Bente Vestergaard

Bente Vestergaard

Professor Emerita, Professor emeritus.

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    ORCID: 0000-0001-8011-6414

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    1. Published

      A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage

      Bach, Anders, Clausen, B. H., Møller, M., Vestergaard, Bente, Chi, C. N., Round, A., Sørensen, P. L., Nissen, K. B., Kastrup, Jette Sandholm Jensen, Gajhede, Michael, Jemth, P., Kristensen, Anders Skov, Lundström, P., Lambertsen, K. L. & Strømgaard, Kristian, 28 Feb 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 9, p. 3317-3322

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Diverse bacterial genomes encode an operon of two genes, one of which is a unusual class-I release factor that potentially recognizes atypical mRNA signals other than normal stop codons

      Baranov, P., Vestergaard, Bente, Hamelryck, Thomas Wim, Gesteland, Nyborg, J. & Atking, J., 2006, In: Biology Direct. 13, p. 1-28 28 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency

      Beich-Frandsen, M., Pickering, Darryl S, Mirza, Osman Asghar, Johansen, Tommy Nørskov, Greenwood, J., Vestergaard, Bente, Schousboe, Arne, Gajhede, Michael, Liljefors, T. & Kastrup, Jette Sandholm Jensen, 2008, In: Journal of Medicinal Chemistry. 51, 5, p. 1459-63

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Disentangling the role of solvent polarity and protein solvation in folding and self-assembly of α-lactalbumin

      Bucciarelli, S., Sayedi, E. S., Osella, S., Trzaskowski, B., Vissing, K. J., Vestergaard, Bente & Foderà, Vito, 2020, In: Journal of Colloid and Interface Science. 561, p. 749-761 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Size-exclusion chromatography small-angle X-ray scattering of water soluble proteins on a laboratory instrument

      Bucciarelli, S., Midtgaard, S. R., Pedersen, M. N., Skou, S., Arleth, Lise & Vestergaard, Bente, 2018, In: Journal of Applied Crystallography. 51, 6, p. 1623-1632 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Protein-protein interactions: a supra-structural phenomenon demanding trans-disciplinary biophysical approaches

      Byron, O. & Vestergaard, Bente, Dec 2015, In: Current Opinion in Structural Biology. 35, p. 76-86 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Avidity within the N-terminal anchor drives α-synuclein membrane interaction and insertion

      Cholak, E., Bugge, K., Khondker, A., Gauger, K., Pedraz-Cuesta, E., Pedersen, M. E., Bucciarelli, S., Vestergaard, Bente, Pedersen, Stine Helene Falsig, Rheinstädter, M. C., Langkilde, Annette Eva & Kragelund, Birthe Brandt, 2020, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 34, 6, p. 7462-7482 21 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Distinct α-Synuclein:Lipid Co-Structure Complexes Affect Amyloid Nucleation through Fibril Mimetic Behavior

      Cholak, E., Bucciarelli, S., Bugge, K., Johansen, Nicolai Tidemand, Vestergaard, Bente, Arleth, Lise, Kragelund, Birthe Brandt & Langkilde, Annette Eva, Nov 2019, In: Biochemistry. 58, 50, p. 5052-5065

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Trifluoroethanol modulates α-synuclein amyloid-like aggregate formation, stability and dissolution

      Di Carlo, M. G., Vetri, V., Buscarino, G., Leone, M., Vestergaard, Bente & Foderà, Vito, Sep 2016, In: Biophysical Chemistry. 216, p. 23-30 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Large-scale polymorphism and auto-catalytic effect in insulin fibrillogenesis

      Foderà, Vito, van de Weert, Marco & Vestergaard, Bente, 2010, In: Soft Matter. 6, 18, p. 4413-4419

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Observation of the Early Structural Changes Leading to the Formation of Protein Superstructures

      Foderà, Vito, Vetri, V., Wind, T. S., Noppe, W., Cornett, Claus, Donald, A. M., Morozova-Roche, L. A. & Vestergaard, Bente, 18 Sep 2014, In: Journal of Physical Chemistry Letters. 5, 18, p. 3254-3258 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Tyr702 is an important determinant of agonist binding and domain closure of the ligand-binding core of GluR2

      Frandsen, A., Pickering, Darryl S, Vestergaard, Bente, Kasper, C., Nielsen, B. B., Greenwood, J. R., Campiani, G., Fattorusso, C., Gajhede, Michael, Schousboe, Arne & Kastrup, Jette Sandholm Jensen, 2005, In: Molecular Pharmacology. 67, 3, p. 703-13 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Low-resolution structure of a vesicle disrupting a-synuclein oligomer that accumulates during fibrillation

