesper Tranekjær, Poulie, Christian Bernard Matthijs, Jensen, A. I., Kjær, Andreas & Herth, Matthias Manfred, 2023, In: Journal of Labelled Compounds and Radiopharmaceuticals. 66, 1, p. 22-30

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    The role of neuroimaging in Parkinson’s disease

    Bidesi, N. S. R., Andersen, Ida Vang, Windhorst, A. D., Shalgunov, Vladimir & Herth, Matthias Manfred, 2021, In: Journal of Neurochemistry. 159, 4, p. 660-689

    Research output: Contribution to journal › Review › Research › peer-review

  12. Published

    Quantitative Evaluation of a Multimodal Aptamer-Targeted Long-Circulating Polymer for Tumor Targeting

    Bohrmann, L., Burghardt, T., Rodríguez-Rodríguez, C., Herth, Matthias Manfred, Saatchi, K. & Häfeli, U. O., 2023, In: ACS Omega. 8, 12, p. 11003-11020

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    F-18-Radiolabeling and in vivo evaluation of two diverse glycomimetics using PET

    Bratteby, K., Torkelsson, E., L'Estrade, E. T., Peterson, K., Shalgunov, Vladimir, Xiong, M., Leffer, H., Zetterberg, F., Ohlsson, T., Gillings, N., Nilsson, U., Herth, Matthias Manfred & Erlandsson, M., May 2019, p. S533-S534.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  14. Published

    Aliphatic 18F-Radiofluorination: Recent Advances in the Labeling of Base-Sensitive Substrates**

    Bratteby, K., Shalgunov, Vladimir & Herth, Matthias Manfred, 2021, In: ChemMedChem. 16, 17, p. 2612-2622

    Research output: Contribution to journal › Review › Research › peer-review

  15. Published

    Fully Automated GMP-Compliant Synthesis of [18F]FE-PE2I

    Bratteby, K., Denholt, Charlotte Lund, Lehel, S., Petersen, I. N., Madsen, J., Erlandsson, M., Ohlsson, T., Herth, Matthias Manfred & Gillings, N., 2021, In: Pharmaceuticals. 14, 7, 17 p., 601.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Insights into Elution of Anion Exchange Cartridges: Opening the Path toward Aliphatic 18F-Radiolabeling of Base-Sensitive Tracers

    Bratteby, K., Shalgunov, Vladimir, Battisti, Umberto Maria, Petersen, I. N., Van Den Broek, S. L., Ohlsson, T., Gillings, N., Erlandsson, M. & Herth, Matthias Manfred, 2021, In: ACS Pharmacology and Translational Science. 4, 5, p. 1556–1566

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    In Vivo Veritas - 18F-radiolabeled glycomimetics allow insights into the pharmacological fate of galectin-3 inhibitors

    Bratteby, K., Torkelsson, E., Tampio L'Estrade, E., Peterson, K., Shalgunov, Vladimir, Xiong, M., Leffler, H., Zetterberg, F., Olsson, T. G., Gillings, N., Nilsson, U. J., Herth, Matthias Manfred & Erlandsson, M., 2020, In: Journal of Medicinal Chemistry. 63, 2, p. 747-755

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    The Chemogenetic Receptor Ligand Clozapine N-Oxide Induces in vivo Neuroreceptor Occupancy and Reduces Striatal Glutamate Levels

    Bærentzen, S., Casado-Sainz, A., Lange, D., Shalgunov, Vladimir, Tejada, I. M., Xiong, M., L'Estrade, E. T., Edgar, F. G., Lee, H., Herth, Matthias Manfred & Palner, M., 2019, In: Frontiers in Neuroscience. 13, 7 p., 187.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    18F-labeling and evaluation of novel MDL 100907 derivatives as potential 5-HT2A antagonists for molecular imaging

    Debus, F., Herth, Matthias Manfred, Piel, M., Buchholz, H., Bausbacher, N., Kramer, V., Lüddens, H. & Rösch, F., May 2010, In: Nuclear Medicine and Biology. 37, 4, p. 487-95 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Multifunctional Clickable Reagents for Rapid Bioorthogonal Astatination and Radio-Crosslinking

    Denk, C., Wilkovitsch, M., Aneheim, E., Herth, Matthias Manfred, Jensen, H., Lindegren, S. & Mikula, H., 1 Jan 2019, In: ChemPlusChem. 219, 84, p. 775-778 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    The Structural Combination of SIL and MODAG Scaffolds Fails to Enhance Binding to α-Synuclein but Reveals Promising Affinity to Amyloid β

