Jesper M. Mathiesen

Jesper M. Mathiesen

Associate Professor


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  1. Published

    Structural insights into the activation of metabotropic glutamate receptors

    Koehl, A., Hu, H., Feng, D., Sun, B., Zhang, Y., Robertson, M. J., Chu, M., Kobilka, T. S., Laeremans, T., Steyaert, J., Tarrasch, J., Dutta, S., Fonseca, R., Weis, W. I., Mathiesen, Jesper M., Skiniotis, G. & Kobilka, B. K., 7 Feb 2019, In: Nature. 566, 7742, p. 79-84

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Structural Insights into the Process of GPCR-G Protein Complex Formation

    Liu, X., Xu, X., Hilger, D., Aschauer, P., Tiemann, J. K. S., Du, Y., Liu, H., Hirata, K., Sun, X., Guixa-Gonzalez, R., Mathiesen, Jesper M., Hildebrand, P. W. & Kobilka, B. K., 16 May 2019, In: Cell. 177, 5, p. P1243-1251

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Crystal structure of the μ-opioid receptor bound to a morphinan antagonist

    Manglik, A., Kruse, A. C., Kobilka, T. S., Thian, F. S., Mathiesen, Jesper M., Sunahara, R. K., Pardo, L., Weis, W. I., Kobilka, B. K. & Granier, S., 17 May 2012, In: Nature. 485, 7398, p. 321-326 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Identification of indole derivatives exclusively interfering with a G protein-independent signaling pathway of the prostaglandin D2 receptor CRTH2

    Mathiesen, Jesper M., Ulven, Trond, Martin, L., Gerlach, L., Heinemann, A. & Kostenis, E., 2005, In: Molecular Pharmacology. 68, 2, p. 393-402 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    On the mechanism of interaction of potent, surmountable and insurmountable antagonists with the prostaglandin D2 receptor CRTH2

    Mathiesen, Jesper M., Christopoulos, A., Ulven, Trond, Royer, J. F., Campillo, M., Heinemann, A., Pardo, L. & Kostenis, E., 2006, In: Molecular Pharmacology. 69, 4, p. 1441-1453 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    cAMP biosensors applied in molecular pharmacological studies of G protein-coupled receptors

    Mathiesen, Jesper M., Vedel, L. & Bräuner, Hans, 2013, In: Methods in Enzymology. 522, p. 191-207 17 p.

    Research output: Contribution to journal › Journal article › Research

  7. Published

    Positive allosteric modulation of the human metabotropic glutamate receptor 4 (hmGluR4) by SIB-1893 and MPEP

    Mathiesen, Jesper M., Svendsen, N., Bräuner, Hans, Thomsen, C. & Ramirez, M. T., Mar 2003, In: British Journal of Pharmacology. 138, 6, p. 1026-30

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The metabotropic glutamate receptor 4 is internalized and desensitized upon protein kinase C activation

    Mathiesen, Jesper M. & Ramirez, M. T., 1 Jun 2006, In: British Journal of Pharmacology. 148, 3, p. 279-290 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Allosteric modulators of group III metabotropic glutamate receptors as novel therapeutics

    Mathiesen, Jesper M. & Teresa Ramirez, M., 19 Apr 2016, Allosteric Receptor Modulation in Drug Targeting. CRC Press, p. 207-234 28 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  10. Published

    Binding Mode of a Novel MPEP-Derived Metabotropic Glutamate Receptor Subtype 5 (mGluR5) NAM, 1,3-Bis(pyridin-2-ylethynyl)Benzene

    Molck, C., Harpsøe, Kasper, Gloriam, David E., Kaae, B. H., Jimenez, H. N., Uberti, M. A., Topiol, S., Clausen, Rasmus Prætorius, Madsen, Ulf, Nielsen, S. M., Mathiesen, Jesper M. & Bräuner, Hans, Sep 2011, In: Current Neuropharmacology. 9, p. 43-43

    Research output: Contribution to journal › Conference abstract in journal › Research

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