Christian Adam Olsen

Christian Adam Olsen

Professor

ORCID: 0000-0002-2953-8942

Publication year:
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76 - 100 out of 113Page size: 25
  1. 2018
  2. Published

    Synthesis of Trifluoromethyl Ketone Containing Amino Acid Building Blocks for the Preparation of Peptide-Based Histone Deacetylase (HDAC) Inhibitors

    Moreno Yruela, Carlos & Olsen, Christian Adam, 2018, In: Synthesis. 50, 20, p. 4037-4046

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Targeting Sirtuins: Substrate Specificity and Inhibitor Design

    Rajabi, N., Galleano, I., Madsen, A. S. & Olsen, Christian Adam, 3 Feb 2018, Progress in Molecular Biology and Translational Science: Sirtuins in Health and Disease. Elsevier, p. 25-69 (Progress in Molecular Biology and Translational Science, Vol. 154).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  4. Published

    Histone Deacetylase 11 Is an ε- N -Myristoyllysine Hydrolase

    Moreno Yruela, Carlos, Galleano, I., Madsen, A. S. & Olsen, Christian Adam, 3 May 2018, In: Cell Chemical Biology. 25, 7, p. 849-856

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    An NAD+-Dependent Sirtuin Depropionylase and Deacetylase (Sir2La) from the Probiotic Bacterium Lactobacillus acidophilus NCFM

    Olesen, S., Rajabi, N., Svensson, B., Olsen, Christian Adam & Madsen, A. S., 4 Jun 2018, In: Biochemistry. 57, 26, p. 3903-3915

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Direct Peptide Cyclization and One-Pot Modification Using the MeDbz Linker

    Gless, B. H. & Olsen, Christian Adam, 6 Aug 2018, In: Journal of Organic Chemistry. 83, 17, p. 10525-10534

    Research output: Contribution to journal › Letter › Research › peer-review

  7. Published

    Elucidating the Enzymatic Activity of HDAC11

    Moreno Yruela, Carlos, Galleano, I., Madsen, A. S. & Olsen, Christian Adam, 19 Aug 2018.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  8. Published

    Potent and selective inhibition of sirtuin 2 deacylation

    Nielsen, A. L., Rajabi, N., Madsen, A. & Olsen, Christian Adam, 19 Aug 2018.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  9. 2019
  10. Published

    Effect of co-inhabiting coagulase negative staphylococci on S. Aureus agr quorum sensing, host factor binding, and biofilm formation

    Peng, P., Baldry, M., Gless, B. H., Bojer, Martin Saxtorph, Espinosa-Gongora, C., Baig, S. J., Andersen, P. S., Olsen, Christian Adam & Ingmer, Hanne, 2019, In: Frontiers in Microbiology. 10, SEP, 14 p., 2212.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Kinetic Characterization of Inhibitors of Histone Deacetylases (HDACs) and Sirtuins

    Moreno Yruela, Carlos, Madsen, A. S. & Olsen, Christian Adam, 2019, 14 p.

    Research output: Working paper › Preprint

  12. Published

    Arylfluorosulfate-Based Electrophiles for Covalent Protein Labeling: A New Addition to the Arsenal

    Martín-Gago, P. & Olsen, Christian Adam, 21 Jan 2019, In: Angewandte Chemie - International Edition. 58, 4, p. 957-966 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  13. Published

    Functionalized Helical beta-Peptoids

    Wellhofer, I., Frydenvang, Karla Andrea, Kotesova, S., Christiansen, A. M., Laursen, J. S. & Olsen, Christian Adam, 5 Apr 2019, In: Journal of Organic Chemistry. 84, 7, p. 3762-3779

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Identification of autoinducing thiodepsipeptides from staphylococci enabled by native chemical ligation

    Gless, B. H., Bojer, Martin Saxtorph, Peng, P., Baldry, M., Ingmer, Hanne & Olsen, Christian Adam, 22 Apr 2019, In: Nature Chemistry. 11, p. 463–469

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Kinetic Tuning of HDAC Inhibitors Affords Potent Inducers of Progranulin Expression

    Moreno Yruela, Carlos, Fass, D. M., Cheng, C., Herz, J., Olsen, Christian Adam & Haggarty, S. J., 22 Jul 2019, In: A C S Chemical Neuroscience. 10, 8, p. 3769-3777

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. 2020
  17. Published

    Dethioacylation by sirtuins 1–3: Considerations for drug design using mechanism-based sirtuin inhibition

    Rajabi, N., Nielsen, A. L. & Olsen, Christian Adam, 2020, In: A C S Medicinal Chemistry Letters. 11, 10, p. 1886-1892