      Giehm, L., Svergun, D. I., Otzen, D. E. & Vestergaard, Bente, 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 8, p. 3246-3251

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Considerably Unfolded Transthyretin Monomers Preceed and Exchange with Dynamically Structured Amyloid Protofibrils

      Groenning, M., Campos, R. I., Hirschberg, D., Hammarström, P. & Vestergaard, Bente, 2015, In: Scientific Reports. 5, p. 1-18 18 p., 11443.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Recognition by tryptophanyl-tRNA synthetases of discriminator base on tRNATrp from three biological domains

      Guo, Q., Vestergaard, Bente, Costa, Degres, Wong, Grosjean, Zhu, Wong & Xue, 2002, In: Journal of Biological Chemistry. 277, p. 14343-14349 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Time-resolved SAXS measurements facilitated by online HPLC buffer exchange

      Jensen, M. H., Toft, K. N., David, G., Havelund, S., Pérez, J. & Vestergaard, Bente, 2010, In: Journal of Synchrotron Radiation. 17, 6, p. 769-773

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Self-association of long-acting insulin analogues studied by size exclusion chromatography coupled to multi-angle light scattering

      Jensen, M. H., Wahlund, P., Jacobsen, J. K., Vestergaard, Bente, van de Weert, Marco & Havelund, S., 2011, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 879, 28, p. 2945-2951

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Small angle X-ray scattering-based elucidation of the self-association mechanism of human insulin analogue lys(B29)(N(e)¿-carboxyheptadecanoyl) des(B30)

      Jensen, M. H., Wahlund, P., Toft, K. N., Jacobsen, J. K., Steensgaard, D. B., van de Weert, Marco, Havelund, S. & Vestergaard, Bente, 15 Jan 2013, In: Biochemistry. 52, 2, p. 282-94 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Formation mechanism of insulin fibrils and structural aspects of the insulin fibrillation process

      Jensen, M. G., Frøkjær, Sven & Vestergaard, Bente, 2009, In: Current Protein and Peptide Science. 10, 5, p. 509-528

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Kimen til de farlige fibriller

      Jensen, M. G. & Vestergaard, Bente, 2007, In: Aktuel Naturvidenskab. 6, p. 12-15

      Research output: Contribution to journal › Journal article › Communication

    21. Published

      Gennembrud i forståelsen af insulinfibrillering

      Jensen, M. G., Vestergaard, Bente, Frøkjær, Sven, Gajhede, Michael, Flink, J. M., van de Weert, Marco, Kastrup, Jette Sandholm Jensen & Svergun, D. I., 2007, In: Lægemiddelforskning. p. 10-11

      Research output: Contribution to journal › Journal article › Communication

    22. Published

      Size-Selective Phagocytic Clearance of Fibrillar α-Synuclein through Conformational Activation of Complement Receptor 4

      Juul-madsen, K., Qvist, P., Bendtsen, K. L., Langkilde, Annette Eva, Vestergaard, Bente, Howard, K. A., Dehesa-etxebeste, M., Paludan, S. R., Andersen, G. R., Jensen, P. H., Otzen, D. E., Romero-ramos, M. & Vorup-jensen, T., 22 Jan 2020, In: The Journal of Immunology. 204, 5, p. 1345-1361

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Small angle X-ray studies reveal that Aspergillus niger glucoamylase has a defined extended conformation and can form dimers in solution

      Jørgensen, A. D., Nøhr, J., Kastrup, Jette Sandholm Jensen, Gajhede, Michael, Sigurskjold, B. W., Sauer, J., Svergun, D. I., Svensson, B. & Vestergaard, Bente, 2008, In: Journal of Biological Chemistry. 283, 21, p. 14772-14780

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Structure of dimeric and tetrameric complexes of the BAR domain protein PICK1 determined by small-angle X-Ray scattering

      Karlsen, M. L., Thorsen, T. S., Johner, N., Ammendrup-Johnsen, I., qrc243, qrc243, Tian, X., Simonsen, J. B., Hoiberg-Nielsen, R., Christensen, N. M., Khelashvili, G., Streicher, W., Teilum, Kaare, Vestergaard, Bente, Weinstein, H., Gether, Ulrik, Arleth, Lise & Madsen, Kenneth Lindegaard, 7 Jul 2015, In: Structure. 23, 7, p. 1258-1270 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Structure of the E. coli ribosomal termination complex with release factor 2

      Klaholz, B., Pape, T., Zavialov, A., Myasnikov, Orlova, Vestergaard, Bente, Ehrenberg, M. & van Heel, M., 2003, In: Nature. 421, p. 90-94 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      A new small-angle X-ray scattering set-up on the crystallography beamline I711 at MAX-lab

