Dan Stærk

Dan Stærk

Head of Department, Visiting professor

ORCID: 0000-0003-0074-298X

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  1. Published

    Hemolymph metabolites and osmolality are tightly linked to cold tolerance of Drosophila species: a comparative study

    Olsson, T., MacMillan, H. A., Nyberg, N., Stærk, Dan, Malmendal, A. & Overgaard, J., 15 Aug 2016, In: The Journal of Experimental Biology. 219, 16, p. 2504-2513 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    High-resolution α-amylase assay combined with high-performance liquid chromatography−solid-phase extraction−nuclear magnetic resonance spectroscopy for expedited identification of α-amylase inhibitors – proof of concept and α-amylase inhibitor in cinnamon.

    Okutan, L., Kongstad, Kenneth Thermann, Jäger, A. & Stærk, Dan, 2014, In: Journal of Agricultural and Food Chemistry. 62, 47, p. 11465-11471 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Ligand-fishing and bioactivity-correlated metabolomics for accelerated discovery of antidiabetic drug leads

    Nyberg, N. T., Wubshet, S. G., Kongstad, Kenneth Thermann & Stærk, Dan, Dec 2016, In: Planta Medica. 82, S 01

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  4. Published

    An inverse association between plasma benzoxazinoid metabolites and PSA after rye intake in men with prostate cancer revealed with a new method

    Nordin, E., Steffensen, S. K., Laursen, B. B., Andersson, S., Johansson, J., Åman, P., Hallmans, G., Borre, M., Stærk, Dan, Hanhineva, K., Fomsgaard, I. S. & Landberg, R., 2022, In: Scientific Reports. 12, 14 p., 5260.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    New resistance-correlated saponins from the insect-resistant crucifer Barbarea vulgaris

    Nielsen, Nikoline Juul, Nielsen, J. & Stærk, Dan, 2010, In: Journal of Agricultural and Food Chemistry. 58, 9, p. 5509-5514 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Identification of Amaryllidaceae alkaloids in larvae of the ‘lily borer’ moth Brithys crini

    Nair, J. J., Andresen, A. L., Papenfus, H., Stærk, Dan & van Staden, J., 2020, In: South African Journal of Botany. 131, p. 351-359

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    A GPCR-based yeast biosensor for biomedical, biotechnological, and point-of-use cannabinoid determination

    Miettinen, Karel, Leelahakorn, Nattawat, Almeida Robles, A. R., Zhao, Yong, Hansen, L. R., Nikolajsen, I. E., Andersen, Jens Bo, Givskov, Michael, Stærk, Dan, Bak, Søren & Kampranis, Sotirios, 2022, In: Nature Communications. 13, 16 p., 3664.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Identification and characterization of a new antifungal peptide in fermented milk product containing bioprotective Lactobacillus cultures

    McNair, Laura M., Siedler, S., Vinther, J. M., Hansen, A. M., Neves, A. R., Jäger, A. K., Franzyk, Henrik & Stærk, Dan, 2018, In: F E M S Yeast Research. 18, 9 p., foy094.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    The causal mutation leading to sweetness in modern white lupin cultivars

    Mancinotti, Davide, Czepiel, K., Taylor, J. L., Galehshahi, H. G., Møller, L. A., Jensen, M. K., Motawie, Mohammed Saddik, Hufnagel, B., Soriano, A., Yeheyis, L., Kjaerulff, Louise, Péret, B., Stærk, Dan, Wendt, T., Nelson, M. N., Kroc, M. & Geu-Flores, Fernando, 2023, In: Science Advances. 9, 31, 10 p., eadg8866.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Antidiabetic xanthones with α-glucosidase inhibitory activities from an endophytic Penicillium canescens

    Malik, A., Ardalani, H., Anam, S., McNair, Laura M., Kromphardt, K. J. K., Frandsen, R. J. N., Franzyk, Henrik, Stærk, Dan & Kongstad, Kenneth Thermann, 2020, In: Fitoterapia. 142, 8 p., 104522.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    α-Glucosidase inhibitory activity of plant extracts from the Danish Medicinal Plant Biobank

    Madsen, A. T., Soelberg, Jens & Stærk, Dan, 8 Jun 2021. 1 p.