    Di Nanni, A., Saw, R. S., Bowden, G. D., Bidesi, N. S. R., Bjerregaard-Andersen, K., Korat, Š., Herth, Matthias Manfred, Pichler, B. J., Herfert, K. & Maurer, A., 2023, In: Molecules. 28, 10, 20 p., 4001.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    A Fluorescent Probe as a Lead Compound for a Selective α-Synuclein PET Tracer: Development of a Library of 2-Styrylbenzothiazoles and Biological Evaluation of [18F]PFSB and [18F]MFSB

    Di Nanni, A., Saw, R. S., Battisti, Umberto Maria, Bowden, G. D., Boeckermann, A., Bjerregaard-Andersen, K., Pichler, B. J., Herfert, K., Herth, Matthias Manfred & Maurer, A., 2023, In: ACS Omega. 8, 34, p. 31450–31467

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    In vitro and in vivo characterization of dibenzothiophene derivatives [125I]iodo-ASEM and [18F]ASEM as radiotracers of homo- And heteromeric α7 nicotinic acetylcholine receptors

    Donat, C. K., Hansen, H. H., Hansen, H. D., Mease, R. C., Horti, A. G., Pomper, M. G., L’Estrade, E. T., Herth, Matthias Manfred, Peters, D., Knudsen, Gitte Moos & Mikkelsen, Jens D., 1 Jan 2020, In: Molecules. 25, 6, 19 p., 1425.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Radiolabelling and Evaluation of a Sc-44-labelled DOTA Tetrazine for Pretargeted PET Imaging

    Edem, P., Sinnes, J., Pektor, S., Bausbacher, N., Rossin, R., Abdoireza, Y., Kjær, Andreas, Valliant, J., Robillard, M., Roesch, F. & Herth, Matthias Manfred, 1 May 2018. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  25. Published

    Evaluation of the inverse electron demand Diels-Alder reaction in rats using a scandium-44-labelled tetrazine for pretargeted PET imaging

    Edem, P. E., Sinnes, J., Pektor, S., Bausbacher, N., Rossin, R., Yazdani, A., Miederer, M., Kjær, Andreas, Valliant, J. F., Robillard, M. S., Rösch, F. & Herth, Matthias Manfred, 28 May 2019, In: EJNMMI Research. 9, 1, 8 p., 49.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    In Vivo Radionuclide Generators for Diagnostics and Therapy

    Edem, P. E., Fonslet, J., Kjær, Andreas, Herth, Matthias Manfred & Severin, G., 2016, In: Bioinorganic Chemistry and Applications. 2016, p. 1-9 9 p., 6148357.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Fluorine-18 radiolabeling strategies-advantages and disadvantages of currently applied labeling methods

    Edem, P. E., Steen, E. J. L., Kjær, Andreas & Herth, Matthias Manfred, 2019, Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates. Elsevier, p. 29-103

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  28. Published

    Evaluation of a 68Ga-Labeled DOTA-Tetrazine as a PET Alternative to 111In-SPECT Pretargeted Imaging

    Edem, P. E., Jørgensen, Jesper Tranekjær, Norregaard, K., Rossin, R., Yazdani, A., Valliant, J. F., Robillard, M., Herth, Matthias Manfred & Kjær, Andreas, 2020, In: Molecules. 25, 3, 14 p., 463.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Synthesis, radiofluorination, and preliminary evaluation of the potential 5-HT2A receptor agonists [18 F]Cimbi-92 and [18 F]Cimbi-150

    Edgar, F. G., Hansen, H. D., Leth-Petersen, S., Ettrup, A., Kristensen, Jesper Langgaard, Knudsen, Gitte Moos & Herth, Matthias Manfred, Oct 2017, In: Journal of Labelled Compounds and Radiopharmaceuticals. 60, 12, p. 586-591 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    A pilot study of cerebral metabolism and serotonin 5-HT2A receptor occupancy in rats treated with the psychedelic tryptamine DMT in conjunction with the MAO inhibitor harmine

    Egger, K., Gudmundsen, F., Jessen, N. S., Baun, C., Poetzsch, S. N., Shalgunov, Vladimir, Herth, Matthias Manfred, Quednow, B. B., Martin-Soelch, C., Dornbierer, D., Scheidegger, M., Cumming, P. & Palner, M., 2023, In: Frontiers in Pharmacology. 14, 12 p., 1140656.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Development and Preclinical Evaluation of [211At]PSAt-3-Ga: An Inhibitor for Targeted α-Therapy of Prostate Cancer.

