Department of Drug Design and Pharmacology

Bente Vestergaard

Professor Emerita, Professor emeritus.

Biopharmaceuticals
Jagtvej 162
2100 København Ø
- bente.vestergaard@sund.ku.dk
- https://ilf.ku.dk/
Phone: +4535336403

Member of:

I am the group leader of the BioSAXS group, dept. Drug Design and Pharmacology, University of Copenhagen, and the director of the Lundbeck Foundation Initiative on Integrative Structural Biology, BRAINSTRUC (http://www.brainstruc.ku.dk). I have focused on structural biology throughout my carreer. I was trained in macromolecular X-ray crystallography and have experience with cryo electron microscopy, atomic force microscopy and X-ray fiber diffraction. Since 2004 I have specialized in small angle X-ray scattering on proteins in solution and have established the first Scandinavian bioSAXS group at the University of Copenhagen. In my group, we focus on structural characterisation of complex pharmaceutically relevant protein solutions. We analyze heterogeneous protein systems, and particularly specialize in characterisation of fibrillating proteins. We have developed novel methods for structural analysis of fibrillating systems, applying advanced decomposition and multidisciplinary characterisation.

Primary fields of research

BioSAXS

Structural Analysis of Protein Fibrillation

Structural Biology

Teaching

National Teaching: course responsible for 'Advances in Medicinal Chemistry Research'. Lecturer and supervisor of practicals on 'Medicinal and Biostructural Chemistry'.

International Teaching: Co-organizer (together with my close colleague prof. Lise Arleth) of the Copenhagen BioSAS practial courses on biomacromolecular solution scattering. The courses aim at international young researchers (PhD, postdoc level) and is a collaboration with the group of EMBL group leader Dmitri Svergun and MAX-lab SAXS beamline (I911-4). I am returning teacher on the EMBL-Hamburg EMBO BioSAS courses, and (more recently) the ESRF Grenoble EMBO BioSAS course.

