Ole Thastrup

Ole Thastrup

Emeritus

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    Jagtvej 160

    2100 København Ø

    Mobile: +4522115399

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  1. A novel tumour promoter, thapsigargin, transiently increases cytoplasmic free Ca2+ without generation of inositol phosphates in NG115-401L neuronal cells

    Jackson, T. R., Patterson, S. I., Thastrup, Ole & Hanley, M. R., 1988, In: Biochemical Journal. 253, 1, p. 81-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Activation of calcium entry by the tumor promoter thapsigargin in parotid acinar cells. Evidence that an intracellular calcium pool and not an inositol phosphate regulates calcium fluxes at the plasma membrane

    Takemura, H., Hughes, A. R., Thastrup, Ole & Putney, J. W., 1989, In: Journal of Biological Chemistry. 264, 21, p. 12266-71 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Biochemical and ultrastructural studies suggest that the effects of thapsigargin on human platelets are mediated by changes in intracellular calcium but not by intracellular histamine

    Saxena, S. P., McNicol, A., Becker, A. B., Brandes, L. J., Thastrup, Ole & Gerrard, J. M., 1992, In: Thrombosis and Haemostasis. 68, 6, p. 714-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Ca2+ transients and Mn2+ entry in human neutrophils induced by thapsigargin

    Foder, B., Scharff, O. & Thastrup, Ole, 1989, In: Cell Calcium. 10, 7, p. 477-90 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Calcium efflux across the plasma membrane of rat parotid acinar cells is unaffected by receptor activation or by the microsomal calcium ATPase inhibitor, thapsigargin

    Takemura, H., Thastrup, Ole & Putney, J. W., 1990, In: Cell Calcium. 11, 1, p. 11-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Changes in intracellular cAMP reported by a Redistribution assay using a cAMP-dependent protein kinase-green fluorescent protein chimera

    Almholt, K., Tullin, S., Skyggebjerg, O., Scudder, K., Thastrup, Ole & Terry, R., 2004, In: Cellular Signalling. 16, 8, p. 907-20 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Characteristics of stably expressed human dopamine D1a and D1b receptors: atypical behavior of the dopamine D1b receptor

    Pedersen, U. B., Norby, B., Jensen, Anders A., Schiødt, M., Hansen, A., Suhr-Jessen, P., Scheideler, M., Thastrup, Ole & Andersen, P. H., 1994, In: European Journal of Pharmacology. 267, 1, p. 85-93 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Characterization of genetic intratumor heterogeneity in colorectal cancer and matching patient-derived spheroid cultures

    Árnadóttir, S. S., Jeppesen, M., Lamy, P., Bramsen, J. B., Nordentoft, I., Knudsen, M., Vang, S., Madsen, M. R., Thastrup, Ole, Thastrup, J. & L Andersen, C., Jan 2018, In: Molecular Oncology. 12, p. 132-147

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Chemical synthesis on SU-8

    Qvortrup, K., Taveras, K., Thastrup, Ole & Nielsen, T., 2011, In: Chemical Communications. 47, 4, p. 1309-11 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Comparison of the action of calcium antagonists on basophil histamine release

    Bindslev Jensen, C., Clementsen, P., Stahl Skov, P., Svendsen, U. G., Thastrup, Ole & Norn, S., 1987, In: Allergy: European Journal of Allergy and Clinical Immunology. 42, 6, p. 441-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Complexity of the influence of gangliosides on histamine release from human basophils and rat mast cells

    Jensen, C., Svendsen, U. G., Thastrup, Ole, Stahl Skov, P., Leon, A. & Norn, S., 1987, In: Agents and Actions. 21, 1-2, p. 79-82 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Coronary vasodilatory, spasmolytic and cAMP-Phosphodiesterase inhibitory properties of dihydropyranocoumarins and dihydrofuranocoumarins

    Thastrup, Ole, Fjalland, B. & Lemmich, J., 1982, In: Planta Medica. 45, 3, p. 131

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Coronary vasodilatory, spasmolytic and cAMP-phosphodiesterase inhibitory properties of dihydropyranocoumarins and dihydrofuranocoumarins

