Dan Stærk
Head of Department, Visiting professor
Administration and Operations
Jagtvej 160
2100 København Ø
Biopharmaceuticals
Jagtvej 162
2100 København Ø
- Published
Identification of α-glucosidase inhibitors in apple peel - a chemometric approach
Schmidt, J. S., Daykin, C. A. & Stærk, Dan, 2012. 1 p.Research output: Contribution to conference › Poster › Research
- Published
Assessment of constituents in Allium by multivariate data analysis, high-resolution α-glucosidase inhibition assay and HPLC-SPE-NMR
Schmidt, J. S., Nyberg, N. & Stærk, Dan, 2014, In: Food Chemistry. 161, p. 192-198 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hyaluronidase, phospholipase A2 and protease inhibitory activity of plants used in traditional treatment of snakebite-induced tissue necrosis in Mali, DR Congo and South Africa
Schmidt, M. M., Nielsen, L. H., Søgaard, S. V., Stærk, Dan, Rønsted, Nina, Diallo, D., Kusamba Zacharie, C., van Staden, J. & Jäger, A., 2014, In: Journal of Ethnopharmacology. 157, p. 171-180 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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African plants for inhibition of necrotic enzymes from snake venom
Schmidt, M. M., Nielsen, L., Søgaard, S., Stærk, Dan, Rønsted, Nina, Diallo, D., Kusamba Zacharie, C., Van Staden, J. & Jäger, A. K., 2014.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Investigation of skin permeation, ex vivo inhibition of venom-induced tissue destruction, and wound healing of African plants used against snakebites
Schmidt, M. M., Stærk, Dan, Nielsen, Hanne Mørck, Brandner, J. M., Diallo, D., Kusamba Zacharie, C., Van Staden, J. & Jäger, A., 2015, In: Journal of Ethnopharmacology. 165, p. 1-8Research output: Contribution to journal › Journal article › Research › peer-review
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Biodiscoveries within the Australian plant genus Eremophila based on international and interdisciplinary collaboration: results and perspectives on outstanding ethical dilemmas
Semple, S., Stærk, Dan, Buirchell, B., Fowler, R., Gericke, Oliver, Kjaerulff, Louise, Zhao, Yong, Pedersen, H. A., Petersen, M. J., Rasmussen, L. F., Bredahl, E. K., Pedersen, Gustav Blichfeldt, McNair, Laura M., Ndi, C., Hansen, N. L., Heskes, A., Bayly, M., Loland, Claus Juul, Heinz, Nanna & Møller, Birger Lindberg, 2022, In: Plant Journal. 111, 4, p. 936-953 15866.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of residual water and microwave heating on half-lifes of reagents and reactive intermediates in peptide synthesis
Shelton, A. P. T., Pedersen, S. L., Stærk, Dan & Jensen, Knud Jørgen, 2012, In: Chemistry: A European Journal. 18, 29, p. 9024-9031 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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High-resolution α-glucosidase inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of anti-diabetic compounds in Eremanthus crotonoides (Asteraceae)
Silva, E. L., Lobo, J., Vinther, J. M., Borges, R. M. & Stærk, Dan, Dec 2016, In: Planta Medica. 82, S 01Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Athenolide A, a new steroidal lactone from the leaves of Athenaea martiana (Solanacea) determined by means of HPLC-HRMS-SPE-NMR analysis
Silva, E. L., Almeida-Lafetá, R. C., Borges, R. M. & Stærk, Dan, Jan 2018, In: Chemistry & Biodiversity. 15, 1, 8 p., e1700455.Research output: Contribution to journal › Journal article › Research › peer-review
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Dual high-resolution inhibition profiling and HPLC-HRMS-SPE-NMR analysis for identification of α-glucosidase and radical scavenging inhibitors in Solanum americanum Mill.