Selected publications

Published
A helical structural nucleus is the primary elongating unit of insulin amyloid fibrils
Vestergaard, Bente, Jensen, M. G., Roessle, M., Kastrup, Jette Sandholm Jensen, van de Weert, Marco, Flink, J. M., Frøkjær, Sven, Gajhede, Michael & Svergun, D. I., 2007, In: PLoS - Biology. 5, 5, p. 1089-1097
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Ionotropic glutamate-like receptor d2 binds D-serine and glycine.
Naur, P., Hansen, K. B., Kristensen, Anders Skov, Dravid, S. M., Pickering, Darryl S, Olsen, L., Vestergaard, Bente, Egebjerg, J., Gajhede, Michael, Traynelis, S. F. & Kastrup, Jette Sandholm Jensen, 2007, In: Proceedings of the National Academy of Science of the United States of America. 104, 35, p. 14116-14121
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Small angle X-ray scattering study of calreticulin reveals conformational plasticity
Toft, K. N., Larsen, N., Jørgensen, Flemming Steen, Højrup, P., Houen, G. & Vestergaard, Bente, 2008, In: BBA General Subjects. 1784, 9, p. 1265-1270
Research output: Contribution to journal › Journal article › Research › peer-review
Published
High-throughput small angle X-ray scattering from proteins in solution using a microfluidic front-end
Toft, K. N., Vestergaard, Bente, Nielsen, S. S., Snakenborg, D., Jeppesen, Mads Gravers, Jacobsen, J. K., Arleth, Lise & Kutter, J. P., 2008, In: Analytical Chemistry. 80, 10, p. 3648-3654 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency
Beich-Frandsen, M., Pickering, Darryl S, Mirza, Osman Asghar, Johansen, Tommy Nørskov, Greenwood, J., Vestergaard, Bente, Schousboe, Arne, Gajhede, Michael, Liljefors, T. & Kastrup, Jette Sandholm Jensen, 2008, In: Journal of Medicinal Chemistry. 51, 5, p. 1459-63
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Application of Bayesian analysis to indirect fourier transformation in small-angle scattering
Vestergaard, Bente & Hansen, S. L., 2006, In: Journal of Applied Crystallography. 39, p. 797-804 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Small angle X-ray studies reveal that Aspergillus niger glucoamylase has a defined extended conformation and can form dimers in solution
Jørgensen, A. D., Nøhr, J., Kastrup, Jette Sandholm Jensen, Gajhede, Michael, Sigurskjold, B. W., Sauer, J., Svergun, D. I., Svensson, B. & Vestergaard, Bente, 2008, In: Journal of Biological Chemistry. 283, 21, p. 14772-14780
Research output: Contribution to journal › Journal article › Research › peer-review
Published
A new small-angle X-ray scattering set-up on the crystallography beamline I711 at MAX-lab
Knaapila, M., Svensson, C., Barauskas, J., Zackrisson, M., Nielsen, S. S., Toft, K. N., Vestergaard, Bente, Arleth, Lise, Olsson, U., Pedersen, J. S. & Cerenius, Y., 2009, In: Journal of Synchrotron Radiation. 16, 4, p. 498-504 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
BioXTAS RAW, a software program for high-throughput automated small-angle X-ray scattering data reduction and preliminary analysis
Nielsen, S. S., Toft, K. N., Snakenborg, D., Jeppesen, Mads Gravers, Jacobsen, J. K., Vestergaard, Bente, Kutter, J. P. & Arleth, Lise, 2009, In: Journal of Applied Crystallography. 42, 5, p. 959-964 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Synergies within the natural sciences at the University of Copenhagen: an interfaculty evaluation of barriers and opportunities to improve the quality of infrastructure, research and education
Krogsgaard-Larsen, Povl, Møller, Birger Lindberg, Larsen, Erik Hviid, Vestergaard, Bente, Lunde, C., Stæhr, P. A. & Andersen, J. (ed.), 2009, Faculty of Life Sciences: Museum Tusculanum. 43 p.
Research output: Book/Report › Book › Research
Published
Methods for structural characterization of prefibrillar intermediates and amyloid fibrils
Langkilde, Annette Eva & Vestergaard, Bente, 2009, In: FEBS Letters. 583, 16, p. 2600-2609
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Extensive small-angle X-ray scattering studies of blood coagulation factor VIIa reveal interdomain flexibility
Mosbæk, C. R., Nolan, D., Persson, E., Svergun, D. I., Bukrinsky, J. T. & Vestergaard, Bente, 2010, In: Biochemistry. 49, 45, p. 9739-9745
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Formation mechanism of insulin fibrils and structural aspects of the insulin fibrillation process
Jensen, M. G., Frøkjær, Sven & Vestergaard, Bente, 2009, In: Current Protein and Peptide Science. 10, 5, p. 509-528
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Self-association of long-acting insulin analogues studied by size exclusion chromatography coupled to multi-angle light scattering
Jensen, M. H., Wahlund, P., Jacobsen, J. K., Vestergaard, Bente, van de Weert, Marco & Havelund, S., 2011, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 879, 28, p. 2945-2951
Research output: Contribution to journal › Journal article › Research › peer-review
