Flemming Steen Jørgensen
Professor
Structural Biology
Universitetsparken 2
2100 København Ø
- 1979
- Published
Disulfide conformational analysis. The nature of the S-S rotation barrier1 1 Organo-Sulphur Mechanisms-9. For Part 8 see L. Carlsen and J.P. Snyder, J. Org. Chem. 43, 2216 (1978).
Jørgensen, Flemming Steen & Snyder, J. P., 1 Jan 1979, In: Tetrahedron. 35, 11, p. 1399-1407 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1980
- Published
Crystal and Molecular Structure of Di- tert-adamantyl Disulfide. Extension of the Correlation between the Sulfur-Sulfur Dihedral Angle and the Sulfur Lone-Pair Energy Gap
Rindorf, G., Jørgensen, Flemming Steen & Snyder, J. P., 1 Jan 1980, In: Journal of Organic Chemistry. 45, 26, p. 5343-5347 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Search for a trans-Disulfide: Structural Analysis of Di-tert-adamantyl Disulfide by Photoelectron Spectroscopy, Derivation of σI (t-Ad), and Molecular Mechanics Calculations for Related Bulky Disulfides
Jørgensen, Flemming Steen & Snyder, J. P., 1 Jan 1980, In: Journal of Organic Chemistry. 45, 6, p. 1015-1020 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1981
- Published
Determination of ring inversion barriers for 1H,3H-naphtho[1,8-cd]-pyran and its methyl substituted derivatives by molecular mechanics calculations and dynamic nuclear magnetic resonance spectroscopy
Anderson, J. E. & Jørgensen, Flemming Steen, 1 Jan 1981, In: Journal of the Chemical Society, Perkin Transactions 2. 4, p. 741-746 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polyethers. Structural analysis of the 1,4,5,8-tetraoxadecalins and 2,2'-bis(1,3-dioxolane) by photoelectron spectroscopy, molecular mechanics and molecular orbital calculations
Jørgensen, Flemming Steen, Nørskov-Lauritsen, L., Jensen, R. B. & Sshroll, G., 1 Jan 1981, In: Tetrahedron. 37, 21, p. 3671-3679 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sulfur-Bridged pen-Naphthalenes: Synthesis, Conformational Analysis, and Photoelectron Spectroscopy of the Mono-, Di-, and Trisulfides of 1,8-Dimethylnaphthalene
Guttenberger, H. G., Bestmann, H. J., Dickert, F. L., Jørgensen, Flemming Steen & Snyder, J. P., 1 Jan 1981, In: Journal of the American Chemical Society. 103, 1, p. 159-168 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Electronic Structure of β-Thioxoketones. A Photoelectron Spectroscopic Study of the Enol-Enethiol Tautomerism of Thioacetylacetone and Related Compounds
Jørgensen, Flemming Steen, Carlsen, L. & Duus, F., 1 Jan 1981, In: Journal of the American Chemical Society. 103, 6, p. 1350-1353 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1982
- Published
Anti,anti acetals : Photoelectron spectroscopy of trans-1,8-dioxadecalins
Jørgensen, Flemming Steen & Nørskov-Lauritsen, L., 1982, In: Tetrahedron Letters. 23, 49, p. 5221 - 5224Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Correlations between Core Photoionization Energies (EB1s) and Gas-Phase Basicity. A General Method for Determining Sites of Protonation and Intramolecular Ion Reorganization Energies
Buschek, J. M., Jørgensen, Flemming Steen & Brown, R. S., 1 Jan 1982, In: Journal of the American Chemical Society. 104, 19, p. 5019-5025 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ring inversion of CH2-X-CH2-bridged peri-naphthalenes. A dynamic n.m.r. study
Anderson, J. E., Jørgensen, Flemming Steen & Thomsen, T., 1 Jan 1982, In: Journal of the Chemical Society, Chemical Communications. 6, p. 333-334 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
X-ray Photoelectron Spectroscopic Study of the Enol-Enethiol Tautomerism of Thioacetylacetone and Related β-Thioxoketones
Jørgensen, Flemming Steen, Brown, R. S., Carlsen, L. & Duus, F., 1 Jan 1982, In: Journal of the American Chemical Society. 104, 22, p. 5922-5926 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1983
- Published
On the molecular and electronic features of syn- and anti-sequinorbornene
Jørgensen, Flemming Steen, 1983, In: Tetrahedron Letters. 24, 47, p. 5289 - 5292Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On the presence of extremely short H...H non-bonded distances, and orbital interactions through eight s bonds or through two methylene groups in tetramethanonaphthacenes.
