Ole Thastrup

Ole Thastrup

Emeritus

  • Administration and Operations

    Jagtvej 160

    2100 København Ø

    Mobile: +4522115399

  1. 1982
  2. Published

    Coronary vasodilatory, spasmolytic and cAMP-Phosphodiesterase inhibitory properties of dihydropyranocoumarins and dihydrofuranocoumarins

    Thastrup, Ole, Fjalland, B. & Lemmich, J., 1982, In: Planta Medica. 45, 3, p. 131

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 1983
  4. Published

    Coronary vasodilatory, spasmolytic and cAMP-phosphodiesterase inhibitory properties of dihydropyranocoumarins and dihydrofuranocoumarins

    Thastrup, Ole, Fjalland, B. & Lemmich, J., 1983, In: Acta pharmacologica et Toxicologica. 52, 4, p. 246-53 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 1985
  6. Published

    Inhibition of human platelet aggregation by dihydropyrano- and dihydrofuranocoumarins, a new class of cAMP-phosphodiesterase inhibitors

    Thastrup, Ole, Knudsen, J. B., Lemmich, J. & Winther, K., 1985, In: Biochemical Pharmacology. 34, 12, p. 2137-40 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The ability of thapsigargin and thapsigargicin to activate cells involved in the inflammatory response

    Ali, H., Christensen, Søren Brøgger, Foreman, J. C., Pearce, F. L., Piotrowski, W. & Thastrup, Ole, 1985, In: British Journal of Pharmacology. 85, 3, p. 705-12 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 1987
  9. Comparison of the action of calcium antagonists on basophil histamine release

    Bindslev Jensen, C., Clementsen, P., Stahl Skov, P., Svendsen, U. G., Thastrup, Ole & Norn, S., 1987, In: Allergy: European Journal of Allergy and Clinical Immunology. 42, 6, p. 441-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Complexity of the influence of gangliosides on histamine release from human basophils and rat mast cells

    Jensen, C., Svendsen, U. G., Thastrup, Ole, Stahl Skov, P., Leon, A. & Norn, S., 1987, In: Agents and Actions. 21, 1-2, p. 79-82 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Influence of nimodipine, verapamil and lanthanum on histamine release from human basophils: effect of pretreatment with sialidase

    Jensen, C. B., Thastrup, Ole, Norn, S. & Skov, P. S., 1987, In: Pharmacology & Toxicology. 60, 3, p. 214-6 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Inhibition of basophil histamine release by gangliosides. Further studies on the significance of cell membrane sialic acid in the histamine release process

    Jensen, C., Norn, S., Thastrup, Ole, Dahl, B. T. & Skov, P. S., 1987, In: Allergy: European Journal of Allergy and Clinical Immunology. 42, 1, p. 51-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Membrane sialic acid influences basophil histamine release by interfering with calcium dependence

    Jensen, C., Norn, S., Skov, P. S., Dahl, B. T., Thastrup, Ole, Leon, A. & Svendsen, U. G., 1987, In: Agents and Actions. 20, 3-4, p. 161-4 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The calcium mobilizing tumor promoting agent, thapsigargin elevates the platelet cytoplasmic free calcium concentration to a higher steady state level. A possible mechanism of action for the tumor promotion

    Thastrup, Ole, Foder, B. & Scharff, O., 1987, In: Biochemical and Biophysical Research Communications. 142, 3, p. 654-60 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    The inflammatory and tumor-promoting sesquiterpene lactone, thapsigargin, activates platelets by selective mobilization of calcium as shown by protein phosphorylations

    Thastrup, Ole, Linnebjerg, H., Bjerrum, P. J., Knudsen, J. B. & Christensen, Søren Brøgger, 1987, In: BBA General Subjects. 927, 1, p. 65-73 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 1988
  17. A novel tumour promoter, thapsigargin, transiently increases cytoplasmic free Ca2+ without generation of inositol phosphates in NG115-401L neuronal cells