    El Fakiri, M., Ayada, N., Müller, Marius, Hvass, Lars, Gamzov, T. H., Clausen, Anne Skovsbo, Geis, N. M., Steinacker, N., Hansson, E., Lindegren, S., Aneheim, E., Jensen, H., Eder, A., Jensen, Andreas, Poulie, Christian Bernard Matthijs, Kjær, Andreas, Eder, M. & Herth, Matthias Manfred, 2024, In: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 65, 4, p. 593-599

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Development of an F-18-labelled 5-HT2A receptor agonist PET radioligand

    Ettrup, A., Hansen, M., Gillings, N., Dyssegaard, A., Lehel, S., Hansen, H. D., Herth, Matthias Manfred, Madsen, J., Kristensen, J. & Knudsen, G. M., Aug 2012, In: Journal of Cerebral Blood Flow and Metabolism. 32, p. S109-S109

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Radiosynthesis and in vivo evaluation of a series of substituted 11C-phenethylamines as 5-HT2A agonist PET tracers

    Ettrup, A., Hansen, M., Santini, M. A., Paine, J. S., Gillings, N., Palner, M., Lehel, S., Herth, Matthias Manfred, Madsen, J., Kristensen, Jesper Langgaard, Begtrup, M. & Knudsen, Gitte Moos, 1 Apr 2011, In: European Journal of Nuclear Medicine and Molecular Imaging. 38, 4, p. 681-693

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Radiolabeled albumin through SNAr of cysteines as a potential pretargeting theranostic agent

    Fischer, Niklas Henrik, van den Broek, S. I. L. I., Herth, Matthias Manfred & Diness, Frederik, 2022, In: RSC Advances. 12, 54, p. 35032-35036

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Development of18F-Labeled Bispyridyl Tetrazines for In Vivo Pretargeted PET Imaging

    García-Vázquez, R., Jørgensen, Jesper Tranekjær, Bratteby, K. E., Shalgunov, Vladimir, Hvass, Lars, Herth, Matthias Manfred, Kjær, Andreas & Battisti, Umberto Maria, 2022, In: Pharmaceuticals. 15, 2, 28 p., 245.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Direct Cu-mediated aromatic18F-labeling of highly reactive tetrazines for pretargeted bioorthogonal PET imaging

    García-Vázquez, R., Battisti, Umberto Maria, Jørgensen, Jesper Tranekjær, Shalgunov, Vladimir, Hvass, Lars, Stares, D. L., Petersen, I. N., Crestey, F., Löffler, A., Svatunek, D., Kristensen, Jesper Langgaard, Mikula, H., Kjær, Andreas & Herth, Matthias Manfred, 2021, In: Chemical Science. 12, 35, p. 11668-11675

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Recent Advances in the Development of Tetrazine Ligation Tools for Pretargeted Nuclear Imaging

    García-Vázquez, R., Battisti, Umberto Maria & Herth, Matthias Manfred, 2022, In: Pharmaceuticals. 15, 6, 25 p., 685.

    Research output: Contribution to journal › Review › Research › peer-review

  38. Published

    [11C]Carboxylated Tetrazines for Facile Labeling of Trans-Cyclooctene-Functionalized PeptoBrushes

    García-Vázquez, R., Battisti, Umberto Maria, Shalgunov, Vladimir, Schäfer, G., Barz, M. & Herth, Matthias Manfred, 2022, In: Macromolecular Rapid Communications. 43, 12, 7 p., 2100655.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Training the next generation of radiopharmaceutical scientists

    Gee, A. D., Andersson, J., Bhalla, R., Choe, Y. S., Dick, D. W., Herth, M. M., Hostetler, E. D., Jauregui-Haza, U. J., Huang, Y-Y., James, M. L., Jeong, J. M., Korde, A., Kuge, Y., Kung, H. F., Lapi, S. E., Osso, J. A., Parent, E., Patt, M., Pricile, E. F., Riss, P. J. & 8 others, Santos-Oliveira, R., Taylor, S., Vasdev, N., Vercouillie, J., Wadsak, W., Yang, Z., Zhu, H. & Scott, P. J. H., 2020, In: Nuclear Medicine and Biology. 88-89, p. 10-13 4 p.

