Nane Griem-Krey
Guest Researcher
My research is focused on the elucidation of the in vivo mechanism-of-action of GHB ligands. GHB (g-hydroxybutyric acid) is a proposed neuromodulator, but it is also known as the drug of abuse Fantasy and the clinically prescribed drug Xyrem for the treatment of narcolepsy. Pre-clinical studies showed a neuroprotective effect of GHB ligands in acute brain injury. Therefore, my project is focussing studying the neuroprotective potential of GHB ligands by employing the model of photothrombotic stroke.
ID: 203150894
Most downloads
-
164
downloads
Synthesis and Pharmacological Evaluation of [C-11]4-Methoxy-N-[2-(thiophen-2-yl) imidazo[1,2-a] pyridin-3-yl]benzamide as a Brain Penetrant PET Ligand Selective for the delta-Subunit-Containing gamma-Aminobutyric Acid Type A Receptors
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
29
downloads
The CaMKIIα hub ligand Ph-HTBA promotes neuroprotection after focal ischemic stroke by a distinct molecular interaction
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
22
downloads
CaMKIIα as a Promising Drug Target for Ischemic Grey Matter
Research output: Contribution to journal › Review › Research › peer-review
Published