Jørgensen, Flemming Steen & Paddon-Row, M. N., 1983, In: Tetrahedron Letters. 24, 48, p. 5415 - 5418Research output: Contribution to journal › Journal article › Research › peer-review
- Published
cis-disulfides protelectron spectrum of a 6,7-dithiabicyclo[3.2.1]octane
Jørgensen, Flemming Steen & McCabe, P. H., 1983, In: Tetrahedron Letters. 24, 3, p. 319-322Research output: Contribution to journal › Journal article › Research › peer-review
- Published
1,2‐Oxathiolane – A Photoelectron Spectroscopic Study
Jørgensen, Flemming Steen & Carlsen, L., 1 Jan 1983, In: Chemische Berichte. 116, 6, p. 2374-2377 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Photoelectron spectra of some decahydrotrimethanoanthracenes: Observation of large π orbital interactions through six bonds and an apparent violation of the trans rule
Jørgensen, Flemming Steen, Paddon-Row, M. N. & Patney, H. K., 1 Jan 1983, In: Journal of the Chemical Society, Chemical Communications. 10, p. 573-575 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Crystal structure of merosinigrin, an (ap,ap)-monothioacetal; structural properties of the thioglycosidic linkage
Nørskov-Lauritsen, L., Jørgensen, Flemming Steen & Jaroszewski, J. W., 11 Nov 1983, In: Carbohydrate Research. 123, 1, p. 1-11 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1984
- Published
3-mercaptopropanal
Carlsen, L., Jørgensen, Flemming Steen, Egsgaard, H. & Nicolaisen, F. M., 1 Jan 1984, In: Journal of the Chemical Society, Perkin Transactions 2. 4, p. 609-613 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Number connection test and continuous reaction times in assessment of organic and metabolic encephalopathy: a comparative study
Elsass, P., Christensen, S. E., Jørgensen, Flemming Steen, Mortensen, Erik Lykke & Vilstrup, H., Feb 1984, In: Acta Pharmacologica et Toxicologica. 54, 2, p. 115-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1985
- Published
Cyclynes. Part 5. Pericyclynes: "exploded cycloalkanes" with unusual orbital interactions and conformational properties. MM2 and STO-3G calculations, x-ray crystal structures, photoelectron spectra, and electron transmission spectra
Houk, K. N., Scott, L. T., Rondan, N. G., Spellmeyer, D. C., Reinhardt, G., Hyun, J. L., DeCicco, G. J., Weiss, R., Chen, M. H. M., Bass, L. S., Clardy, J., Jørgensen, Flemming Steen, Eaton, T. A., Sarkozi, V., Petit, C. M., Ng, L. & Jordan, K. D., 1985, In: Journal of the American Chemical Society. 107, 23, p. 6556-6562 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Crystal and Molecular Structure of anti-Sesquinorbornene
Gaihede, M., Jørgensen, Flemming Steen, Kopecky, K. R., Watson, W. H. & Kashyap, R. P., 1 Jan 1985, In: Journal of Organic Chemistry. 50, 22, p. 4395-4397 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cyclic Acetals. Structural Analysis of 1,3‐Dioxepine and Related Compounds
Jørgensen, Flemming Steen, Gajhede, Michael & Frei, B., 1 Jan 1985, In: Helvetica Chimica Acta. 68, 8, p. 2148-2157 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1987
- Published
Crystal structures and photoelectron spectra of some trimethanoanthracenes, tetramethanonaphthacenes, and pentamethanopentacenes. Experimental evidence for laticyclic hyperconjugation
Paddon-Row, M. N., Englehardt, L. M., Skelton, B. W., White, A. H., Jørgensen, Flemming Steen & Patney, H. K., 1987, In: J. Chem. Soc., Perkin Trans. 2. p. 1835-1850 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Setting the anomeric effect against steric effects in simple acyclic acetals. Non-anomeric non-classical conformations. An n.m.r. and molecular mechanics investigation
Anderson, J. E., Heki, K., Hirota, M. & Jørgensen, Flemming Steen, 1987, In: Chemical communications (Cambridge, England). 1987, p. 554-555 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Towards an identification of the pyrethroid pharmacophore. A molecular modelling study of some pyrethroid esters
Byberg, J. R., Jørgensen, Flemming Steen & Klemmensen, P. D., 1987, In: Journal of Computer - Aided Molecular Design. 1, 3, p. 181-95 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular modelling of GABA uptake inhibitors
Jørgensen, Flemming Steen & Thøgersen, H., 1 Jan 1987, In: Nordic Journal of Psychiatry. 41, 6, p. 483-486 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1988
- Published
peri-Interaction, ortho-interaction, and barriers to internal rotation. A dynamic nuclear magnetic resonance and molecular mechanics investigation of 1,2-dineopentylbenzene and 1,8-dineopentylnaphthalene
Anderson, J. E., Barkel, D. J. & Jørgensen, Flemming Steen, 1 Feb 1988, In: Journal of the Chemical Society. Perkin Transactions 2 (2001). 2, p. 199-202 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Conformational analysis of peri-interactions in napththalene derivatives. Ring inversion in CH2–X–CH2-bridged peri-naphthalenes
Anderson, J. E. & Jørgensen, Flemming Steen, 1 Apr 1988, In: Journal of the Chemical Society. Perkin Transactions 2 (2001). 1988, 4, p. 469-471 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1989
- Published
3D-QSAR. Towards a quantitative three-dimensional description of muscarinic agonists.