    Research output: Contribution to conference › Poster › Research

  12. Published

    Oxidation and cyclization of Casbene in the biosynthesis of Euphorbia factors from mature seeds of Euphorbia lathyris L

    Luo, Dan, Callari, R., Hamberger, B., Wubshet, S. G., Nielsen, M. T., Andersen-Ranberg, Johan, Hallström, B. M., Cozzi, F., Heider, H., Møller, Birger Lindberg, Stærk, Dan & Hamberger, B. R., 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 34, p. E5082-E5089 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    High-resolution snake venom inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of antivenomous constituents in Clausena excavata

    Liu, Y., Nyberg, N., Stærk, Dan & Jäger, A., 2015.

    Research output: Contribution to conference › Poster › Research

  14. Published

    High-resolution bacterial growth inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of antibacterial constituents in Chinese plants used to treat snakebites

    Liu, Y., Nielsen, M., Stærk, Dan & Jäger, A., 2014, In: Journal of Ethnopharmacology. 155, 2, p. 1276-1283 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    High-resolution hyaluronidase inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of anti-necrosis constituents in Chinese plants used to treat snakebite

    Liu, Y., Stærk, Dan, Nielsen, M. N., Nyberg, N. & Jäger, A. K., 2015, In: Phytochemistry. 119, p. 62-69 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Facilitated visual interpretation of scores in principal component analysis by bioactivity-labeling of 1H NMR spectra - metabolomics investigation and identification of a new α-glucosidase inhibitor in Radix Astragali

    Liu, Y., Nyberg, N., Jäger, A. K. & Stærk, Dan, 2017, In: Molecules. 22, 3, 12 p., 411.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    High-resolution snake venom inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of antivenomous constituents in Clausena excavata

    Liu, Y., Nyberg, N., Stærk, Dan & Jäger, A. K., 26 Aug 2015.

    Research output: Contribution to conference › Poster › Research

  18. Published

    High-resolution hyaluronidase inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of anti-necrosis constituents in Clausena excavata

    Liu, Y., Stærk, Dan, Nyberg, N. & Jager, A. K., Nov 2015, In: Planta Medica. 81, 16, p. 1432-1432

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  19. Published

    High-resolution α-glucosidase and radical scavenging profiling combined with HPLC-HRMS-SPE-NMR for identification of bioactive constituents in crude extract of Pueraria lobata

    Liu, B., Kongstad, Kenneth Thermann, Nyberg, N., Qinglei, S., Jäger, A. K. & Stærk, Dan, 26 Aug 2015.

    Research output: Contribution to conference › Poster › Research

  20. Published

    Dual High-Resolution α-Glucosidase and Radical Scavenging Profiling Combined with HPLC-HRMS-SPE-NMR for Identification of Minor and Major Constituents Directly from the Crude Extract of Pueraria lobata

    Liu, B., Kongstad, Kenneth Thermann, Qinglei, S., Nyberg, N., Jäger, A. & Stærk, Dan, 13 Feb 2015, In: Journal of Natural Products. 78, 2, p. 294–300 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Edible seaweed as future functional food: Identification of α-glucosidase inhibitors by combined use of high-resolution α-glucosidase inhibition profiling and HPLC-HRMS-SPE-NMR

    Liu, B., Kongstad, Kenneth Thermann, Wiese, S., Jäger, A. K. & Stærk, Dan, 2016, In: Food Chemistry. 203, p. 16-22 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    High-resolution α-glucosidase and radical scavenging profiling combined with HPLC-HRMS-SPE-NMR for identification of bioactive constituents in crude extract of Pueraria lobata

    Liu, B., Kongstad, Kenneth Thermann, Nyberg, N., Qinglei, S., Jäger, A. & Stærk, Dan, 2015.

    Research output: Contribution to conference › Poster › Research

  23. Published

    High-resolution α-glucosidase and radical scavenging profiling combined with HPLC-HRMS-SPE-NMR for identification of bioactive constituents in crude extract of Pueraria lobata

    Liu, B., Kongstad, Kenneth Thermann, Nyberg, N. T., Sun, Q., Jager, A. K. & Stærk, Dan, Nov 2015, In: Planta Medica. 81, 16, p. 1437-1437

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  24. Published

    The α-glucosidase and PTP1B inhibitory effect of 45 medicinal plants extracts

    Liu, B., Kongstad, Kenneth Thermann, Jäger, A. K. & Stærk, Dan, Dec 2016, In: Planta Medica. 81, S 01, p. 1 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  25. Published

    Peptides from chicken processing by-product inhibit DPP-IV and promote cellular glucose uptake: potential ingredients for T2D management

    Lima, R. D. C. L., Berg, R. S., Rønning, S. B., Afseth, N. K., Knutsen, S. H., Stærk, Dan & Wubshet, S. G., 2019, In: Food & Function. 10, p. 1619-1628