Bacterial polypeptide release factor RF2 is structurally distinct from eukaryotic eRF1
Vestergaard, Bente, Van, L. B., Andersen, G. R., Nyborg, J. & Kjeldgaard, M., 2001, In: Molecular Cell. 8, p. 1375-1382 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Recognition by tryptophanyl-tRNA synthetases of discriminator base on tRNATrp from three biological domains
Guo, Q., Vestergaard, Bente, Costa, Degres, Wong, Grosjean, Zhu, Wong & Xue, 2002, In: Journal of Biological Chemistry. 277, p. 14343-14349 6 p.
Research output: Contribution to journal › Journal article › Research › peer-review
A cryo-electron microscopic study of ribosome-bound termination factor RF2
Rawat, Zavialov, A., Sengupta, Valle, Grasucci, Linde, Vestergaard, Bente, Ehrenberg, M. & Frank, J., 2003, In: Nature. 421, p. 87-90 4 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Structure of the E. coli ribosomal termination complex with release factor 2
Klaholz, B., Pape, T., Zavialov, A., Myasnikov, Orlova, Vestergaard, Bente, Ehrenberg, M. & van Heel, M., 2003, In: Nature. 421, p. 90-94 5 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Crystal structure of the kainate receptor GluR5 ligand-binding core in complex with (S)-glutamate
Naur, P., Vestergaard, Bente, Skov, L., Egebjerg, J., Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 2005, In: FEBS Letters. 579, p. 1154-60
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Diverse bacterial genomes encode an operon of two genes, one of which is a unusual class-I release factor that potentially recognizes atypical mRNA signals other than normal stop codons
Baranov, P., Vestergaard, Bente, Hamelryck, Thomas Wim, Gesteland, Nyborg, J. & Atking, J., 2006, In: Biology Direct. 13, p. 1-28 28 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage
Bach, Anders, Clausen, B. H., Møller, M., Vestergaard, Bente, Chi, C. N., Round, A., Sørensen, P. L., Nissen, K. B., Kastrup, Jette Sandholm Jensen, Gajhede, Michael, Jemth, P., Kristensen, Anders Skov, Lundström, P., Lambertsen, K. L. & Strømgaard, Kristian, 28 Feb 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 9, p. 3317-3322
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Structural characterization of prefibrillar intermediates and amyloid fibrils by small-angle X-ray scattering
Langkilde, Annette Eva & Vestergaard, Bente, 2012, Amyloid proteins: methods and protocols. Sigurdsson, E. M., Calero, M. & Gasset, M. (eds.). 2 ed. New York: Springer Science+Business Media, Vol. 849. p. 137-155 18 p. (Methods in Molecular Biology, Vol. 849).
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
Published
Small angle X-ray scattering-based elucidation of the self-association mechanism of human insulin analogue lys(B29)(N(e)¿-carboxyheptadecanoyl) des(B30)
Jensen, M. H., Wahlund, P., Toft, K. N., Jacobsen, J. K., Steensgaard, D. B., van de Weert, Marco, Havelund, S. & Vestergaard, Bente, 15 Jan 2013, In: Biochemistry. 52, 2, p. 282-94 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Large-scale polymorphism and auto-catalytic effect in insulin fibrillogenesis
Foderà, Vito, van de Weert, Marco & Vestergaard, Bente, 2010, In: Soft Matter. 6, 18, p. 4413-4419
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The SAXS Solution Structure of RF1 Differs from Its Crystal Structure and Is Similar to Its Ribosome Bound Cryo-EM Structure
Vestergaard, Bente, Sanyal, S., Roessle, M., Mora, L., Buckingham, R., Kastrup, Jette Sandholm Jensen, Gajhede, Michael, Svergun, D. I. & Ehrenberg, M., 2005, In: Molecular Cell. 20, p. 929-938
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Unlocked Concanavalin A Forms Amyloid-like Fibrils from Coagulation of Long-lived “Crinkled” Intermediates
Vetri, V., Leone, M., Morozova-Roche, L. A., Vestergaard, Bente & Foderà, Vito, 2013, In: PLoS ONE. 8, 7, 11 p., e68912.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Structural Investigations of on-pathway Oligomers of α-Synuclein
Pedersen, M. N., Horvath, I., Weise, C. F., Foderà, Vito, Wittung-Stafshede, P., Wolf-Watz, M., Toft, K. N. & Vestergaard, Bente, 31 May 2012.
Research output: Contribution to conference › Poster › Research
Published
High concentration formulation studies of an IgG2 antibody using small angle X-ray scattering
Mosbæk, C. R., Konarev, P., Svergun, D. I., Rischel, C. & Vestergaard, Bente, 2012, In: Pharmaceutical Research. 29, 8, p. 2225-2235
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Structural model and trans-interaction of the entire ectodomain of the olfactory cell adhesion molecule
Kulahin, N., Kristensen, O., Rasmussen, K. K., Olsen, L., Rydberg, P., Vestergaard, Bente, Kastrup, Jette Sandholm Jensen, Berezin, V., Bock, E., Walmod, P. S. & Gajhede, Michael, 9 Feb 2011, In: Structure. 19, 2, p. 203-211
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Automated microfluidic sample-preparation platform for high-throughput structural investigation of proteins by small-angle X-ray scattering