      Knaapila, M., Svensson, C., Barauskas, J., Zackrisson, M., Nielsen, S. S., Toft, K. N., Vestergaard, Bente, Arleth, Lise, Olsson, U., Pedersen, J. S. & Cerenius, Y., 2009, In: Journal of Synchrotron Radiation. 16, 4, p. 498-504 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Synergies within the natural sciences at the University of Copenhagen: an interfaculty evaluation of barriers and opportunities to improve the quality of infrastructure, research and education

      Krogsgaard-Larsen, Povl, Møller, Birger Lindberg, Larsen, Erik Hviid, Vestergaard, Bente, Lunde, C., Stæhr, P. A. & Andersen, J. (ed.), 2009, Faculty of Life Sciences: Museum Tusculanum. 43 p.

      Research output: Book/Report › Book › Research

    28. Published

      Structural model and trans-interaction of the entire ectodomain of the olfactory cell adhesion molecule

      Kulahin, N., Kristensen, O., Rasmussen, K. K., Olsen, L., Rydberg, P., Vestergaard, Bente, Kastrup, Jette Sandholm Jensen, Berezin, V., Bock, E., Walmod, P. S. & Gajhede, Michael, 9 Feb 2011, In: Structure. 19, 2, p. 203-211

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Automated microfluidic sample-preparation platform for high-throughput structural investigation of proteins by small-angle X-ray scattering

      Lafleur, J., Snakenborg, D., Nielsen, S. S., Møller, M., Toft, K. N., Menzel, A., Jacobsen, J. K., Vestergaard, Bente, Arleth, Lise & Kutter, J. P., 2011, In: Journal of Applied Crystallography. 44, p. 1090-1099 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Methods for structural characterization of prefibrillar intermediates and amyloid fibrils

      Langkilde, Annette Eva & Vestergaard, Bente, 2009, In: FEBS Letters. 583, 16, p. 2600-2609

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Noninvasive Structural Analysis of Intermediate Species During Fibrillation: An Application of Small-Angle X-Ray Scattering

      Langkilde, Annette Eva, Herranz-Trillo, F., Bernadó, P. & Vestergaard, Bente, 8 Jun 2018, Amyloid Proteins: methods and protocols. Sigurdsson, E., Calero, M. & Gasset, M. (eds.). Humana Press, Vol. 1779. p. 209-239 31 p. (Methods in Molecular Biology).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

    32. Published

      Protein fibrillation from another small angle—SAXS data analysis of developing systems

      Langkilde, Annette Eva & Vestergaard, Bente, 2023, Methods in Enzymology. Elsevier, Vol. 678. p. 377-409

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    33. Published

      Structural characterization of prefibrillar intermediates and amyloid fibrils by small-angle X-ray scattering

      Langkilde, Annette Eva & Vestergaard, Bente, 2012, Amyloid proteins: methods and protocols. Sigurdsson, E. M., Calero, M. & Gasset, M. (eds.). 2 ed. New York: Springer Science+Business Media, Vol. 849. p. 137-155 18 p. (Methods in Molecular Biology, Vol. 849).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

    34. Published

      The architecture of amyloid-like peptide fibrils revealed by X-ray scattering, diffraction and electron microscopy

      Langkilde, Annette Eva, Morris, K. L., Serpell, L. C., Svergun, D. I. & Vestergaard, Bente, Apr 2015, In: Acta crystallographica. Section D, Biological crystallography. 71, Pt 4, p. 882-95 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Mechanistic study of the inhibitory activity of Geum urbanum extract against α-Synuclein fibrillation

      Lobbens, E. S., Breydo, L., Pedersen, T. S., Vestergaard, Bente, Jäger, A. K., Jørgensen, Lene, Uversky, V. & van de Weert, Marco, 21 Jun 2016, In: B B A - Proteins and Proteomics. 1864, 9, p. 1160-1169 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      SAS-Based Studies of Protein Fibrillation

      Marasini, C. & Vestergaard, Bente, 2017, Biological Small Angle Scattering: Techniques, Strategies and Tips. Springer Science+Business Media, Vol. 1009. p. 149-165 17 p. (Advances in Experimental Medicine and Biology).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    37. Published

      Sucrose modulates insulin amyloid-like fibril formation: effect on the aggregation mechanism and fibril morphology

      Marasini, C., Foderà, Vito & Vestergaard, Bente, 2017, In: RSC Advances. 7, p. 10487-10493

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      High concentration formulation studies of an IgG2 antibody using small angle X-ray scattering

      Mosbæk, C. R., Konarev, P., Svergun, D. I., Rischel, C. & Vestergaard, Bente, 2012, In: Pharmaceutical Research. 29, 8, p. 2225-2235

