Jan Stenvang
Associate Professor
Translational and Clinical Pharmacology
Jagtvej 160
2100 København Ø
- 2016
- Published
A phase II study of Epirubicin in oxaliplatin-resistant patients with metastatic colorectal cancer and TOP2A gene amplification
Tarpgaard, L. S., Qvortrup, C., Nygård, S. B., Nielsen, Signe Lykke, Andersen, D. R., Jensen, N. F., Stenvang, Jan, Detlefsen, S., Brünner, N. & Pfeiffer, P., 2016, In: B M C Cancer. 16, 5 p., 91.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of DNA topoisomerase I in three SN-38 resistant human colon cancer cell lines reveals a new pair of resistance-associated mutations
Jensen, N. F., Agama, K., Roy, A., Smith, D. H., Pfister, T. D., Rømer, M. U., Zhang, H., Doroshow, J. H., Knudsen, B. R., Stenvang, Jan, Brünner, N. & Pommier, Y., 2016, In: Journal of Experimental and Clinical Cancer Research (Online). 35, 14 p., 56.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Drug resistance in colorectal cancer cell lines is partially associated with aneuploidy status in light of profiling gene expression
Guo, J., Xu, S., Huang, X., Li, L., Zhang, C., Pan, Q., Ren, Z., Zhou, R., Ren, Y., Zi, J., Wu, L., Stenvang, Jan, Brünner, N., Wen, B. & Liu, S., 2016, In: Journal of Proteome Research. 15, 11, p. 4047–4059 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integrative analysis of miRNA and gene expression reveals regulatory networks in tamoxifen-resistant breast cancer
Joshi, T., Elias, D., Stenvang, Jan, Alves, C. M. L., Teng, F., Lyng, M. B., Lykkesfeldt, A. E., Brünner, N., Wang, J., Gupta, R., Workman, C. T. & Ditzel, H. J., 2016, In: OncoTarget. 7, 35, p. 57239-57253 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
miRNA profiling of circulating EpCAM(+) extracellular vesicles: promising biomarkers of colorectal cancer
Ostenfeld, M. S., Jensen, S. G., Jeppesen, D. K., Christensen, L., Thorsen, S. B., Stenvang, Jan, Hvam, M. L., Thomsen, A., Mouritzen, P., Rasmussen, M. H., Nielsen, H. J., Ørntoft, T. F. & Andersen, C. L., 2016, In: Journal of Extracellular Vesicles. 5, 14 p., 31488.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular characterization of irinotecan (SN-38) resistant human breast cancer cell lines
Jandu, H., Aluzaité, K., Fogh, L., Thrane, S. W., Noer, J. B., Proszek, J., Nguyen Do, K., Hansen, S. N., Damsgaard-Hansen, B., Nielsen, S. L., Stougaard, M., Knudsen, B. R., Moreira, J., Hamerlik, P., Gajjar, M., Smid, M., Martens, J., Foekens, J., Pommier, Y., Brünner, N. & 2 others, , 22 Jan 2016, In: B M C Cancer. 16, 13 p., 34.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibody validation and scoring guidelines for ABCG2 immunohistochemical staining in formalin-fixed paraffin-embedded colon cancer tissue
Karlsson, Camilla Cederbye, Palshof, J. A., Kuhlmann, Tine Plato, Duun-Henriksen, A. K., Linnemann, D., Stenvang, Jan, Nielsen, Dorte Lisbet, Brunner, N. & Viuff, B. M., 3 Jun 2016, In: Scientific Reports. 6, 16 p., 26997.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells
Hansen, S. N., Ehlers, Natasja Spring, Zhu, S., Thomsen, M. B. H., Nielsen, R. L., Liu, D., Wang, G., Hou, Y., Zhang, X., Xu, X., Bolund, L., Yang, H., Wang, J., Moreira, José, Ditzel, H. J., Brünner, N., Rasmussen, A. S., Stenvang, Jan & Gupta, R., 9 Jun 2016, In: B M C Genomics. 17, 15 p., 442.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Repurposing Cationic Amphiphilic Antihistamines for Cancer Treatment