Lagersted, A. & Jørgensen, Flemming Steen, 1 Jan 1989, In: Progress in Clinical and Biological Research. 291, p. 333-336 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heterocyclic muscarinic agonists: Structural and therapeutic aspects
Krogsgaard-Larsen, Povl, Jensen, B., Falch, E. & Jørgensen, Flemming Steen, 1 Jan 1989, In: Drugs of the Future. 14, 6, p. 541-561 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1990
- Published
Relationship between structure, conformational flexibility, and biological activity of agonists and antagonists at the N-methyl-D-aspartic acid subtype of excitatory amino acid receptors
Madsen, Ulf, Brehm, L., Schaumburg, K., Jørgensen, Flemming Steen & Krogsgaard-Larsen, Povl, 1990, In: Journal of Medicinal Chemistry. 33, 1, p. 374-80 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural and stereochemical requirements for interactions with subtypes of central excitatory amino acid receptors
Brehm, L., Christensen, I. T., Nielsen, Birgitte, Reinhardt, A., Ebert, B., Madsen, Ulf, Jørgensen, Flemming Steen, Hansen, J. J. & Krogsgaard-Larsen, Povl, 1990, Frontiers in Drug Research; Alfred Benzon Symposium 28. Jensen, B., Jørgensen, F. S. & Kofod, H. (eds.). Copenhagen: Munksgaard , p. 92-105 14 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- 1991
- Published
Conformational and pharmacological characterization of 4-AHCP, a bicyclic homologue of the excitatory amino acid receptor agonist AMPA
Lund, Trine Meldgaard, Madsen, Ulf, Ebert, B., Jørgensen, Flemming Steen & Krogsgaard-Larsen, Povl, 1991, In: Med. Chem. Res. 1, p. 136-141 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Excitatory amino acid receptors: multiplicity and structural requirements for activation and blockade
Krogsgaard-Larsen, Povl, Lund, Trine Meldgaard, Jørgensen, Flemming Steen & Brehn, L., 1991, Excitatory amino acids and synaptic function. Wheal, H. & Thomson, A. (eds.). London: Academic Press, p. 1-17 17 p. (Excitatory Amino Acids and Synaptic Transmission, Academic Press, London).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Primary structure and conformational analysis of peptide methionine-tyrosine, a peptide related to neuropeptide Y and peptide YY isolated from lamprey intestine
Conlon, J. M., Bjørnholm, B., Jørgensen, Flemming Steen, Youson, J. H. & Schwartz, T. W., 1991, In: European Journal of Biochemistry. 199, 2, p. 293-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1992
- Published
AMPA receptor agonists: structural, conformational and stereochemical aspects
Hansen, J., Jørgensen, Flemming Steen, Lund, Trine Meldgaard, Nielsen, Birgitte, Reinhardt, A., Breum, I., Brehm, L. & Krogsgaard-Larsen, Povl, 1992, Excitatory Amino Acid Receptors. Krogsgaard-Larsen, P. & Hansen, J. J. (eds.). Ellis Horwood: Chichester, 30 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Conformational analysis of the fungicide fenpropimorph by molecular mechanics calculations and NMR spectroscopy
Kastrup, Jette Sandholm Jensen, Jørgensen, Flemming Steen, Klemmensen, P. D., Hacksell, U. & Petersson, I., 1992, In: Journal of Pesticide Science. 36, p. 309-318 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Substrate-enzyme interactions and catalytic mechanism in phospholipase C: a molecular modeling study using the GRID program
Byberg, J. R., Jørgensen, Flemming Steen, Hansen, S. & Hough, E., 1992, In: Proteins: Structure, Function, and Bioinformatics. 12, 4, p. 331-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1993
- Published
Conservation of a helix-stabilizing dipole moment in the PP-fold family of regulatory peptides
Bjørnholm, B., Jørgensen, Flemming Steen & Schwartz, Thue W., 1993, In: Biochemistry. 32, 12, p. 2954-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Three-dimensional structures of human phospholipase A2 from pancreas and synovial fluid by model building
Christensen, I. T., Jørgensen, Flemming Steen, Svensson, L. A. & Högberg, T., 1993, In: Drug Design and Discovery. 10, 2, p. 101-13 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Conformational analysis and molecular modelling of a partial GABA(A) agonist and a glycine antagonist related to the GABA(A) agonist, THIP
Byberg Buur, J. R., Hjeds, H., Krogsgaard-Larsen, Povl & Jørgensen, Flemming Steen, 1 Dec 1993, In: Drug Design and Discovery. 10, 3, p. 213-229 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1994
- Published
GABAA receptor agonists, partial agonists, and antagonists. Design and therapeutic prospects
Krogsgaard-Larsen, Povl, Frølund, Bente, Jørgensen, Flemming Steen & Schousboe, Arne, 1994, In: Journal of Medicinal Chemistry. 37, 16, p. 2489-505 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1995
- Published
Crystallization and preliminary X-ray analysis of a PNA-DNA complex
Kastrup, Jette Sandholm Jensen, Pilgaard, M., Jørgensen, Flemming Steen, Nielsen, Peter E. & Rasmussen, H. B., 1995, In: FEBS Letters. 363, 1-2, p. 115-117 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1996
- Published
Update on protein structure prediction: Results of the 1995 IRBM workshop
Hubbard, T., Tramontano, A., Barton, G., Jones, D., Sippl, M., Valencia, A., Lesk, A., Moult, J., Rost, B., Sander, C., Schneider, R., Lahm, A., Leplae, R., Buta, C., Eisenstein, M., Fjellstrom, O., Floeckner, H., Grossmann, JG., Hansen, J., Citterich, MH. & 12 others, , 1996, In: Folding and Design. 1, 3, p. R55-R63Research output: Contribution to journal › Journal article › Research › peer-review
- 1997
- Published
Conformational analysis of six- and twelve-membered ring compounds by molecular dynamics
Christensen, I. T. & Jørgensen, Flemming Steen, 1997, In: Journal of Computer - Aided Molecular Design. 11, 4, p. 385-94 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular mechanics calculations of proteins. Comparison of different energy minimization strategies
