Henrik Franzyk

Henrik Franzyk

Associate Professor

Member of:


    1. 2022
    2. Published

      Simultaneous quantification of multiple RNA cargoes co-loaded into nanoparticle-based delivery systems

      Lokras, Abhijeet, Chakravarty, A., Rades, Thomas, Christensen, D., Franzyk, Henrik, Thakur, A. & Foged, Camilla, 2022, In: International Journal of Pharmaceutics. 626, 13 p., 122171.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Structural Determinants in the Staphylococcus aureus-Derived Phenol-Soluble Modulin α2 Peptide Required for Neutrophil Formyl Peptide Receptor Activation.

      Viklund, M., Fredriksson, J., Holdfeldt, A., Lind, S., Franzyk, Henrik, Dahlgren, C., Sundqvist, M. & Forsman, H., 2022, In: Journal of Immunology. 208, 7, p. 1632-1641

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. 2021
    5. Published

      Antibiotic Potentiation in Multidrug-Resistant Gram-Negative Pathogenic Bacteria by a Synthetic Peptidomimetic

      Harifi Mood, Elnaz, Goltermann, Lise, Brolin, C., Cavaco, L. M., Japoni Nejad, Alireza, Yavari, Niloofar, Frederiksen, N., Franzyk, Henrik & Nielsen, Peter E., 2021, In: ACS Infectious Diseases. 7, 8, p. 2152–2163

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Evaluation of 1H-Triazole-1-[N,N'-Bis(tert-butoxycarbonyl)]carboxamidine in Solution-Phase and On-Resin Guanidinylation

      Wester, A., Björkling, Fredrik & Franzyk, Henrik, 2021, In: The Journal of Organic Chemistry. 86, 21, p. 14371–14380

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      Inoculum effect of antimicrobial peptides

      Loffredo, M. R., Savini, F., Bobone, S., Casciaro, B., Franzyk, Henrik, Mangoni, M. L. & Stella, L., 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 21, 10 p., e2014364118.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      Neuroprotection Against NMDA-Induced Retinal Damage by Philanthotoxin-343 Involves Reduced Nitrosative Stress

      Mohamad, M. H. N., Abu, I. F., Fazel, M. F., Agarwal, R., Iezhitsa, I., Juliana, N., Mellor, I. R. & Franzyk, Henrik, 2021, In: Frontiers in Pharmacology. 12, 11 p., 798794.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      Optimized Synthesis of Fmoc/Boc-Protected PNA Monomers and their Assembly into PNA Oligomers.

      Shaikh, Ashif Yasin, Björkling, Fredrik, Nielsen, Peter E. & Franzyk, Henrik, 2021, In: European Journal of Organic Chemistry. 2021, 19, p. 2792-2801 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      Peptide/β-Peptoid Hybrids with Activity against Vancomycin-Resistant Enterococci: Influence of Hydrophobicity and Structural Features on Antibacterial and Hemolytic Properties

      Vestergaard, M., Skive, Bolette, Domraceva, I., Ingmer, Hanne & Franzyk, Henrik, 2021, In: International Journal of Molecular Sciences. 22, 11, 5617.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Peptide/β-Peptoid Hybrids with Ultrashort PEG-Like Moieties: Effects on Hydrophobicity, Antibacterial Activity and Hemolytic Properties

      Frederiksen, N., Louka, S., Mudaliar, C., Domraceva, I., Kreicberga, A., Pugovics, O., Żabicka, D., Tomczak, M., Wygoda, W., Björkling, Fredrik & Franzyk, Henrik, 2021, In: International Journal of Molecular Sciences. 22, 13, 17 p., 7041.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      Perfluoro-tert-butanol for selective on-resin detritylation: a mild alternative to traditionally used methods

      Wester, A., Hansen, A. M., Hansen, Paul Robert & Franzyk, Henrik, 2021, In: Amino Acids. 53, p. 1455–1466

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      Reversal of ABCG2/BCRP-mediated multidrug resistance by 5,3’,5’-trihydroxy-3,6,7,4’-tetramethoxyflavone isolated from the Australian desert plant Eremophila galeata Chinnock

      Petersen, M. J., Lund, X. L., Semple, S. J., Buirchell, B., Franzyk, Henrik, Gajhede, Michael, Kongstad, Kenneth Thermann, Stenvang, Jan & Stærk, Dan, 2021, In: Biomolecules. 11, 10, 19 p., 1534.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Targeting Toxins toward Tumors

      Franzyk, Henrik & Christensen, Søren Brøgger, 2021, In: Molecules. 26, 5, 23 p., 1292.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      The Effects of Structural Alterations in the Polyamine and Amino Acid Moieties of Philanthotoxins on Nicotinic Acetylcholine Receptor Inhibition in the Locust, Schistocerca gregaria

      Luck, V. L., Richards, D. P., Shaikh, Ashif Yasin, Franzyk, Henrik & Mellor, I. R., 2021, In: Molecules (Print Archive Edition). 26, 22, 11 p., 7007.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. 2020
    17. Published

      Alternating Cationic-Hydrophobic Peptide/Peptoid Hybrids: Influence of Hydrophobicity on Antibacterial Activity and Cell Selectivity