Ellegaard, A., Dehlendorff, C., Vind, Anna Constance, Anand, A., Kristiansen, Luise Cederkvist, Petersen, N. H. T., Nylandsted, J., Stenvang, Jan, Mellemgaard, A., Osterlind, K., Friis, S. & Jaattela, Marja, Jul 2016, In: EBioMedicine. 9, p. 130-139 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
BMP-2 induces EMT and breast cancer stemness through Rb and CD44
Huang, P., Chen, A., He, W., Li, Z., Zhang, G., Liu, Z., Liu, G., Liu, X., He, S., Xiao, G., Huang, F., Stenvang, Jan, Brünner, N., Hong, A. & Wang, J., 2017, In: Cell Death Discovery. 3, 12 p., 17039.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metagenomic analysis of faecal microbiome as a tool towards targeted non-invasive biomarkers for colorectal cancer
Yu, J., Feng, Q., Wong, S. H., Zhang, D., Liang, Q. Y., Qin, Y., Tang, L., Zhao, H., Stenvang, J., Li, Y., Wang, X., Xu, X., Chen, N., Wu, W. K. K., Al-Aama, J., Nielsen, H. J., Kiilerich, P., Jensen, B. A. H., Yau, T. O., Lan, Z. & 19 others, , 2017, In: Gut. 66, p. 70-78 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Topoisomerase I copy number alterations as biomarker for irinotecan efficacy in metastatic colorectal cancer
Palshof, J. A., Høgdall, Estrid Vilma Solyom, Poulsen, T. S., Linnemann, D., Jensen, B. V., Pfeiffer, P., Tarpgaard, L. S., Brunner, N., Stenvang, Jan, Yilmaz, M. & Nielsen, Dorte Lisbet, 11 Jan 2017, In: BMC Cancer. 17, 10 p., 48.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Implications of ABCG2 Expression on Irinotecan Treatment of Colorectal Cancer Patients: A Review
Nielsen, Dorte Lisbet, Palshof, J. A., Bruenner, N., Stenvang, Jan & Viuff, B. M., Sep 2017, In: International Journal of Molecular Sciences (Online). 18, 9, 16 p., 1926.Research output: Contribution to journal › Review › Research › peer-review
- Published
Comprehensive genomic analysis of Oesophageal Squamous Cell Carcinoma reveals clinical relevance
Du, P., Huang, P., Huang, X., Li, X., Feng, Z., Li, F., Liang, S., Song, Y., Stenvang, Jan, Brünner, N., Yang, H., Ou, Y., Gao, Q. & Li, L., Dec 2017, In: Scientific Reports. 7, 9 p., 15324.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Therapeutic application of multipotent stem cells
Mirzaei, H., Sahebkar, A., Sichani, L. S., Moridikia, A., Nazari, S., Sadri Nahand, J., salehi, H., Stenvang, Jan, Masoudifar, A., Mirzaei, H. R. & Jaafari, M. R., 2018, In: Journal of Cellular Physiology. 233, 4, p. 2815–2823Research output: Contribution to journal › Review › Research › peer-review
- Published
State of the art in microRNA as diagnostic and therapeutic biomarkers in chronic lymphocytic leukemia
Mirzaei, H., Fathullahzadeh, S., Khanmohammadi, R., Darijani, M., Momeni, F., Masoudifar, A., Goodarzi, M., Mardanshah, O., Stenvang, Jan, Jaafari, M. R. & Mirzaei, H. R., Feb 2018, In: Journal of Cellular Physiology. 233, 2, p. 888-900 13 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
lncRNA profile study reveals the mRNAs and lncRNAs associated with docetaxel resistance in breast cancer cells
Huang, P., Li, F., Li, L., You, Y., Luo, S., Dong, Z., Gao, Q., Wu, S., Brünner, N. & Stenvang, Jan, 1 Dec 2018, In: Scientific Reports. 8, 1, 17970.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Metallopeptidase Inhibitor 1 (TIMP-1) promotes receptor tyrosine kinase c-Kit signaling in colorectal cancer