Christensen, I. T. & Jørgensen, Flemming Steen, 1997, In: Journal of Biomolecular Structure & Dynamics. 15, 3, p. 473-88 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Substrate binding and catalytic mechanism in phospholipase C from Bacillus cereus. a molecular mechanics and molecular dynamics study
da Graça Thrige, D., Buur, J. R. & Jørgensen, Flemming Steen, 1997, In: Biopolymers. 42, 3, p. 319-36 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1999
- Published
Towards an understanding of drug resistance in malaria: three-dimensional structure of Plasmodium falciparum dihydrofolate reductase by homology building
Lemcke, T., Christensen, I. T. & Jørgensen, Flemming Steen, 1999, In: Bioorganic & Medicinal Chemistry. 7, 6, p. 1003-11 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2000
- Published
Structural differences of matrix metalloproteinases. Homology modeling and energy minimization of enzyme-substrate complexes
Terp, G. E., Christensen, I. T. & Jørgensen, Flemming Steen, 2000, In: Journal of Biomolecular Structure & Dynamics. 17, 6, p. 933-46 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2001
- Published
A new concept for multidimensional selection of ligand conformations (MultiSelect) and multidimensional scoring (MultiScore) of protein-ligand binding affinities
Terp, G. E., Johansen, B. N., Christensen, I. T. & Jørgensen, Flemming Steen, 2001, In: Journal of Medicinal Chemistry. 44, 14, p. 2333-43 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2002
- Published
Assessing the relative importance of the biophysical properties of amino acid substitutions associated with human genetic disease
Terp, B. N., Cooper, D. N., Christensen, I. T., Jørgensen, Flemming Steen, Bross, P. G., Gregersen, Niels Henrik & Krawczak, M., 2002, In: Human Mutation. 20, 2, p. 98-109 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural differences of matrix metalloproteinases with potential implications for inhibitor selectivity examined by the GRID/CPCA approach
Terp, G. E., Cruciani, G., Christensen, I. T. & Jørgensen, Flemming Steen, 2002, In: Journal of Medicinal Chemistry. 45, 13, p. 2675-84 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human peptide transporters: Therapeutic applications
Nielsen, C. U., Larsen, Birger Brodin, Jørgensen, Flemming Steen, Frøkjær, Sven & Steffansen, B., 1 Sep 2002, In: Expert Opinion on Therapeutic Patents. 12, 9, p. 1329-1350 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
Computeren kan forudsige lægemidlers omdannelse
Olsen, L., Bergmann, R. & Jørgensen, Flemming Steen, 2004, In: Lægemiddelforskning 2004.Research output: Contribution to journal › Journal article › Research
- Published
Docking and scoring of metallo-beta-lactamases inhibitors
Olsen, L., Pettersson, I., Hemmingsen, L., Adolph, H. & Jørgensen, Flemming Steen, 2004, In: Journal of Computer - Aided Molecular Design. 18, 4, p. 287-302 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation and comparison of 3D-QSAR CoMSIA models for CDK1, CDK5, and GSK-3 inhibition by paullones
Kunick, C., Lauenroth, K., Wieking, K., Xie, X., Schultz, C., Gussio, R., Zaharevitz, D., Leost, M., Meijer, L., Weber, A., Jørgensen, Flemming Steen & Lemcke, T., 2004, In: Journal of Medicinal Chemistry. 47, 1, p. 22-36 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Homology building as a means to define antigenic epitopes on dihydrofolate reductase (DHFR) from Plasmodium falciparum
Alifrangis, Michael, Christensen, I. T., Jørgensen, Flemming Steen, Rønn, A. M., Weng, J. E., Chen, M., Bygbjerg, Ib Christian, Sirawaraporn, W., Palarasah, Y. & Koch, C., 2004, In: Malaria Journal. 3, p. 16Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Isolation of a library of aromadendranes from Landolphia dulcis and its characterization using the VolSurf approach
Stærk, Dan, Skole, B., Jørgensen, Flemming Steen, Budnik, B. A., Ekpe, P. & Jaroszewski, J. W., 2004, In: Journal of Natural Products. 67, 5, p. 799-805 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural analysis of CYP2C9 and CYP2C5 and an evaluation of commonly used molecular modeling techniques
Afzelius, L., Raubacher, F., Karlén, A., Jørgensen, Flemming Steen, Andersson, T. B., Masimirembwa, C. M. & Zamora, I., 2004, In: Drug Metabolism and Disposition. 32, 11, p. 1218-29 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Conformational restrictions in ligand binding to the human intestinal di-/tripeptide transporter: implications for design of hPEPT1 targeted prodrugs
Våbenø, J., Nielsen, C. U., Steffansen, B., Lejon, T., Sylte, I., Jørgensen, Flemming Steen & Luthman, K., 2005, In: Bioorganic & Medicinal Chemistry. 13, 6, p. 1977-88 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Forudsigelser med hjælp fra det virtuelle rum
Andersen, R., Steffansen, B., Jørgensen, Flemming Steen & Nielsen, C. U., 2005, In: Lægemiddelforskning. p. 24-25Research output: Contribution to journal › Journal article › Communication
- Published
Prediction methods and databases within chemoinformatics: emphasis on drugs and drug candidates
Jónsdóttir, S. O., Jørgensen, Flemming Steen & Brunak, Søren, 2005, In: Bioinformatics. 21, 10, p. 2145-60 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Development of a QSAR model for binding of tripeptides and tripeptidomimetics to the human intestinal di-/tripeptide transporter hPEPT1
Andersen, R., Jørgensen, Flemming Steen, Olsen, L., Våbenø, J., Thorn, K., Nielsen, C. U. & Steffansen, B., 2006, In: Pharmaceutical Research. 23, 3, p. 483-92 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hvad har varme at gøre med lægemidler?
