Ole Thastrup

Ole Thastrup

Emeritus

  • Administration and Operations

    Jagtvej 160

    2100 København Ø

    Mobile: +4522115399

  1. 2018
  2. Published

    Characterization of genetic intratumor heterogeneity in colorectal cancer and matching patient-derived spheroid cultures

    Árnadóttir, S. S., Jeppesen, M., Lamy, P., Bramsen, J. B., Nordentoft, I., Knudsen, M., Vang, S., Madsen, M. R., Thastrup, Ole, Thastrup, J. & L Andersen, C., Jan 2018, In: Molecular Oncology. 12, p. 132-147

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2017
  4. Published

    Short-term spheroid culture of primary colorectal cancer cells as an in vitro model for personalizing cancer medicine

    Jeppesen, M., Hagel, G., Glenthoj, A., Vainer, B., Ibsen, Per Holger, Harling, H., Thastrup, Ole, Jørgensen, Lars Nannestad & Thastrup, J., 2017, In: PLOS ONE. 12, 9, 19 p., e0183074.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2011
  6. Published

    Identifying a compound modifying a cellular response, comprises attaching cells having a reporter system onto solid supports, releasing a library member, screening and identifying target cells

    Hagel, G., Thastrup, Ole, Meldal, Morten Peter, Norrild, J. C., Hentzer, M., Norrild, J. & Diness, Frederik, 29 Dec 2011, IPC No. G01N 35/ 00 A N, Patent No. US2011319274, Priority date 25 May 2005, Priority No. WO2005DK00348

    Research output: Patent

  7. Chemical synthesis on SU-8

    Qvortrup, K., Taveras, K., Thastrup, Ole & Nielsen, T., 2011, In: Chemical Communications. 47, 4, p. 1309-11 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2004
  9. Changes in intracellular cAMP reported by a Redistribution assay using a cAMP-dependent protein kinase-green fluorescent protein chimera

    Almholt, K., Tullin, S., Skyggebjerg, O., Scudder, K., Thastrup, Ole & Terry, R., 2004, In: Cellular Signalling. 16, 8, p. 907-20 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Functional identification and monitoring of individual alpha and beta cells in cultured mouse islets of Langerhans

    Hjortoe, G. M., Hagel, G. M., Terry, B. R., Thastrup, Ole & Arkhammar, P. O. G., 2004, In: Acta Diabetologica. 41, 4, p. 185-93 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2001
  12. Excitation wave propagation as a possible mechanism for signal transmission in pancreatic islets of Langerhans

    Aslanidi, O. V., Mornev, O. A., Skyggebjerg, O., Arkhammar, P., Thastrup, Ole, Sørensen, M. P., Christiansen, P. L., Conradsen, K. & Scott, A. C., 2001, In: Biophysical Journal. 80, 3, p. 1195-209 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2000
  14. Exclusion of known protease-activated receptors in factor VIIa-induced signal transduction

    Petersen, L. C., Thastrup, Ole, Hagel, G., Sørensen, B. B., Freskgård, P. O., Rao, L. V. & Ezban, M., 2000, In: Thrombosis and Haemostasis. 83, 4, p. 571-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Separation of the glucose-stimulated cytoplasmic and mitochondrial NAD(P)H responses in pancreatic islet beta cells

    Patterson, G. H., Knobel, S. M., Arkhammar, P., Thastrup, Ole & Piston, D. W., 2000, In: Proceedings of the National Academy of Sciences of the United States of America. 97, 10, p. 5203-7 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 1999
  17. Simultaneous visualization of the translocation of protein kinase Calpha-green fluorescent protein hybrids and intracellular calcium concentrations

    Almholt, K., Arkhammar, P. O., Thastrup, Ole & Tullin, S., 1999, In: Biochemical Journal. 337 ( Pt 2), p. 211-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. 1998
  19. Signal transduction via the mitogen-activated protein kinase pathway induced by binding of coagulation factor VIIa to tissue factor

    Poulsen, L. K., Jacobsen, N., Sørensen, B. B., Bergenhem, N. C., Kelly, J. D., Foster, D. C., Thastrup, Ole, Ezban, M. & Petersen, L. C., 1998, In: Journal of Biological Chemistry. 273, 11, p. 6228-32 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 1996
  21. Flow injection microscopy: a novel tool for the study of cellular response and drug discovery

    Ruzicka, J., Baxter, P. J., Thastrup, Ole & Scudder, K., 1996, In: Analyst. 121, 7, p. 945-50 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 1995
  23. Published

    Structure-activity relationships of analogues of thapsigargin modified at O-11 and O-12

