Keeping the rhythm -- pro-arrhythmic investigations in isolated Göttingen minipig hearts
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Keeping the rhythm -- pro-arrhythmic investigations in isolated Göttingen minipig hearts. / Laursen, Morten; Grunnet, Morten; Olesen, Søren-Peter; Jespersen, Thomas; Mow, Tomas.
In: Journal of Pharmacological and Toxicological Methods, Vol. 64, No. 2, 2012, p. 134-44.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Keeping the rhythm -- pro-arrhythmic investigations in isolated Göttingen minipig hearts
AU - Laursen, Morten
AU - Grunnet, Morten
AU - Olesen, Søren-Peter
AU - Jespersen, Thomas
AU - Mow, Tomas
N1 - Copyright © 2011 Elsevier Inc. All rights reserved.
PY - 2012
Y1 - 2012
N2 - Cardiac arrhythmia is a potentially lethal condition. A better prediction and mechanistic understanding of human cardiac arrhythmia is dependent on the development of good animal models. Minipigs are increasingly being used in cardiovascular research and we hypothesize that Langendorff-perfused minipig hearts could serve as a novel model of pro-arrhythmia.
AB - Cardiac arrhythmia is a potentially lethal condition. A better prediction and mechanistic understanding of human cardiac arrhythmia is dependent on the development of good animal models. Minipigs are increasingly being used in cardiovascular research and we hypothesize that Langendorff-perfused minipig hearts could serve as a novel model of pro-arrhythmia.
KW - Adrenergic beta-Agonists
KW - Animals
KW - Arrhythmias, Cardiac
KW - Atrioventricular Block
KW - Disease Models, Animal
KW - Dogs
KW - Electric Stimulation
KW - Electrocardiography
KW - Female
KW - Isoproterenol
KW - Species Specificity
KW - Swine
KW - Swine, Miniature
U2 - 10.1016/j.vascn.2011.05.001
DO - 10.1016/j.vascn.2011.05.001
M3 - Journal article
C2 - 21616157
VL - 64
SP - 134
EP - 144
JO - Journal of Pharmacological and Toxicological Methods
JF - Journal of Pharmacological and Toxicological Methods
SN - 1056-8719
IS - 2
ER -
ID: 40472426