Olsen, L., Kasper, C., Kastrup, Jette Sandholm Jensen, Gajhede, Michael & Jørgensen, Flemming Steen, 2006, In: Lægemiddelforskning. p. 31-33Research output: Contribution to journal › Journal article › Communication
- Published
Identification of a gene on chromosome 12q22 uniquely overexpressed in chronic lymphocytic leukemia
Buhl, A. M., Jurlander, J., Jørgensen, Flemming Steen, Ottesen, A. M., Cowland, J. B., Gjerdrum, L. M., Hansen, B. V. & Leffers, H., 2006, In: Blood. 107, 7, p. 2904-11 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro evaluation of N-methyl amide tripeptidomimetics as substrates for the human intestinal di-/tri-peptide transporter hPEPT1
Andersen, R., Nielsen, C. U., Begtrup, M., Jørgensen, Flemming Steen, Larsen, Birger Brodin, Frøkjær, Sven & Steffansen, B., 2006, In: European Journal of Pharmaceutical Sciences. 28, 4, p. 325-35 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New leads of metallo-beta-lactamase inhibitors from structure-based pharmacophore design
Olsen, L., Jost, S., Adolph, H., Pettersson, I., Hemmingsen, Lars Bo Stegeager & Jørgensen, Flemming Steen, 2006, In: Bioorganic & Medicinal Chemistry. 14, 8, p. 2627-2635 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
Computational prediction of solubilizers' effect on partitioning
Høst, J., Christensen, I. T., Jørgensen, Flemming Steen, Frøkjær, Sven & Hovgaard, L., 2007, In: Internation Journal of Pharmaceutics. 329, 1-2, p. 46-52Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determination of protein conformation by isotopically labelled cross-linking and dedicated software: Application to the chaperone, calreticulin
Nielsen, T., Thaysen-Andersen, M., Larsen, N., Jørgensen, Flemming Steen, Houen, G. & Højrup, P., 2007, In: International Journal of Mass Spectrometry. 268, 2-3, p. 217-226Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Study on the binding of Thioflavin T to ß-sheet-rich and non-ß-sheet cavities
Jensen, M. G., Olsen, L., van de Weert, Marco, Flink, J. M., Frøkjær, Sven & Jørgensen, Flemming Steen, 2007, In: Journal of Structural Biology. 158, 3, p. 358-369Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
QSAR models for the human H+/peptide symporter, hPEPT1: Affinity prediction using alignment-independent descriptors
Larsen, S. B., Jørgensen, Flemming Steen & Olsen, L., 2008, In: Journal of Chemical Information and Modeling. 48, 1, p. 233-241Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Risiko for hjerteflimmer afsløres med computermodel
Taboureau, O., Brunak, S. & Jørgensen, Flemming Steen, 2008, In: Lægemiddelforskning. p. 31-33Research output: Contribution to journal › Journal article › Communication
- Published
Small angle X-ray scattering study of calreticulin reveals conformational plasticity
Toft, K. N., Larsen, N., Jørgensen, Flemming Steen, Højrup, P., Houen, G. & Vestergaard, Bente, 2008, In: BBA General Subjects. 1784, 9, p. 1265-1270Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Solvent diversity in polymorph screening
Allesø, M., van der Berg, Franciscus Winfried J, Cornett, Claus, Jørgensen, Flemming Steen, Halling-Sørensen, B., Lopez de Diego, H., Hovgaard, L., Aaltonen, J. & Rantanen, Jukka, 2008, In: Journal of Pharmaceutical Sciences. 97, 6, p. 2145-2159Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Classification of cytochrome P450 1A2 inhibitors and noninhibitors by machine learning techniques
Poongavanam, V., Taboureau, O., Oostenbrink, C., Vermeulen, N. P. E., Olsen, L. & Jørgensen, Flemming Steen, 2009, In: Drug Metabolism and Disposition. 37, 3, p. 658-664Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Computeren er medicinalkemikerens arbejdshest
Larsen, S. B., Olsen, L. & Jørgensen, Flemming Steen, 2009, In: Lægemiddelforskning. p. 7-9Research output: Contribution to journal › Journal article › Communication
- Published
Discovery of ligands for the human intestinal di-/tripeptide transporter (hPEPT1) using af QSAR-assisted virtual screening strategy
Larsen, S. B., Omkvist, D. H., Larsen, Birger Brodin, Nielsen, C. U., Steffansen, B., Olsen, L. & Jørgensen, Flemming Steen, 2009, In: ChemMedChem. 4, 9, p. 1439-1445Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Virtual screening and prediction of site of metabolism for cytochrome P450 1A2 ligands
Poongavanam, V., Hritz, J., Taboureau, O., Olsen, L., Jørgensen, Flemming Steen, Vermeulen, N. P. E. & Oostenbrink, C., 2009, In: Journal of Chemical Information and Modeling. 49, 1, p. 43-52Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
A diversity optimized combinatorial library for the identification of Fc-fragment binding ligands
Nielsen, A. L., Jørgensen, Flemming Steen, Olsen, L., Christensen, S. F., Benie, A. J., Bjørnholm, T. & St. Hilaire, P. M., 2010, In: Biopolymers. 94, 2, p. 192-205Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A quantitative structure-activity relationship for translocation of tripeptides via the human proton-coupled peptide transporter, hPEPT1 (SLC15A1)
Omkvist, D. H., Larsen, S. B., Nielsen, C. U., Steffansen, B., Olsen, L., Jørgensen, Flemming Steen & Larsen, Birger Brodin, 2010, In: The AAPS Journal. 12, 3, p. 385-396Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biostructure-based drug design
Jørgensen, Flemming Steen & Kastrup, Jette Sandholm Jensen, 2010, Textbook of drug design and discovery. Krogsgaard-Larsen, P., Strømgaard, K. & Madsen, U. (eds.). 4 ed. Boca Raton: CRC Press, p. 29-42Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education
- Published
Computational prediction of binding affinity for CYP1A2-ligand complexes using empirical free energy calculations
