Søren Brøgger Christensen

Søren Brøgger Christensen

Professor emeritus, Professor, emeritus

Member of:

    ORCID: 0000-0002-5773-6874

    Publication year:
    All
    51 - 75 out of 182Page size: 25
    Sort by: 1st author
    1. Published

      Engineering a prostate-specific membrane antigen-activated tumor endothelial cell prodrug for cancer therapy

      Denmeade, S. R., Mhaka, A. M., Rosen, D. M., Brennen, W. N., Dalrymple, S., Dach, I., Olesen, C., Gurel, B., DeMarzo, A. M., Wilding, G., Carducci, M. A., Dionne, C. A., Møller, J. V., Nissen, P., Christensen, Søren Brøgger & Isaacs, J. T., 27 Jun 2012, In: Science Translational Medicine. 4, 140, p. 140ra86

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Prostate-specific antigen-activated thapsigargin prodrug as targeted therapy for prostate cancer

      Denmeade, S. R., Jakobsen, C. M., Janssen, S., Khan, S. R., Garrett, E. S., Lilja, H., Christensen, Søren Brøgger & Isaacs, J. T., 2 Jul 2003, In: National Cancer Institute. Journal (Online). 95, 13, p. 990-1000 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Thapsigargin, origin, chemistry, structure-activity relationships and prodrug development.

      Doan, T. Q. N. & Christensen, Søren Brøgger, Oct 2015, In: Current Pharmaceutical Design. 21, 38, p. 5505-5517 13 p.

      Research output: Contribution to journal › Review › Research › peer-review

    4. Published

      Chemo- and regioselective functionalization of nortrilobolide: application for semi-synthesis of the natural product 2-acetoxytrilobolide

      Doan, T. Q. N., Crestey, F., Olsen, C. E. & Christensen, Søren Brøgger, 2015, In: Journal of Natural Products. 78, 6, p. 1406-1414

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Novel thapsigargin analogues and methods of preparing them

      Doan, T. Q. N., Christensen, Søren Brøgger & Crestey, F. L. J., 30 Dec 2015, Patent No. WO2015197860 A2, Priority date 27 Jun 2014, Priority No. DK20140070395 20140627

      Research output: Patent

    6. Published

      Antiplasmodial Constituents of Cajanus cajan

      Duker-Eshun, G., Jaroszewski, J. W., Asomaning, W. A., Oppong-Boachie, F. & Christensen, Søren Brøgger, 1 Feb 2004, In: Phytotherapy Research. 18, 2, p. 128-130 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Targeting Toxins toward Tumors

      Franzyk, Henrik & Christensen, Søren Brøgger, 2021, In: Molecules. 26, 5, 23 p., 1292.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Noter til bioorganisk kemi M23-1

      Franzyk, Henrik, Christensen, Søren Brøgger & Jaroszewski, J. W., 2007, København: Københavns Universitet, Det Farmaceutiske Fakultet, Institut for Medicinalkemi.

      Research output: Book/Report › Compendium/lecture notes › Education

    9. Published

      Ca2+ influx in human T lymphocytes is induced independently of inositol phosphate production by mobilization of intracellular Ca2+ stores. A study with the Ca2+ endoplasmic reticulum‐ATPase inhibitor thapsigargin

      Gouy, H., Cefai, D., Christensen, Søren Brøgger, Debré, P. & Bismuth, G., Oct 1990, In: European Journal of Immunology. 20, 10, p. 2269-2275 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Cyclic AMP- and inositol phosphate-independent inhibition of Ca2+ influx by cholera toxin in CDS-stimulated jurkat T cells: A study with a cholera toxin-resistant cell variant and the Ca2+ endoplasmic reticulum-ATPase inhibitor thapsigargin

      Gouy, H., Cefai, D., Christensen, Søren Brøgger, Debre, P. & Bismuth, G., 1 Aug 1991, In: Journal of Immunology. 147, 3, p. 757-766 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Amino acid containing thapsigargin analogues deplete androgen receptor protein via synthesis inhibition and induce the death of prostate cancer cells

      Griend, D. J. V., Antony, L., Dalrymple, S. L., Xu, Y., Christensen, Søren Brøgger, Denmeade, S. R. & Isaacs, J. T., 2009, In: Molecular Cancer Therapeutics. 8, 5, p. 1340-1349

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Thapsigargin-induced increase in cytoplasmic Ca2+concentration and aldosterone production in rat adrenal glomerulosa cells: Interaction with potassium and angiotensin-II

      Hajnóczky, G., Várnai, P., Holló, Z., Christensen, Søren Brøgger, Balla, T., Enyedi, P. & Spät, A., 1 May 1991, In: Endocrinology. 128, 5, p. 2639-2644 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Thapsigargin, a histamine secretagogue, is a non-12-O-tetradecanolphorbol-13-acetate (TPA) type tumor promoter in two-stage mouse skin carcinogenesis

