Dan Stærk
Head of Department, Visiting professor
Administration and Operations
Jagtvej 160
2100 København Ø
Biopharmaceuticals
Jagtvej 162
2100 København Ø
- 2024
- Published
Eremane, viscidane and isozizaene diterpenoids from the leaves of Eremophila rigida and their absolute configurations
Liang, Chao, Ndi, C., Semple, S., Buirchell, B., Coriani, S., Møller, Birger Lindberg & Stærk, Dan, 2024, In: Phytochemistry. 219, 16 p., 113972.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxetane ring formation in taxol biosynthesis is catalyzed by a bifunctional cytochrome P450 enzyme
Zhao, Yong, zpm303, zpm303, Xie, Yuman, Duan, Y. T., Andeadelli, A., Pateraki, Irini, Makris, A. M., Pomorski, Thomas Guenther, Stærk, Dan & Kampranis, Sotirios, 2024, In: Journal of the American Chemical Society. 146, p. 801-810Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Biosynthesis and biotechnological production of the anti-obesity agent celastrol
Zhao, Yong, Hansen, N. L., Duan, Yaotao, Prasad, M., Motawie, Mohammed Saddik, Møller, Birger Lindberg, Pateraki, Irini, Stærk, Dan, Bak, Søren, Miettinen, Karel & Kampranis, Sotirios, 2023, In: Nature Chemistry. 15, p. 1236–1246Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of serrulatane diterpenoids in Eremophila phyllopoda subsp. phyllopoda by triple high-resolution α-glucosidase/PTP1B/radical scavenging profiling, NMR spectroscopy, DFT-GIAO NMR, and electronic circular dichroism calculations
Liang, Chao, Ndi, C., Kjaerulff, Louise, Semple, S., Buirchell, B., Coriani, S., Møller, Birger Lindberg & Stærk, Dan, 2023, In: Journal of Natural Products. 86, 4, p. 694–709Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of new PTP1B-inhibiting decipiene diterpenoid esters from Eremophila clarkei by high-resolution PTP1B inhibition profiling, enzyme kinetics analysis, and molecular docking
Liang, Chao, Zang, J., Ndi, C., Semple, S., Buirchell, B., Coriani, S., Møller, Birger Lindberg & Stærk, Dan, 2023, In: Bioorganic Chemistry. 139, 15 p., 106744.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Orthogonal reversed-phase C18 and pentafluorophenyl HPLC separation for phytochemical profiling of serrulatanes in Eremophila denticulata
Zhao, Yong, Li, T., Kjaerulff, Louise, Venter, H., Coriani, S., Møller, Birger Lindberg, Semple, S. & Stærk, Dan, 2023, In: Journal of Natural Products. 86, 12, p. 2638-2650Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polypharmacology-labeled molecular networking: An analytical technology workflow for accelerated identification of multiple bioactive constituents in complex extracts
Zhao, Yong, Gericke, Oliver, Li, T., Kjaerulff, Louise, Kongstad, Kenneth Thermann, Heskes, A. M., Møller, Birger Lindberg, Jørgensen, Flemming Steen, Venter, H., Coriani, S., Semple, S. J. & Stærk, Dan, 2023, In: Analytical Chemistry. 95, 9, p. 4381-4389 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Semi-synthesis of novel thebaine derivatives with low cytotoxicity and their antibacterial and antihemolytic properties
Hasanpour, Z., Salehi, P., Aliahmadi, A., Hoseinpour, M., Behboodi, H., Stærk, Dan & Bararjanian, M., 2023, In: Medicinal Chemistry Research. 32, p. 1713–1725Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The causal mutation leading to sweetness in modern white lupin cultivars
Mancinotti, Davide, Czepiel, K., Taylor, J. L., Galehshahi, H. G., Møller, L. A., Jensen, M. K., Motawie, Mohammed Saddik, Hufnagel, B., Soriano, A., Yeheyis, L., Kjaerulff, Louise, Péret, B., Stærk, Dan, Wendt, T., Nelson, M. N., Kroc, M. & Geu-Flores, Fernando, 2023, In: Science Advances. 9, 31, 10 p., eadg8866.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Tripterygium wilfordii cytochrome P450s catalyze the methyl shift and epoxidations in the biosynthesis of triptonide
Hansen, N. L., Kjaerulff, Louise, Heck, Q. K., Forman, Victor, Stærk, Dan, Møller, Birger Lindberg & Andersen-Ranberg, Johan, 2022, In: Nature Communications. 13, 5011.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A GPCR-based yeast biosensor for biomedical, biotechnological, and point-of-use cannabinoid determination
Miettinen, Karel, Leelahakorn, Nattawat, Almeida Robles, A. R., Zhao, Yong, Hansen, L. R., Nikolajsen, I. E., Andersen, Jens Bo, Givskov, Michael, Stærk, Dan, Bak, Søren & Kampranis, Sotirios, 2022, In: Nature Communications. 13, 16 p., 3664.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A gene cluster in Ginkgo biloba encodes unique multifunctional cytochrome P450s that initiate ginkgolide biosynthesis
Forman, Victor, Luo, Dan, Geu-Flores, Fernando, Lemcke, René, Nelson, D., Kampranis, Sotirios, Stærk, Dan, Møller, Birger Lindberg & Pateraki, Irini, 2022, In: Nature Communications. 13, 14 p., 5143.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An inverse association between plasma benzoxazinoid metabolites and PSA after rye intake in men with prostate cancer revealed with a new method
Nordin, E., Steffensen, S. K., Laursen, B. B., Andersson, S., Johansson, J., Åman, P., Hallmans, G., Borre, M., Stærk, Dan, Hanhineva, K., Fomsgaard, I. S. & Landberg, R., 2022, In: Scientific Reports. 12, 14 p., 5260.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ancient biosynthesis in an oil crop: Glucosinulate profiles in Limnanthes alba and its relatives (Limnanthaceae, Brassicales)
Agerbirk, Niels, Pattison, David, Mandáková, T., Lysak, M. A., Montaut, S. & Stærk, Dan, 2022, In: Journal of Agricultural and Food Chemistry. 70, p. 1134-1147Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biodiscoveries within the Australian plant genus Eremophila based on international and interdisciplinary collaboration: results and perspectives on outstanding ethical dilemmas
Semple, S., Stærk, Dan, Buirchell, B., Fowler, R., Gericke, Oliver, Kjaerulff, Louise, Zhao, Yong, Pedersen, H. A., Petersen, M. J., Rasmussen, L. F., Bredahl, E. K., Pedersen, Gustav Blichfeldt, McNair, Laura M., Ndi, C., Hansen, N. L., Heskes, A., Bayly, M., Loland, Claus Juul, Heinz, Nanna & Møller, Birger Lindberg, 2022, In: Plant Journal. 111, 4, p. 936-953 15866.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Data-dependent acquisition-mass spectrometry guided isolation of new benzoxazinoids from the roots of Acanthus mollis L.