Poongavanam, V., Olsen, L., Jørgensen, Flemming Steen, Vermeulen, N. P. E. & Oostenbrink, C., 2010, In: Drug Metabolism and Disposition. 38, 8, p. 1347-1354Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Forbedret optagelse af lægemidler i organismen: computeren viser vejen
Larsen, S. B., Jørgensen, Flemming Steen & Olsen, L., 2010, In: Dansk Kemi. 91, 6/7, p. 18-20Research output: Contribution to journal › Journal article › Research
- Published
Homology modelling of the GABA transporter and analysis of tiagabine binding
Skovstrup, S., Taboureau, O., Bräuner, Hans & Jørgensen, Flemming Steen, 2010, In: ChemMedChem. 5, 7, p. 986-1000Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutational mapping and modeling of the binding site for (S)-citalopram in the human serotonin transporter
Andersen, J., Olsen, L., Hansen, K. B., Taboureau, O., Jørgensen, Flemming Steen, Jørgensen, A. M., Bang-Andersen, B., Egebjerg, J., Strømgaard, Kristian & Kristensen, Anders Skov, 2010, In: Journal of Biological Chemistry. 285, 3, p. 2051-2063Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Identification of CYP1A2 ligands by structure-based and ligand-based virtual screening
Poongavanam, V., Lastdrager, J., Oostenbrink, C., Commandeur, J. N. M., Vermeulen, N. P. E., Jørgensen, Flemming Steen & Olsen, L., 2011, In: MedChemComm. 2, 9, p. 853-859Research output: Contribution to journal › Journal article › Research › peer-review
- Published
G protein- and agonist-bound serotonin 5-HT2A receptor model activated by steered molecular dynamics simulations
Ísberg, V., Balle, T., Sander, T., Jørgensen, Flemming Steen & Gloriam, David E., 28 Feb 2011, In: Journal of Chemical Information and Modeling. 51, 2, p. 315-325Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In silico predictions of hERG channel blockers in drug discovery: from ligand-based and target-based approaches to systems chemical biology
Taboureau, O. & Jørgensen, Flemming Steen, Jun 2011, In: Combinatorial Chemistry & High Throughput Screening. 14, 5, p. 375-387Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
A robust force field based method for calculating conformational energies of charged drug-like molecules
Pøhlsgaard, J., Harpsøe, Kasper, Jørgensen, Flemming Steen & Olsen, L., 2012, In: Journal of Chemical Information and Modeling. 52, 2, p. 409-419Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A steered molecular dynamics study of binding and translocation processes in the GABA transporter
Skovstrup, S., David, L., Taboureau, O. & Jørgensen, Flemming Steen, 2012, In: P L o S One. 7, 6, p. e39360Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prediction of pH-dependent aqueous solubility of druglike molecules
Hansen, N. T., Kouskoumvekaki, I., Jørgensen, Flemming Steen, Brunak, Søren & Jónsdóttir, S. O., 2012, In: Journal of Chemical Information and Modeling. 46, 6, p. 2601-2609 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthesis and antiangiogenic activity of N-alkylated levamisole derivatives
Hansen, A. N., Bendiksen, C. D., Sylvest, L., Friis, T., Stærk, Dan, Jørgensen, Flemming Steen, Olsen, Christian Adam & Houen, G., 2012, In: P L o S One. 7, 9, 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
hERG classification model based on a combination of support vector machine method and GRIND descriptors
Li, Q., Jørgensen, Flemming Steen, Oprea, T., Brunak, Søren & Taboureau, O., 2012, In: Molecular Pharmaceutics. 5, 1, p. 117-127 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Use of density functional theory in drug metabolism studies
Rydberg, P., Jørgensen, Flemming Steen & Olsen, L., Feb 2014, In: Expert Opinion on Drug Metabolism & Toxicology. 10, 2, p. 215-27 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Design of prodrugs targeting the intestinal di/tri‐peptide transporter hPEPT1 (SLC15A1
Omkvist, D. H., Nielsen, C. U., Steffansen, B., Larsen, S. B., Olsen, L., Jørgensen, Flemming Steen & Larsen, Birger Brodin, 4 Apr 2014. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- 2015
- Published
Salt-bridge Swapping in the EXXERFXYY Motif of Proton Coupled Oligopeptide Transporters
Aduri, N. G., Prabhala, B. K., Ernst, H. A., Jørgensen, Flemming Steen, Olsen, L. & Mirza, Osman Asghar, 2015, In: The Journal of Biological Chemistry. 290, 50, p. 29931-29940 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Density functional theory study on the formation of reactive benzoquinone imines by hydrogen abstraction
Leth, R., Rydberg, P., Jørgensen, Flemming Steen & Olsen, L., 23 Mar 2015, In: Journal of Chemical Information and Modeling. 55, 3, p. 660-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prediction of cytochrome P450 mediated metabolism
Olsen, L., Oostenbrink, C. & Jørgensen, Flemming Steen, 6 May 2015, In: Advanced Drug Delivery Reviews. 86, p. 61-71 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Cytochrome P450 Mediated Drug Metabolism
Olsen, L., Jørgensen, Flemming Steen & Oostenbrink, C., 2016, New Horizons in Predictive Drug Metabolism and Pharmacokinetics. Wilson, A. G. E. (ed.). Cambridge: Royal Society of Chemistry, p. 66-78 13 p. (RSC Drug Discovery, Vol. 49).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Insights into regioselective metabolism of mefenamic acid by cytochrome P450 BM3 mutants through crystallography, docking, molecular dynamics, and free energy calculations
Capoferri, L., Leth, R., Ter Haar, E., Mohanty, A. K., Grootenhuis, P. D. J., Vottero, E., Commandeur, J. M. N., Vermeulen, N. P. E., Jørgensen, Flemming Steen, Olsen, L. & Geerke, D. P., Mar 2016, In: Proteins: Structure, Function, and Bioinformatics. 84, 3, p. 383-96 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enantioselective endocrine disrupting effects of omeprazole studied in the H295R cell assay and by molecular modeling