    Jackson, T. R., Patterson, S. I., Thastrup, Ole & Hanley, M. R., 1988, In: Biochemical Journal. 253, 1, p. 81-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Effect of thapsigargin on cytoplasmic Ca2+ and proliferation of human lymphocytes in relation to AIDS

    Scharff, O., Foder, B., Thastrup, Ole, Hofmann, B., Møller, J., Ryder, L. P., Jacobsen, K. D., Langhoff, E., Dickmeiss, E. & Christensen, Søren Brøgger, 1988, In: BBA General Subjects. 972, 3, p. 257-64 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Effects of thapsigargin in isolated rat thoracic aorta

    Mikkelsen, E. O., Thastrup, Ole & Christensen, Søren Brøgger, 1988, In: Pharmacology & Toxicology. 62, 1, p. 7-11 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Molecular mechanisms of phospholipid signaling pathways in mammalian nerve cells

    Hanley, M. R., Jackson, T. R., Cheung, W. T., Dreher, M., Gatti, A., Hawkins, P., Patterson, S. I., Vallejo, M., Dawson, A. P. & Thastrup, Ole, 1988, In: Cold Spring Harbor Laboratory. Symposia on Quantitative Biology. 53, Pt 1, p. 435-45 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Neural function: metabolism and actions of inositol metabolites in mammalian brain

    Hanley, M. R., Jackson, T. R., Vallejo, M., Patterson, S. I., Thastrup, Ole, Lightman, S., Rogers, J., Henderson, G. & Pini, A., 1988, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 320, 1199, p. 381-98 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 1989
  23. Activation of calcium entry by the tumor promoter thapsigargin in parotid acinar cells. Evidence that an intracellular calcium pool and not an inositol phosphate regulates calcium fluxes at the plasma membrane

    Takemura, H., Hughes, A. R., Thastrup, Ole & Putney, J. W., 1989, In: Journal of Biological Chemistry. 264, 21, p. 12266-71 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Ca2+ transients and Mn2+ entry in human neutrophils induced by thapsigargin

    Foder, B., Scharff, O. & Thastrup, Ole, 1989, In: Cell Calcium. 10, 7, p. 477-90 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. How do inositol phosphates regulate calcium signaling?

    Putney, J. W., Takemura, H., Hughes, A. R., Horstman, D. A. & Thastrup, Ole, 1989, In: F A S E B Journal. 3, 8, p. 1899-905 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Internal Ca2+ mobilization and secretion in bovine adrenal chromaffin cells

    Cheek, T. R. & Thastrup, Ole, 1989, In: Cell Calcium. 10, 4, p. 213-21 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Thapsigargin, a new calcium-dependent epithelial anion secretagogue

    Brayden, D. J., Hanley, M. R., Thastrup, Ole & Cuthbert, A. W., 1989, In: British Journal of Pharmacology. 98, 3, p. 809-16 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 1990
  29. Calcium efflux across the plasma membrane of rat parotid acinar cells is unaffected by receptor activation or by the microsomal calcium ATPase inhibitor, thapsigargin

    Takemura, H., Thastrup, Ole & Putney, J. W., 1990, In: Cell Calcium. 11, 1, p. 11-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Effects of MeCh, thapsigargin, and La3+ on plasmalemmal and intracellular Ca2+ transport in lacrimal acinar cells

    Kwan, C. Y., Takemura, H., Obie, J. F., Thastrup, Ole & Putney, J. W., 1990, In: American Journal of Physiology (Consolidated). 258, 6 Pt 1, p. C1006-15

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Role of Ca2(+)-ATPases in regulation of cellular Ca2+ signalling, as studied with the selective microsomal Ca2(+)-ATPase inhibitor, thapsigargin

    Thastrup, Ole, 1990, In: Agents and Actions. 29, 1-2, p. 8-15 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase

    Thastrup, Ole, Cullen, P. J., Drøbak, B. K., Hanley, M. R. & Dawson, A. P., 1990, In: Proceedings of the National Academy of Sciences of the United States of America. 87, 7, p. 2466-70 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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