Trine Meldgaard Lund
Associate Professor
Translational and Clinical Pharmacology
Jagtvej 160
2100 København Ø
- 2024
- Published
Dose safety and pharmacodynamics of subcutaneous bupivacaine in a novel extended-release microparticle formulation: A phase 1, dose-ascending study in male volunteers
Jensen, E. K., Bøgevig, S., Balchen, T., Springborg, A. H., Royal, M. A., Storgaard, Ida Klitzing, Lund, Trine Meldgaard, Møller, Kirsten & Werner, M. U., 2024, In: Basic & clinical pharmacology & toxicology. 134, 5, p. 657-675Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of Multi-Frequency Bioelectrical Impedance Analysis against Dual-Energy X-ray Absorptiometry for Estimation of Low Muscle Mass in Older Hospitalized Patients
Nielsen, R. L., Andersen, A. L., Kallemose, T., Damgaard, Morten, Bornæs, O., Juul-Larsen, H. G., Strejby Christensen, L. W., Jawad, B. N., Andersen, Ove, Rasmussen, H. H., Munk, T., Lund, Trine Meldgaard & Houlind, Morten Baltzer, 2024, In: Journal of Clinical Medicine. 13, 1, 15 p., 196.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Population pharmacokinetic-pharmacodynamic model of subcutaneous bupivacaine in a novel extended-release microparticle formulation
Storgaard, Ida Klitzing, Jensen, E. K., Bøgevig, S., Balchen, T., Springborg, A. H., Royal, M. A., Møller, Kirsten, Werner, M. U. & Lund, Trine Meldgaard, 2024, In: Basic & clinical pharmacology & toxicology. 134, 5, p. 676-685Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Performance of the 2009 CKDEPI, 2021 CKDEPI, and EKFC equations among high-risk patients in Denmark
Houlind, Morten Baltzer, Iversen, E., Curovic, V. R., Jørgensen, M. B., Andersen, A., Gustafsson, Finn, Nelson, L. M. S., Perch, Michael, Damgaard, Morten, Persson, F., Feldt-Rasmussen, Bo, Andersen, Ove, Lund, Trine Meldgaard & Hornum, Mads, 2023, In: Clinical Chemistry and Laboratory Medicine. 61, 10, p. e192-e195Research output: Contribution to journal › Letter › Research › peer-review
- Published
Appetite stimulation with cannabis-based medicine and methods for assessment of glomerular filtration in older patients with medical illness: A study protocol
Nielsen, R. L., Bornæs, O., Storgaard, I. K., Kallemose, T., Jørgensen, L. M., Jawad, B. N., Altintas, I., Juul-larsen, H. G., Tavenier, J., Durhuus, J. A., Bengaard, A. K. P., Holst, J. J., Kolko, M., Sonne, D. P., Breindahl, T., Damgaard, M., Porrini, E., Hornum, M., Andersen, O., Pedersen, M. M. & 6 others, , 2023, In: Basic & Clinical Pharmacology & Toxicology. 133, 3, p. 237-253 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Comment on Delanaye et al: Future perspectives regarding kidney function estimates and dose adjustments
Iversen, E., Hornum, Mads, Lund, Trine Meldgaard & Houlind, Morten Baltzer, 2022, In: British Journal of Clinical Pharmacology. 88, 6, p. 2998-2999Research output: Contribution to journal › Letter › Research › peer-review
- Published
Artificial neural network vs pharmacometric model for population prediction of plasma concentration in real-world data: a case study on valproic acid
Soeorg, H., Sverrisdóttir, E., Andersen, Morten, Lund, Trine Meldgaard & Sessa, Maurizio, 2022, In: Clinical Pharmacology and Therapeutics. 111, 6, p. 1278-1285Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacom-epi: A framework for integrating pharmacometric modeling into Pharmacoepidemiological research using real-world data
Soeorg, H., Sverrisdottir, E., Andersen, Morten, Lund, Trine Meldgaard & Sessa, Maurizio, 2022, In: Pharmacoepidemiology and Drug Safety. 31, S2, p. 568-569Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
The PHARMACOM-EPI framework for integrating pharmacometric modelling into pharmacoepidemiological research using real-world data: application to assess death associated with valproate
Soeorg, H., Sverrisdóttir, E., Andersen, Morten, Lund, Trine Meldgaard & Sessa, Maurizio, 2022, In: Clinical Pharmacology and Therapeutics. 111, 4, p. 840-856Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Bounded Integer Modeling of Symptom Scales Specific to Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia
Lyauk, Y. K., Jonker, D. M., Hooker, A., Lund, Trine Meldgaard & Karlsson, M. O., 2021, In: The AAPS journal. 23, 2, 14 p., 33.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Midazolam Pharmacokinetics in Obese and Non-obese Children and Adolescents
Gade, C., Sverrisdóttir, E., Dalhoff, Kim, Sonne, J., Johansen, M. Ø., Christensen, H. R., Burhenne, J., Mikus, G., Holm, Jens-Christian, Lund, Trine Meldgaard & Holst, H., 2020, In: Clinical Pharmacokinetics. 59, p. 643-654Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integrated Item Response Theory Modeling of Multiple Patient-Reported Outcomes Assessing Lower Urinary Tract Symptoms Associated with Benign Prostatic Hyperplasia
Lyauk, Y. K., Lund, Trine Meldgaard, Hooker, A. C., Karlsson, M. O. & Jonker, D. M., 2020, In: The AAPS Journal. 22, 5, 13 p., 98.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Item Response Theory Modeling of the International Prostate Symptom Score in Patients with Lower Urinary Tract Symptoms Associated with Benign Prostatic Hyperplasia
