Sara Marie Øie Solbak

Sara Marie Øie Solbak

Assistant Professor


  1. 2017
  2. Insights from engineering the Affibody-Fc interaction with a computational-experimental method.

    Nosrati, M., Solbak, Sara Marie Øie, Nordesjö, O., Nissbeck, M., Dourado, D., Andersson, K., Housaindokht, M., Löfblom, J., Virtanen, A., Danielson, U. & Flores, S., Sep 2017, In: Protein engineering, design & selection : PEDS.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Characterization of interactions between hepatitis C virus NS5B polymerase, annexin A2 and RNA - effects on NS5B catalysis and allosteric inhibition.

    Solbak, Sara Marie Øie, Abdurakhmanov, E., Vedeler, A. & Danielson, U., Dec 2017, In: Virology Journal.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2019
  5. Published

    A Comparative Assessment Study of Known Small-Molecule Keap1-Nrf2 Protein-Protein Interaction Inhibitors: Chemical Synthesis, Binding Properties, and Cellular Activity

    Tran, K. T., Pallesen, J. S., Solbak, Sara Marie Øie, Narayanan, Dilip, Baig, A., Zang, J., Aguayo-Orozco, A., Carmona, R., Garcia, A. & Bach, Anders, 2019, In: Journal of Medicinal Chemistry. 62, 17, p. 8028-8052

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Molecular architecture of the Jumonji C family histone demethylase KDM5B

    Dorosz, J., Kristensen, L. H., Aduri, N. G., Mirza, Osman Asghar, Lousen, R., Bucciarelli, S., Mehta, V., Sellés Baiget, Selene, Solbak, Sara Marie Øie, Bach, Anders, Mesa, Pablo, Hernandez, P. A., Montoya, Guillermo, Nguyen, T. T. T. N., Rand, Kasper Dyrberg, Boesen, T. & Gajhede, Michael, 2019, In: Scientific Reports. 9, 13 p., 4019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2020
  8. Published

    Developing Inhibitors of the p47phox-p22phox Protein-Protein Interaction by Fragment-Based Drug Discovery

    Solbak, Sara Marie Øie, Zang, J., Narayanan, Dilip, Høj, L. J., Bucciarelli, S., Softley, C., Meier, S., Langkilde, Annette Eva, Gotfredsen, C. H., Sattler, M. & Bach, Anders, 2020, In: Journal of Medicinal Chemistry. 63, 3, p. 1156-1177

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Fibrin fragment E potentiates TGF-beta-induced myofibroblast activation and recruitment

    Fuchs, P. O., Calitz, C., Pavlovic, N., Binet, F., Solbak, Sara Marie Øie, Danielson, U. H., Kreuger, J., Heindryckx, F. & Gerwins, P., Aug 2020, In: Cellular Signalling. 72, 12 p., 109661.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The dynamics of linear polyubiquitin

    Jussupow, A., Messias, A. C., Stehle, R., Geerlof, A., Solbak, Sara Marie Øie, Paissoni, C., Bach, Anders, Sattler, M. & Camilloni, C., Oct 2020, In: Science Advances. 6, 42, 13 p., eabc3786.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2021
  12. Published

    Deconstructing Noncovalent Kelch-like ECH-Associated Protein 1 (Keap1) Inhibitors into Fragments to Reconstruct New Potent Compounds

    Pallesen, J. S., Narayanan, Dilip, Tran, K. T., Solbak, Sara Marie Øie, Marseglia, G., Sørensen, L. M. E., Høj, L. J., Munafò, F., Carmona, R. M. C., Garcia, A. D., Desu, H. L., Brambilla, R., Johansen, Tommy Nørskov, Popowicz, G. M., Sattler, M., Gajhede, Michael & Bach, Anders, 2021, In: Journal of Medicinal Chemistry. 64, 8, p. 4623–4661

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain

    Leurs, U., Klein, A. B., McSpadden, E. D., Griem-Krey, N., Solbak, S. M. Ø., Houlton, J., Villumsen, I. S., Vogensen, S. B., Hamborg, L., Gauger, S. J., Palmelund, L. B., Larsen, A. S. G., Shehata, M. A., Kelstrup, C. D., Olsen, J. V., Bach, A., Burnie, R. O., Kerr, D. S., Gowing, E. K., Teurlings, S. M. W. & 9 others, Chi, C. C., Gee, C. L., Frølund, Bente, Kornum, Birgitte Rahbek, van Woerden, G. M., Clausen, Rasmus Prætorius, Kuriyan, J., Clarkson, A. N. & Wellendorph, Petrine, 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 31, 9 p., e2108079118.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Identification of novel fragments binding to the PDZ1-2 domain of PSD-95

    Zang, J., Ye, F., Solbak, Sara Marie Øie, Høj, L. J., Zhang, M. & Bach, Anders, 2021, In: ChemMedChem. 16, 6, p. 949-954

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 157688952