Ole Thastrup

Ole Thastrup

Emeritus

  • Administration and Operations

    Jagtvej 160

    2100 København Ø

    Mobile: +4522115399

  1. Stimulatory effect of thapsigargin, a non-TPA-type tumor promoter, on arachidonic acid metabolism in the murine keratinocyte line HEL30 and on epidermal cell proliferation in vivo as compared to the effects of phorbol ester TPA

    Marks, F., Hanke, B., Thastrup, Ole & Fürstenberger, G., 1991, In: Carcinogenesis. 12, 8, p. 1491-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Structure-activity relationships of analogues of thapsigargin modified at O-11 and O-12

    Nielsen, S. F., Thastrup, Ole, Pedersen, R., Olsen, C. E. & Christensen, Søren Brøgger, 1995, In: Journal of Medicinal Chemistry. 38, 2, p. 272-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Structure-activity relationships of thapsigargin

    Nielsen, S. F., Andersen, A., Olsen, C. E., Treimann, M., Thastrup, Ole & Christensen, Søren Brøgger, 1 Dec 1993, In: Planta Medica. 59, 7 SUPPL., p. A678-A679

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Thapsigargin: a novel molecular probe for studying intracellular calcium release and storage

    Thastrup, Ole, Dawson, A. P., Scharff, O., Foder, B., Cullen, P. J., Drøbak, B. K., Bjerrum, P. J., Christensen, Søren Brøgger & Hanley, M. R., 1994, In: Agents and Actions. 43, 3-4, p. 187-93 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Thapsigargin, a new calcium-dependent epithelial anion secretagogue

    Brayden, D. J., Hanley, M. R., Thastrup, Ole & Cuthbert, A. W., 1989, In: British Journal of Pharmacology. 98, 3, p. 809-16 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase

    Thastrup, Ole, Cullen, P. J., Drøbak, B. K., Hanley, M. R. & Dawson, A. P., 1990, In: Proceedings of the National Academy of Sciences of the United States of America. 87, 7, p. 2466-70 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Thapsigargin, but not caffeine, blocks the ability of thyrotropin-releasing hormone to release Ca2+ from an intracellular store in GH4C1 pituitary cells

    Law, G. J., Pachter, J. A., Thastrup, Ole, Hanley, M. R. & Dannies, P. S., 1990, In: Biochemical Journal. 267, 2, p. 359-64 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The ability of thapsigargin and thapsigargicin to activate cells involved in the inflammatory response

    Ali, H., Christensen, Søren Brøgger, Foreman, J. C., Pearce, F. L., Piotrowski, W. & Thastrup, Ole, 1985, In: British Journal of Pharmacology. 85, 3, p. 705-12 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The calcium mobilizing tumor promoting agent, thapsigargin elevates the platelet cytoplasmic free calcium concentration to a higher steady state level. A possible mechanism of action for the tumor promotion

    Thastrup, Ole, Foder, B. & Scharff, O., 1987, In: Biochemical and Biophysical Research Communications. 142, 3, p. 654-60 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The inflammatory and tumor-promoting sesquiterpene lactone, thapsigargin, activates platelets by selective mobilization of calcium as shown by protein phosphorylations

    Thastrup, Ole, Linnebjerg, H., Bjerrum, P. J., Knudsen, J. B. & Christensen, Søren Brøgger, 1987, In: BBA General Subjects. 927, 1, p. 65-73 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 343169660