    Research output: Contribution to journal › Letter › Research › peer-review

  18. Published

    Hydroxamic Acid-Containing Peptides in the Study of Histone Deacetylases

    Moreno Yruela, Carlos & Olsen, Christian Adam, 2020, Topics in Medicinal Chemistry. A. M. (ed.). Springer, p. 29-54 26 p. (Topics in Medicinal Chemistry, Vol. 33).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  19. Published

    Increasing the Functional Group Diversity in Helical beta-Peptoids: Achievement of Solvent- and pH-Dependent Folding

    Wellhofer, I., Beck, J., Frydenvang, Karla Andrea, Brase, S. & Olsen, Christian Adam, 2020, In: Journal of Organic Chemistry. 85, 16, p. 10466-10478 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Peptide Inhibitors of the α-Cobratoxin-Nicotinic Acetylcholine Receptor Interaction

    Lynagh, T., Kiontke, S., Meyhoff-Madsen, M., Gless, B. H., Johannesen, J., Kattelmann, S., Christiansen, A., Dufva, M., Laustsen, A. H., Devkota, K., Olsen, Christian Adam, Kuemmel, D., Pless, Stephan & Lohse, B., 2020, In: Journal of Medicinal Chemistry. 63, 22, p. 13709-13718 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Selective inhibitors of SIRT2 regulate perinuclear α-tubulin acetylation, migration, and invasion of breast cancer cells

    Nielsen, A. L., Rajabi, N., Kudo, N., Jørgensen, Kathrine Lundø, Fontenas, M., Lucidi, A., Madsen, A. S., Yoshida, M. & Olsen, Christian Adam, 2020, In: bioRxiv. 26 p.

    Research output: Contribution to journal › Journal article › Research

  22. Published

    Finding the gas pedal on a slow sirtuin

    Nielsen, A. L. & Olsen, Christian Adam, 31 Jan 2020, In: Journal of Biological Chemistry. 295, p. 400-401

    Research output: Contribution to journal › Literature review › Research › peer-review

  23. Published

    Photo Cross-Linking Probes Containing ϵ-N-Thioacyllysine and ϵ-N-Acyl-(δ-aza)lysine Residues

    Bæk, M., Martín-Gago, P., Laursen, J. S., Madsen, J. L. H., Chakladar, S. & Olsen, Christian Adam, 23 Mar 2020, In: Chemistry - A European Journal. 26, 17, p. 3862-3869 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. 2021
  25. Published

    High-throughput screening of histone deacetylases and determination of kinetic parameters using fluorogenic assays

    Moreno Yruela, Carlos & Olsen, Christian Adam, 2021, In: STAR Protocols. 2, 1, 14 p., 100313.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Mechanism-based inhibitors of SIRT2: structure–activity relationship, X-ray structures, target engagement, regulation of α-tubulin acetylation and inhibition of breast cancer cell migration

    Nielsen, A. L., Rajabi, N., Kudo, N., Jørgensen, Kathrine Lundø, Moreno Yruela, Carlos, Bæk, M., Fontenas, M., Lucidi, A., Madsen, A. S., Yoshida, M. & Olsen, Christian Adam, 2021, In: RSC Chemical Biology. 2, p. 612-626

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Mitochondria-targeted inhibitors of the human SIRT3 lysine deacetylase

    Troelsen, K. S., Bæk, M., Nielsen, A. L., Madsen, A. S., Rajabi, N. & Olsen, Christian Adam, 2021, In: RSC Chemical Biology. 2, p. 627-635

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Rearrangement of Thiodepsipeptides by S → N Acyl Shift Delivers Homodetic Autoinducing Peptides

    Gless, B. H., Bejder, Benjamin Svejdal, Monda, F., Bojer, Martin Saxtorph, Ingmer, Hanne & Olsen, Christian Adam, 2021, In: Journal of the American Chemical Society. 143, 28, p. 10514–10518

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    SIRT5 Is a Druggable Metabolic Vulnerability in Acute Myeloid Leukemia

    Yan, D., Franzini, A., Pomicter, A. D., Halverson, B. J., Antelope, O., Mason, C. C., Ahmann, J. M., Senina, A. V., Vellore, N. A., Jones, C. L., Zabriskie, M. S., Than, H., Xiao, M. J., van Scoyk, A., Patel, A. B., Clair, P. M., Heaton, W. L., Owen, S. C., Andersen, J. L., Egbert, C. M. & 11 others, Reisz, J. A., D'Alessandro, A., Cox, J. E., Gantz, K. C., Redwine, H. M., Iyer, S. M., Khorashad, J. S., Rajabi, N., Olsen, Christian Adam, O'Hare, T. & Deininger, M. W., 2021, In: Cancer Discovery. 2, 3, p. 266-287

    Research output: Contribution to journal › Comment/debate › Research › peer-review

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