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Extensive small-angle X-ray scattering studies of blood coagulation factor VIIa reveal interdomain flexibility

      Mosbæk, C. R., Nolan, D., Persson, E., Svergun, D. I., Bukrinsky, J. T. & Vestergaard, Bente, 2010, In: Biochemistry. 49, 45, p. 9739-9745

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Small Angle X-Ray Scattering Studies of Mitochondrial Glutaminase C Reveal Extended Flexible Regions, and Link Oligomeric State with Enzyme Activity

      Møller, M., Nielsen, S. S., Ramachandran, S., Li, Y., Tria, G., Streicher, W., Petoukhov, M. V., Cerione, R. A., Gillilan, R. E. & Vestergaard, Bente, 30 Sep 2013, In: P L o S One. 8, 9, e74783.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Crystal structure of the kainate receptor GluR5 ligand-binding core in complex with (S)-glutamate

      Naur, P., Vestergaard, Bente, Skov, L., Egebjerg, J., Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 2005, In: FEBS Letters. 579, p. 1154-60

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Ionotropic glutamate-like receptor d2 binds D-serine and glycine.

      Naur, P., Hansen, K. B., Kristensen, Anders Skov, Dravid, S. M., Pickering, Darryl S, Olsen, L., Vestergaard, Bente, Egebjerg, J., Gajhede, Michael, Traynelis, S. F. & Kastrup, Jette Sandholm Jensen, 2007, In: Proceedings of the National Academy of Science of the United States of America. 104, 35, p. 14116-14121

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      BioXTAS RAW, a software program for high-throughput automated small-angle X-ray scattering data reduction and preliminary analysis

      Nielsen, S. S., Toft, K. N., Snakenborg, D., Jeppesen, Mads Gravers, Jacobsen, J. K., Vestergaard, Bente, Kutter, J. P. & Arleth, Lise, 2009, In: Journal of Applied Crystallography. 42, 5, p. 959-964 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Wildtype and A30P mutant alpha-synuclein form different fibril structures

      Nielsen, S. B., Macchi, F., Raccosta , S., Langkilde, Annette Eva, Giehm, L., Kyrsting, A. H., Svane, A. S. P., Manno, M., Christiansen, G., Nielsen, N. C., Oddershede, L. B., Vestergaard, Bente & Otzen, D., 2013, In: PLOS ONE. 8, 7, e67713.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Direct Correlation Between Ligand-Induced α-Synuclein Oligomers and Amyloid-like Fibril Growth

      Pedersen, M. N., Foderà, Vito, Horvath, I., van Maarschalkerweerd, A., Nørgaard Toft, K., Weise, C., Almqvist, F., Wolf-Watz, M., Wittung-Stafshede, P. & Vestergaard, Bente, 2015, In: Scientific Reports. 5, p. 1-12 12 p., 10422.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Structural Investigations of on-pathway Oligomers of α-Synuclein

      Pedersen, M. N., Horvath, I., Weise, C. F., Foderà, Vito, Wittung-Stafshede, P., Wolf-Watz, M., Toft, K. N. & Vestergaard, Bente, 31 May 2012.

      Research output: Contribution to conference › Poster › Research

    47. Published

      Monoclonal Antibodies Follow Distinct Aggregation Pathways During Production-Relevant Acidic Incubation and Neutralization

      Pedersen, T. S., Tian, X., Thorolfsson, M., Karkov, H. S., Rasmussen, H. B., Langkilde, Annette Eva & Vestergaard, Bente, Mar 2016, In: Pharmaceutical Research. 33, 3, p. 716-28 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. A cryo-electron microscopic study of ribosome-bound termination factor RF2

      Rawat, Zavialov, A., Sengupta, Valle, Grasucci, Linde, Vestergaard, Bente, Ehrenberg, M. & Frank, J., 2003, In: Nature. 421, p. 87-90 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Structure and thermodynamics of transient protein-protein complexes by chemometric decomposition of SAXS datasets

      Sagar, A., Herranz-Trillo, F., Langkilde, Annette Eva, Vestergaard, Bente & Bernadó, P., 2021, In: Structure. 29, 9, p. 1074-1090

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      The Non-Fibrillating N-Terminal of α-Synuclein Binds and Co-Fibrillates with Heparin

      Skaanning, L. K., Santoro, A., Skamris, T., Martinsen, J. H., D’Ursi, A. M., Bucciarelli, S., Vestergaard, Bente, Bugge, K., Langkilde, Annette Eva & Kragelund, Birthe Brandt, 2020, In: Biomolecules. 10, 8, 23 p., 1192.

      Research output: Contribution to journal › Journal article › Research › peer-review

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