Silva, E. L. E., Almeida-Lafetá, R. C., Borges, R. M. & Stærk, Dan, 2017, In: Fitoterapia. 118, p. 42-48Research output: Contribution to journal › Journal article › Research › peer-review
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Targeted natural product isolation guided by HPLC-SPE-NMR: constituents of Hubertia species
Sprogøe, K., Stærk, Dan, Jäger, A. K., Adsersen, A., Hansen, S. H., Witt, M., Landbo, A. R., Meyer, A. S. & Jaroszewski, J. W., 2007, In: Journal of Natural Products. 70, 9, p. 1472-1477Research output: Contribution to journal › Journal article › Research › peer-review
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Combining HPLC-PDA-MS-SPE-NMR with circular dichroism for complete natural product characterization in crude extracts: Levorotatory gossypol in Thespesia danis
Sprogøe, K., Stærk, Dan, Ziegler, H. L., Jensen, T. H., Holm-Møller, S. B. & Jaroszewski, J. W., 2008, In: Journal of Natural Products. 71, 4, p. 516-519Research output: Contribution to journal › Journal article › Research › peer-review
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Leishmanicidal, antiplasmodial and cytotoxic activity of indole alkaloids from Corynanthe pachyceras
Stærk, Dan, Lemmich, E., Christensen, J., Kharazmi, A., Olsen, C. E. & Jaroszewski, J. W., 2000, In: Planta Medica. 66, p. 531-536Research output: Contribution to journal › Journal article › Research › peer-review
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Isolation of a library of aromadendranes from Landolphia dulcis and its characterization using the VolSurf approach
Stærk, Dan, Skole, B., Jørgensen, Flemming Steen, Budnik, B. A., Ekpe, P. & Jaroszewski, J. W., 2004, In: Journal of Natural Products. 67, 5, p. 799-805 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Itoside A and 4-hydroxytremulacin from Dovyalis caffra and Dovyalis zeyheri
Stanstrup, Jan, Rusch, A., Agnolet, S., Rasmussen, H. B., Mølgaard, Per, Van Staden, J., Stafford, G. I. & Stærk, Dan, 2010, In: Biochemical Systematics and Ecology. 38, 3, p. 346-348 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bisbenzylisoquinoline alkaloids as markers of Atherospermataceae: tetrandrine and fangchinoline from Laureliopsis philippiana
Stanstrup, Jan, Schmidt, J. S., Rasmussen, H. B., Mølgaard, Per, Guzmán, A. & Stærk, Dan, 2010, In: Biochemical Systematics and Ecology. 38, 3, p. 450-453 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of Fungal Plasma Membrane H+-ATPase Inhibitors in Lecaniodiscus cupanioides by HPLC-HRMS-SPE-NMR
Straadt, I. K., Kongstad, Kenneth Thermann & Stærk, Dan, 2015.Research output: Contribution to conference › Poster › Research
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NMR-spectroscopic studies, and pharmacological evaluation of alkaloids from some medicinal plants
Stærk, Dan, 2000, Royal Danish school of Pharmacy.Research output: Book/Report › Ph.D. thesis › Research
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Selagoline, a new alkaloid from Huperzia selago
Stærk, Dan, Larsen, J., Larsen, L. A., Olafsdottir, E. S., Witt, M. & Jaroszewski, J. W., 2004, In: Natural Product Research. 18, p. 197-203Research output: Contribution to journal › Journal article › Research › peer-review
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Accelerated dereplication of crude extracts using HPLC-PDA-MS-SPE-NMR
Stærk, Dan, Kesting, J. R., Sairafianpour, M., Witt, M., Asili, J., Emami, S. A. & Jaroszewski, J. W., 2009, In: Phytochemistry. 70, 8, p. 1055-1061 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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HPLC-NMR techniques for plant extract analysis
Stærk, Dan, Lambert, M. & Jaroszewski, J. W., 2006, Medicinal Plant Biotechnology. From Basic Research to Applications. Kayser, O. & Quax, W. J. (eds.). Weinheim: Wiley-VCH, p. 29-48Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Moderne naturstofkemi: effektiv analyse af naturens stofbiblioteker
Stærk, Dan, Lemmich, E., Franzyk, Henrik, Lemmich, J. & Jaroszewski, J. W., 2000, In: Lægemiddelforskning. p. 6-7Research output: Contribution to journal › Journal article › Communication
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New bisbenzylisoquinoline alkaloid from Laureliopsis philippiana
Stærk, Dan, Thi, L. P., Rasmussen, H. B., Guzmán, A. & Mølgaard, Per, 2009, In: Fitoterapia. 80, 2, p. 112-114 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Fremtidens funktionelle fødevarer - et vigtigt middel i kampen mod livsstilssygdomme