Nordgaard, C., Doll, S., Matos, A. L. D. S. A., Høeberg, M., Kazi, J. U., Friis, S., Stenvang, Jan, Rönnstrand, L., Mann, Matthias & Moreira, José, 2019, In: Molecular Oncology. 13, 12, p. 2646-2662Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Two open-label, single arm, non-randomized phase II studies of irinotecan for the treatment of metastatic breast cancer in patients with increased copy number of the topoisomerase i gene
Kümler, I., Balslev, E., Stenvang, Jan, Brünner, N., Ejlertsen, Bent Laursen, Jakobsen, E. H. & Nielsen, D. L., Jun 2019, In: BMC Cancer. 19, 5 p., 573.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gel-Based Proteomics of Clinical Samples Identifies Potential Serological Biomarkers for Early Detection of Colorectal Cancer
Thorsen, S. F., Gromova, I., Christensen, I. J., Fredriksson, S., Andersen, C. L., Nielsen, H. J., Stenvang, Jan & Moreira, José, Dec 2019, In: International Journal of Molecular Sciences (Online). 20, 19 p., 6082.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
ABCG2 Protein Levels and Association to Response to First-Line Irinotecan-Based Therapy for Patients with Metastatic Colorectal Cancer
Palshof, J. A., Cederbye, C. N., Hgdall, E. V. S., Poulsen, T. S., Linnemann, D., Nygaard, S. B., Stenvang, Jan, Christensen, I. J., Jensen, B. V., Pfeiffer, P., Brunner, N., Yilmaz, M., Viuff, B. M. & Nielsen, Dorte Lisbet, 2020, In: International Journal of Molecular Sciences. 21, 14, 13 p., 5027.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An Explorative Analysis of ABCG2/TOP-1 mRNA Expression as a Biomarker Test for FOLFIRI Treatment in Stage III Colon Cancer Patients: Results from Retrospective Analyses of the PETACC-3 Trial
Stenvang, Jan, Budinská, E., van Cutsem, E., Bosman, F., Popovici, V. & Brünner, N., 2020, In: Cancers. 12, 4, 12 p., 977.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of resistance to a recombinant hexameric Fas-ligand (APO010) in human cancer cell lines
Jandu, H., Nielsen, A., Brunner, N., Hansen, A., Knudsen, S., Stenvang, Jan & Jensen, P. B., 2020, In: Experimental Hematology. 87, p. 33-41Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Four phase 1 trials to evaluate the safety and pharmacokinetic profile of single and repeated dosing of SCO-101 in adult male and female volunteers
Bergmann, T. K., Stage, T. B., Stenvang, Jan, Christophersen, P., Jacobsen, T. A., Roest, N. L., Vestlev, P. M. & Brunner, N., 2020, In: Basic & Clinical Pharmacology & Toxicology. 127, 4, p. 329-337Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacodynamic modelling reveals synergistic interaction between docetaxel and SCO-101 in a docetaxel-resistant triple negative breast cancer cell line
Nøhr-Nielsen, A., Bagger, Sofie Morsing, Brünner, N., Stenvang, Jan & Lund, Trine Meldgaard, 2020, In: European Journal of Pharmaceutical Sciences. 148, 10 p., 105315.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 12922
Most downloads
-
1963
downloads
MicroRNAs, epigenetics and disease
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
1687
downloads
Measuring ERCC1 protein expression in cancer specimens: validation of a novel antibody
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
1394
downloads
Progesterone receptor isoform A may regulate the effects of neoadjuvant aglepristone in canine mammary carcinoma
Research output: Contribution to journal › Journal article › Research › peer-review
Published