Sørensen, A. M., Hansen, C. H., Bonomo, S., Olsen, L., Jørgensen, Flemming Steen, Weisser, J. J., Kretschmann, A. C. & Styrishave, Bjarne, 19 Mar 2016, In: Toxicology in Vitro. 34, p. 71-80 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Promising Tools in Prostate Cancer Research: Selective Non-Steroidal Cytochrome P450 17A1 Inhibitors
Bonomo, S., Hansen, C. H., Petrunak, E. M., Scott, E. E., Styrishave, Bjarne, Jørgensen, Flemming Steen & Olsen, L., 12 Jul 2016, In: Scientific Reports. 6, 11 p., 29468.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Dissecting the Cytochrome P450 1A2- and 3A4-Mediated Metabolism of Aflatoxin B1 in Ligand and Protein Contributions
Bonomo, S., Jørgensen, Flemming Steen & Olsen, L., 24 Feb 2017, In: Chemistry: A European Journal. 23, 12, p. 2884-2893 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure-based optimisation of non-steroidal cytochrome P450 17A1 inhibitors
Larsen, M., Hansen, C. H., Rasmussen, T. B., Styrishave, Bjarne, Olsen, L. & Jørgensen, Flemming Steen, 28 Feb 2017, In: Chemical Communications. 53, 3118, 4 p., 3118.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The low binding affinity of D-serine at the ionotropic glutamate receptor GluD2 can be attributed to the hinge region
Tapken, D., Steffensen, T. B., Leth, R., Kristensen, L. B., Gerbola, A., Gajhede, Michael, Jørgensen, Flemming Steen, Olsen, L. & Kastrup, Jette Sandholm Jensen, 7 Apr 2017, In: Scientific Reports. 7, 12 p., 46145.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanism of Cytochrome P450 17A1-Catalyzed Hydroxylase and Lyase Reactions
Bonomo, S., Jørgensen, Flemming Steen & Olsen, L., 22 May 2017, In: Journal of Chemical Information and Modeling. 57, 5, p. 1123-1133 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aldehyde Oxidase: Reaction Mechanism and Prediction of Site of Metabolism
Montefiori, M., Jørgensen, Flemming Steen & Olsen, L., Aug 2017, In: ACS Omega. 2, 8, p. 4237-4244Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
The anti-epileptic drug lamotrigine inhibits the CYP17A1 lyase reaction in vitro
Munkboel, C. H., Christensen, L. R., Islin, J., Bonomo, S., Olsen, L., Jørgensen, Flemming Steen & Styrishave, Bjarne, Oct 2018, In: Biology of Reproduction. 99, 4, p. 888-897Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
An Optimized Screen Reduces the Number of GA Transporters and provides Insights into NPF Substrate Determinants
Wulff, N., Ernst, H. A., Jørgensen, M. E., Lambertz, S., Maierhofer, T., Belew, Zeinu Mussa, Crocoll, C., Motawia, M. S., Geiger, D., Jørgensen, Flemming Steen, Mirza, Osman Asghar & Nour-Eldin, Hussam Hassan, 2019, bioRxiv.Research output: Working paper › Preprint › Research
- Published
Structural analysis of Cytochrome P450 BM3 mutant M11 in complex with dithiothreitol
Frydenvang, Karla Andrea, Verkade-Vreeker, M. C. A., Dohmen, F., Commandeur, J. N. M., Rafiq, M., Mirza, Osman Asghar, Jørgensen, Flemming Steen & Geerke, D. P., 2019, In: PLoS ONE. 14, 5, 15 p., e0217292.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fast Methods for Prediction of Aldehyde Oxidase-Mediated Site-of-Metabolism
Montefiori, M., Lyngholm-Kjærby, C., Long, A., Olsen, L. & Jørgensen, Flemming Steen, 1 Jan 2019, In: Computational and Structural Biotechnology Journal. 17, p. 345-351 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular Dynamics Simulations Reveal the Proton:Peptide Coupling Mechanism in the Bacterial Proton-Coupled Oligopeptide Transporter YbgH
Aduri, N. G., Montefiori, M., Khalil, R., Gajhede, Michael, Jørgensen, Flemming Steen & Mirza, Osman Asghar, 31 Jan 2019, In: ACS Omega. 4, 1, p. 2040-2046 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Both Reactivity and Accessibility Are Important in Cytochrome P450 Metabolism: A Combined DFT and MD Study of Fenamic Acids in BM3 Mutants
Leth, R., Ercig, B., Olsen, L. & Jørgensen, Flemming Steen, 25 Feb 2019, In: Journal of Chemical Information and Modeling. 59, 2, p. 743-753 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SMARTCyp 3.0: enhanced cytochrome P450 site-of-metabolism prediction server
Olsen, L., Montefiori, M., Tran, K. P. & Jørgensen, Flemming Steen, 1 Sep 2019, In: Bioinformatics (Oxford, England). 35, 17, p. 3174-3175 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An Optimized Screen Reduces the Number of GA Transporters and Provides Insights Into Nitrate Transporter 1/Peptide Transporter Family Substrate Determinants
Wulff, N., Ernst, H. A., Jørgensen, M. E., Lambertz, S., Maierhofer, T., Belew, Zeinu Mussa, Crocoll, C., Motawie, Mohammed Saddik, Geiger, D., Jørgensen, Flemming Steen, Mirza, Osman Asghar & Nour-Eldin, Hussam Hassan, 3 Oct 2019, In: Frontiers in Plant Science. 10, 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Discovery of Novel Non-Steroidal Cytochrome P450 17A1 Inhibitors as Potential Prostate Cancer Agents
Wróbel, T. M., Rogova, O., Andersen, Kasper Langebjerg, Yadav, R., Brixius-Anderko, S., Scott, E. E., Olsen, L., Jørgensen, Flemming Steen & Björkling, Fredrik, 2020, In: International Journal of Molecular Sciences . 21, 14, p. 1-11 4868.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Biased cytochrome P450-mediated metabolism via small-molecule ligands binding P450 oxidoreductase
Jensen, S. B., Thodberg, S., Parween, S., Moses, M. E., Hansen, Cecilie Ida Cetti, Thomsen, J., Sletfjerding, M. B., Knudsen, C., Del Giudice, R., Lund, P. M., Castaño, P. R., Bustamante, Y. G., Velazquez, M. N. R., Jørgensen, Flemming Steen, Pandey, A. V., Laursen, Tomas, Møller, Birger Lindberg & Hatzakis, Nikos, 2021, In: Nature Communications. 12, 1, 14 p., 2260.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is the unique benzodiazepine structure interacting with CYP enzymes to affect steroid synthesis in vitro?