Stærk, Dan, 2012, Profil/Fødevarer & Sundhed. København: Københavns Universitet, Kommunikation, p. 18-19 2 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
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Hyphenation of HPLC, SPE and NMR for analysis of complex mixtures
Stærk, Dan, 2009.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Jagten på bioaktive naturstoffer: Sammenkoblet HPLC-PDA-HRMS-SPE-NMR til hurtig identifikation af bioaktive naturstoffer i komplekse blandinger
Stærk, Dan, 2021, In: Dansk Kemi. 102, 4, p. 40-44Research output: Contribution to journal › Contribution to newspaper - Feature article › Communication
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Noter til M25-1 spektroskopi
Stærk, Dan & Jaroszewski, J. W., 2007, København: Københavns Universitet, Det Farmaceutiske Fakultet, Institut for Medicinalkemi. 49 p.Research output: Book/Report › Compendium/lecture notes › Education
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In vitro cytotoxic activity of phenanthroindolizidine alkaloids from Cynanchum vincetoxicum and Tylophora tanakae against drug-sensitive and multidrug-resistant cancer cells
Stærk, Dan, Lykkeberg, A. K., Christensen, J., Budnik, B. A., Abe, F. & Jaroszewski, J. W., 2002, In: Journal of Natural Products. 65, p. 1299-1302Research output: Contribution to journal › Journal article › Research › peer-review
- Published
HPLC-NMR Techniques for Plant Extract Analysis
Stærk, Dan, Lambert, M. & Jaroszewski, J. W., 20 Mar 2008, Medicinal Plant Biotechnology: From Basic Research to Industrial Applications. Wiley-VCH, p. 29-48 20 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
NMR for gymnasieelever: forelæsningsslides, tabeller og opgavesamling til en NMR undervisningssession for gymnasieelever
Stærk, Dan, 2010, Institut for Grundvidenskab og Miljø, Københavns Universitet. 39 p.Research output: Book/Report › Compendium/lecture notes › Education
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A new class of spermidine-derived alkaloids
Stærk, Dan, Witt, M., Oketch-Rabah, H. A. & Jaroszewski, J. W., 2003, In: Organic Letters. 5, p. 2793-2796Research output: Contribution to journal › Journal article › Research › peer-review
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Spektroskopi – Strukturopklaring vha NMR og IR: Kompendium med forelæsningsslides, tabeller og opgavesamling til en undervisningsdag i spektroskopi ved Institut for Lægemiddeldesign og Farmakologi på Det Sundhedsvidenskabelige Fakultet, Københavns Universitet.
Stærk, Dan, 2016, 74 p.Research output: Book/Report › Compendium/lecture notes › Education
- Published
Vejledning til laboratorieøvelser i 'Organisk Kemi for Biovidenskab'
Stærk, Dan, 2012, Institut for Grundvidenskab og Miljø, Københavns Universitet. 74 p.Research output: Book/Report › Compendium/lecture notes › Education
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Når filmens fiktion bliver virkelighed
Stærk, Dan, Lambert, M., Sairafianpour, M., Clarkson, C. & Jaroszewski, J. W., 2004, In: Lægemiddelforskning. p. 12-13Research output: Contribution to journal › Journal article › Communication
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High-resolution bioactivity profiling combined with HPLC-HRMS-SPE-NMR: accelerated identification of bioactive constituents in food and medicinal plants
Stærk, Dan, 2015.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Cytotoxic activity of some phenanthroindolizidine N-Oxide alkaloids from Cynanchum vincetoxicum
Stærk, Dan, Christensen, J., Lemmich, E., Duus, J. Ø., Olsen, C. E. & Jaroszewski, J. W., 2000, In: Journal of Natural Products. 63, 11, p. 1584-1586Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bis-intercalation of homodimeric thiazole orange dyes in DNA: effect of modifying the linker
Stærk, Dan, Hamed, A. A., Pedersen, E. B. & Jacobsen, J. P., 1997, In: Bioconjugate Chemistry. 8, p. 869-877Research output: Contribution to journal › Journal article › Research › peer-review
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Phenanthroindolizidine alkaloids from Vincetoxicum pumilum
Stærk, Dan, Nezhad, K. B., Asili, J., Emami, S. A., Ahi, A., Sairafianpour, M. & Jaroszewski, J. W., 2005, In: Biochemical Systematics and Ecology. 33, p. 957-960Research output: Contribution to journal › Journal article › Research › peer-review
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High-resolution bioactivity profiling combined with hyphenated HPLC-SPE-NMR – Investigation of functional food and plants with antifungal constituents