Lyauk, Y. K., Jonker, D. M., Lund, Trine Meldgaard, Hooker, A. C. & Karlsson, M. O., 2020, In: The AAPS Journal. 22, 5, 15 p., 115.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Demonstrating Contribution of Components of Fixed-Dose Drug Combinations Through Longitudinal Exposure-Response Analysis
Nøhr-Nielsen, A., Lange, Theis, Forman, Julie Lyng, Papathanasiou, T., Foster, D. J. R., Upton, R. N., Bjerrum, Ole Jannik & Lund, Trine Meldgaard, 2020, In: The AAPS Journal. 22, 2, 32.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacodynamic modelling reveals synergistic interaction between docetaxel and SCO-101 in a docetaxel-resistant triple negative breast cancer cell line
Nøhr-Nielsen, A., Bagger, Sofie Morsing, Brünner, N., Stenvang, Jan & Lund, Trine Meldgaard, 2020, In: European Journal of Pharmaceutical Sciences. 148, 10 p., 105315.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of dose-escalation schemes and drug discontinuation on weight loss outcomes with liraglutide 3.0 mg: A model-based approach
Papathanasiou, T., Strathe, A., Agersø, H., Lund, Trine Meldgaard & Overgaard, R. V., 2020, In: Diabetes, Obesity and Metabolism. 22, 6, p. 969-977 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-dose naloxone: Effects by late administration on pain and hyperalgesia following a human heat injury model. A randomized, double-blind, placebo-controlled, crossover trial with an enriched enrollment design
Springborg, A. D., Jensen, E. K., Kreilgaard, M., Petersen, M. A., Papathanasiou, T., Lund, Trine Meldgaard, Taylor, B. K. & Werner, M. U., 2020, In: PLoS ONE. 15, 11, 22 p., e0242169.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Simultaneous quantification of high-dose naloxone and naloxone-3-β-D-glucuronide in human plasma by UHPLC-MS/MS
Kongstad, Kenneth Thermann, Papathanasiou, T., Springborg, A., Lund, Trine Meldgaard, Werner, M. U. & Stærk, Dan, 2019, In: Bioanalysis. 11, 03, p. 165-173Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dose Finding in the Clinical Development of 60 US Food and Drug Administration-Approved Drugs Compared With Learning vs. Confirming Recommendations
Lyauk, Y. K., Jonker, D. M. & Lund, Trine Meldgaard, 2019, In: Clinical and Translational Science. 12, 5, p. 481-489Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Body of evidence and approaches applied in the clinical development programme of fixed-dose combinations in the European Union from 2010 to 2016
Nøhr-Nielsen, A., De Bruin, M. L., Thomsen, M., Pipper, C. B., Lange, Theis, Bjerrum, Ole Jannik & Lund, Trine Meldgaard, 2019, In: British Journal of Clinical Pharmacology. 85, 8, p. 1829-1840 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-dose naloxone, an experimental tool uncovering latent sensitisation: pharmacokinetics in humans.
Papathanasiou, T., Springborg, A., Kongstad, Kenneth Thermann, Stærk, Dan, Møller, Kirsten, Taylor, B. K., Lund, Trine Meldgaard & Werner, M. U., 2019, In: British Journal of Anaesthesia. 123, 2, p. e204-e214Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Optimizing Dose-Finding Studies for Drug Combinations Based on Exposure-Response Models
Papathanasiou, T., Strathe, A., Overgaard, R. V., Lund, Trine Meldgaard & Hooker, A. C., 29 Jul 2019, In: The AAPS Journal. 21, 5, 95.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Feasibility of Exposure-Response Analyses for Clinical Dose-Ranging Studies of Drug Combinations
Papathanasiou, T., Strathe, A., Hooker, A. C., Lund, Trine Meldgaard & Overgaard, R. V., May 2018, In: The AAPS Journal. 20, 13 p., 64.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Analysis of opioid consumption in clinical trials: a simulation based analysis of power of four approaches
Juul, R. V., Nyberg, J., Kreilgaard, M., Christrup, Lona Louring, Simonsson, U. S. H. & Lund, Trine Meldgaard, Aug 2017, In: Journal of Pharmacokinetics and Pharmacodynamics. 44, 4, p. 325-333 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantification of the Pharmacodynamic Interaction of Morphine and Gabapentin Using a Response Surface Approach
Papathanasiou, T., Juul, R. V., Gabel-Jensen, C., Kreilgaard, M., Heegaard, Anne-Marie & Lund, Trine Meldgaard, 1 Nov 2017, In: AAPS Journal. 19, 6, p. 1804–1813 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1303792
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Kroppens egne cannabinoider påvirker immunsystemet
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197
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Pharmacokinetic Metamodel of Morphine and Morphine-6-Glucuronide in Neonates and Adults
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85
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Dose Finding in the Clinical Development of 60 US Food and Drug Administration-Approved Drugs Compared With Learning vs. Confirming Recommendations
Research output: Contribution to journal › Journal article › Research › peer-review
Published