    Nielsen, S. F., Thastrup, Ole, Pedersen, R., Olsen, C. E. & Christensen, Søren Brøgger, 1995, In: Journal of Medicinal Chemistry. 38, 2, p. 272-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 1994
  25. Published

    Characteristics of stably expressed human dopamine D1a and D1b receptors: atypical behavior of the dopamine D1b receptor

    Pedersen, U. B., Norby, B., Jensen, Anders A., Schiødt, M., Hansen, A., Suhr-Jessen, P., Scheideler, M., Thastrup, Ole & Andersen, P. H., 1994, In: European Journal of Pharmacology. 267, 1, p. 85-93 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Thapsigargin: a novel molecular probe for studying intracellular calcium release and storage

    Thastrup, Ole, Dawson, A. P., Scharff, O., Foder, B., Cullen, P. J., Drøbak, B. K., Bjerrum, P. J., Christensen, Søren Brøgger & Hanley, M. R., 1994, In: Agents and Actions. 43, 3-4, p. 187-93 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 1993
  28. Published

    Structure-activity relationships of thapsigargin

    Nielsen, S. F., Andersen, A., Olsen, C. E., Treimann, M., Thastrup, Ole & Christensen, Søren Brøgger, 1 Dec 1993, In: Planta Medica. 59, 7 SUPPL., p. A678-A679

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. 1992
  30. Published

    Biochemical and ultrastructural studies suggest that the effects of thapsigargin on human platelets are mediated by changes in intracellular calcium but not by intracellular histamine

    Saxena, S. P., McNicol, A., Becker, A. B., Brandes, L. J., Thastrup, Ole & Gerrard, J. M., 1992, In: Thrombosis and Haemostasis. 68, 6, p. 714-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. In situ imaging of agonist-sensitive calcium pools in AR4-2J pancreatoma cells. Evidence for an agonist- and inositol 1,4,5-trisphosphate-sensitive calcium pool in or closely associated with the nuclear envelope

    Glennon, M. C., Bird, G. S., Takemura, H., Thastrup, Ole, Leslie, B. A. & Putney, J. W., 1992, In: Journal of Biological Chemistry. 267, 35, p. 25568-75 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Mechanisms of activated Ca2+ entry in the rat pancreatoma cell line, AR4-2J

    Bird, G. S., Takemura, H., Thastrup, Ole, Putney, J. W. & Menniti, F. S., 1992, In: Cell Calcium. 13, 1, p. 49-58 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    On the botanical distribution of chiral forms of gossypol

    Jaroszewski, J. W., Strøm-Hansen, T., Hansen, S. H., Thastrup, Ole & Kofod, H., 1992, In: Planta Medica. 58, 5, p. 454-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    The molluscicidal activity of coumarins from Ethulia conyzoides and of dicumarol

    Kady, M. M., Brimer, L., Furu, Peter, Lemmich, E., Nielsen, H. M., Thiilborg, S. T., Thastrup, Ole & Christensen, Søren Brøgger, 1992, In: Planta Medica. 58, 4, p. 334-7 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. 1991
  36. Demonstration of two forms of calcium pumps by thapsigargin inhibition and radioimmunoblotting in platelet membrane vesicles

    Papp, B., Enyedi, A., Kovács, T., Sarkadi, B., Wuytack, F., Thastrup, Ole, Gárdos, G., Bredoux, R., Levy-Toledano, S. & Enouf, J., 1991, In: Journal of Biological Chemistry. 266, 22, p. 14593-6 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Mobilization of calcium by inositol trisphosphates from permeabilized rat parotid acinar cells. Evidence for translocation of calcium from uptake to release sites within the inositol 1,4,5-trisphosphate- and thapsigargin-sensitive calcium pool

    Menniti, F. S., Bird, G. S., Takemura, H., Thastrup, Ole, Potter, B. V. & Putney, J. W., 1991, In: Journal of Biological Chemistry. 266, 21, p. 13646-53 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Role of inositol (1,4,5)trisphosphate in epidermal growth factor-induced Ca2+ signaling in A431 cells

    Hughes, A. R., Bird, G. S., Obie, J. F., Thastrup, Ole & Putney, J. W., 1991, In: Molecular Pharmacology. 40, 2, p. 254-62 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Stimulatory effect of thapsigargin, a non-TPA-type tumor promoter, on arachidonic acid metabolism in the murine keratinocyte line HEL30 and on epidermal cell proliferation in vivo as compared to the effects of phorbol ester TPA

    Marks, F., Hanke, B., Thastrup, Ole & Fürstenberger, G., 1991, In: Carcinogenesis. 12, 8, p. 1491-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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