Lafleur, J., Snakenborg, D., Nielsen, S. S., Møller, M., Toft, K. N., Menzel, A., Jacobsen, J. K., Vestergaard, Bente, Arleth, Lise & Kutter, J. P., 2011, In: Journal of Applied Crystallography. 44, p. 1090-1099 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Tyr702 is an important determinant of agonist binding and domain closure of the ligand-binding core of GluR2
Frandsen, A., Pickering, Darryl S, Vestergaard, Bente, Kasper, C., Nielsen, B. B., Greenwood, J. R., Campiani, G., Fattorusso, C., Gajhede, Michael, Schousboe, Arne & Kastrup, Jette Sandholm Jensen, 2005, In: Molecular Pharmacology. 67, 3, p. 703-13 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Low-resolution structure of a vesicle disrupting a-synuclein oligomer that accumulates during fibrillation
Giehm, L., Svergun, D. I., Otzen, D. E. & Vestergaard, Bente, 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 8, p. 3246-3251
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Time-resolved SAXS measurements facilitated by online HPLC buffer exchange
Jensen, M. H., Toft, K. N., David, G., Havelund, S., Pérez, J. & Vestergaard, Bente, 2010, In: Journal of Synchrotron Radiation. 17, 6, p. 769-773
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Gennembrud i forståelsen af insulinfibrillering
Jensen, M. G., Vestergaard, Bente, Frøkjær, Sven, Gajhede, Michael, Flink, J. M., van de Weert, Marco, Kastrup, Jette Sandholm Jensen & Svergun, D. I., 2007, In: Lægemiddelforskning. p. 10-11
Research output: Contribution to journal › Journal article › Communication
Published
Kimen til de farlige fibriller
Jensen, M. G. & Vestergaard, Bente, 2007, In: Aktuel Naturvidenskab. 6, p. 12-15
Research output: Contribution to journal › Journal article › Communication
Published
Noninvasive Structural Analysis of Intermediate Species During Fibrillation: An Application of Small-Angle X-Ray Scattering
Langkilde, Annette Eva, Herranz-Trillo, F., Bernadó, P. & Vestergaard, Bente, 8 Jun 2018, Amyloid Proteins: methods and protocols. Sigurdsson, E., Calero, M. & Gasset, M. (eds.). Humana Press, Vol. 1779. p. 209-239 31 p. (Methods in Molecular Biology).
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
Published
Structural Analysis of Multi-component Amyloid Systems by Chemometric SAXS Data Decomposition
Trillo, I. F. H., Jensen, M. G., van Maarschalkerweerd, A., Tauler, R., Vestergaard, Bente & Bernadó, P., 3 Jan 2017, In: Structure. 25, 1, p. 5–15 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
SAS-Based Studies of Protein Fibrillation
Marasini, C. & Vestergaard, Bente, 2017, Biological Small Angle Scattering: Techniques, Strategies and Tips. Springer Science+Business Media, Vol. 1009. p. 149-165 17 p. (Advances in Experimental Medicine and Biology).
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
Published
Sucrose modulates insulin amyloid-like fibril formation: effect on the aggregation mechanism and fibril morphology
Marasini, C., Foderà, Vito & Vestergaard, Bente, 2017, In: RSC Advances. 7, p. 10487-10493
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Trifluoroethanol modulates α-synuclein amyloid-like aggregate formation, stability and dissolution
Di Carlo, M. G., Vetri, V., Buscarino, G., Leone, M., Vestergaard, Bente & Foderà, Vito, Sep 2016, In: Biophysical Chemistry. 216, p. 23-30 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Analysis of biostructural changes, dynamics, and interactions - Small-angle X-ray scattering to the rescue
Vestergaard, Bente, 15 Jul 2016, In: Archives of Biochemistry and Biophysics. 602, p. 69-79 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Mechanistic study of the inhibitory activity of Geum urbanum extract against α-Synuclein fibrillation
Lobbens, E. S., Breydo, L., Pedersen, T. S., Vestergaard, Bente, Jäger, A. K., Jørgensen, Lene, Uversky, V. & van de Weert, Marco, 21 Jun 2016, In: B B A - Proteins and Proteomics. 1864, 9, p. 1160-1169 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Monoclonal Antibodies Follow Distinct Aggregation Pathways During Production-Relevant Acidic Incubation and Neutralization
Pedersen, T. S., Tian, X., Thorolfsson, M., Karkov, H. S., Rasmussen, H. B., Langkilde, Annette Eva & Vestergaard, Bente, Mar 2016, In: Pharmaceutical Research. 33, 3, p. 716-28 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Protein-protein interactions: a supra-structural phenomenon demanding trans-disciplinary biophysical approaches
Byron, O. & Vestergaard, Bente, Dec 2015, In: Current Opinion in Structural Biology. 35, p. 76-86 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Formation of covalent di-tyrosine dimers in recombinant α-synuclein
van Maarschalkerweerd, A., Pedersen, M., Peterson, H., Nilsson, M., Nguyen, T., Skamris, T., Rand, Kasper Dyrberg, Vetri, V., Langkilde, Annette Eva & Vestergaard, Bente, 19 Oct 2015, In: Intrinsically Disordered Proteins. 3, 1, p. 1-12 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Cholesterol facilitates interactions between α-synuclein oligomers and charge-neutral membranes