      Hakii, H., Fujiki, H., Suganuma, M., Nakayasu, M., Tahira, T., Sugimura, T., Scheuer, P. J. & Christensen, Søren Brøgger, 1 Jun 1986, In: Journal of Cancer Research and Clinical Oncology. 111, 3, p. 177-181 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Metformin, an Anthropogenic Contaminant of Seidlitzia rosmarinus Collected in a Desert Region near the Gulf of Aqaba, Sinai Peninsula

      Hassan, A. R., El-Kousy, S. M., El-Toumy, S. A., Frydenvang, Karla Andrea, Tung, T. T., Olsen, J., Nielsen, J. & Christensen, Søren Brøgger, 27 Oct 2017, In: Journal of Natural Products. 80, p. 2830-2834 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      A new flavonol glycoside and other flavonoids from the aerial parts of Taverniera aegyptiaca

      Hassan, A. R., Amer, K. F., El-Toumy, S. A., Nielsen, J. & Christensen, Søren Brøgger, 2019, In: Natural Product Research. 33, 8, p. 1135-1139

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Chalcone inhibitors of the NorA efflux pump in Staphylococcus aureus whole cells and enriched everted membrane vesicles

      Holler, J. G., Slotved, H., Mølgaard, Per, Olsen, C. E. & Christensen, Søren Brøgger, 2012, In: Bioorganic & Medicinal Chemistry. 20, 14, p. 4514 - 4521 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Novel inhibitory activity of the Staphylococcus aureus NorA efflux pump by a kaempferol rhamnoside isolated from Persea lingue Nees

      Holler, J. G., Christensen, Søren Brøgger, Slotved, H., Rasmussen, H. B., Guzman, A., Olsen, C. E., Petersen, B. & Mølgaard, Per, 2012, In: Journal of Antimicrobial Chemotherapy. 67, 5, p. 1138 - 1144 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Mipsagargin: The Beginning—Not the End—of Thapsigargin Prodrug-Based Cancer Therapeutics

      Isaacs, J. T., Brennen, W. N., Christensen, Søren Brøgger & Denmeade, S. R., 2021, In: Molecules. 26, 24, 7469.

      Research output: Contribution to journal › Review › Research › peer-review

    19. Published

      An attempt to develop an ELISA against the sesquiterpene lactone thapsigargin

      Jager, A. K., Smitt, U. W., Nyman, U. & Christensen, Søren Brøgger, 1 Dec 1993, In: Planta Medica. 59, 7 SUPPL., p. A679

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      A configurational and conformational study of aframodial and its diasteriomers via experimental and theoretical VA and VCD spectroscopies

      Jalkanen, K. J., Gale, J. D., Lassen, P. R., Hemmingsen, Lars Bo Stegeager, Rodarte, A., Degtyarenko, I. M., Nieminen, R. M., Knapp-Mohammady, M., Suhai, S. & Christensen, Søren Brøgger, 2008, In: Theoretical Chemistry Accounts. 119, 1-3, p. 177-190 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Pharmacokinetics, biodistribution, and antitumor efficacy of a human glandular kallikrein 2 (hK2)-activated thapsigargin prodrug

      Janssen, S., Rosen, D. M., Ricklis, R. M., Dionne, C. A., Lilja, H., Christensen, Søren Brøgger, Isaacs, J. T. & Denmeade, S. R., 1 Mar 2006, In: Prostate. 66, 4, p. 358-368 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Screening a combinatorial peptide library to develop a human glandular kallikrein 2-activated prodrug as targeted therapy for prostate cancer

      Janssen, S., Jakobsen, C. M., Rosen, D. M., Ricklis, R. M., Reineke, U., Christensen, Søren Brøgger, Lilja, H. & Denmeade, S. R., 1 Nov 2004, In: Molecular Cancer Therapeutics. 3, 11, p. 1439-1450 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Lægemidler fra naturstoffer: fortid eller fremtid?

      Jaroszewski, J. W., Christensen, Søren Brøgger, Franzyk, Henrik, Stærk, Dan & Ziegler, H., 2008, In: Lægemiddelforskning. p. 4-6

      Research output: Contribution to journal › Journal article › Communication

    24. Published

      Iminolactones as Tools for Inversion of the Absolute Configuration of alpha-Amino Acids and as Inhibitors of Cancer Cell Proliferation

      Jensen, C. M., Chow, H., Chen, M., Zhai, L., Frydenvang, Karla Andrea, Liu, H., Franzyk, Henrik & Christensen, Søren Brøgger, 2016, In: European Journal of Medicinal Chemistry. 114, p. 118-133 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Hydrophilic carboxylic acids and iridoid glycosides in the juice of American and European cranberries (Vaccinium macrocarpon and V. oxycoccos), lingonberries (V. vitis-idaea), and blueberries (V. myrtillus)

      Jensen, H. D., Krogfelt, K. A., Cornett, Claus, Hansen, S. H. & Christensen, Søren Brøgger, 2002, In: Journal of Agricultural and Food Chemistry. 50, 23, p. 6871-4 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    Previous 1 2 3 4 5 6 7 8 Next

    ID: 1300951