    Thastrup, Ole, Fjalland, B. & Lemmich, J., 1983, In: Acta pharmacologica et Toxicologica. 52, 4, p. 246-53 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Demonstration of two forms of calcium pumps by thapsigargin inhibition and radioimmunoblotting in platelet membrane vesicles

    Papp, B., Enyedi, A., Kovács, T., Sarkadi, B., Wuytack, F., Thastrup, Ole, Gárdos, G., Bredoux, R., Levy-Toledano, S. & Enouf, J., 1991, In: Journal of Biological Chemistry. 266, 22, p. 14593-6 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Effect of thapsigargin on cytoplasmic Ca2+ and proliferation of human lymphocytes in relation to AIDS

    Scharff, O., Foder, B., Thastrup, Ole, Hofmann, B., Møller, J., Ryder, L. P., Jacobsen, K. D., Langhoff, E., Dickmeiss, E. & Christensen, Søren Brøgger, 1988, In: BBA General Subjects. 972, 3, p. 257-64 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Effects of MeCh, thapsigargin, and La3+ on plasmalemmal and intracellular Ca2+ transport in lacrimal acinar cells

    Kwan, C. Y., Takemura, H., Obie, J. F., Thastrup, Ole & Putney, J. W., 1990, In: American Journal of Physiology (Consolidated). 258, 6 Pt 1, p. C1006-15

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Effects of thapsigargin in isolated rat thoracic aorta

    Mikkelsen, E. O., Thastrup, Ole & Christensen, Søren Brøgger, 1988, In: Pharmacology & Toxicology. 62, 1, p. 7-11 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Excitation wave propagation as a possible mechanism for signal transmission in pancreatic islets of Langerhans

    Aslanidi, O. V., Mornev, O. A., Skyggebjerg, O., Arkhammar, P., Thastrup, Ole, Sørensen, M. P., Christiansen, P. L., Conradsen, K. & Scott, A. C., 2001, In: Biophysical Journal. 80, 3, p. 1195-209 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Exclusion of known protease-activated receptors in factor VIIa-induced signal transduction

    Petersen, L. C., Thastrup, Ole, Hagel, G., Sørensen, B. B., Freskgård, P. O., Rao, L. V. & Ezban, M., 2000, In: Thrombosis and Haemostasis. 83, 4, p. 571-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Flow injection microscopy: a novel tool for the study of cellular response and drug discovery

    Ruzicka, J., Baxter, P. J., Thastrup, Ole & Scudder, K., 1996, In: Analyst. 121, 7, p. 945-50 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Functional identification and monitoring of individual alpha and beta cells in cultured mouse islets of Langerhans

    Hjortoe, G. M., Hagel, G. M., Terry, B. R., Thastrup, Ole & Arkhammar, P. O. G., 2004, In: Acta Diabetologica. 41, 4, p. 185-93 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. How do inositol phosphates regulate calcium signaling?

    Putney, J. W., Takemura, H., Hughes, A. R., Horstman, D. A. & Thastrup, Ole, 1989, In: F A S E B Journal. 3, 8, p. 1899-905 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Identifying a compound modifying a cellular response, comprises attaching cells having a reporter system onto solid supports, releasing a library member, screening and identifying target cells

    Hagel, G., Thastrup, Ole, Meldal, Morten Peter, Norrild, J. C., Hentzer, M., Norrild, J. & Diness, Frederik, 29 Dec 2011, IPC No. G01N 35/ 00 A N, Patent No. US2011319274, Priority date 25 May 2005, Priority No. WO2005DK00348

    Research output: Patent

  24. In situ imaging of agonist-sensitive calcium pools in AR4-2J pancreatoma cells. Evidence for an agonist- and inositol 1,4,5-trisphosphate-sensitive calcium pool in or closely associated with the nuclear envelope

    Glennon, M. C., Bird, G. S., Takemura, H., Thastrup, Ole, Leslie, B. A. & Putney, J. W., 1992, In: Journal of Biological Chemistry. 267, 35, p. 25568-75 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Influence of nimodipine, verapamil and lanthanum on histamine release from human basophils: effect of pretreatment with sialidase

    Jensen, C. B., Thastrup, Ole, Norn, S. & Skov, P. S., 1987, In: Pharmacology & Toxicology. 60, 3, p. 214-6 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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