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Advancing HPLC-PDA-HRMS-SPE-NMR analysis of coumarins in Coleonema album by use of orthogonal reversed-phase C18 and pentafluorophenyl separations

    Lima, R. D. C. L., Gramsbergen, S., Van Staden, J., Jäger, A. K., Kongstad, Kenneth Thermann & Stærk, Dan, 2017, In: Journal of Natural Products. 80, 4, p. 1020-1027

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    High-resolution PTP1B inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of PTP1B inhibitors from Miconia albicans

    Lima, R. D. C. L., Kongstad, Kenneth Thermann, Kato, L., José das Silva, M., Franzyk, Henrik & Stærk, Dan, 2018, In: Molecules. 23, 7, 13 p., 1755.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Brazilian insulin plant as a bifunctional food: Dual high-resolution PTP1B and α-glucosidase inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of antidiabetic compounds in Myrcia rubella Cambess

    Lima, R. D. C. L., Kato, L., Kongstad, Kenneth Thermann & Stærk, Dan, 2018, In: Journal of Functional Foods. 45, p. 444-451

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Butenolides from plant-derived smoke: natural plant-growth regulators with antagonistic actions on seed germination

    Light, M. E., Burger, B. V., Stærk, Dan, Kohout, L. & Van Staden, J., 2010, In: Journal of Natural Products. 73, 2, p. 267-269 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Potential of Myrtus communis Linn. as a bifunctional food: Dual high-resolution PTP1B and α-glucosidase inhibition profiling combined with HPLC-HRMS and NMR for identification of antidiabetic triterpenoids and phloroglucinol derivatives

    Liang, Chao, Stærk, Dan & Kongstad, Kenneth Thermann, 2020, In: Journal of Functional Foods. 64, 10 p., 103623.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Dual high-resolution α-glucosidase and PTP1B profiling combined with HPLC-PDA-HRMS-SPE-NMR analysis for the identification of potentially antidiabetic chromene meroterpenoids in Rhododendron capitatum

    Liang, Chao, Kjaerulff, Louise, Hansen, Paul Robert, Kongstad, Kenneth Thermann & Stærk, Dan, 2021, In: Journal of Natural Products. 84, p. 2454-2467

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Eremane, viscidane and isozizaene diterpenoids from the leaves of Eremophila rigida and their absolute configurations

    Liang, Chao, Ndi, C., Semple, S., Buirchell, B., Coriani, S., Møller, Birger Lindberg & Stærk, Dan, 2024, In: Phytochemistry. 219, 16 p., 113972.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Characterization of serrulatane diterpenoids in Eremophila phyllopoda subsp. phyllopoda by triple high-resolution α-glucosidase/PTP1B/radical scavenging profiling, NMR spectroscopy, DFT-GIAO NMR, and electronic circular dichroism calculations

    Liang, Chao, Ndi, C., Kjaerulff, Louise, Semple, S., Buirchell, B., Coriani, S., Møller, Birger Lindberg & Stærk, Dan, 2023, In: Journal of Natural Products. 86, 4, p. 694–709

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Characterization of antidiabetic serrulatane diterpenoids from Eremophila phyllopoda by triple high-resolution α-glucosidase / PTP1B / radical scavenging profiling

    Liang, Chao, Ndi, C., Semple, S., Coriani, S., Møller, Birger Lindberg & Stærk, Dan, 2021. 1 p.

    Research output: Contribution to conference › Poster › Research

  35. Published

    Identification of new PTP1B-inhibiting decipiene diterpenoid esters from Eremophila clarkei by high-resolution PTP1B inhibition profiling, enzyme kinetics analysis, and molecular docking

    Liang, Chao, Zang, J., Ndi, C., Semple, S., Buirchell, B., Coriani, S., Møller, Birger Lindberg & Stærk, Dan, 2023, In: Bioorganic Chemistry. 139, 15 p., 106744.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Identification of α-glucosidase inhibitors in Machilus litseifolia by combined use of high-resolution α-glucosidase inhibition profiling and HPLC-PDA-HRMS-SPE-NMR

    Li, T., Kongstad, Kenneth Thermann & Stærk, Dan, 2019, In: Journal of Natural Products. 82, p. 249-258

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Structure elucidation of prenyl- and geranyl substituted coumarins in Gerbera piloselloides by NMR spectroscopy, electronic circular dichroism calculations, and single crystal X-ray crystallography

