Elisabeth Rexen Ulven

Elisabeth Rexen Ulven

Associate Professor

ORCID: 0000-0003-1243-7587

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  1. The Pharmacology of TUG-891, a Potent and Selective Agonist of the Free Fatty Acid Receptor 4 (FFA4/GPR120), Demonstrates Both Potential Opportunity and Possible Challenges to Therapeutic Agonism

    Hudson, B. D., Shimpukade, B., Mackenzie, A. E., Butcher, A. J., Pediani, J. D., Ulven, Elisabeth Rexen, Heathcote, H., Tobin, A. B., Ulven, Trond & Milligan, G., 2013, In: Molecular Pharmacology. 84, 5, p. 710-725 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Structure-based discovery of novel US28 small molecule ligands with different modes of action

    Lückmann, Michael, Amarandi, R., Papargyri, N., Jakobsen, M. H., Ulven, Elisabeth Rexen, Jensen, Lars Juhl, Pui, A., Schwartz, Thue W., Rosenkilde, Mette & Frimurer, Thomas Michael, 2017, In: Chemical Biology & Drug Design. 89, 3, p. 289–296

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Structure-activity study of dihydrocinnamic acids and discovery of the potent FFA1 (GPR40) agonist TUG-469

    Ulven, Elisabeth Rexen, Due-Hansen, M. E., Urban, C., Merten, N., Pfleiderer, M., Karlsen, K. K., Rasmussen, S. S., Steensgaard, M., Hamacher, A., Schmidt, J., Drewke, C., Petersen, R. K., Kristiansen, Karsten, Ullrich, S., Kostenis, E., Kassack, M. U. & Ulven, Trond, 2010, In: ACS Medicinal Chemistry Letters. 1, 7, p. 345-349 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  4. Published

    Structure-Activity Relationship Studies of Tetrahydroquinolone Free Fatty Acid Receptor 3 Modulators

    Ulven, Elisabeth Rexen, Quon, T., Sergeev, E., Barki, N., Brvar, M., Hudson, B. D., Dutta, P., Hansen, A. H., Bielefeldt, L. Ø., Tobin, A. B., McKenzie, C. J., Milligan, G. & Ulven, Trond, 9 Apr 2020, In: Journal of Medicinal Chemistry. 63, 7, p. 3577-3595 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Structure-Activity Relationship Studies and Optimization of 4-Hydroxypyridones as GPR84 Agonists

    Ieremias, L., Kaspersen, M. H., Manandhar, Asmita, Schultz-Knudsen, Katrine, Vrettou, C. I., Pokhrel, R., Heidtmann, C. V., Jenkins, L., Kanellou, C., Marsango, S., Li, Y., Bräuner, Hans, Ulven, Elisabeth Rexen, Milligan, G. & Ulven, Trond, 2024, In: Journal of Medicinal Chemistry. 67, 5, p. 3542-3570

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Structure-Activity Relationship Explorations and Discovery of a Potent Antagonist for the Free Fatty Acid Receptor 2

    Hansen, A. H., Christensen, H. B., Pandey, S. K., Sergeev, E., Valentini, Alice, Dunlop, J., Dedeo, D., Fratta, S., Hudson, B. D., Milligan, G., Ulven, Trond & Ulven, Elisabeth Rexen, 2021, In: ChemMedChem. 16, 21, p. 3326-3341

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Structure-Activity Investigations and Optimisations of Non-metabolite Agonists for the Succinate Receptor 1

    Ulven, Elisabeth Rexen, Trauelsen, Mette, Brvar, M., Lückmann, Michael, Bielefeldt, L. Ø., Jensen, L. K. I., Schwartz, Thue W. & Frimurer, Thomas Michael, 2018, In: Scientific Reports. 8, 1, p. 1-18 10010.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3

    Schmidt, J., Smith, N. J., Ulven, Elisabeth Rexen, Tikhonova, I. G., Grundmann, M., Hudson, B. D., Ward, R. J., Drewke, C., Milligan, G., Kostenis, E. & Ulven, Trond, 10 Jan 2011, In: Journal of Biological Chemistry. 286, 12, p. 10628-10640 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Reevaluation of Fatty acid receptor 1 (FFAR1/GPR40) as drug target for the stimulation of insulin secretion in humans

    Wagner, R., Kaiser, G., Gerst, F., Ulven, Elisabeth Rexen, Due-Hansen, M. E., Grundmann, M., Machicao, F., Peter, A., Kostenis, E., Ulven, Trond, Fritsche, A., Häring, H. & Ullrich, S., 1 Feb 2013, In: Diabetes. 62, 6, p. 2106-2111 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Receptor structure-based discovery of non-metabolite agonists for the succinate receptor GPR91

    Trauelsen, Mette, Ulven, Elisabeth Rexen, Hjorth, Siv Annegrethe, Brvar, M., Monaco, C., Frimurer, Thomas Michael & Schwartz, Thue W., Dec 2017, In: Molecular Metabolism. 6, 12, p. 1585-1596 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 201719978