Ole Thastrup
Emeritus
Administration and Operations
Jagtvej 160
2100 København Ø
- 2018
- Published
Characterization of genetic intratumor heterogeneity in colorectal cancer and matching patient-derived spheroid cultures
Árnadóttir, S. S., Jeppesen, M., Lamy, P., Bramsen, J. B., Nordentoft, I., Knudsen, M., Vang, S., Madsen, M. R., Thastrup, Ole, Thastrup, J. & L Andersen, C., Jan 2018, In: Molecular Oncology. 12, p. 132-147Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Short-term spheroid culture of primary colorectal cancer cells as an in vitro model for personalizing cancer medicine
Jeppesen, M., Hagel, G., Glenthoj, A., Vainer, B., Ibsen, Per Holger, Harling, H., Thastrup, Ole, Jørgensen, Lars Nannestad & Thastrup, J., 2017, In: PLOS ONE. 12, 9, 19 p., e0183074.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Identifying a compound modifying a cellular response, comprises attaching cells having a reporter system onto solid supports, releasing a library member, screening and identifying target cells
Hagel, G., Thastrup, Ole, Meldal, Morten Peter, Norrild, J. C., Hentzer, M., Norrild, J. & Diness, Frederik, 29 Dec 2011, IPC No. G01N 35/ 00 A N, Patent No. US2011319274, Priority date 25 May 2005, Priority No. WO2005DK00348Research output: Patent
Chemical synthesis on SU-8
Qvortrup, K., Taveras, K., Thastrup, Ole & Nielsen, T., 2011, In: Chemical Communications. 47, 4, p. 1309-11 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
Changes in intracellular cAMP reported by a Redistribution assay using a cAMP-dependent protein kinase-green fluorescent protein chimera
Almholt, K., Tullin, S., Skyggebjerg, O., Scudder, K., Thastrup, Ole & Terry, R., 2004, In: Cellular Signalling. 16, 8, p. 907-20 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
Functional identification and monitoring of individual alpha and beta cells in cultured mouse islets of Langerhans
Hjortoe, G. M., Hagel, G. M., Terry, B. R., Thastrup, Ole & Arkhammar, P. O. G., 2004, In: Acta Diabetologica. 41, 4, p. 185-93 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2001
Excitation wave propagation as a possible mechanism for signal transmission in pancreatic islets of Langerhans
Aslanidi, O. V., Mornev, O. A., Skyggebjerg, O., Arkhammar, P., Thastrup, Ole, Sørensen, M. P., Christiansen, P. L., Conradsen, K. & Scott, A. C., 2001, In: Biophysical Journal. 80, 3, p. 1195-209 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2000
Exclusion of known protease-activated receptors in factor VIIa-induced signal transduction
Petersen, L. C., Thastrup, Ole, Hagel, G., Sørensen, B. B., Freskgård, P. O., Rao, L. V. & Ezban, M., 2000, In: Thrombosis and Haemostasis. 83, 4, p. 571-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Separation of the glucose-stimulated cytoplasmic and mitochondrial NAD(P)H responses in pancreatic islet beta cells
Patterson, G. H., Knobel, S. M., Arkhammar, P., Thastrup, Ole & Piston, D. W., 2000, In: Proceedings of the National Academy of Sciences of the United States of America. 97, 10, p. 5203-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1999
Simultaneous visualization of the translocation of protein kinase Calpha-green fluorescent protein hybrids and intracellular calcium concentrations
Almholt, K., Arkhammar, P. O., Thastrup, Ole & Tullin, S., 1999, In: Biochemical Journal. 337 ( Pt 2), p. 211-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1998
Signal transduction via the mitogen-activated protein kinase pathway induced by binding of coagulation factor VIIa to tissue factor
Poulsen, L. K., Jacobsen, N., Sørensen, B. B., Bergenhem, N. C., Kelly, J. D., Foster, D. C., Thastrup, Ole, Ezban, M. & Petersen, L. C., 1998, In: Journal of Biological Chemistry. 273, 11, p. 6228-32 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1996
Flow injection microscopy: a novel tool for the study of cellular response and drug discovery
Ruzicka, J., Baxter, P. J., Thastrup, Ole & Scudder, K., 1996, In: Analyst. 121, 7, p. 945-50 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1995
- Published
Structure-activity relationships of analogues of thapsigargin modified at O-11 and O-12
Nielsen, S. F., Thastrup, Ole, Pedersen, R., Olsen, C. E. & Christensen, Søren Brøgger, 1995, In: Journal of Medicinal Chemistry. 38, 2, p. 272-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1994
- Published
Characteristics of stably expressed human dopamine D1a and D1b receptors: atypical behavior of the dopamine D1b receptor
