Christian Adam Olsen
Professor
Biopharmaceuticals
Jagtvej 162
2100 København Ø
- 2016
- Published
Investigating the Sensitivity of NAD(+)-dependent Sirtuin Deacylation Activities to NADH
Madsen, A. S., Andersen, C., Daoud, M., Anderson, K. A., Laursen, J. S., Chakladar, S., Huynh, F. K., Colaco, A. R., Backos, D. S., Fristrup, P., Hirschey, M. D. & Olsen, Christian Adam, 25 Mar 2016, In: Journal of Biological Chemistry. 291, 13, p. 7128-7141 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Optoepigenetics: An acetylation photoswitch
Madsen, A. S. & Olsen, Christian Adam, May 2016, In: Nature Chemical Biology. 12, 5, p. 306-7 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Innovative Strategies for Selective Inhibition of Histone Deacetylases
Maolanon, A. R., Madsen, A. S. & Olsen, Christian Adam, 21 Jul 2016, In: Cell Chemical Biology. 23, 7, p. 759-768 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipids Reprogram Metabolism to Become a Major Carbon Source for Histone Acetylation
McDonnell, E., Crown, S. B., Fox, D. B., Kitir, B., Ilkayeva, O. R., Olsen, Christian Adam, Grimsrud, P. A. & Hirschey, M. D., 1 Nov 2016, In: Cell Reports. 17, 6, p. 1463-1472 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Cyclic tetrapeptide HDAC inhibitors as potential therapeutics for spinal muscular atrophy: Screening with iPSC-derived neuronal cells
Lai, J. I., Leman, L. J., Ku, S., Vickers, C. J., Olsen, Christian Adam, Montero, A., Ghadiri, M. R. & Gottesfeld, J. M., 2017, In: Bioorganic and Medicinal Chemistry Letters. 27, 15, p. 3289-3293 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Natural and Synthetic Macrocyclic Inhibitors of the Histone Deacetylase Enzymes
Maolanon, A., Kristensen, H., Leman, L., Ghadiri, R. & Olsen, Christian Adam, 2017, In: ChemBioChem. 18, 1, p. 5-49 45 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Scalable and Purification-Free Synthesis of a Myristoylated Fluorogenic Sirtuin Substrate
Galleano, I., Nielsen, J., Stahl Madsen, A. & Olsen, Christian Adam, 2017, In: SYNLETT: Accounts and Rapid Communications in Chemical Synthesis. 28, 16, p. 2169-2173Research output: Contribution to journal › Letter › Research › peer-review
- Published
Structure-activity relationship study based on Autoinducing Peptide (AIP) from dog pathogen S. schleiferi
Gless, B. H., Peng, P., Pedersen, K. D., Gotfredsen, C. H., Ingmer, Hanne & Olsen, Christian Adam, 2017, In: Organic Letters. 19, 19, p. 5276–5279Research output: Contribution to journal › Letter › Research › peer-review
- Published
SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion
Anderson, K. A., Huynh, F. K., Fisher-Wellman, K., Stuart, J. D., Peterson, B. S., Douros, J. D., Wagner, G. R., Thompson, J. W., Madsen, A. S., Green, M. F., Sivley, R. M., Ilkayeva, O. R., Stevens, R. D., Backos, D. S., Capra, J. A., Olsen, Christian Adam, Campbell, J. E., Muoio, D. M., Grimsrud, P. A. & Hirschey, M. D., 4 Apr 2017, In: Cell Metabolism. 25, 4, p. 838-855.e15Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chemical Editing of Macrocyclic Natural Products and Kinetic Profiling Reveal Slow, Tight-Binding Histone Deacetylase Inhibitors with Picomolar Affinities
Kitir, B., Maolanon, A. R., Ohm, R. G., Colaço, A. R., Fristrup, P., Madsen, A. S. & Olsen, Christian Adam, 26 Sep 2017, In: Biochemistry. 56, 38, p. 5134-5146 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 101364066
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2040
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Synthesis and antiangiogenic activity of N-alkylated levamisole derivatives
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
390
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Cross-Talk between Staphylococcus aureus and Other Staphylococcal Species via the agr Quorum Sensing System
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
359
downloads
The agr inhibitors solonamide B and analogues alter immune responses to Staphylococccus aureus but do not exhibit adverse effects on immune cell functions
Research output: Contribution to journal › Journal article › Research › peer-review
Published