    Research output: Contribution to journal › Editorial › Research

  40. Published

    Radionuclide Imaging for Neuroscience: Current Opinion and Future Directions

    Gee, A. D., Herth, Matthias Manfred, James, M. L., Korde, A., Scott, P. J. H. & Vasdev, N., 2020, In: Molecular Imaging. 19, 9 p., 1536012120936397.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    An Improved Radiolabelling Strategy for the 5-HT2A Agonist, [C-11]Cimbi-36

    Gillings, N., Lehel, S., Herth, Matthias Manfred, Leth-Petersen, S., Madsen, J., Gabel-Jensen, C. & Kristensen, Jesper Langgaard, 15 May 2015, In: Journal of Labelled Compounds and Radiopharmaceuticals. 58, p. S296-S296 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  42. Published

    Autoradiography as a Simple and Powerful Method for Visualization and Characterization of Pharmacological Targets

    Griem-Krey, Nane, Klein, A. B., Herth, Matthias Manfred & Wellendorph, Petrine, 12 Mar 2019, In: Journal of visualized experiments : JoVE. 145, 11 p., e58879.

    Research output: Contribution to journal › Journal article › Communication

  43. Published

    Comparison of the 5-HT2A PET tracers, [F-18]MH.MZ and [F-18]altanserin

    Hansen, H., Herth, Matthias Manfred, Ettrup, A., Dyssegaard, A. & Knudsen, Gitte Moos, May 2013, p. S338-S338.

    Research output: Contribution to conference › Conference abstract for conference › Research

  44. Published

    Labeling and preliminary in vivo evaluation of the 5-HT7 receptor selective agonist [(11)C]E-55888

    Hansen, H. D., Andersen, V. L., Lehel, S., Magnussen, J. H., Dyssegaard, A., Stroth, N., Kristensen, Jesper Langgaard, Knudsen, G. M. & Herth, Matthias Manfred, 1 May 2015, In: Bioorganic & Medicinal Chemistry Letters. 25, 9, p. 1901-4 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Radiosynthesis and in vivo evaluation of novel radioligands for PET imaging of cerebral 5-HT7 receptors

    Hansen, H. D., Herth, Matthias Manfred, Ettrup, A., Andersen, V. L., Lehel, S., Dyssegaard, A., Kristensen, Jesper Langgaard & Knudsen, Gitte Moos, 24 Feb 2014, In: Journal of Nuclear Medicine. 55, 4, p. 640-646

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    In vivo PET imaging of cerebral 5-HT7 receptors with novel radioligands

    Hansen, H. D., Herth, Matthias Manfred, Ettrup, A., Szabolcs, L., Dyssegaard, A., Kristensen, Jesper Langgaard & Knudsen, G. M., Aug 2012, In: Journal of Cerebral Blood Flow and Metabolism. 32, p. S126-S127

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Synthesis, radiolabeling and in vivo evaluation of [C-11](R)-1-[4-[2-(4-methoxyphenyl)phenyl piperazin-1-yl]-3-(2-pyrazinyloxy)-2-propanol, a potential PET radioligand for the 5-HT7 receptor

    Hansen, H. D., Lacivita, E., Di Pilato, P., Herth, Matthias Manfred, Lehel, S., Ettrup, A., Andersen, V. L., Dyssegaard, A., De Giorgio, P., Perrone, R., Berardi, F., Colabufo, N. A., Niso, M., Knudsen, G. M. & Leopoldo, M., 22 May 2014, In: European Journal of Medicinal Chemistry. 79, p. 152-163 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Evaluation of [18F]2FP3 in pigs and non-human primates

    Hansen, H. D., Constantinescu, C. C., Barret, O., Herth, Matthias Manfred, Magnussen, J. H., Lehel, S., Dyssegaard, A., Colomb, J., Billard, T., Zimmer, L., Tamagnan, G. & Knudsen, Gitte Moos, 2019, In: Journal of Labelled Compounds and Radiopharmaceuticals. 62, 1, p. 34-42

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Direct comparison of [18F]MH.MZ and [18F]altanserin for 5-HT2A receptor imaging with PET

    Hansen, H. D., Ettrup, A., Herth, Matthias Manfred, Dyssegaard, A., Ratner, C., Gillings, N. & Knudsen, G. M., 2013, In: Synapse. 67, 6, p. 328-337 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    72/74As-labeling of HPMA based polymers for long-term in vivo PET imaging

    Herth, Matthias Manfred, Barz, M., Jahn, M., Zentel, R. & Rösch, F., 15 Sep 2010, In: Bioorganic & Medicinal Chemistry Letters. 20, 18, p. 5454-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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