Stephan Pless

Stephan Pless

Professor


  1. 2020
  2. Published

    Mechanism and site of action of big dynorphin on ASIC1a

    Borg, C. B., Braun, N., Heusser, Stephanie, Bay, Y., Weis, D., Galleano, I., Lund, Camilla, Tian, W., Haugaard-Kedström, L. M., Bennett, Eric Paul, Lynagh, T., Strømgaard, Kristian, Andersen, J. & Pless, Stephan, 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 13, p. 7447-7454

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Peptide Inhibitors of the α-Cobratoxin-Nicotinic Acetylcholine Receptor Interaction

    Lynagh, T., Kiontke, S., Meyhoff-Madsen, M., Gless, B. H., Johannesen, J., Kattelmann, S., Christiansen, A., Dufva, M., Laustsen, A. H., Devkota, K., Olsen, Christian Adam, Kuemmel, D., Pless, Stephan & Lohse, B., 2020, In: Journal of Medicinal Chemistry. 63, 22, p. 13709-13718 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Structure of the human sodium leak channel NALCN

    Kschonsak, M., Chua, H. C., Noland, C. L., wbv551, wbv551, Clairfeuille, T., Bahlke, O. Ø., Ameen, A. O., Li, Z. R., Arthur, C. P., Ciferri, C., Pless, Stephan & Payandeh, J., 2020, In: Nature. 587, p. 313-318

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The current chemical biology tool box for studying ion channels

    Braun, N., Sheikh, Zeshan Pervez & Pless, Stephan, 2020, In: The Journal of Physiology. 598, 20, p. 4455-4471 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2019
  7. Published

    Molecular determinants for agonist recognition and discrimination in P2X2 receptors

    Gasparri, F., Wengel, J., Grutter, T. & Pless, Stephan, 24 May 2019, In: Journal of General Physiology. 151, 7, p. 898–911

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    A Semi-Synthetic Approach to Engineer Ligand- and Voltage-Gated Ion Channels in Live Cells

    Khoo, K. K., Galleano, I. & Pless, Stephan, 2019, p. 274A-274A.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  9. Published

    Elucidating the Function and Cell-Specific Interactions of P2X7 Receptor Variants Linked to Mental Disorders

    Poulsen, Mette Homann, Fang, J. & Pless, Stephan, 2019, p. 109A-110A.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  10. Published

    Indirect Determinants of Ion Selectivity in Acid-Sensing Ion Channels and Epithelial Sodium Channels

    Sheikh, Zeshan Pervez, Lynagh, T., Kristensen, Anders Skov & Pless, Stephan, 2019, p. 110A-110A.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  11. 2018
  12. Published

    Probing Backbone Hydrogen Bonds in Proteins by Amide-to-Ester Mutations

    Sereikaité, Vita, Jensen, T. M. T., Bartling, Christian Reinhard Otto, Jemth, P., Pless, Stephan & Strømgaard, Kristian, 18 Oct 2018, In: ChemBioChem. 19, 20, p. 2136-2145

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published

    One drug-sensitive subunit is sufficient for a nearmaximal retigabine effect in KCNQ channels

    Yau, M. C., Kim, R. Y., Wang, C. K., Li, J., Ammar, T., Yang, R. Y., Pless, Stephan & Kurata, H. T., 1 Oct 2018, In: Journal of General Physiology. 215, 10, p. 1421-1431 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Four drug-sensitive subunits are required for maximal effect of a voltage sensor-targeted KCNQ opener

    Wang, A. W., Yau, M. C., Wang, C. K., Sharmin, N., Yang, R. Y., Pless, Stephan & Kurata, H. T., 30 Aug 2018, In: Journal of General Physiology. 150, 10, p. 1432-1443 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Acid-sensing ion channels emerged over 600 Mya and are conserved throughout the deuterostomes

    Lynagh, T., Mikhaleva, Y., Colding, J. M., Glover, J. C. & Pless, Stephan, 14 Aug 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 33, p. 8430-8435