Johannsen, Malene Louise, Munkboel, C. H., Jørgensen, Flemming Steen & Styrishave, Bjarne, 2021, In: Journal of Steroid Biochemistry and Molecular Biology. 205, 10 p., 105765.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PTR2/POT/NPF transporters: what makes them tick?
Prabhala, B. K., Rahman, M., Nour-Eldin, Hussam Hassan, Jørgensen, Flemming Steen & Mirza, Osman Asghar, 2021, In: Advances in Protein Chemistry and Structural Biology. 123, p. 219-240 22 p.Research output: Contribution to journal › Review › Research › peer-review
- 2022
- Published
Itraconazole Reverts ABCB1-Mediated Docetaxel Resistance in Prostate Cancer
Lima, T. S., De Oliveira Souza, Luciano, Iglesias Gato, Diego, Elversang, J., Jørgensen, Flemming Steen, Kallunki, Tuula Anneli, Røder, Andreas, Brasso, K. & Moreira, José, 2022, In: Frontiers in Pharmacology. 13, 13 p., 869461.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthesis and Structure–Activity Relationships of Novel Non-Steroidal CYP17A1 Inhibitors as Potential Prostate Cancer Agents
Wróbel, T. M., Rogova, O., Sharma, K., Velazquez, M. N. R., Pandey, A. V., Jørgensen, Flemming Steen, Arendrup, Frederic Schrøder, Andersen, Kasper Langebjerg & Björkling, Fredrik, 2022, In: Biomolecules. 12, 2, 165.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Differences between the GluD1 and GluD2 receptors revealed by GluD1 X-ray crystallography, binding studies and molecular dynamics
Masternak, Magdalena, Koch, A., Laulumaa, S., Tapken, D., Hollmann, M., Jørgensen, Flemming Steen & Kastrup, Jette Sandholm Jensen, 2023, In: F E B S Journal. 290, 15, p. 3781-3801Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exploring the Potential of Sulfur Moieties in Compounds Inhibiting Steroidogenesis
Wróbel, T. M., Sharma, K., Mannella, I., Oliaro-Bosso, S., Nieckarz, P., Du Toit, T., Voegel, C. D., Rojas Velazquez, M. N., Yakubu, J., Matveeva, A., Therkelsen, S., Jørgensen, Flemming Steen, Pandey, A. V., Pippione, A. C., Lolli, M. L., Boschi, D. & Björkling, Fredrik, 2023, In: Biomolecules. 13, 9, 18 p., 1349.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Non-steroidal CYP17A1 Inhibitors: Discovery and Assessment
Wróbel, T. M., Jørgensen, Flemming Steen, Pandey, A. V., Grudzińska, A., Sharma, K., Yakubu, J. & Björkling, Fredrik, 2023, In: Journal of Medicinal Chemistry. 66, 10, p. 6542–6566Research output: Contribution to journal › Review › Research › peer-review
- Published
Polypharmacology-labeled molecular networking: An analytical technology workflow for accelerated identification of multiple bioactive constituents in complex extracts
Zhao, Yong, Gericke, Oliver, Li, T., Kjaerulff, Louise, Kongstad, Kenneth Thermann, Heskes, A. M., Møller, Birger Lindberg, Jørgensen, Flemming Steen, Venter, H., Coriani, S., Semple, S. J. & Stærk, Dan, 2023, In: Analytical Chemistry. 95, 9, p. 4381-4389 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2024
- Published
Effect of Essential Oil Components on the Activity of Steroidogenic Cytochrome P450
Sharma, K., Lanzilotto, A., Yakubu, J., Therkelsen, S., Vöegel, C. D., Du Toit, T., Jørgensen, Flemming Steen & Pandey, A. V., 2024, In: Biomolecules. 14, 2, 19 p., 203.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1302104
Most downloads
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2077
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Synthesis and antiangiogenic activity of N-alkylated levamisole derivatives
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
1974
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Forbedret optagelse af lægemidler i organismen: computeren viser vejen
Research output: Contribution to journal › Journal article › Research
Published -
1544
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Design of prodrugs targeting the intestinal di/tri‐peptide transporter hPEPT1 (SLC15A1
Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
Published