    Li, T., Ma, X., Fedotov, D., Kjaerulff, Louise, Frydenvang, Karla Andrea, Coriani, S., Hansen, Paul Robert, Kongstad, Kenneth Thermann & Stærk, Dan, 8 Apr 2020, In: Molecules. 25, 25 p., 1706.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Food preference and performance of the larvae of a specialist herbivore: variation among and within host-plant populations

    Leimu, R., Riipi, M. & Stærk, Dan, 2005, In: Acta Oecologica. 28, p. 325-330

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Application of rotated PCA models to facilitate interpretation of metabolite profiles: commercial preparations of St. John's wort

    Lawaetz, A. J., Schmidt, B., Stærk, Dan, Jaroszewski, J. W. & Bro, Rasmus, 2009, In: Planta Medica. 75, 3, p. 271-279 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Application of Rotated PCA Models to Facilitate Interpretation of Metabolite Profiles: Commercial Preparations of St. John's Wort

    Lawaetz, A. J., Schmidt, B., Stærk, Dan, Jaroszewski, J. W. & Bro, Rasmus, 2009, In: Planta Medica.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Identification of reaction products between drug substances and excipients by HPLC-SPE-NMR: Ester and amide formation between citric acid and 5-aminosalicylic acid

    Larsen, J. T., Stærk, Dan, Cornett, Claus, Hansen, S. H. & Jaroszewski, J. W., 2009, In: Journal of Pharmaceutical and Biomedical Analysis. 49, p. 839-842

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    High-resolution α-glucosidase inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of anti-diabetic compounds in Eremanthus crotonoides (Asteraceae)

    Lana e Silva, E., Felipe Revoredo Lobo, J., Vinther, J. M., Moreira Borges, R. & Stærk, Dan, 2016, In: Molecules. 21, 6, 19 p., 782.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Identification of natural products using HPLC-SPE combined with CapNMR

    Lambert, M., Wolfender, J., Stærk, Dan, Christensen, Søren Brøgger, Hostettmann, K. & Jaroszewski, J. W., 2007, In: Analytical Chemistry. 79, 2, p. 727-735

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    HPLC-SPE-NMR hyphenation in natural products research: optimization of analysis of Croton membranaceus extract

    Lambert, M., Stærk, Dan, Hansen, S. H. & Jaroszewski, J. W., 2005, In: Magnetic Resonance in Chemistry. 43, p. 771-775

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Rapid extract dereplication using HPLC-SPE-NMR: analysis of isoflavonoids from Smirnowia iranica

    Lambert, M., Stærk, Dan, Hansen, S. H., Sairafianpour, M. & Jaroszewski, J. W., 2005, In: Journal of Natural Products. 68, p. 1500-1509

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Investigation of the mechanism and chemistry underlying Staphylococcus aureus' ability to inhibit Pseudomonas aeruginosa growth in vitro

    Kvich, Lasse Andersson, Crone, S. G., Christensen, M. H., Lima, R. D. C. L., Alhede, M., Alhede, M., Stærk, Dan & Bjarnsholt, Thomas, 2022, In: Journal of Bacteriology. 204, 11, 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Simultaneous quantification of high-dose naloxone and naloxone-3-β-D-glucuronide in human plasma by UHPLC-MS/MS

    Kongstad, Kenneth Thermann, Papathanasiou, T., Springborg, A., Lund, Trine Meldgaard, Werner, M. U. & Stærk, Dan, 2019, In: Bioanalysis. 11, 03, p. 165-173

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Fungal plasma membrane H+-ATPase inhibitory activity of o-hydroxybenzylated flavanones and chalcones from Uvaria chamae P. Beauv

    Kongstad, Kenneth Thermann, Wubshet, S. G., Kjellerup, L., winther, A. L. & Stærk, Dan, 20 Jun 2015, In: Fitoterapia. 105, p. 102-106 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Combined use of high-resolution α-glucosidase inhibition profiling and HPLC-HRMS-SPE-NMR for investigation of antidiabetic principles in crude plant extracts

    Kongstad, Kenneth Thermann, Özdemir, C., Barzak, A., Wubshet, S. G. & Stærk, Dan, 5 Feb 2015, In: Journal of Agricultural and Food Chemistry. 63, 8, p. 2257-2263 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    HPLC-SPE-NMR for combinatorial biosynthetic investigations – expanding the landscape of diterpene structural diversity

    Kongstad, Kenneth Thermann, Andersen-Ranberg, Johan, Hamberger, B. R. & Stærk, Dan, 2016. 1 p.

    Research output: Contribution to conference › Poster › Research

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