van Maarschalkerweerd, A., Vetri, V. & Vestergaard, Bente, 14 Sep 2015, In: FEBS Letters. 589, 19 Pt B, p. 2661-7 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Structure of dimeric and tetrameric complexes of the BAR domain protein PICK1 determined by small-angle X-Ray scattering
Karlsen, M. L., Thorsen, T. S., Johner, N., Ammendrup-Johnsen, I., Erlendsson, Simon, Tian, X., Simonsen, J. B., Hoiberg-Nielsen, R., Christensen, N. M., Khelashvili, G., Streicher, W., Teilum, Kaare, Vestergaard, Bente, Weinstein, H., Gether, Ulrik, Arleth, Lise & Madsen, Kenneth Lindegaard, 7 Jul 2015, In: Structure. 23, 7, p. 1258-1270 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
The architecture of amyloid-like peptide fibrils revealed by X-ray scattering, diffraction and electron microscopy
Langkilde, Annette Eva, Morris, K. L., Serpell, L. C., Svergun, D. I. & Vestergaard, Bente, Apr 2015, In: Acta crystallographica. Section D, Biological crystallography. 71, Pt 4, p. 882-95 14 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
In-depth analysis of subclass-specific conformational preferences of IgG antibodies
Tian, X., Vestergaard, Bente, Thorolfsson, M., Yang, Z., Rasmussen, H. B. & Langkilde, Annette Eva, 1 Jan 2015, In: IUCrJ. 2, 1, p. 9-18 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Considerably Unfolded Transthyretin Monomers Preceed and Exchange with Dynamically Structured Amyloid Protofibrils
Groenning, M., Campos, R. I., Hirschberg, D., Hammarström, P. & Vestergaard, Bente, 2015, In: Scientific Reports. 5, p. 1-18 18 p., 11443.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Direct Correlation Between Ligand-Induced α-Synuclein Oligomers and Amyloid-like Fibril Growth
Pedersen, M. N., Foderà, Vito, Horvath, I., van Maarschalkerweerd, A., Nørgaard Toft, K., Weise, C., Almqvist, F., Wolf-Watz, M., Wittung-Stafshede, P. & Vestergaard, Bente, 2015, In: Scientific Reports. 5, p. 1-12 12 p., 10422.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Protein/lipid coaggregates are formed during α-synuclein-induced disruption of lipid bilayers
van Maarschalkerweerd, A., Vetri, V., Langkilde, Annette Eva, Foderà, Vito & Vestergaard, Bente, 13 Oct 2014, In: Biomacromolecules. 15, 10, p. 3643-54 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Observation of the Early Structural Changes Leading to the Formation of Protein Superstructures
Foderà, Vito, Vetri, V., Wind, T. S., Noppe, W., Cornett, Claus, Donald, A. M., Morozova-Roche, L. A. & Vestergaard, Bente, 18 Sep 2014, In: Journal of Physical Chemistry Letters. 5, 18, p. 3254-3258 5 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Small-Angle X-ray Scattering Screening Complements Conventional Biophysical Analysis: Comparative Structural and Biophysical Analysis of Monoclonal Antibodies IgG1, IgG2, and IgG4
Tian, X., Langkilde, Annette Eva, Thorolfsson, M., Rasmussen, H. B. & Vestergaard, Bente, Jun 2014, In: Journal of Pharmaceutical Sciences. 103, 6, p. 1701-10 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
In situ microfluidic dialysis for biological small-angle X-ray scattering.
Vestergaard, Bente & Skou, M., 2014, In: Journal of Applied Crystallography. 47, p. 1355-1366 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Small Angle X-Ray Scattering Studies of Mitochondrial Glutaminase C Reveal Extended Flexible Regions, and Link Oligomeric State with Enzyme Activity
Møller, M., Nielsen, S. S., Ramachandran, S., Li, Y., Tria, G., Streicher, W., Petoukhov, M. V., Cerione, R. A., Gillilan, R. E. & Vestergaard, Bente, 30 Sep 2013, In: P L o S One. 8, 9, e74783.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Wildtype and A30P mutant alpha-synuclein form different fibril structures
Nielsen, S. B., Macchi, F., Raccosta , S., Langkilde, Annette Eva, Giehm, L., Kyrsting, A. H., Svane, A. S. P., Manno, M., Christiansen, G., Nielsen, N. C., Oddershede, L. B., Vestergaard, Bente & Otzen, D., 2013, In: PLOS ONE. 8, 7, e67713.
Research output: Contribution to journal › Journal article › Research › peer-review

ID: 1305569

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1511 downloads
Wildtype and A30P mutant alpha-synuclein form different fibril structures
Research output: Contribution to journal › Journal article › Research › peer-review
Published
1120 downloads
Small Angle X-Ray Scattering Studies of Mitochondrial Glutaminase C Reveal Extended Flexible Regions, and Link Oligomeric State with Enzyme Activity
Research output: Contribution to journal › Journal article › Research › peer-review
Published
270 downloads
Size-exclusion chromatography small-angle X-ray scattering of water soluble proteins on a laboratory instrument
Research output: Contribution to journal › Journal article › Research › peer-review
Published