      Frederiksen, N., Hansen, Paul Robert, Zabicka, D., Tomczak, M., Urbas, M., Domraceva, I., Björkling, Fredrik & Franzyk, Henrik, 2020, In: ChemMedChem. 15, 24, p. 2544-2561

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Antidiabetic xanthones with α-glucosidase inhibitory activities from an endophytic Penicillium canescens

      Malik, A., Ardalani, H., Anam, S., McNair, Laura M., Kromphardt, K. J. K., Frandsen, R. J. N., Franzyk, Henrik, Stærk, Dan & Kongstad, Kenneth Thermann, 2020, In: Fitoterapia. 142, 8 p., 104522.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Barbadin selectively modulates FPR2-mediated neutrophil functions independent of receptor endocytosis

      Sundqvist, M., Holdfeldt, A., Wright, S. C., Møller, T. C., Siaw, E., Jennbacken, K., Franzyk, Henrik, Bouvier, M., Dahlgren, C. & Forsman, H., 2020, In: B B A - Molecular Cell Research. 1867, 12, 13 p., 118849.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      Facile Preparation of PNA-Peptide Conjugates with a Polar Maleimide-Thioether Linkage

      Hansen, A. M., Shaikh, Ashif Yasin & Franzyk, Henrik, 2020, Peptide Nucleic Acids: Methods and Protocols. P. E. N. (ed.). Humana Press, p. 97-118 22 p. (Methods in molecular biology (Clifton, N.J.), Vol. 2105).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    21. Published

      Fluorescent analogues of Human α-Calcitonin Gene-Related Peptide with vasodilator potency

      Zhu, J., Pedersen, M. D., Ahmed, L. S., Abdolalizadeh, B., Grell, A., Berg, Jais Oliver, Thulstrup, Peter Waaben, Franzyk, Henrik, Edvinsson, L., Sams, A., Sheykhzade, Majid & Hansen, Paul Robert, 2020, In: International Journal of Molecular Sciences (Online). 21, 4, p. 1-15 15 p., 1343.

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      Fmoc-Based Assembly of PNA Oligomers: Manual and Microwave-Assisted Automated Synthesis

      Shaikh, Ashif Yasin, Hansen, A. M. & Franzyk, Henrik, 2020, Peptide Nucleic Acids: Methods and Protocols. P. E. N. (ed.). Humana Press, p. 1-16 16 p. (Methods in molecular biology (Clifton, N.J.), Vol. 2105).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    23. Published

      In vivo Anti-inflammatory Activity of Lipidated Peptidomimetics Pam-(Lys-βNspe)6-NH2 and Lau-(Lys-βNspe)6-NH2 Against PMA-Induced Acute Inflammation

      Wu, B. C., Skovbakke, S. L., Masoudi, H., Hancock, R. E. W. & Franzyk, Henrik, 2020, In: Frontiers in Immunology. 11, 11 p., 2102.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Missing Selectivity of Targeted 4β-Phorbol Prodrugs Expected to be Potential Chemotherapeutics

      Tarvainen, I., Zimmermann, T., Heinonen, P., Jäntti, M. H., Yli-Kauhaluoma, J., Talman, V., Franzyk, Henrik, Tuominen, R. K. & Christensen, Søren Brøgger, 2020, In: A C S Medicinal Chemistry Letters. 11, 5, p. 671-677 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      Novel Cyclic Lipopeptide Antibiotics: Effects of Acyl Chain Length and Position

      Jensen, S. K., Thomsen, T. T., Oddo, A., Franzyk, Henrik, Løbner-Olesen, Anders & Hansen, Paul Robert, 2020, In: International Journal of Molecular Sciences . 21, 16, 18 p., 5829.

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. Published

      Optimizing the Intracellular Delivery of Therapeutic Anti-inflammatory TNF-α siRNA to Activated Macrophages Using Lipidoid-Polymer Hybrid Nanoparticles

      Lokras, Abhijeet, Thakur, A., Wadhwa, A., Thanki, K., Franzyk, Henrik & Foged, Camilla, 2020, In: Frontiers in Bioengineering and Biotechnology. 8, 14 p., 601155.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Published

      Philanthotoxin-343 attenuates retinal and optic nerve injury, and protects visual function in rats with N-methyl-D-aspartate-induced excitotoxicity

      Fazel, M. F., Abu, I. F., Mohamad, M. H. N., Agarwal, R., Iezhitsa, I., Bakar, N. S., Juliana, N., Mellor, I. R. & Franzyk, Henrik, 2020, In: PLoS ONE. 15, 7, 14 p., e0236450.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. 2019
    29. Published

      Peptide/Peptoid Hybrid Oligomers: The Influence of Hydrophobicity and Relative Side-Chain Length on Antibacterial Activity and Cell Selectivity

      Frederiksen, N., Hansen, Paul Robert, Björkling, Fredrik & Franzyk, Henrik, 4 Dec 2019, In: Molecules (Print Archive Edition). 24, 18 p., 4429.

      Research output: Contribution to journalJournal articleResearchpeer-review

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    ID: 1302063