Trond Ulven
Professor
The research activities in our group are within medicinal chemistry, drug discovery, and development of tools and synthetic method for these areas. We are especially interested in G protein-coupled 7-transmembrane receptors, best known as GPCRs. We have especially focused on the free fatty acid receptors, a group of receptors that has great potential as drug targets. We are also interested in various other targets within inflammation and metabolic diseases, including chemokine receptors and the energy level monitoring kinase AMPK. Our medicinal chemistry projects revolved design - synthesis - evaluation to map structure-activity relationships and efficiently identify compounds with desired properties. Much of our effort go into synthesis and we continuously aim at developing simpler and more efficient, as well as greener, synthetic methods that can be useful to medicinal chemistry.
ID: 187375453
Most downloads
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291
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Discovery of a Potent Thiazolidine Free Fatty Acid Receptor 2 Agonist with Favorable Pharmacokinetic Properties
Research output: Contribution to journal › Journal article › Research › peer-review
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131
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Butyrate ameliorates allergic airway inflammation by limiting eosinophil trafficking and survival
Research output: Contribution to journal › Journal article › Research › peer-review
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120
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Dihydropyridine Fluorophores Allow for Specific Detection of Human Antibodies in Serum
Research output: Contribution to journal › Journal article › Research › peer-review
Published