Stærk, Dan, 2014.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Structural analysis of complex saponins of Balanites aegyptiaca by 800 MHz 1H NMR spectroscopy
Stærk, Dan, Chapagain, B. P., lindin, T., Wiesman, Z. & Jaroszewski, J. W., 2006, In: Magnetic Resonance in Chemistry. 44, p. 923-928Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Conformational studies of indole alkaloids corynantheine and dihydrocorynantheine by dynamic 1H NMR spectroscopy and computational methods: steric effects of ethyl vs. vinyl group
Stærk, Dan, Norrby, P. & Jaroszewski, J. W., 2001, In: Journal of Organic Chemistry. 66, p. 2217-2221Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fremtidens bæredygtige medicin fra naturen: Nye teknologier hjælper med at finde nålen i høstakken
Stærk, Dan, 2022, In: Pharma. 2022, 2, p. 20-22Research output: Contribution to journal › Contribution to newspaper - Newspaper article › Communication
- Published
Production of novel fusarielins by ectopic activation of the polyketide synthase 9 cluster in Fusarium graminearum
Sørensen, J. L., Hansen, F. T., Søndergaard, T. E., Stærk, Dan, Lee, T. V., Wimmer, R., Klitgaard, L. G., Purup, S., Giese, H. & Frandsen, R. J. N., 2012, In: Environmental Microbiology. 14, 5, p. 1159-1170 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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High-resolution Assays Combined with HPLC-HRMS-SPE-ttNMR for Identification of Antidiabetic Compounds in root of Scutellaria Baicalensis
Tahtah, Y., Jønsson, L. H., Nyberg, N., Jäger, A. & Stærk, Dan, 2014.Research output: Contribution to conference › Poster › Research
- Published
High-resolution PTP1B inhibition profiling combined with high-performance liquid chromatography - high-resolution mass spectrometry - solid-phase extraction - nuclear magnetic resonance spectroscopy: Proof-of-concept and antidiabetic constituents in crude extract of Eremophila lucida
Tahtah, Y., Wubshet, S. G., Kongstad, Kenneth Thermann, Heskes, A. M., Pateraki, Irini, Møller, Birger Lindberg, Jäger, A. & Stærk, Dan, 2016, In: Fitoterapia. 110, p. 52-58 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Triple aldose reductase/α-glucosidase/radical scavenging high-resolution profiling combined with high-performance liquid chromatography – high-resolution mass spectrometry – solid-phase extraction – nuclear magnetic resonance spectroscopy for identification of antidiabetic constituents in crude extract of Radix Scutellariae
Tahtah, Y., Kongstad, Kenneth Thermann, Wubshet, S. G., Nyberg, N., Jønsson, L. H., Jäger, A. K., Qinglei, S. & Stærk, Dan, 2015, In: Journal of Chromatography A. 1408, p. 125-132 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-resolution inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of PTP1B inhibitors from Vietnamese plants
Trinh, T. D. B., Jäger, A. K. & Stærk, Dan, 2017, In: Molecules. 22, 7, 12 p., 1228.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
α-Glucosidase inhibitors from Phyllanthus amarus and Phyllanthus urinaria
Trinh, T. D. B., Stærk, Dan & Jäger, A. K., Dec 2016, In: Planta Medica. 81, S 01, p. 1 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Screening for potential α-glucosidase and α-amylase inhibitory constituents from selected Vietnamese plants used to treat type 2 diabetes
Trinh, T. D. B., Stærk, Dan & Jäger, A. K., 2016, In: Journal of Ethnopharmacology. 186, p. 189-195 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Xanthones from the twigs of Garcinia oblongifolia and their antidiabetic activity
Trinh, T. D. B., Quach, T. T. T., Bui, D. N., Stærk, Dan, Nguyen, L. D. & Jäger, A. K., 2017, In: Fitoterapia. 118, p. 126-131Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1299056
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6333
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Identification of α-glucosidase inhibitors in apple peel - a chemometric approach
Research output: Contribution to conference › Poster › Research
Published -
4055
downloads
Itoside A and 4-hydroxytremulacin from Dovyalis caffra and Dovyalis zeyheri
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
3008
downloads
Identification of reaction products between drug substances and excipients by HPLC-SPE-NMR: Ester and amide formation between citric acid and 5-aminosalicylic acid
Research output: Contribution to journal › Journal article › Research › peer-review
Published