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Unexplained cardiac arrest: a tale of conflicting interpretations of KCNQ1 genetic test results

    Chua, H. C., Servatius, H., Asatryan, B., Schaller, A., Rieubland, C., Noti, F., Seiler, J., Roten, L., Baldinger, S. H., Tanner, H., Fuhrer, J., Haeberlin, A., Lam, A., Pless, Stephan & Medeiros-Domingo, A., 1 Aug 2018, In: Clinical Research in Cardiology. 107, 8, p. 670-678 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    A tale of ligands big and small: An update on how pentameric ligand-gated ion channels interact with agonists and proteins

    Pless, Stephan & Sivilotti, L. G., 1 Apr 2018, In: Current Opinion in Physiology. 2, p. 19-26 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  18. Published

    How an intrinsic ligand tunes the activity of a potassium channel

    Khoo, K. K. & Pless, Stephan, 22 Mar 2018, In: Journal of General Physiology. 150, 4, p. 517-520

    Research output: Contribution to journalComment/debateResearchpeer-review

  19. Published

    High-Sensitivity Fluorometry to Resolve Ion Channel Conformational Dynamics

    Wulf, M. & Pless, Stephan, 6 Feb 2018, In: Cell Reports. 22, 6, p. 1615-1626 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Inhibitor-Induced Conformational Changes in ASIC1A

    Lund, Camilla, Borg, C. B., Lynagh, T. & Pless, Stephan, 2 Feb 2018, p. 130A-130A.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  21. Published

    Ion Selectivity in Acid-Sensing Ion Channels and Epithelial Sodium Channels

    Sheikh, Zeshan Pervez, Lynagh, T. P. & Pless, Stephan, 2 Feb 2018, p. 24A-24A.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  22. Published

    Peptide Modulation of Acid-Sensing Ion Channels

    Borg, C. B., Haugaard-Kedstrom, L. M., Lynagh, T., Strømgaard, Kristian & Pless, Stephan, 2 Feb 2018, p. 130A-130A.

    Research output: Contribution to conferencePosterResearch

  23. Published

    Phenotypic Spectrum of HCN4 Mutations: A Clinical Case

    Servatius, H., Porro, A., Pless, Stephan, Schaller, A., Asatryan, B., Tanner, H., de Marchi, S. F., Roten, L., Seiler, J., Haeberlin, A., Baldinger, S. H., Noti, F., Lam, A., Fuhrer, J., Moroni, A. & Medeiros-Domingo, A., Feb 2018, In: Circulation. Genomic and precision medicine. 11, 2, e002033.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Investigation of Agonist Recognition and Channel Properties in a Flatworm Glutamate-Gated Chloride Channel

    Callau-Vázquez, D., Pless, Stephan & Lynagh, T., 2018, In: Biochemistry. 57, 8, p. 1360-1368

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. 2017
  26. Published

    PIP2 mediates functional coupling and pharmacology of neuronal KCNQ channels

    Kim, R. Y., Pless, Stephan & Kurata, H. T., 23 Oct 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 45, p. E9702–E9711

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Molecular Basis for Allosteric Inhibition of Acid-Sensing Ion Channel 1a by Ibuprofen

    Lynagh, T., Romero-Rojo, J. L., Lund, Camilla & Pless, Stephan, 12 Oct 2017, In: Journal of Medicinal Chemistry. 60, 19, p. 8192-8200 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    A selectivity filter at the intracellular end of the acid-sensing ion channel pore

    Lynagh, T., Flood, E., Boiteux, C., Wulf, M., Komnatnyy, V. V., Colding, J. M., Allen, T. W. & Pless, Stephan, 12 May 2017, In: eLife. 6, 21 p., 24630.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    A New Method to Detect Intra- and Extracellular Conformational Changes in Ion Channels with High Temporal Resolution

    Wulf, M. & Pless, Stephan, 3 Feb 2017, In: Biophysical Journal. 12, 3, p. 285A-285A

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

ID: 93715174