Pedersen, U. B., Norby, B., Jensen, Anders A., Schiødt, M., Hansen, A., Suhr-Jessen, P., Scheideler, M., Thastrup, Ole & Andersen, P. H., 1994, In: European Journal of Pharmacology. 267, 1, p. 85-93 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thapsigargin: a novel molecular probe for studying intracellular calcium release and storage
Thastrup, Ole, Dawson, A. P., Scharff, O., Foder, B., Cullen, P. J., Drøbak, B. K., Bjerrum, P. J., Christensen, Søren Brøgger & Hanley, M. R., 1994, In: Agents and Actions. 43, 3-4, p. 187-93 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1993
- Published
Structure-activity relationships of thapsigargin
Nielsen, S. F., Andersen, A., Olsen, C. E., Treimann, M., Thastrup, Ole & Christensen, Søren Brøgger, 1 Dec 1993, In: Planta Medica. 59, 7 SUPPL., p. A678-A679Research output: Contribution to journal › Journal article › Research › peer-review
- 1992
- Published
Biochemical and ultrastructural studies suggest that the effects of thapsigargin on human platelets are mediated by changes in intracellular calcium but not by intracellular histamine
Saxena, S. P., McNicol, A., Becker, A. B., Brandes, L. J., Thastrup, Ole & Gerrard, J. M., 1992, In: Thrombosis and Haemostasis. 68, 6, p. 714-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
In situ imaging of agonist-sensitive calcium pools in AR4-2J pancreatoma cells. Evidence for an agonist- and inositol 1,4,5-trisphosphate-sensitive calcium pool in or closely associated with the nuclear envelope
Glennon, M. C., Bird, G. S., Takemura, H., Thastrup, Ole, Leslie, B. A. & Putney, J. W., 1992, In: Journal of Biological Chemistry. 267, 35, p. 25568-75 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Mechanisms of activated Ca2+ entry in the rat pancreatoma cell line, AR4-2J
Bird, G. S., Takemura, H., Thastrup, Ole, Putney, J. W. & Menniti, F. S., 1992, In: Cell Calcium. 13, 1, p. 49-58 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On the botanical distribution of chiral forms of gossypol
Jaroszewski, J. W., Strøm-Hansen, T., Hansen, S. H., Thastrup, Ole & Kofod, H., 1992, In: Planta Medica. 58, 5, p. 454-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The molluscicidal activity of coumarins from Ethulia conyzoides and of dicumarol
Kady, M. M., Brimer, L., Furu, Peter, Lemmich, E., Nielsen, H. M., Thiilborg, S. T., Thastrup, Ole & Christensen, Søren Brøgger, 1992, In: Planta Medica. 58, 4, p. 334-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1991
Demonstration of two forms of calcium pumps by thapsigargin inhibition and radioimmunoblotting in platelet membrane vesicles
Papp, B., Enyedi, A., Kovács, T., Sarkadi, B., Wuytack, F., Thastrup, Ole, Gárdos, G., Bredoux, R., Levy-Toledano, S. & Enouf, J., 1991, In: Journal of Biological Chemistry. 266, 22, p. 14593-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
Mobilization of calcium by inositol trisphosphates from permeabilized rat parotid acinar cells. Evidence for translocation of calcium from uptake to release sites within the inositol 1,4,5-trisphosphate- and thapsigargin-sensitive calcium pool
Menniti, F. S., Bird, G. S., Takemura, H., Thastrup, Ole, Potter, B. V. & Putney, J. W., 1991, In: Journal of Biological Chemistry. 266, 21, p. 13646-53 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of inositol (1,4,5)trisphosphate in epidermal growth factor-induced Ca2+ signaling in A431 cells
Hughes, A. R., Bird, G. S., Obie, J. F., Thastrup, Ole & Putney, J. W., 1991, In: Molecular Pharmacology. 40, 2, p. 254-62 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Stimulatory effect of thapsigargin, a non-TPA-type tumor promoter, on arachidonic acid metabolism in the murine keratinocyte line HEL30 and on epidermal cell proliferation in vivo as compared to the effects of phorbol ester TPA
Marks, F., Hanke, B., Thastrup, Ole & Fürstenberger, G., 1991, In: Carcinogenesis. 12, 8, p. 1491-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 343169660
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Short-term spheroid culture of primary colorectal cancer cells as an in vitro model for personalizing cancer medicine
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
148
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Characterization of genetic intratumor heterogeneity in colorectal cancer and matching patient-derived spheroid cultures
Research output: Contribution to journal › Journal article › Research › peer-review
Published