Bhattarai, B., Steffensen, S. K., Stærk, Dan, Laursen, B. B. & Fomsgaard, I. S., 2022, In: International Journal of Mass Spectrometry. 474, 10 p., 116815.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expanding the terpene biosynthetic code with non-canonical 16 carbon atom building blocks
Ignea, C., Raadam, Morten Hessellund, Koutsaviti, A., Zhao, Yong, Duan, Yaotao, Harizani, M., Miettinen, Karel, Georgantea, P., Rosenfeldt, M., Viejo-Ledesma, S. E., Petersen, Mikael Agerlin, Bredie, Wender, Stærk, Dan, Roussis, V., Ioannou, E. & Kampranis, Sotirios, 2022, In: Nature Communications. 13, 16 p., 5188.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fremtidens bæredygtige medicin fra naturen: Nye teknologier hjælper med at finde nålen i høstakken
Stærk, Dan, 2022, In: Pharma. 2022, 2, p. 20-22Research output: Contribution to journal › Contribution to newspaper - Newspaper article › Communication
- Published
Investigation of the mechanism and chemistry underlying Staphylococcus aureus' ability to inhibit Pseudomonas aeruginosa growth in vitro
Kvich, Lasse Andersson, Crone, S. G., Christensen, M. H., Lima, R. D. C. L., Alhede, M., Alhede, M., Stærk, Dan & Bjarnsholt, Thomas, 2022, In: Journal of Bacteriology. 204, 11, 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Isolation and structure elucidation of caryophyllane sesquiterpenoids from leaves of Eremophila spathulata
Bredahl, E. K., Kjaerulff, Louise, Ndi, C., Semple, S., Buirchell, B., Møller, Birger Lindberg & Stærk, Dan, 2022, In: Phytochemistry Letters. 47, p. 156-163Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Serrulatane diterpenoids from the leaves of Eremophila glabra and their potential as antihyperglycemic drug leads
Petersen, M. J., Liang, Chao, Kjaerulff, Louise, Ndi, C., Semple, S., Buirchell, B., Coriani, S., Møller, Birger Lindberg & Stærk, Dan, 2022, In: Phytochemistry. 196, 11 p., 113072.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Serrulatane diterpenoids with unusual side chain modifications from root bark of Eremophila longifolia
Rasmussen, L. F., Anton, Jennifer, Kjaerulff, Louise, Zhao, Yong, Semple, S. J., Ndi, C., Buirchell, B., Møller, Birger Lindberg & Stærk, Dan, 2022, In: Phytochemistry. 203, 14 p., 113408.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Insects as sources for sustainable peptide drugs against type 2 diabetes
Didriksen, A. H., Petersen, M. J. & Stærk, Dan, 8 Jun 2021. 1 p.Research output: Contribution to conference › Poster › Research
- Published
α-Glucosidase inhibitory activity of plant extracts from the Danish Medicinal Plant Biobank
Madsen, A. T., Soelberg, Jens & Stærk, Dan, 8 Jun 2021. 1 p.Research output: Contribution to conference › Poster › Research
- Published
A systematic review of possible interactions for herbal medicines and dietary supplements used concomitantly with disease-modifying or symptom-alleviating multiple sclerosis drugs
Petersen, M. J., Bergien, Sofie Olsgaard & Stærk, Dan, 2021, In: Phytotherapy Research. 35, 7, p. 3610-3631Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1299056
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Identification of α-glucosidase inhibitors in apple peel - a chemometric approach
Research output: Contribution to conference › Poster › Research
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4056
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Itoside A and 4-hydroxytremulacin from Dovyalis caffra and Dovyalis zeyheri
Research output: Contribution to journal › Journal article › Research › peer-review
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3009
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Identification of reaction products between drug substances and excipients by HPLC-SPE-NMR: Ester and amide formation between citric acid and 5-aminosalicylic acid
Research output: Contribution to journal › Journal article › Research › peer-review
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